SLC11A2 (solute carrier family 11 member 2) - Rat Genome Database

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Gene: SLC11A2 (solute carrier family 11 member 2) Sus scrofa
Analyze
Symbol: SLC11A2
Name: solute carrier family 11 member 2
RGD ID: 14055005
Description: ENCODES a protein that exhibits cadmium ion binding (ortholog); cadmium ion transmembrane transporter activity (ortholog); calcium ion transmembrane transporter activity (ortholog); INVOLVED IN cellular response to hypoxia (ortholog); cellular response to iron ion (ortholog); cellular response to oxidative stress (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; iron uptake pathway; ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); anemia (ortholog); brain ischemia (ortholog); FOUND IN apical part of cell (ortholog); cell surface (ortholog); late endosome (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: divalent metal transporter 1; DMT1; natural resistance-associated macrophage protein 2; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position: No map positions available.




Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:28534724   PMID:30032202  


Genomics

Comparative Map Data
SLC11A2
(Sus scrofa - pig)		 No map positions available.
SLC11A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381250,952,263 - 51,028,886 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1250,979,401 - 51,028,566 (-)Ensemblhg38GRCh38
GRCh371251,373,190 - 51,422,669 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361249,666,044 - 49,706,409 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341249,666,043 - 49,706,409NCBI
Celera1250,175,791 - 50,224,278 (-)NCBICelera
Cytogenetic Map12q13.12NCBI
HuRef1248,405,542 - 48,453,948 (-)NCBIHuRef
CHM1_11251,339,878 - 51,388,358 (-)NCBICHM1_1
T2T-CHM13v2.01250,915,621 - 50,992,224 (-)NCBIT2T-CHM13v2.0
Slc11a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915100,285,779 - 100,322,090 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15100,285,779 - 100,322,953 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3815100,387,898 - 100,424,209 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15100,387,898 - 100,425,072 (-)Ensemblmm10GRCm38
MGSCv3715100,218,329 - 100,253,486 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3615100,215,932 - 100,251,017 (-)NCBIMGSCv36mm8
Celera15102,539,003 - 102,574,160 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1556.29NCBI
Slc11a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87133,381,878 - 133,429,921 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7133,381,878 - 133,418,941 (-)EnsemblGRCr8
mRatBN7.27131,503,076 - 131,540,246 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7131,503,081 - 131,540,145 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7133,305,973 - 133,342,852 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07135,531,551 - 135,568,430 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07135,444,055 - 135,481,251 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07142,025,812 - 142,062,892 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7142,025,815 - 142,063,212 (-)Ensemblrn6Rnor6.0
Rnor_5.07139,833,529 - 139,870,819 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47139,094,505 - 139,127,427 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7127,985,198 - 128,017,825 (-)NCBICelera
RGSC_v3.17139,170,941 - 139,203,864 (-)NCBI
Cytogenetic Map7q36NCBI
SLC11A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21043,160,550 - 43,207,136 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11243,157,312 - 43,212,817 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01237,726,158 - 37,774,554 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11238,629,576 - 38,677,377 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1238,629,686 - 38,677,377 (+)EnsemblpanPan2panpan1.1
SLC11A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1273,788,785 - 3,823,852 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl273,787,855 - 3,822,672 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2742,433,184 - 42,468,214 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0273,835,730 - 3,870,717 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl273,835,750 - 3,870,711 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1273,802,428 - 3,837,405 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0273,789,782 - 3,824,709 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02742,829,654 - 42,864,682 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Slc11a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494564,541,218 - 64,575,407 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365128,586,262 - 8,623,597 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365128,590,302 - 8,622,121 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC11A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11147,190,138 - 47,238,543 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1147,197,168 - 47,235,130 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037198,862,999 - 198,915,680 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc11a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248161,345,006 - 1,384,299 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248161,345,020 - 1,389,615 (+)NCBIHetGla 1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence



Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000034039 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015016112 UniProtKB/TrEMBL
  ENSSSCG00030040137 UniProtKB/TrEMBL
  ENSSSCG00035077453 UniProtKB/TrEMBL
  ENSSSCG00045005312 UniProtKB/TrEMBL
  ENSSSCG00050042232 UniProtKB/TrEMBL
  ENSSSCG00055018875 UniProtKB/TrEMBL
  ENSSSCG00065040872 UniProtKB/TrEMBL
  ENSSSCG00070030410 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000042375 ENTREZGENE
  ENSSSCT00000042375.3 UniProtKB/TrEMBL
  ENSSSCT00000043790.3 UniProtKB/TrEMBL
  ENSSSCT00000047355 ENTREZGENE
  ENSSSCT00000047355.3 UniProtKB/TrEMBL
  ENSSSCT00000050069.3 UniProtKB/TrEMBL
  ENSSSCT00000059222.2 UniProtKB/TrEMBL
  ENSSSCT00000080368 ENTREZGENE
  ENSSSCT00000080368.2 UniProtKB/TrEMBL
  ENSSSCT00000080393.1 UniProtKB/TrEMBL
  ENSSSCT00015022937.1 UniProtKB/TrEMBL
  ENSSSCT00030056307.1 UniProtKB/TrEMBL
  ENSSSCT00030056326.1 UniProtKB/TrEMBL
  ENSSSCT00035106878.1 UniProtKB/TrEMBL
  ENSSSCT00035106910.1 UniProtKB/TrEMBL
  ENSSSCT00035107314.1 UniProtKB/TrEMBL
  ENSSSCT00045008821.1 UniProtKB/TrEMBL
  ENSSSCT00045008825.1 UniProtKB/TrEMBL
  ENSSSCT00045008832.1 UniProtKB/TrEMBL
  ENSSSCT00045008837.1 UniProtKB/TrEMBL
  ENSSSCT00045008844.1 UniProtKB/TrEMBL
  ENSSSCT00050057427.1 UniProtKB/TrEMBL
  ENSSSCT00050057444.1 UniProtKB/TrEMBL
  ENSSSCT00055037807.1 UniProtKB/TrEMBL
  ENSSSCT00055038357.1 UniProtKB/TrEMBL
  ENSSSCT00055038534.1 UniProtKB/TrEMBL
  ENSSSCT00055038827.1 UniProtKB/TrEMBL
  ENSSSCT00065056004.1 UniProtKB/TrEMBL
  ENSSSCT00065056066.1 UniProtKB/TrEMBL
  ENSSSCT00070061195.1 UniProtKB/TrEMBL
  ENSSSCT00070061197.1 UniProtKB/TrEMBL
  ENSSSCT00070061204.1 UniProtKB/TrEMBL
  ENSSSCT00070061209.1 UniProtKB/TrEMBL
  ENSSSCT00070061216.1 UniProtKB/TrEMBL
  ENSSSCT00070061222.1 UniProtKB/TrEMBL
InterPro NRAMP_fam UniProtKB/TrEMBL
KEGG Report ssc:733595 UniProtKB/TrEMBL
NCBI Gene SLC11A2 ENTREZGENE
PANTHER NATURAL RESISTANCE-ASSOCIATED MACROPHAGE PROTEIN 2 UniProtKB/TrEMBL
  PTHR11706 UniProtKB/TrEMBL
Pfam Nramp UniProtKB/TrEMBL
PRINTS NATRESASSCMP UniProtKB/TrEMBL
UniProt A0A0B8S011 ENTREZGENE
  A0A286ZVW1_PIG UniProtKB/TrEMBL
  A0A286ZYV6_PIG UniProtKB/TrEMBL
  A0A287BIX1_PIG UniProtKB/TrEMBL
  A0A287BKX2_PIG UniProtKB/TrEMBL
  A0A287BLE8_PIG UniProtKB/TrEMBL
  A0A480HUS9 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1W6W9_PIG UniProtKB/TrEMBL
  A0A4X1WCA8_PIG UniProtKB/TrEMBL
  A0A4X1WCC2_PIG UniProtKB/TrEMBL
  A0A4X1WDL4_PIG UniProtKB/TrEMBL
  A0A5G2QCN0_PIG UniProtKB/TrEMBL
  A0A5G2QXA1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0ILB9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0IPA1_PIG UniProtKB/TrEMBL
  A0A8D0WPW7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0WWI2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1D5S2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1D5S6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1GL51 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1GL63_PIG UniProtKB/TrEMBL
  A0A8D1GL83_PIG UniProtKB/TrEMBL
  A0A8D1KQR9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1YU94 ENTREZGENE, UniProtKB/TrEMBL
  B2ZDZ3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:92920 ENTREZGENE