Gene: Col2a1 (collagen type II alpha 1 chain) Rattus norvegicus
Symbol: Col2a1
Name: collagen type II alpha 1 chain
Description: ENCODES a protein that exhibits identical protein binding (ortholog); MHC class II protein binding (ortholog); platelet-derived growth factor binding (ortholog); INVOLVED IN cartilage development; cartilage development involved in endochondral bone morphogenesis; cellular response to insulin-like growth factor stimulus; PARTICIPATES IN syndecan signaling pathway; cell-extracellular matrix signaling pathway; Entamoeba histolyca infection pathway; ASSOCIATED WITH chondrodystrophy; ASSOCIATED WITH Bronchial Fistula; Femur Head Necrosis; Fetal Growth Retardation; FOUND IN cytoplasm; basement membrane (ortholog); collagen trimer (ortholog); INTERACTS WITH (R)-carnitine; (R)-mevalonic acid; (R)-pantothenic acid
Type: protein-coding
Also known as: alpha-1 type II collagen; CG2A1A; collagen alpha-1(II) chain; collagen type II (Col2A1) gene, enhancer region; collagen, type II, alpha 1; COLLII; Procollagen II alpha 1; procollagen, type II, alpha 1
Homo sapiens (human) : COL2A1 (collagen type II alpha 1 chain)  HGNC  Alliance
Mus musculus (house mouse) : Col2a1 (collagen, type II, alpha 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Col2a1 (collagen type II alpha 1 chain)
Canis lupus familiaris (dog) : COL2A1 (collagen type II alpha 1 chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Col2a1 (collagen type II alpha 1 chain)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07139,454,945 - 139,484,403 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07139,646,698 - 139,675,832 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47136,679,219 - 136,707,976 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17136,755,655 - 136,784,413 (-)NCBI
Celera7125,589,749 - 125,618,504 (-)NCBICelera
Cytogenetic Map7q36NCBI
RH 3.4 Map71096.2RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Col2a1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2375
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-03-13
Status: ACTIVE