Cbx6 (chromobox 6) - Rat Genome Database

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Gene: Cbx6 (chromobox 6) Rattus norvegicus
Analyze
Symbol: Cbx6
Name: chromobox 6
RGD ID: 1307314
Description: Predicted to enable chromatin binding activity; methylated histone binding activity; and single-stranded RNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nuclear body. Predicted to be part of PRC1 complex and heterochromatin. Orthologous to human CBX6 (chromobox 6); PARTICIPATES IN histone modification pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: chromobox homolog 6; chromobox protein homolog 6; LOC315136
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87113,253,364 - 113,263,413 (-)NCBIGRCr8
mRatBN7.27111,372,979 - 111,383,026 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7111,372,980 - 111,383,091 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7113,120,974 - 113,130,993 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07115,344,512 - 115,354,531 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07115,313,857 - 115,323,876 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07121,047,996 - 121,058,109 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7121,050,302 - 121,058,029 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07121,038,955 - 121,049,097 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47118,062,267 - 118,070,004 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17118,096,504 - 118,104,234 (-)NCBI
Celera7107,705,925 - 107,713,664 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
acrylamide  (ISO)
alpha-pinene  (ISO)
amphetamine  (EXP)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (EXP,ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
cyclosporin A  (ISO)
dicrotophos  (ISO)
dieldrin  (ISO)
dioxygen  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
folic acid  (ISO)
FR900359  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
hydroquinone O-beta-D-glucopyranoside  (ISO)
inulin  (ISO)
iron dichloride  (ISO)
L-methionine  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-nitrosodiethylamine  (EXP)
nickel dichloride  (ISO)
nitrofen  (EXP)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
poly(I:C)  (EXP)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
selenomethionine  (ISO)
silicon dioxide  (ISO)
sulforaphane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. PRC1 complex diversity: where is it taking us? Gil J and O'Loghlen A, Trends Cell Biol. 2014 Jul 22. pii: S0962-8924(14)00102-0. doi: 10.1016/j.tcb.2014.06.005.
3. Altered expression of polycomb group genes in glioblastoma multiforme. Li G, etal., PLoS One. 2013 Nov 15;8(11):e80970. doi: 10.1371/journal.pone.0080970. eCollection 2013.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Occupying chromatin: Polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put. Simon JA and Kingston RE, Mol Cell. 2013 Mar 7;49(5):808-24. doi: 10.1016/j.molcel.2013.02.013.
Additional References at PubMed
PMID:12477932   PMID:16537902   PMID:21282530  


Genomics

Comparative Map Data
Cbx6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87113,253,364 - 113,263,413 (-)NCBIGRCr8
mRatBN7.27111,372,979 - 111,383,026 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7111,372,980 - 111,383,091 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7113,120,974 - 113,130,993 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07115,344,512 - 115,354,531 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07115,313,857 - 115,323,876 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07121,047,996 - 121,058,109 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7121,050,302 - 121,058,029 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07121,038,955 - 121,049,097 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47118,062,267 - 118,070,004 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17118,096,504 - 118,104,234 (-)NCBI
Celera7107,705,925 - 107,713,664 (-)NCBICelera
Cytogenetic Map7q34NCBI
CBX6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382238,861,422 - 38,872,216 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2238,861,422 - 38,872,249 (-)EnsemblGRCh38hg38GRCh38
GRCh372239,257,427 - 39,268,221 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362237,590,189 - 37,598,204 (-)NCBINCBI36Build 36hg18NCBI36
Build 342237,584,749 - 37,592,758NCBI
Celera2223,066,901 - 23,074,916 (-)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2222,225,829 - 22,233,844 (-)NCBIHuRef
CHM1_12239,219,153 - 39,227,168 (-)NCBICHM1_1
T2T-CHM13v2.02239,331,798 - 39,342,593 (-)NCBIT2T-CHM13v2.0
Cbx6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391579,708,099 - 79,718,534 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1579,708,097 - 79,718,889 (-)EnsemblGRCm39 Ensembl
GRCm381579,823,898 - 79,834,333 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1579,823,896 - 79,834,688 (-)EnsemblGRCm38mm10GRCm38
MGSCv371579,654,328 - 79,664,763 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361579,651,153 - 79,661,588 (-)NCBIMGSCv36mm8
Celera1581,943,110 - 81,953,546 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.85NCBI
Cbx6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541324,955,721 - 24,966,973 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541324,955,721 - 24,966,015 (-)NCBIChiLan1.0ChiLan1.0
CBX6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22348,714,786 - 48,726,440 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12251,406,135 - 51,416,940 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02219,774,136 - 19,784,937 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12237,591,216 - 37,602,377 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2237,595,940 - 37,601,679 (-)Ensemblpanpan1.1panPan2
CBX6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11025,967,305 - 25,973,489 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1025,967,300 - 25,988,497 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1025,917,598 - 25,928,682 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01026,752,750 - 26,763,369 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1026,752,754 - 26,791,762 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11026,474,793 - 26,485,867 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01026,785,642 - 26,796,695 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01026,961,989 - 26,973,063 (+)NCBIUU_Cfam_GSD_1.0
Cbx6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049459,511,714 - 9,521,968 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364922,521,553 - 2,532,516 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364922,522,126 - 2,532,382 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CBX6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl59,180,684 - 9,188,620 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.159,180,559 - 9,191,414 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CBX6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11921,525,609 - 21,536,406 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1921,525,596 - 21,536,352 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045104,221,484 - 104,232,319 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cbx6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247529,291,892 - 9,302,688 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247529,291,955 - 9,302,451 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cbx6
17 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:317
Count of miRNA genes:176
Interacting mature miRNAs:218
Transcripts:ENSRNOT00000068033
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat

Markers in Region
BF400141  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27111,381,405 - 111,381,552 (+)MAPPERmRatBN7.2
Rnor_6.07121,056,423 - 121,056,569NCBIRnor6.0
Rnor_5.07121,047,382 - 121,047,528UniSTSRnor5.0
RGSC_v3.47118,068,398 - 118,068,544UniSTSRGSC3.4
Celera7107,712,056 - 107,712,202UniSTS
RH 3.4 Map7855.1UniSTS
Cytogenetic Map7q34UniSTS
AW252195  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27111,375,397 - 111,375,579 (+)MAPPERmRatBN7.2
Rnor_6.07121,050,415 - 121,050,596NCBIRnor6.0
Rnor_5.07121,041,374 - 121,041,555UniSTSRnor5.0
RGSC_v3.47118,062,390 - 118,062,571UniSTSRGSC3.4
Celera7107,706,048 - 107,706,229UniSTS
RH 3.4 Map7856.6UniSTS
Cytogenetic Map7q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 36 16 2 12 2 2 3 74 35 36 11 2
Low 1 7 41 39 7 39 6 8 5 6
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000068033   ⟹   ENSRNOP00000061325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7111,375,263 - 111,383,091 (-)Ensembl
Rnor_6.0 Ensembl7121,050,302 - 121,058,029 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000101445   ⟹   ENSRNOP00000077158
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7111,372,980 - 111,383,024 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000109862   ⟹   ENSRNOP00000093551
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7111,375,265 - 111,383,026 (-)Ensembl
RefSeq Acc Id: NM_001012119   ⟹   NP_001012119
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87113,253,364 - 113,263,413 (-)NCBI
mRatBN7.27111,372,979 - 111,383,026 (-)NCBI
Rnor_6.07121,050,292 - 121,058,029 (-)NCBI
Rnor_5.07121,038,955 - 121,049,097 (-)NCBI
RGSC_v3.47118,062,267 - 118,070,004 (-)RGD
Celera7107,705,925 - 107,713,664 (-)RGD
Sequence:
RefSeq Acc Id: NM_001401046   ⟹   NP_001387975
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87113,253,364 - 113,263,413 (-)NCBI
mRatBN7.27111,372,979 - 111,383,026 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001012119 (Get FASTA)   NCBI Sequence Viewer  
  NP_001387975 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH87122 (Get FASTA)   NCBI Sequence Viewer  
  EDM15778 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000061325
  ENSRNOP00000061325.2
  ENSRNOP00000077158.1
  ENSRNOP00000093551.1
RefSeq Acc Id: NP_001012119   ⟸   NM_001012119
- Peptide Label: isoform 2
- UniProtKB: Q5M9G4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000061325   ⟸   ENSRNOT00000068033
RefSeq Acc Id: ENSRNOP00000077158   ⟸   ENSRNOT00000101445
RefSeq Acc Id: ENSRNOP00000093551   ⟸   ENSRNOT00000109862
RefSeq Acc Id: NP_001387975   ⟸   NM_001401046
- Peptide Label: isoform 1
- UniProtKB: A6HSU4 (UniProtKB/TrEMBL),   E9PT11 (UniProtKB/TrEMBL)
Protein Domains
Chromo

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PT11-F1-model_v2 AlphaFold E9PT11 1-396 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695489
Promoter ID:EPDNEW_R6014
Type:initiation region
Name:Cbx6_1
Description:chromobox 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07121,058,043 - 121,058,103EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307314 AgrOrtholog
BioCyc Gene G2FUF-32742 BioCyc
Ensembl Genes ENSRNOG00000046955 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000068033 ENTREZGENE
  ENSRNOT00000068033.2 UniProtKB/TrEMBL
  ENSRNOT00000101445.1 UniProtKB/TrEMBL
  ENSRNOT00000109862.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.40 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7108347 IMAGE-MGC_LOAD
InterPro CBX7_C UniProtKB/TrEMBL
  Chromo_dom_subgr UniProtKB/TrEMBL
  Chromo_domain UniProtKB/TrEMBL
  Chromo_domain/shadow UniProtKB/TrEMBL
  Chromodomain-like UniProtKB/TrEMBL
  Chromodomain_CS UniProtKB/TrEMBL
KEGG Report rno:315136 UniProtKB/TrEMBL
MGC_CLONE MGC:94814 IMAGE-MGC_LOAD
NCBI Gene 315136 ENTREZGENE
PANTHER CHROMOBOX PROTEIN HOMOLOG 6 UniProtKB/TrEMBL
  POLYCOMB GROUP PROTEIN PC UniProtKB/TrEMBL
Pfam CBX7_C UniProtKB/TrEMBL
  Chromo UniProtKB/TrEMBL
PhenoGen Cbx6 PhenoGen
PRINTS CHROMODOMAIN UniProtKB/TrEMBL
PROSITE CHROMO_1 UniProtKB/TrEMBL
  CHROMO_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000046955 RatGTEx
SMART CHROMO UniProtKB/TrEMBL
Superfamily-SCOP Chromodomain-like UniProtKB/TrEMBL
UniProt A0A8I5Y785_RAT UniProtKB/TrEMBL
  A0A8I6AK19_RAT UniProtKB/TrEMBL
  A6HSU4 ENTREZGENE, UniProtKB/TrEMBL
  E9PT11 ENTREZGENE, UniProtKB/TrEMBL
  Q5M9G4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-02 Cbx6  chromobox 6  Cbx6  chromobox homolog 6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Cbx6  chromobox homolog 6  Cbx6_predicted  chromobox homolog 6 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Cbx6_predicted  chromobox homolog 6 (predicted)      Symbol and Name status set to approved 70820 APPROVED