SLC11A2 (solute carrier family 11 member 2) - Rat Genome Database

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Gene: SLC11A2 (solute carrier family 11 member 2) Homo sapiens
Analyze
Symbol: SLC11A2
Name: solute carrier family 11 member 2
RGD ID: 737578
HGNC Page HGNC
Description: Enables several functions, including lead ion transmembrane transporter activity; retromer complex binding activity; and transition metal ion transmembrane transporter activity. Involved in several processes, including activation of cysteine-type endopeptidase activity involved in apoptotic process; metal ion transport; and multicellular organismal iron ion homeostasis. Located in several cellular components, including apical plasma membrane; endosome; and trans-Golgi network. Is integral component of plasma membrane. Part of paraferritin complex. Implicated in Parkinson's disease; amyotrophic lateral sclerosis; anemia; and hypochromic anemia. Biomarker of Parkinson's disease and restless legs syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AHMIO1; DCT1; divalent cation transporter 1; DMT-1; DMT1; FLJ37416; natural resistance-associated macrophage protein 2; NRAMP 2; NRAMP2; solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
RGD Orthologs
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1250,979,401 - 51,028,566 (-)EnsemblGRCh38hg38GRCh38
GRCh381250,952,263 - 51,028,886 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371251,373,190 - 51,422,669 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361249,666,044 - 49,706,409 (-)NCBINCBI36hg18NCBI36
Build 341249,666,043 - 49,706,409NCBI
Celera1250,175,791 - 50,224,278 (-)NCBI
Cytogenetic Map12q13.12NCBI
HuRef1248,405,542 - 48,453,948 (-)NCBIHuRef
CHM1_11251,339,878 - 51,388,358 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (EXP)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (ISO)
2-methylcholine  (EXP)
3H-1,2-dithiole-3-thione  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
alcohol  (EXP)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (EXP)
arsane  (EXP)
arsenic atom  (EXP)
astragaloside IV  (EXP)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
captan  (ISO)
chlorogenic acid  (ISO)
chromium(6+)  (ISO)
clobetasol  (ISO)
cobalt atom  (EXP)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (EXP)
copper(II) sulfate  (EXP)
crocidolite asbestos  (EXP)
curcumin  (ISO)
cyclosporin A  (EXP)
D-glucose  (EXP,ISO)
deferiprone  (EXP)
desferrioxamine B  (EXP,ISO)
dibutyl phthalate  (ISO)
diltiazem  (ISO)
dimethylarsinic acid  (ISO)
dioxygen  (EXP,ISO)
divanadium pentaoxide  (ISO)
dorsomorphin  (EXP)
doxorubicin  (ISO)
ebselen  (EXP)
elemental selenium  (EXP)
erastin  (ISO)
ethanol  (ISO)
ferric ammonium citrate  (ISO)
flutamide  (ISO)
folpet  (ISO)
gamma-hexachlorocyclohexane  (ISO)
gentamycin  (ISO)
glafenine  (ISO)
glucose  (EXP,ISO)
hydrogen peroxide  (EXP)
iron atom  (EXP,ISO)
iron dextran  (EXP,ISO)
iron trichloride  (EXP)
iron(0)  (EXP,ISO)
iron(2+) sulfate (anhydrous)  (EXP)
iron(III) nitrilotriacetate  (EXP)
isobutanol  (EXP)
isotretinoin  (EXP)
kainic acid  (ISO)
L-ascorbic acid  (EXP)
lead diacetate  (ISO)
lead(0)  (EXP)
lead(2+)  (EXP)
lead(II) chloride  (ISO)
lipopolysaccharide  (EXP,ISO)
manganese atom  (EXP,ISO)
manganese(0)  (EXP,ISO)
manganese(II) chloride  (EXP,ISO)
mercury atom  (EXP,ISO)
mercury(0)  (EXP,ISO)
methapyrilene  (EXP)
Methylazoxymethanol acetate  (ISO)
methylmercury chloride  (EXP)
mithramycin  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
N-nitrosodiethylamine  (ISO)
nickel atom  (EXP)
nimodipine  (ISO)
nitric oxide  (ISO)
nitroprusside  (EXP)
ochratoxin A  (EXP,ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
paracetamol  (EXP)
phenobarbital  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
quercetin  (EXP,ISO)
SB 431542  (EXP)
selenium atom  (EXP)
silicon dioxide  (ISO)
sodium dichromate  (ISO)
staurosporine  (ISO)
succimer  (EXP,ISO)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (EXP,ISO)
testosterone  (ISO)
titanium dioxide  (ISO)
topotecan  (ISO)
trichloroethene  (ISO)
trichostatin A  (EXP)
trovafloxacin  (ISO)
tunicamycin  (EXP)
undecane  (ISO)
uranium atom  (ISO)
urethane  (EXP)
valproic acid  (EXP,ISO)
vanadium atom  (ISO)
vanadium dioxide  (EXP)
vanadium(0)  (ISO)
verapamil  (ISO)
vitamin E  (EXP,ISO)
Yessotoxin  (EXP)
zinc atom  (EXP,ISO)
zinc dichloride  (EXP)
zinc oxide  (ISO)
zinc sulfate  (EXP)
zinc(0)  (EXP,ISO)
zoledronic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
1. Beaumont C, etal., Blood. 2006 May 15;107(10):4168-70. Epub 2006 Jan 26.
2. Blasco H, etal., J Neurol Sci. 2011 Apr 15;303(1-2):124-7. Epub 2011 Jan 26.
3. Catoire H, etal., Ann Neurol. 2011 Jul;70(1):170-5. doi: 10.1002/ana.22435. Epub 2011 Jun 27.
4. Fleming MD, etal., Nat Genet. 1997 Aug;16(4):383-6.
5. Fleming MD, etal., Proc Natl Acad Sci U S A 1998 Feb 3;95(3):1148-53.
6. GOA_HUMAN data from the GO Consortium
7. He Q, etal., Neurosci Lett. 2011 Sep 1;501(3):128-31. Epub 2011 Jul 12.
8. Jiang H, etal., Cell Res. 2010 Mar;20(3):345-56. Epub 2010 Feb 2.
9. Khomenko T, etal., Am J Physiol Gastrointest Liver Physiol. 2009 Jun;296(6):G1277-86. doi: 10.1152/ajpgi.90257.2008. Epub 2009 Apr 2.
10. Kim J, etal., Am J Physiol Lung Cell Mol Physiol. 2011 Apr;300(4):L659-65. Epub 2011 Jan 28.
11. Lane DJ, etal., Biochim Biophys Acta. 2015 May;1853(5):1130-44. doi: 10.1016/j.bbamcr.2015.01.021. Epub 2015 Feb 4.
12. Mims MP, etal., Blood. 2005 Feb 1;105(3):1337-42. Epub 2004 Sep 30.
13. Moos T and Morgan EH, J Neurochem. 2004 Jan;88(1):233-45.
14. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
15. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. RGD automated import pipeline for gene-chemical interactions
17. RGD automated import pipeline for human HPO-to-gene-to-disease annotations
18. Salazar J, etal., Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18578-83. Epub 2008 Nov 14.
19. Thompson K, etal., FASEB J. 2007 Jan;21(1):223-30. Epub 2006 Nov 20.
20. Xiong L, etal., Am J Med Genet B Neuropsychiatr Genet. 2007 Oct 5;144B(7):911-7.
21. Yang F, etal., Biometals. 2010 Aug;23(4):657-67. Epub 2010 Mar 25.
22. Yang L, etal., Cell Physiol Biochem. 2011;27(1):23-30. Epub 2011 Feb 11.
Additional References at PubMed
PMID:7613023   PMID:9464519   PMID:9642100   PMID:9790986   PMID:9990067   PMID:10625641   PMID:10751401   PMID:10984552   PMID:11095929   PMID:11439223   PMID:11755534   PMID:11842004  
PMID:11891802   PMID:11897618   PMID:11943663   PMID:12127992   PMID:12139757   PMID:12209011   PMID:12475959   PMID:12477932   PMID:12662899   PMID:12734107   PMID:12949720   PMID:12949888  
PMID:12973678   PMID:14702039   PMID:14768003   PMID:15024413   PMID:15139022   PMID:15223008   PMID:15489334   PMID:15636493   PMID:15644277   PMID:15792797   PMID:15880641   PMID:16123094  
PMID:16344560   PMID:17109629   PMID:17293870   PMID:17897319   PMID:17932044   PMID:17980698   PMID:18082289   PMID:18419598   PMID:18667808   PMID:18776082   PMID:18876082   PMID:19490893  
PMID:19679638   PMID:19706893   PMID:19913121   PMID:19946888   PMID:20007457   PMID:20089134   PMID:20152801   PMID:20164305   PMID:20379614   PMID:20410187   PMID:20587610   PMID:20628086  
PMID:20945371   PMID:21074515   PMID:21199652   PMID:21798283   PMID:21871825   PMID:21873635   PMID:21947861   PMID:21948377   PMID:22068728   PMID:22137264   PMID:22154351   PMID:22310887  
PMID:22371024   PMID:22383495   PMID:22509377   PMID:22666436   PMID:22736759   PMID:23016933   PMID:23996061   PMID:24120082   PMID:24344282   PMID:24448823   PMID:24475238   PMID:24742347  
PMID:24914374   PMID:25326704   PMID:25491917   PMID:25562168   PMID:25772431   PMID:25817364   PMID:26067577   PMID:26289753   PMID:26638075   PMID:27117373   PMID:27462458   PMID:27546461  
PMID:27889239   PMID:28367088   PMID:28714470   PMID:28754960   PMID:28762519   PMID:29023457   PMID:29082606   PMID:29178181   PMID:30055235   PMID:30423260   PMID:30527495   PMID:30555088  
PMID:30639242   PMID:30870050   PMID:30959888   PMID:31092704   PMID:31721611   PMID:31804182   PMID:34079125  


Genomics

Comparative Map Data
SLC11A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1250,979,401 - 51,028,566 (-)EnsemblGRCh38hg38GRCh38
GRCh381250,952,263 - 51,028,886 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371251,373,190 - 51,422,669 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361249,666,044 - 49,706,409 (-)NCBINCBI36hg18NCBI36
Build 341249,666,043 - 49,706,409NCBI
Celera1250,175,791 - 50,224,278 (-)NCBI
Cytogenetic Map12q13.12NCBI
HuRef1248,405,542 - 48,453,948 (-)NCBIHuRef
CHM1_11251,339,878 - 51,388,358 (-)NCBICHM1_1
Slc11a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915100,285,779 - 100,322,090 (-)NCBIGRCm39mm39
GRCm39 Ensembl15100,285,779 - 100,322,953 (-)Ensembl
GRCm3815100,387,898 - 100,424,209 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15100,387,898 - 100,425,072 (-)EnsemblGRCm38mm10GRCm38
MGSCv3715100,218,329 - 100,253,486 (-)NCBIGRCm37mm9NCBIm37
MGSCv3615100,215,932 - 100,251,017 (-)NCBImm8
Celera15102,539,003 - 102,574,160 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1556.29NCBI
Slc11a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27131,503,076 - 131,540,246 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl7142,025,815 - 142,063,212 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.07142,025,812 - 142,062,892 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07139,833,529 - 139,870,819 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47139,094,505 - 139,127,427 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17139,170,941 - 139,203,864 (-)NCBI
Celera7127,985,198 - 128,017,825 (-)NCBICelera
Cytogenetic Map7q36NCBI
SLC11A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11238,629,576 - 38,677,377 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1238,629,686 - 38,677,377 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01237,726,158 - 37,774,554 (+)NCBIMhudiblu_PPA_v0panPan3
SLC11A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1273,788,785 - 3,823,852 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl273,787,855 - 3,822,672 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2742,433,184 - 42,468,214 (-)NCBI
ROS_Cfam_1.0273,835,730 - 3,870,717 (+)NCBI
UMICH_Zoey_3.1273,802,428 - 3,837,405 (+)NCBI
UNSW_CanFamBas_1.0273,789,782 - 3,824,709 (+)NCBI
UU_Cfam_GSD_1.02742,829,654 - 42,864,682 (-)NCBI
Slc11a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494564,541,218 - 64,575,407 (+)NCBI
SpeTri2.0NW_0049365128,590,302 - 8,622,121 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC11A2
(Sus scrofa - pig)
No map positions available.
SLC11A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11147,190,138 - 47,238,543 (-)NCBI
ChlSab1.1 Ensembl1147,197,168 - 47,235,130 (-)Ensembl
Vero_WHO_p1.0NW_023666037198,862,999 - 198,915,680 (+)NCBI
Slc11a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248161,345,020 - 1,389,615 (+)NCBI

Position Markers
D12S813  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371251,401,908 - 51,402,164UniSTSGRCh37
Build 361249,688,175 - 49,688,431RGDNCBI36
Celera1250,204,131 - 50,204,387RGD
Cytogenetic Map12q13UniSTS
HuRef1248,433,812 - 48,434,060UniSTS
Marshfield Genetic Map1264.96UniSTS
Marshfield Genetic Map1264.96RGD
D12S1402  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371251,379,805 - 51,379,929UniSTSGRCh37
Build 361249,666,072 - 49,666,196RGDNCBI36
Celera1250,182,029 - 50,182,153RGD
Cytogenetic Map12q13UniSTS
HuRef1248,411,779 - 48,411,903UniSTS
GeneMap99-GB4 RH Map12226.06UniSTS
Whitehead-RH Map12324.1UniSTS
Whitehead-YAC Contig Map12 UniSTS
PMC129447P4  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371251,381,555 - 51,382,072UniSTSGRCh37
Build 361249,667,822 - 49,668,339RGDNCBI36
Celera1250,183,779 - 50,184,296RGD
Cytogenetic Map12q13UniSTS
HuRef1248,413,529 - 48,414,046UniSTS
PMC129447P5  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371251,374,713 - 51,375,374UniSTSGRCh37
Build 361249,660,980 - 49,661,641RGDNCBI36
Celera1250,176,938 - 50,177,599RGD
Cytogenetic Map12q13UniSTS
HuRef1248,406,688 - 48,407,349UniSTS
SLC11A2_739  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371251,379,707 - 51,380,552UniSTSGRCh37
Build 361249,665,974 - 49,666,819RGDNCBI36
Celera1250,181,931 - 50,182,776RGD
HuRef1248,411,681 - 48,412,526UniSTS
RH17780  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371251,380,436 - 51,380,589UniSTSGRCh37
Build 361249,666,703 - 49,666,856RGDNCBI36
Celera1250,182,660 - 50,182,813RGD
Cytogenetic Map12q13UniSTS
HuRef1248,412,410 - 48,412,563UniSTS
GeneMap99-GB4 RH Map12226.06UniSTS
NCBI RH Map12421.8UniSTS
WI-11374  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371251,397,929 - 51,398,052UniSTSGRCh37
Build 361249,684,196 - 49,684,319RGDNCBI36
Celera1250,200,156 - 50,200,279RGD
Cytogenetic Map12q13UniSTS
HuRef1248,429,837 - 48,429,960UniSTS
GeneMap99-GB4 RH Map12226.06UniSTS
Whitehead-RH Map12327.8UniSTS
NCBI RH Map12421.8UniSTS
SHGC-35510  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371251,381,892 - 51,382,102UniSTSGRCh37
Build 361249,668,159 - 49,668,369RGDNCBI36
Celera1250,184,116 - 50,184,326RGD
Cytogenetic Map12q13UniSTS
HuRef1248,413,866 - 48,414,076UniSTS
Stanford-G3 RH Map122017.0UniSTS
GeneMap99-GB4 RH Map12225.96UniSTS
Whitehead-RH Map12327.8UniSTS
GeneMap99-G3 RH Map121963.0UniSTS
WI-22218  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371251,374,787 - 51,374,993UniSTSGRCh37
Build 361249,661,054 - 49,661,260RGDNCBI36
Celera1250,177,012 - 50,177,218RGD
Cytogenetic Map12q13UniSTS
HuRef1248,406,762 - 48,406,968UniSTS
GeneMap99-GB4 RH Map12226.16UniSTS
Whitehead-RH Map12324.1UniSTS
G20510  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371251,379,829 - 51,379,943UniSTSGRCh37
Build 361249,666,096 - 49,666,210RGDNCBI36
Celera1250,182,053 - 50,182,167RGD
Cytogenetic Map12q13UniSTS
HuRef1248,411,803 - 48,411,917UniSTS
A005U25  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371251,379,829 - 51,379,943UniSTSGRCh37
Build 361249,666,096 - 49,666,210RGDNCBI36
Celera1250,182,053 - 50,182,167RGD
Cytogenetic Map12q13UniSTS
HuRef1248,411,803 - 48,411,917UniSTS
GeneMap99-GB4 RH Map12226.06UniSTS
NCBI RH Map12421.8UniSTS
RH45071  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371251,373,633 - 51,373,752UniSTSGRCh37
Build 361249,659,900 - 49,660,019RGDNCBI36
Celera1250,175,858 - 50,175,977RGD
Cytogenetic Map12q13UniSTS
HuRef1248,405,609 - 48,405,728UniSTS
GeneMap99-GB4 RH Map12226.26UniSTS
NCBI RH Map12442.2UniSTS
A006N48  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371251,380,515 - 51,380,649UniSTSGRCh37
Build 361249,666,782 - 49,666,916RGDNCBI36
Celera1250,182,739 - 50,182,873RGD
Cytogenetic Map12q13UniSTS
HuRef1248,412,489 - 48,412,623UniSTS
GeneMap99-GB4 RH Map12226.06UniSTS
NCBI RH Map12415.3UniSTS
RH47542  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371251,379,894 - 51,380,056UniSTSGRCh37
Build 361249,666,161 - 49,666,323RGDNCBI36
Celera1250,182,118 - 50,182,280RGD
Cytogenetic Map12q13UniSTS
HuRef1248,411,868 - 48,412,030UniSTS
GeneMap99-GB4 RH Map12226.06UniSTS
NCBI RH Map12421.8UniSTS
SHGC-33554  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371251,380,370 - 51,380,494UniSTSGRCh37
Build 361249,666,637 - 49,666,761RGDNCBI36
Celera1250,182,594 - 50,182,718RGD
Cytogenetic Map12q13UniSTS
HuRef1248,412,344 - 48,412,468UniSTS
TNG Radiation Hybrid Map1223364.0UniSTS
Stanford-G3 RH Map122021.0UniSTS
GeneMap99-GB4 RH Map12226.16UniSTS
Whitehead-RH Map12322.6UniSTS
NCBI RH Map12442.2UniSTS
GeneMap99-G3 RH Map121967.0UniSTS
L18506  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4q12UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map12q13.2UniSTS
Cytogenetic Map17q22UniSTS
Cytogenetic Map12p12.1UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map1q23.1UniSTS
Cytogenetic Map10p12UniSTS
Cytogenetic Map3q23UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map6p12.1UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map12q13UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map2q32-q34UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map1q22UniSTS
Cytogenetic Map3q29UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map1q25.2UniSTS
Cytogenetic Map3p25.3UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic Map19q13.31UniSTS
Cytogenetic Map10q22.2UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map19p13UniSTS
D12S1249E  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12q13UniSTS
HuRef1248,418,667 - 48,420,297UniSTS
Slc11a2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371251,386,679 - 51,388,354UniSTSGRCh37
Celera1250,188,901 - 50,190,570UniSTS
HuRef1248,418,650 - 48,420,248UniSTS

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIRLET7Dhsa-let-7d-5pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assay//Western blotFunctional MTI20410187
MIR484hsa-miR-484Mirtarbaseexternal_infoCLASHFunctional MTI (Weak)23622248

Predicted Target Of
Summary Value
Count of predictions:5928
Count of miRNA genes:1368
Interacting mature miRNAs:1778
Transcripts:ENST00000262051, ENST00000262052, ENST00000394904, ENST00000541174, ENST00000545993, ENST00000546488, ENST00000546636, ENST00000546743, ENST00000547198, ENST00000547510, ENST00000547579, ENST00000547688, ENST00000547732, ENST00000548150, ENST00000548193, ENST00000548554, ENST00000549110, ENST00000549193, ENST00000549625, ENST00000550061, ENST00000550329, ENST00000550714, ENST00000550782, ENST00000550995, ENST00000551215, ENST00000551231
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1985 1416 1424 364 647 206 3678 1030 2541 283 1322 1603 171 1 1012 2175 5 2
Low 454 1562 302 260 1294 259 678 1164 1193 136 138 10 4 192 613 1
Below cutoff 13 10 1 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_021139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_000617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001174125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001174126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001174127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001174128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001174129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001174130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001379446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001379447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001379448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001379455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_033421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_033422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_166668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_166669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_166670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011538404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011538405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017019356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001748720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_429104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_944555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB004857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB015355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB062284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC008121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC087884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF046997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF064484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH006171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ493662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK094735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK128640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK296445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK315987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK316507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL832886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC002592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC100014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD365137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK000292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA417090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA737206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA957633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB350334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC324894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM365091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM365092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM365093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM365094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM365095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM365096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM365097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM365098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM365099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM365100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM365101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM433694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM433695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM433696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM433697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM433698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM433699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM433700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM433701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM433702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM433703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM433704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM433705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM433706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM433707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP411015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP411016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KR052785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KR052786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KR052787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT455015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L37347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000262052   ⟹   ENSP00000262052
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,985,992 - 51,026,384 (-)Ensembl
RefSeq Acc Id: ENST00000394904   ⟹   ENSP00000378364
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,985,992 - 51,028,566 (-)Ensembl
RefSeq Acc Id: ENST00000541174   ⟹   ENSP00000444542
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,987,946 - 51,026,141 (-)Ensembl
RefSeq Acc Id: ENST00000545993   ⟹   ENSP00000442810
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,988,173 - 51,009,270 (-)Ensembl
RefSeq Acc Id: ENST00000546488   ⟹   ENSP00000450389
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,996,941 - 51,026,384 (-)Ensembl
RefSeq Acc Id: ENST00000546636   ⟹   ENSP00000449008
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,979,820 - 51,026,368 (-)Ensembl
RefSeq Acc Id: ENST00000546743   ⟹   ENSP00000446914
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,988,320 - 51,026,400 (-)Ensembl
RefSeq Acc Id: ENST00000547198   ⟹   ENSP00000446769
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,981,009 - 51,026,338 (-)Ensembl
RefSeq Acc Id: ENST00000547510   ⟹   ENSP00000446653
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,996,871 - 51,026,393 (-)Ensembl
RefSeq Acc Id: ENST00000547579   ⟹   ENSP00000447482
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,996,961 - 51,026,391 (-)Ensembl
RefSeq Acc Id: ENST00000547688   ⟹   ENSP00000449200
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,988,325 - 51,028,241 (-)Ensembl
RefSeq Acc Id: ENST00000547732   ⟹   ENSP00000447102
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1251,000,318 - 51,026,363 (-)Ensembl
RefSeq Acc Id: ENST00000548150   ⟹   ENSP00000448273
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1251,010,720 - 51,024,843 (-)Ensembl
RefSeq Acc Id: ENST00000548193   ⟹   ENSP00000449209
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1251,000,402 - 51,026,384 (-)Ensembl
RefSeq Acc Id: ENST00000548554
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,990,584 - 50,991,667 (-)Ensembl
RefSeq Acc Id: ENST00000549110
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1251,000,350 - 51,005,848 (-)Ensembl
RefSeq Acc Id: ENST00000549193
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1251,005,322 - 51,009,168 (-)Ensembl
RefSeq Acc Id: ENST00000549625   ⟹   ENSP00000448501
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1251,005,319 - 51,026,384 (-)Ensembl
RefSeq Acc Id: ENST00000550061
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,995,684 - 50,999,565 (-)Ensembl
RefSeq Acc Id: ENST00000550329
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1251,008,145 - 51,026,379 (-)Ensembl
RefSeq Acc Id: ENST00000550714   ⟹   ENSP00000446984
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,999,368 - 51,026,384 (-)Ensembl
RefSeq Acc Id: ENST00000550782
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,985,993 - 50,995,092 (-)Ensembl
RefSeq Acc Id: ENST00000550995
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1251,005,404 - 51,026,365 (-)Ensembl
RefSeq Acc Id: ENST00000551215   ⟹   ENSP00000450227
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,979,401 - 50,992,209 (-)Ensembl
RefSeq Acc Id: ENST00000551231
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,991,599 - 50,993,144 (-)Ensembl
RefSeq Acc Id: ENST00000642227   ⟹   ENSP00000494696
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,986,164 - 51,026,351 (-)Ensembl
RefSeq Acc Id: ENST00000643123
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,986,071 - 51,026,351 (-)Ensembl
RefSeq Acc Id: ENST00000643884   ⟹   ENSP00000493633
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,979,809 - 51,026,339 (-)Ensembl
RefSeq Acc Id: ENST00000644495   ⟹   ENSP00000494107
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,979,784 - 51,026,384 (-)Ensembl
RefSeq Acc Id: ENST00000646264   ⟹   ENSP00000494744
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,981,438 - 51,000,418 (-)Ensembl
RefSeq Acc Id: ENST00000646740   ⟹   ENSP00000494001
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1250,986,081 - 51,026,351 (-)Ensembl
RefSeq Acc Id: ENST00000646988   ⟹   ENSP00000494619
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1251,004,838 - 51,025,781 (-)Ensembl
RefSeq Acc Id: ENST00000681324   ⟹   ENSP00000505087
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1251,005,376 - 51,028,566 (-)Ensembl
RefSeq Acc Id: NM_000617   ⟹   NP_000608
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,985,992 - 51,026,384 (-)NCBI
GRCh371251,373,566 - 51,422,118 (-)NCBI
Build 361249,666,044 - 49,706,409 (-)NCBI Archive
HuRef1248,405,542 - 48,453,948 (-)ENTREZGENE
CHM1_11251,346,086 - 51,386,502 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001174125   ⟹   NP_001167596
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,985,992 - 51,028,242 (-)NCBI
GRCh371251,373,566 - 51,422,118 (-)NCBI
HuRef1248,405,542 - 48,453,948 (-)ENTREZGENE
CHM1_11251,346,086 - 51,388,358 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001174126   ⟹   NP_001167597
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,979,784 - 51,026,384 (-)NCBI
GRCh371251,373,566 - 51,422,118 (-)NCBI
HuRef1248,405,542 - 48,453,948 (-)ENTREZGENE
CHM1_11251,339,878 - 51,386,502 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001174127   ⟹   NP_001167598
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,979,784 - 51,026,384 (-)NCBI
GRCh371251,373,566 - 51,422,118 (-)NCBI
HuRef1248,405,542 - 48,453,948 (-)ENTREZGENE
CHM1_11251,339,878 - 51,386,502 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001174128   ⟹   NP_001167599
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,985,992 - 51,026,384 (-)NCBI
GRCh371251,373,566 - 51,422,118 (-)NCBI
HuRef1248,405,542 - 48,453,948 (-)ENTREZGENE
CHM1_11251,346,086 - 51,386,502 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001174129   ⟹   NP_001167600
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,985,992 - 51,026,141 (-)NCBI
GRCh371251,373,566 - 51,422,118 (-)NCBI
HuRef1248,405,542 - 48,453,948 (-)ENTREZGENE
CHM1_11251,346,086 - 51,386,227 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001174130   ⟹   NP_001167601
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,985,992 - 51,009,215 (-)NCBI
GRCh371251,373,566 - 51,422,118 (-)NCBI
HuRef1248,405,542 - 48,453,948 (-)ENTREZGENE
CHM1_11251,346,086 - 51,369,361 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001379446   ⟹   NP_001366375
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,979,784 - 51,028,242 (-)NCBI
RefSeq Acc Id: NM_001379447   ⟹   NP_001366376
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,979,784 - 51,026,150 (-)NCBI
RefSeq Acc Id: NM_001379448   ⟹   NP_001366377
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,979,784 - 51,009,215 (-)NCBI
RefSeq Acc Id: NM_001379455   ⟹   NP_001366384
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,985,992 - 51,028,886 (-)NCBI
RefSeq Acc Id: NR_033421
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,985,992 - 51,026,384 (-)NCBI
GRCh371251,373,566 - 51,422,118 (-)NCBI
HuRef1248,405,542 - 48,453,948 (-)ENTREZGENE
CHM1_11251,346,086 - 51,386,502 (-)NCBI
Sequence:
RefSeq Acc Id: NR_033422
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,979,784 - 51,026,384 (-)NCBI
GRCh371251,373,566 - 51,422,118 (-)NCBI
HuRef1248,405,542 - 48,453,948 (-)ENTREZGENE
CHM1_11251,339,878 - 51,386,502 (-)NCBI
Sequence:
RefSeq Acc Id: NR_166668
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,979,407 - 51,026,384 (-)NCBI
RefSeq Acc Id: NR_166669
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,979,407 - 51,026,384 (-)NCBI
RefSeq Acc Id: NR_166670
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,979,784 - 51,026,384 (-)NCBI
RefSeq Acc Id: XM_011538404   ⟹   XP_011536706
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,981,007 - 51,024,843 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011538405   ⟹   XP_011536707
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,981,007 - 51,026,384 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017019356   ⟹   XP_016874845
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,981,007 - 51,026,365 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001748720
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,952,263 - 51,028,335 (-)NCBI
Sequence:
RefSeq Acc Id: XR_429104
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,979,784 - 51,028,335 (-)NCBI
Sequence:
RefSeq Acc Id: XR_944555
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,979,410 - 51,028,335 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_000608 (Get FASTA)   NCBI Sequence Viewer  
  NP_001167596 (Get FASTA)   NCBI Sequence Viewer  
  NP_001167597 (Get FASTA)   NCBI Sequence Viewer  
  NP_001167598 (Get FASTA)   NCBI Sequence Viewer  
  NP_001167599 (Get FASTA)   NCBI Sequence Viewer  
  NP_001167600 (Get FASTA)   NCBI Sequence Viewer  
  NP_001167601 (Get FASTA)   NCBI Sequence Viewer  
  NP_001366375 (Get FASTA)   NCBI Sequence Viewer  
  NP_001366376 (Get FASTA)   NCBI Sequence Viewer  
  NP_001366377 (Get FASTA)   NCBI Sequence Viewer  
  NP_001366384 (Get FASTA)   NCBI Sequence Viewer  
  XP_011536706 (Get FASTA)   NCBI Sequence Viewer  
  XP_011536707 (Get FASTA)   NCBI Sequence Viewer  
  XP_016874845 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA79219 (Get FASTA)   NCBI Sequence Viewer  
  AAC18078 (Get FASTA)   NCBI Sequence Viewer  
  AAC21459 (Get FASTA)   NCBI Sequence Viewer  
  AAC21460 (Get FASTA)   NCBI Sequence Viewer  
  AAC21461 (Get FASTA)   NCBI Sequence Viewer  
  AAH02592 (Get FASTA)   NCBI Sequence Viewer  
  AAI00015 (Get FASTA)   NCBI Sequence Viewer  
  AIY26913 (Get FASTA)   NCBI Sequence Viewer  
  AIY26914 (Get FASTA)   NCBI Sequence Viewer  
  AIY26915 (Get FASTA)   NCBI Sequence Viewer  
  AIY26916 (Get FASTA)   NCBI Sequence Viewer  
  AIY26917 (Get FASTA)   NCBI Sequence Viewer  
  AIY26918 (Get FASTA)   NCBI Sequence Viewer  
  AIY26919 (Get FASTA)   NCBI Sequence Viewer  
  AIY26920 (Get FASTA)   NCBI Sequence Viewer  
  AIY26921 (Get FASTA)   NCBI Sequence Viewer  
  AIY26922 (Get FASTA)   NCBI Sequence Viewer  
  AIY26923 (Get FASTA)   NCBI Sequence Viewer  
  AIY30320 (Get FASTA)   NCBI Sequence Viewer  
  AIY30321 (Get FASTA)   NCBI Sequence Viewer  
  AIY30322 (Get FASTA)   NCBI Sequence Viewer  
  AIY30323 (Get FASTA)   NCBI Sequence Viewer  
  AIY30324 (Get FASTA)   NCBI Sequence Viewer  
  AIY30325 (Get FASTA)   NCBI Sequence Viewer  
  AIY30326 (Get FASTA)   NCBI Sequence Viewer  
  AKK25335 (Get FASTA)   NCBI Sequence Viewer  
  AKK25336 (Get FASTA)   NCBI Sequence Viewer  
  AKK25337 (Get FASTA)   NCBI Sequence Viewer  
  AMC33105 (Get FASTA)   NCBI Sequence Viewer  
  BAA24933 (Get FASTA)   NCBI Sequence Viewer  
  BAA34374 (Get FASTA)   NCBI Sequence Viewer  
  BAB93467 (Get FASTA)   NCBI Sequence Viewer  
  BAG52920 (Get FASTA)   NCBI Sequence Viewer  
  BAG54706 (Get FASTA)   NCBI Sequence Viewer  
  BAG59096 (Get FASTA)   NCBI Sequence Viewer  
  BAH14358 (Get FASTA)   NCBI Sequence Viewer  
  BAH14878 (Get FASTA)   NCBI Sequence Viewer  
  CAD38517 (Get FASTA)   NCBI Sequence Viewer  
  EAW58159 (Get FASTA)   NCBI Sequence Viewer  
  EAW58160 (Get FASTA)   NCBI Sequence Viewer  
  EAW58161 (Get FASTA)   NCBI Sequence Viewer  
  EAW58162 (Get FASTA)   NCBI Sequence Viewer  
  EAW58163 (Get FASTA)   NCBI Sequence Viewer  
  EAW58164 (Get FASTA)   NCBI Sequence Viewer  
  EAW58165 (Get FASTA)   NCBI Sequence Viewer  
  P49281 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001167598   ⟸   NM_001174127
- Peptide Label: isoform 2
- UniProtKB: P49281 (UniProtKB/Swiss-Prot),   A0A0X8GKR4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001167597   ⟸   NM_001174126
- Peptide Label: isoform 2
- UniProtKB: P49281 (UniProtKB/Swiss-Prot),   A0A0X8GKR4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001167596   ⟸   NM_001174125
- Peptide Label: isoform 1
- UniProtKB: P49281 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001167599   ⟸   NM_001174128
- Peptide Label: isoform 3
- UniProtKB: P49281 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_000608   ⟸   NM_000617
- Peptide Label: isoform 3
- UniProtKB: P49281 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001167600   ⟸   NM_001174129
- Peptide Label: isoform 3
- UniProtKB: P49281 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001167601   ⟸   NM_001174130
- Peptide Label: isoform 4
- UniProtKB: P49281 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011536707   ⟸   XM_011538405
- Peptide Label: isoform X2
- UniProtKB: P49281 (UniProtKB/Swiss-Prot),   A0A0X8GKR4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011536706   ⟸   XM_011538404
- Peptide Label: isoform X2
- UniProtKB: P49281 (UniProtKB/Swiss-Prot),   A0A0X8GKR4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016874845   ⟸   XM_017019356
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: NP_001366375   ⟸   NM_001379446
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001366376   ⟸   NM_001379447
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001366377   ⟸   NM_001379448
- Peptide Label: isoform 6
RefSeq Acc Id: NP_001366384   ⟸   NM_001379455
- Peptide Label: isoform 1
RefSeq Acc Id: ENSP00000444542   ⟸   ENST00000541174
RefSeq Acc Id: ENSP00000442810   ⟸   ENST00000545993
RefSeq Acc Id: ENSP00000449008   ⟸   ENST00000546636
RefSeq Acc Id: ENSP00000450389   ⟸   ENST00000546488
RefSeq Acc Id: ENSP00000446914   ⟸   ENST00000546743
RefSeq Acc Id: ENSP00000446653   ⟸   ENST00000547510
RefSeq Acc Id: ENSP00000447482   ⟸   ENST00000547579
RefSeq Acc Id: ENSP00000447102   ⟸   ENST00000547732
RefSeq Acc Id: ENSP00000449200   ⟸   ENST00000547688
RefSeq Acc Id: ENSP00000446769   ⟸   ENST00000547198
RefSeq Acc Id: ENSP00000449209   ⟸   ENST00000548193
RefSeq Acc Id: ENSP00000448273   ⟸   ENST00000548150
RefSeq Acc Id: ENSP00000448501   ⟸   ENST00000549625
RefSeq Acc Id: ENSP00000494696   ⟸   ENST00000642227
RefSeq Acc Id: ENSP00000446984   ⟸   ENST00000550714
RefSeq Acc Id: ENSP00000450227   ⟸   ENST00000551215
RefSeq Acc Id: ENSP00000262052   ⟸   ENST00000262052
RefSeq Acc Id: ENSP00000493633   ⟸   ENST00000643884
RefSeq Acc Id: ENSP00000494107   ⟸   ENST00000644495
RefSeq Acc Id: ENSP00000378364   ⟸   ENST00000394904
RefSeq Acc Id: ENSP00000494619   ⟸   ENST00000646988
RefSeq Acc Id: ENSP00000494744   ⟸   ENST00000646264
RefSeq Acc Id: ENSP00000494001   ⟸   ENST00000646740
RefSeq Acc Id: ENSP00000505087   ⟸   ENST00000681324

Promoters
RGD ID:6810410
Promoter ID:HG_ACW:16964
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   HeLa_S3,   K562,   Lymphoblastoid
Transcripts:SLC11A2.VIAPR07
Position:
Human AssemblyChrPosition (strand)Source
Build 361249,704,771 - 49,705,271 (-)MPROMDB
RGD ID:6790346
Promoter ID:HG_KWN:15641
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_000617,   NM_001174128,   NM_001174129,   NR_033421,   NR_033422,   UC001RXC.2,   UC001RXD.2,   UC001RXE.2
Position:
Human AssemblyChrPosition (strand)Source
Build 361249,706,239 - 49,706,739 (-)MPROMDB
RGD ID:6790480
Promoter ID:HG_KWN:15642
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3,   K562
Transcripts:NM_001174125
Position:
Human AssemblyChrPosition (strand)Source
Build 361249,708,211 - 49,708,732 (-)MPROMDB
RGD ID:7223913
Promoter ID:EPDNEW_H17702
Type:initiation region
Name:SLC11A2_2
Description:solute carrier family 11 member 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H17703  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381251,009,215 - 51,009,275EPDNEW
RGD ID:7223915
Promoter ID:EPDNEW_H17703
Type:initiation region
Name:SLC11A2_1
Description:solute carrier family 11 member 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H17702  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381251,026,384 - 51,026,444EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_000617.3(SLC11A2):c.310-5_310-3del microsatellite Anemia, hypochromic microcytic, with iron overload 1 [RCV000009643] Chr12:51004910..51004912 [GRCh38]
Chr12:51398693..51398695 [GRCh37]
Chr12:12q13.12
pathogenic
SLC11A2, 3-BP DEL, 428GTG deletion Anemia, hypochromic microcytic, with iron overload 1 [RCV000009645] Chr12:12q13 pathogenic
NM_000617.3(SLC11A2):c.1197G>C (p.Glu399Asp) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000009642] Chr12:50992810 [GRCh38]
Chr12:51386593 [GRCh37]
Chr12:12q13.12
pathogenic|uncertain significance
NM_000617.3(SLC11A2):c.1246C>T (p.Arg416Cys) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000009644] Chr12:50992291 [GRCh38]
Chr12:51386074 [GRCh37]
Chr12:12q13.12
pathogenic
NM_000617.3(SLC11A2):c.635G>T (p.Gly212Val) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000009646] Chr12:50999214 [GRCh38]
Chr12:51392997 [GRCh37]
Chr12:12q13.12
pathogenic
NM_001174125.1(SLC11A2):c.1447C>T (p.Leu483Phe) single nucleotide variant Malignant melanoma [RCV000070028] Chr12:50991660 [GRCh38]
Chr12:51385443 [GRCh37]
Chr12:49671710 [NCBI36]
Chr12:12q13.12
not provided
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3 copy number gain See cases [RCV000139555] Chr12:121271..133196807 [GRCh38]
Chr12:282465..133773393 [GRCh37]
Chr12:100698..132283466 [NCBI36]
Chr12:12p13.33-q24.33
pathogenic
GRCh38/hg38 12q13.12-13.13(chr12:50633888-52851909)x1 copy number loss See cases [RCV000140716] Chr12:50633888..52851909 [GRCh38]
Chr12:51027671..53245693 [GRCh37]
Chr12:49313938..51531960 [NCBI36]
Chr12:12q13.12-13.13
pathogenic
GRCh38/hg38 12q13.12-13.13(chr12:50122359-53248460)x1 copy number loss See cases [RCV000142033] Chr12:50122359..53248460 [GRCh38]
Chr12:50516142..53642244 [GRCh37]
Chr12:48802409..51928511 [NCBI36]
Chr12:12q13.12-13.13
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:1-133851895)x3 copy number gain See cases [RCV000258805] Chr12:1..133851895 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic|likely pathogenic
GRCh38/hg38 12q13.12(chr12:50600204-50953386)x3 copy number gain See cases [RCV000141166] Chr12:50600204..50953386 [GRCh38]
Chr12:50993987..51347169 [GRCh37]
Chr12:49280254..49633436 [NCBI36]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*2320del deletion Anemia, hypochromic microcytic, with iron overload 1 [RCV000282206] Chr12:50986005 [GRCh38]
Chr12:51379788 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.1425C>T (p.Gly475=) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000301986]|not provided [RCV000924501] Chr12:50990945 [GRCh38]
Chr12:51384728 [GRCh37]
Chr12:12q13.12
likely benign|uncertain significance
NM_000617.3(SLC11A2):c.1258A>G (p.Ile420Val) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000323759] Chr12:50992279 [GRCh38]
Chr12:51386062 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*1949A>G single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000286132] Chr12:50986376 [GRCh38]
Chr12:51380159 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.-39G>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000303511] Chr12:51026310 [GRCh38]
Chr12:51420093 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.1206G>A (p.Leu402=) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000270321] Chr12:50992331 [GRCh38]
Chr12:51386114 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*546G>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000286970] Chr12:50987779 [GRCh38]
Chr12:51381562 [GRCh37]
Chr12:12q13.12
likely benign|uncertain significance
NM_000617.3(SLC11A2):c.*390G>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000290392] Chr12:50987935 [GRCh38]
Chr12:51381718 [GRCh37]
Chr12:12q13.12
benign
NM_000617.3(SLC11A2):c.1254T>C (p.Ile418=) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000380724] Chr12:50992283 [GRCh38]
Chr12:51386066 [GRCh37]
Chr12:12q13.12
benign
NM_000617.3(SLC11A2):c.*1273G>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000275703] Chr12:50987052 [GRCh38]
Chr12:51380835 [GRCh37]
Chr12:12q13.12
benign
NM_000617.3(SLC11A2):c.*1031G>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000261421] Chr12:50987294 [GRCh38]
Chr12:51381077 [GRCh37]
Chr12:12q13.12
benign
NM_000617.3(SLC11A2):c.*1261G>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000314469] Chr12:50987064 [GRCh38]
Chr12:51380847 [GRCh37]
Chr12:12q13.12
benign|uncertain significance
NM_000617.3(SLC11A2):c.*2289G>T single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000339608] Chr12:50986036 [GRCh38]
Chr12:51379819 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.1576-14A>G single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000263234] Chr12:50988449 [GRCh38]
Chr12:51382232 [GRCh37]
Chr12:12q13.12
benign
NM_000617.3(SLC11A2):c.1596A>C (p.Ala532=) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000298296] Chr12:50988415 [GRCh38]
Chr12:51382198 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.1348-10T>C single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000266870] Chr12:50991682 [GRCh38]
Chr12:51385465 [GRCh37]
Chr12:12q13.12
likely benign|uncertain significance
NM_000617.3(SLC11A2):c.197G>A (p.Ser66Asn) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000281257] Chr12:51005423 [GRCh38]
Chr12:51399206 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.1663G>A (p.Ala555Thr) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000390498] Chr12:50988348 [GRCh38]
Chr12:51382131 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*358A>G single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000347715] Chr12:50987967 [GRCh38]
Chr12:51381750 [GRCh37]
Chr12:12q13.12
benign
NM_000617.3(SLC11A2):c.436C>G (p.Arg146Gly) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000395991] Chr12:51000413 [GRCh38]
Chr12:51394196 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*153A>G single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000397447] Chr12:50988172 [GRCh38]
Chr12:51381955 [GRCh37]
Chr12:12q13.12
likely benign|uncertain significance
NM_000617.3(SLC11A2):c.*1752dup duplication Anemia, hypochromic microcytic, with iron overload 1 [RCV000308330] Chr12:50986572..50986573 [GRCh38]
Chr12:51380355..51380356 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.932A>G (p.Asn311Ser) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000327709] Chr12:50995687 [GRCh38]
Chr12:51389470 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.625G>A (p.Ala209Thr) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000349704]|not provided [RCV000972501] Chr12:50999224 [GRCh38]
Chr12:51393007 [GRCh37]
Chr12:12q13.12
benign|uncertain significance
NM_000617.3(SLC11A2):c.*1559G>T single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000398478] Chr12:50986766 [GRCh38]
Chr12:51380549 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.-110G>T single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000307255] Chr12:51026381 [GRCh38]
Chr12:51420164 [GRCh37]
Chr12:12q13.12
benign
NM_000617.3(SLC11A2):c.-78G>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000400710] Chr12:51026349 [GRCh38]
Chr12:51420132 [GRCh37]
Chr12:12q13.12
benign|likely benign
NM_000617.3(SLC11A2):c.*11G>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000352111] Chr12:50988314 [GRCh38]
Chr12:51382097 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*1215A>C single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000352983] Chr12:50987110 [GRCh38]
Chr12:51380893 [GRCh37]
Chr12:12q13.12
benign|likely benign
NM_000617.3(SLC11A2):c.*1466dup duplication Anemia, hypochromic microcytic, with iron overload 1 [RCV000369027] Chr12:50986858..50986859 [GRCh38]
Chr12:51380641..51380642 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*985G>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000264836] Chr12:50987340 [GRCh38]
Chr12:51381123 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.1584A>G (p.Gln528=) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000355564] Chr12:50988427 [GRCh38]
Chr12:51382210 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*872A>C single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000379164] Chr12:50987453 [GRCh38]
Chr12:51381236 [GRCh37]
Chr12:12q13.12
benign|uncertain significance
NM_000617.3(SLC11A2):c.*1486G>T single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000312030] Chr12:50986839 [GRCh38]
Chr12:51380622 [GRCh37]
Chr12:12q13.12
benign|uncertain significance
NM_000617.3(SLC11A2):c.*415G>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000382664] Chr12:50987910 [GRCh38]
Chr12:51381693 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.504A>G (p.Ser168=) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000335030]|not provided [RCV000965959] Chr12:51000345 [GRCh38]
Chr12:51394128 [GRCh37]
Chr12:12q13.12
benign|uncertain significance
NM_000617.3(SLC11A2):c.921C>T (p.Ser307=) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000384554] Chr12:50995698 [GRCh38]
Chr12:51389481 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.34+11G>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000338368] Chr12:51010684 [GRCh38]
Chr12:51404467 [GRCh37]
Chr12:12q13.12
benign
NM_000617.3(SLC11A2):c.607+12G>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000387974] Chr12:50999333 [GRCh38]
Chr12:51393116 [GRCh37]
Chr12:12q13.12
benign
NM_000617.3(SLC11A2):c.*1876T>C single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000390175] Chr12:50986449 [GRCh38]
Chr12:51380232 [GRCh37]
Chr12:12q13.12
benign
NM_000617.3(SLC11A2):c.-38-3C>T single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000400577] Chr12:51010769 [GRCh38]
Chr12:51404552 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.647C>T (p.Thr216Ile) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000292543] Chr12:50999202 [GRCh38]
Chr12:51392985 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*1599C>T single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000347005] Chr12:50986726 [GRCh38]
Chr12:51380509 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*1007A>G single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000318921] Chr12:50987318 [GRCh38]
Chr12:51381101 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_001174125.2(SLC11A2):c.49+1746C>T single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000346152] Chr12:51026431 [GRCh38]
Chr12:51420214 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.514A>G (p.Ile172Val) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000296429] Chr12:51000335 [GRCh38]
Chr12:51394118 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*970A>G single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000322306] Chr12:50987355 [GRCh38]
Chr12:51381138 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*986C>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000375838] Chr12:50987339 [GRCh38]
Chr12:51381122 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.1421+8T>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000359227] Chr12:50991591 [GRCh38]
Chr12:51385374 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*2083_*2084del deletion Anemia, hypochromic microcytic, with iron overload 1 [RCV000395329] Chr12:50986241..50986242 [GRCh38]
Chr12:51380024..51380025 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_001174125.2(SLC11A2):c.49+1757C>T single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000288754] Chr12:51026420 [GRCh38]
Chr12:51420203 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*32A>G single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000312809] Chr12:50988293 [GRCh38]
Chr12:51382076 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*1902C>G single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000343382] Chr12:50986423 [GRCh38]
Chr12:51380206 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*420G>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000344438] Chr12:50987905 [GRCh38]
Chr12:51381688 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.-50G>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000360540] Chr12:51026321 [GRCh38]
Chr12:51420104 [GRCh37]
Chr12:12q13.12
uncertain significance
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902)x3 copy number gain See cases [RCV000510482] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902) copy number gain See cases [RCV000511643] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
NM_000617.3(SLC11A2):c.1422-18T>A single nucleotide variant not provided [RCV000514594] Chr12:50990966 [GRCh38]
Chr12:51384749 [GRCh37]
Chr12:12q13.12
likely benign
GRCh37/hg19 12q13.12-13.13(chr12:51361462-51751521)x3 copy number gain not provided [RCV000683429] Chr12:51361462..51751521 [GRCh37]
Chr12:12q13.12-13.13
uncertain significance
NC_000012.11:g.26370251_54361538inv inversion not specified [RCV000714265] Chr12:26370251..54361538 [GRCh37]
Chr12:12p12.1-q13.13
uncertain significance
GRCh37/hg19 12p13.33-q24.33(chr12:191619-133777645)x3 copy number gain not provided [RCV000750246] Chr12:191619..133777645 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12q13.12(chr12:51029262-51443724)x3 copy number gain not provided [RCV000737883] Chr12:51029262..51443724 [GRCh37]
Chr12:12q13.12
likely benign
GRCh37/hg19 12p13.33-q24.33(chr12:621220-133779118)x3 copy number gain not provided [RCV000750253] Chr12:621220..133779118 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
NM_000617.3(SLC11A2):c.523C>T (p.Leu175=) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001114233] Chr12:51000326 [GRCh38]
Chr12:51394109 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.715G>A (p.Gly239Ser) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000791116] Chr12:50996933 [GRCh38]
Chr12:51390716 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.747C>T (p.Arg249=) single nucleotide variant not provided [RCV000901823] Chr12:50996901 [GRCh38]
Chr12:51390684 [GRCh37]
Chr12:12q13.12
likely benign
NM_000617.3(SLC11A2):c.1032C>G (p.Leu344=) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001112872]|not provided [RCV000938756] Chr12:50994589 [GRCh38]
Chr12:51388372 [GRCh37]
Chr12:12q13.12
likely benign|uncertain significance
NM_000617.3(SLC11A2):c.223G>A (p.Gly75Arg) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV000984996] Chr12:51005397 [GRCh38]
Chr12:51399180 [GRCh37]
Chr12:12q13.12
likely pathogenic
NM_000617.3(SLC11A2):c.*295G>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001114153] Chr12:50988030 [GRCh38]
Chr12:51381813 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.290G>C (p.Gly97Ala) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001114234] Chr12:51005330 [GRCh38]
Chr12:51399113 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.255G>T (p.Leu85=) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001114235] Chr12:51005365 [GRCh38]
Chr12:51399148 [GRCh37]
Chr12:12q13.12
benign
NM_000617.3(SLC11A2):c.*716G>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001112800] Chr12:50987609 [GRCh38]
Chr12:51381392 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.893T>C (p.Ile298Thr) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001112873] Chr12:50995726 [GRCh38]
Chr12:51389509 [GRCh37]
Chr12:12q13.12
benign
NM_000617.3(SLC11A2):c.828C>G (p.Val276=) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001112875] Chr12:50996820 [GRCh38]
Chr12:51390603 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.1303C>A (p.Leu435Ile) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001110875] Chr12:50992234 [GRCh38]
Chr12:51386017 [GRCh37]
Chr12:12q13.12
likely benign
NM_000617.3(SLC11A2):c.1049C>T (p.Ser350Leu) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001110876] Chr12:50994572 [GRCh38]
Chr12:51388355 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_001174125.2(SLC11A2):c.49+1791C>T single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001110957] Chr12:51026386 [GRCh38]
Chr12:51420169 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*2332A>T single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001109938] Chr12:50985993 [GRCh38]
Chr12:51379776 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*1444C>T single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001110030] Chr12:50986881 [GRCh38]
Chr12:51380664 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*1360A>G single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001110032] Chr12:50986965 [GRCh38]
Chr12:51380748 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.-39+12G>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001110206] Chr12:51026298 [GRCh38]
Chr12:51420081 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_001174125.2(SLC11A2):c.49+10C>G single nucleotide variant not provided [RCV000957060] Chr12:51028167 [GRCh38]
Chr12:51421950 [GRCh37]
Chr12:12q13.12
benign
NM_000617.3(SLC11A2):c.*1058G>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001110033] Chr12:50987267 [GRCh38]
Chr12:51381050 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.1655C>T (p.Thr552Ile) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001110116] Chr12:50988356 [GRCh38]
Chr12:51382139 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.1511A>G (p.His504Arg) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001110118] Chr12:50990859 [GRCh38]
Chr12:51384642 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.184T>C (p.Tyr62His) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001110203] Chr12:51005436 [GRCh38]
Chr12:51399219 [GRCh37]
Chr12:12q13.12
benign
NM_000617.3(SLC11A2):c.34+6T>G single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001110204] Chr12:51010689 [GRCh38]
Chr12:51404472 [GRCh37]
Chr12:12q13.12
benign
NM_000617.3(SLC11A2):c.832-3T>C single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001112874] Chr12:50995790 [GRCh38]
Chr12:51389573 [GRCh37]
Chr12:12q13.12
likely benign
NM_000617.3(SLC11A2):c.*1615T>C single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001112711] Chr12:50986710 [GRCh38]
Chr12:51380493 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*789G>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001112799] Chr12:50987536 [GRCh38]
Chr12:51381319 [GRCh37]
Chr12:12q13.12
benign
NM_000617.3(SLC11A2):c.*1367T>C single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001110031] Chr12:50986958 [GRCh38]
Chr12:51380741 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*1057C>T single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001110034] Chr12:50987268 [GRCh38]
Chr12:51381051 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.1576-7C>G single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001110117] Chr12:50988442 [GRCh38]
Chr12:51382225 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.15T>C (p.Pro5=) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001110205] Chr12:51010714 [GRCh38]
Chr12:51404497 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.-39+5G>C single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001110207] Chr12:51026305 [GRCh38]
Chr12:51420088 [GRCh37]
Chr12:12q13.12
benign
NM_000617.3(SLC11A2):c.-96C>T single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001110956] Chr12:51026367 [GRCh38]
Chr12:51420150 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*1795G>A single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001112709] Chr12:50986530 [GRCh38]
Chr12:51380313 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.*1739C>T single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001112710] Chr12:50986586 [GRCh38]
Chr12:51380369 [GRCh37]
Chr12:12q13.12
uncertain significance
NM_000617.3(SLC11A2):c.1231C>T (p.Arg411Ter) single nucleotide variant Anemia, hypochromic microcytic, with iron overload 1 [RCV001333538] Chr12:50992306 [GRCh38]
Chr12:51386089 [GRCh37]
Chr12:12q13.12
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:10908 AgrOrtholog
COSMIC SLC11A2 COSMIC
Ensembl Genes ENSG00000110911 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000262052 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000378364 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000442810 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000444542 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000446653 UniProtKB/TrEMBL
  ENSP00000446769 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000446914 ENTREZGENE, UniProtKB/TrEMBL
  ENSP00000446984 UniProtKB/TrEMBL
  ENSP00000447102 UniProtKB/TrEMBL
  ENSP00000447482 UniProtKB/TrEMBL
  ENSP00000448501 UniProtKB/TrEMBL
  ENSP00000449008 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000449200 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000449209 UniProtKB/TrEMBL
  ENSP00000450227 UniProtKB/TrEMBL
  ENSP00000450389 UniProtKB/TrEMBL
  ENSP00000493633 UniProtKB/TrEMBL
  ENSP00000494001 UniProtKB/TrEMBL
  ENSP00000494107 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000494619 UniProtKB/TrEMBL
  ENSP00000494696 UniProtKB/TrEMBL
  ENSP00000494744 UniProtKB/TrEMBL
  ENSP00000505087 UniProtKB/TrEMBL
Ensembl Transcript ENST00000262052 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000394904 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000541174 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000545993 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000546488 UniProtKB/TrEMBL
  ENST00000546636 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000546743 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000547198 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000547510 UniProtKB/TrEMBL
  ENST00000547579 UniProtKB/TrEMBL
  ENST00000547688 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000547732 UniProtKB/TrEMBL
  ENST00000548193 UniProtKB/TrEMBL
  ENST00000549625 UniProtKB/TrEMBL
  ENST00000550714 UniProtKB/TrEMBL
  ENST00000551215 UniProtKB/TrEMBL
  ENST00000642227 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000643884 UniProtKB/TrEMBL
  ENST00000644495 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000646264 UniProtKB/TrEMBL
  ENST00000646740 UniProtKB/TrEMBL
  ENST00000646988 UniProtKB/TrEMBL
  ENST00000681324 UniProtKB/TrEMBL
GTEx ENSG00000110911 GTEx
HGNC ID HGNC:10908 ENTREZGENE
Human Proteome Map SLC11A2 Human Proteome Map
InterPro NRAMP_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:4891 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 4891 ENTREZGENE
OMIM 206100 OMIM
  600523 OMIM
PANTHER PTHR11706 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Nramp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA259 PharmGKB
PRINTS NATRESASSCMP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs nramp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A1E835_HUMAN UniProtKB/TrEMBL
  A0A0H3W5I8_HUMAN UniProtKB/TrEMBL
  A0A0H3W5U4_HUMAN UniProtKB/TrEMBL
  A0A0X8GKR4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8Y4F9_HUMAN UniProtKB/TrEMBL
  A0A2R8Y5L1_HUMAN UniProtKB/TrEMBL
  A0A2R8Y5Q7_HUMAN UniProtKB/TrEMBL
  A0A2R8YD71_HUMAN UniProtKB/TrEMBL
  A0A2R8YDL2_HUMAN UniProtKB/TrEMBL
  A0A7P0T8E3_HUMAN UniProtKB/TrEMBL
  B3KY44_HUMAN UniProtKB/TrEMBL
  F8VR36_HUMAN UniProtKB/TrEMBL
  F8VRL7_HUMAN UniProtKB/TrEMBL
  F8VWB0_HUMAN UniProtKB/TrEMBL
  F8W154_HUMAN UniProtKB/TrEMBL
  F8W1C0_HUMAN UniProtKB/TrEMBL
  F8W1D8_HUMAN UniProtKB/TrEMBL
  F8W1F2_HUMAN UniProtKB/TrEMBL
  F8W1P7_HUMAN UniProtKB/TrEMBL
  H0YIV3_HUMAN UniProtKB/TrEMBL
  NRAM2_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary B3KT08 UniProtKB/Swiss-Prot
  B4DK84 UniProtKB/Swiss-Prot
  F5H741 UniProtKB/Swiss-Prot
  O43288 UniProtKB/Swiss-Prot
  O60932 UniProtKB/Swiss-Prot
  O94801 UniProtKB/Swiss-Prot
  Q498Z5 UniProtKB/Swiss-Prot
  Q8IUD7 UniProtKB/Swiss-Prot
  Q96J35 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-23 SLC11A2  solute carrier family 11 member 2    solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2  Symbol and/or name change 5135510 APPROVED
2013-07-23 SLC11A2  solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2    solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2  Symbol and/or name change 5135510 APPROVED