Gene: Slc11a2 (solute carrier family 11 member 2) Rattus norvegicus
Symbol: Slc11a2
Name: solute carrier family 11 member 2
Description: ENCODES a protein that exhibits cadmium ion binding; cadmium ion transmembrane transporter activity; cobalt ion binding; INVOLVED IN cellular copper ion homeostasis; cellular response to hypoxia; cellular response to iron ion; PARTICIPATES IN hypoxia inducible factor pathway; iron uptake pathway; ASSOCIATED WITH abnormal iron homeostasis; ASSOCIATED WITH Anemia, Hypochromic; Anemia, Iron-Deficiency; Brain Ischemia; FOUND IN apical part of cell; cytoplasm; integral component of membrane; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: divalent cation transporter 1; divalent metal transporter 1; DMT-1; DMT1; natural resistance-associated macrophage protein 2; NRAMP 2; Nramp2; solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2; Solute carrier family 11 member 2 (natural resistance-associated macrophage protein 2)
Homo sapiens (human) : SLC11A2 (solute carrier family 11 member 2)  HGNC  AGR
Mus musculus (house mouse) : Slc11a2 (solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2)  MGI  AGR
Pan paniscus (bonobo/pygmy chimpanzee) : SLC11A2 (solute carrier family 11 member 2)
Canis lupus familiaris (dog) : SLC11A2 (solute carrier family 11 member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc11a2 (solute carrier family 11 member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07142,025,812 - 142,062,892 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07139,833,529 - 139,870,819 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47139,094,505 - 139,127,427 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17139,170,941 - 139,203,864 (-)NCBI
Celera7127,985,198 - 128,017,825 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Slc11a2
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3684
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE