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Gene: Acvr1b (activin A receptor type 1B) Rattus norvegicus
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Symbol: Acvr1b
Name: activin A receptor type 1B
Description: Predicted to contribute to activin-activated receptor activity and growth factor binding activity. Involved in central nervous system development; development of primary female sexual characteristics; and positive regulation of macromolecule metabolic process. Predicted to localize to the activin receptor complex; cell surface; and cytosol. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human ACVR1B (activin A receptor type 1B); PARTICIPATES IN activin signaling pathway; cytokine mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: activin A receptor, type 1B; activin A receptor, type IB; activin receptor type IB; activin receptor type-1B; activin receptor-like kinase 4; ACTR-IB; ALK-4; Serine/threonine-protein kinase receptor R2; Serine/threonine-protein kinase receptor R2 precursor; Skr2
Orthologs:
Homo sapiens (human) : ACVR1B (activin A receptor type 1B)  HGNC  Alliance
Mus musculus (house mouse) : Acvr1b (activin A receptor, type 1B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acvr1b (activin A receptor type 1B)
Pan paniscus (bonobo/pygmy chimpanzee) : ACVR1B (activin A receptor type 1B)
Canis lupus familiaris (dog) : ACVR1B (activin A receptor type 1B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acvr1b (activin A receptor type 1B)
Sus scrofa (pig) : ACVR1B (activin A receptor type 1B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07142,817,174 - 142,858,365 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7142,817,157 - 142,860,572 (+)Ensembl
Rnor_5.07140,617,642 - 140,659,246 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47139,910,157 - 139,958,740 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17140,015,437 - 140,035,177 (+)NCBI
Celera7128,775,059 - 128,793,132 (+)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Acvr1b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735207
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.