(+)-catechin increases phosphorylation ISO RGD:732757 6480464 Catechin results in increased phosphorylation of PTK2 protein CTD PMID:16038899 (+)-pilocarpine increases phosphorylation ISO RGD:732757 6480464 Pilocarpine results in increased phosphorylation of PTK2 protein CTD PMID:10537051 (+)-pilocarpine multiple interactions ISO RGD:732757 6480464 [Pilocarpine co-treated with wortmannin] results in increased phosphorylation of PTK2 protein CTD PMID:10537051 (-)-epigallocatechin 3-gallate decreases phosphorylation ISO RGD:732758 6480464 epigallocatechin gallate results in decreased phosphorylation of PTK2 protein CTD PMID:11746506 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:732757 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of PTK2 mRNA CTD PMID:22079256 (S)-nicotine multiple interactions ISO RGD:732757 6480464 [Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of PTK2 protein CTD PMID:30259641 1,2-dimethylhydrazine multiple interactions ISO RGD:732758 6480464 Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in increased expression of PTK2 mRNA] CTD PMID:22206623 1,2-dimethylhydrazine increases expression ISO RGD:732758 6480464 1, 2-Dimethylhydrazine results in increased expression of PTK2 mRNA CTD PMID:22206623 1,4-dithiothreitol multiple interactions ISO RGD:732757 6480464 Dithiothreitol affects the reaction [4-cresol sulfate affects the localization of PTK2 protein] CTD PMID:31873818 1,8-cineole multiple interactions ISO RGD:732758 6480464 Eucalyptol inhibits the reaction [Glucose results in decreased expression of PTK2 protein], Eucalyptol inhibits the reaction [LEP gene mutant form results in decreased expression of PTK2 protein] CTD PMID:31483951 1-octadec-9-enoylglycero-3-phosphate increases phosphorylation ISO RGD:732758 6480464 lysophosphatidic acid results in increased phosphorylation of PTK2 protein CTD PMID:11792571 1-octadec-9-enoylglycero-3-phosphate multiple interactions ISO RGD:732757 6480464 [wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein more ... CTD PMID:10537051 1-octadec-9-enoylglycero-3-phosphate multiple interactions EXP 6480464 [wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein, KNG1 protein inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein] CTD PMID:10537051 1-octadec-9-enoylglycero-3-phosphate increases phosphorylation ISO RGD:732757 6480464 lysophosphatidic acid results in increased phosphorylation of PTK2 protein CTD PMID:10537051 1-octadec-9-enoylglycero-3-phosphate increases phosphorylation EXP 6480464 lysophosphatidic acid results in increased phosphorylation of PTK2 protein CTD PMID:10537051 17alpha-ethynylestradiol affects expression ISO RGD:732758 6480464 Ethinyl Estradiol affects the expression of PTK2 mRNA CTD PMID:17555576 17alpha-ethynylestradiol multiple interactions ISO RGD:732758 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PTK2 mRNA CTD PMID:17942748 17beta-estradiol increases phosphorylation ISO RGD:732757 6480464 Estradiol results in increased phosphorylation of PTK2 protein CTD PMID:12421874 17beta-estradiol increases degradation ISO RGD:732757 6480464 Estradiol results in increased degradation of PTK2 protein CTD PMID:24440569 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:732758 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PTK2 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of PTK2 mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:732758 6480464 Tetrachlorodibenzodioxin affects the expression of PTK2 mRNA CTD PMID:21570461 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of PTK2 mRNA CTD PMID:21346803 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine multiple interactions EXP 6480464 Puromycin Aminonucleoside results in increased expression of and results in increased phosphorylation of PTK2 protein CTD PMID:14559718 3,4-methylenedioxymethamphetamine increases expression ISO RGD:732758 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of PTK2 mRNA CTD PMID:20188158 3-methylcholanthrene multiple interactions ISO RGD:732757 6480464 alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased phosphorylation of PTK2 protein] CTD PMID:16359657 3-methylcholanthrene decreases phosphorylation ISO RGD:732757 6480464 Methylcholanthrene results in decreased phosphorylation of PTK2 protein CTD PMID:16359657 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1, 2-dithiol-3-thione results in decreased expression of PTK2 mRNA CTD PMID:19162173 4,4'-sulfonyldiphenol decreases methylation ISO RGD:732757 6480464 bis(4-hydroxyphenyl)sulfone results in decreased methylation of PTK2 gene CTD PMID:31601247 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions ISO RGD:732757 6480464 [Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of PTK2 protein CTD PMID:30259641 4-hydroxycoumarin decreases phosphorylation ISO RGD:732758 6480464 4-hydroxycoumarin results in decreased phosphorylation of PTK2 protein CTD PMID:18492274 4-hydroxynon-2-enal decreases expression ISO RGD:732757 6480464 4-hydroxy-2-nonenal results in decreased expression of PTK2 mRNA CTD PMID:12419474 4-tert-Octylphenol increases phosphorylation ISO RGD:732757 6480464 4-tert-octylphenol results in increased phosphorylation of PTK2 protein CTD PMID:32466334 5-fluorouracil decreases response to substance ISO RGD:732757 6480464 PTK2 protein results in decreased susceptibility to Fluorouracil CTD PMID:16179862 5-fluorouracil affects expression ISO RGD:732757 6480464 Fluorouracil affects the expression of PTK2 mRNA CTD PMID:34151400 8-Br-cAMP multiple interactions ISO RGD:732758 6480464 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [HU 211 results in increased phosphorylation of PTK2 protein] CTD PMID:12163181 acrylamide increases phosphorylation ISO RGD:732757 6480464 Acrylamide results in increased phosphorylation of PTK2 protein CTD PMID:11478917 , PMID:18215454 acrylamide decreases phosphorylation ISO RGD:732757 6480464 Acrylamide results in decreased phosphorylation of PTK2 protein CTD PMID:18215454 acrylamide multiple interactions ISO RGD:732757 6480464 2-cyclopentyl-5-(5-isoquinolylsulfonyl)-6-nitro-1H-benzo(D)imidazole inhibits the reaction [Acrylamide results in increased phosphorylation of PTK2 protein] CTD PMID:11478917 actinomycin D decreases expression EXP 6480464 Dactinomycin results in decreased expression of PTK2 protein CTD PMID:15959627 aflatoxin B1 increases methylation ISO RGD:732757 6480464 Aflatoxin B1 results in increased methylation of PTK2 gene CTD PMID:27153756 aflatoxin B1 decreases expression ISO RGD:732757 6480464 Aflatoxin B1 results in decreased expression of PTK2 mRNA CTD PMID:28943387 aldehydo-D-glucose multiple interactions ISO RGD:732758 6480464 Eucalyptol inhibits the reaction [Glucose results in decreased expression of PTK2 protein], Glucose inhibits the reaction [IL1B protein results in increased phosphorylation of PTK2 protein] CTD PMID:30098273 , PMID:31483951 aldehydo-D-glucose decreases expression ISO RGD:732758 6480464 Glucose results in decreased expression of PTK2 protein CTD PMID:31483951 aldehydo-D-glucose decreases expression ISO RGD:732757 6480464 Glucose results in decreased expression of PTK2 mRNA CTD PMID:31655124 all-trans-retinoic acid multiple interactions ISO RGD:732757 6480464 PTK2 protein inhibits the reaction [Tretinoin promotes the reaction [CEBPA protein binds to RB1 protein]] more ... CTD PMID:16226872 all-trans-retinoic acid increases expression ISO RGD:732757 6480464 Tretinoin results in increased expression of PTK2 mRNA CTD PMID:17045167 all-trans-retinoic acid increases cleavage ISO RGD:732757 6480464 Tretinoin results in increased cleavage of PTK2 protein CTD PMID:11369141 all-trans-retinoic acid decreases response to substance ISO RGD:732757 6480464 PTK2 protein results in decreased susceptibility to Tretinoin CTD PMID:16226872 alpha-naphthoflavone multiple interactions ISO RGD:732757 6480464 alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased phosphorylation of PTK2 protein] CTD PMID:16359657 aluminium oxide multiple interactions ISO RGD:732757 6480464 [Aluminum Oxide co-treated with Magnesium] results in increased expression of PTK2 protein CTD PMID:12209937 AM-251 multiple interactions ISO RGD:732757 6480464 [AM 251 co-treated with iodopravadoline] inhibits the reaction [Dronabinol results in increased phosphorylation of PTK2 protein] CTD PMID:31461164 ammonium chloride decreases expression EXP 6480464 Ammonium Chloride results in decreased expression of PTK2 protein CTD PMID:16483693 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PTK2 mRNA CTD PMID:16483693 amosite asbestos increases activity ISO RGD:732758 6480464 Asbestos, Amosite results in increased activity of PTK2 protein CTD PMID:29112861 Anetholtrithion multiple interactions ISO RGD:732757 6480464 Anethole Trithione inhibits the reaction [Reactive Oxygen Species results in increased phosphorylation of PTK2 protein] CTD PMID:11213483 antirheumatic drug increases expression ISO RGD:732757 6480464 Antirheumatic Agents results in increased expression of PTK2 mRNA CTD PMID:24449571 aristolochic acid A decreases expression ISO RGD:732757 6480464 aristolochic acid I results in decreased expression of PTK2 mRNA CTD PMID:33212167 arsane decreases phosphorylation EXP 6480464 Arsenic results in decreased phosphorylation of PTK2 protein CTD PMID:18215454 arsane increases phosphorylation ISO RGD:732757 6480464 Arsenic results in increased phosphorylation of PTK2 protein CTD PMID:18215454 arsane decreases expression ISO RGD:732757 6480464 Arsenic results in decreased expression of PTK2 protein CTD PMID:16420308 arsenic atom increases phosphorylation ISO RGD:732757 6480464 Arsenic results in increased phosphorylation of PTK2 protein CTD PMID:18215454 arsenic atom decreases expression ISO RGD:732757 6480464 Arsenic results in decreased expression of PTK2 protein CTD PMID:16420308 arsenic atom decreases phosphorylation EXP 6480464 Arsenic results in decreased phosphorylation of PTK2 protein CTD PMID:18215454 arsenite(3-) multiple interactions ISO RGD:732757 6480464 arsenite inhibits the reaction [G3BP1 protein binds to PTK2 mRNA] CTD PMID:32406909 atrazine multiple interactions ISO RGD:732757 6480464 Atrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PTK2 protein] CTD PMID:24211529 atrazine affects methylation EXP 6480464 Atrazine affects the methylation of PTK2 gene CTD PMID:35440735 atropine multiple interactions ISO RGD:732757 6480464 Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein]] more ... CTD PMID:10537051 barium(0) increases phosphorylation ISO RGD:732757 6480464 Barium results in increased phosphorylation of PTK2 protein CTD PMID:23804419 benzene decreases expression ISO RGD:732757 6480464 Benzene results in decreased expression of PTK2 mRNA CTD PMID:33064461 benzo[a]pyrene increases expression ISO RGD:732758 6480464 Benzo(a)pyrene results in increased expression of PTK2 mRNA CTD PMID:22228805 benzo[a]pyrene affects methylation ISO RGD:732757 6480464 Benzo(a)pyrene affects the methylation of PTK2 5' UTR, Benzo(a)pyrene affects the methylation of PTK2 intron CTD PMID:27901495 , PMID:30157460 benzo[a]pyrene decreases expression ISO RGD:732757 6480464 Benzo(a)pyrene results in decreased expression of PTK2 mRNA CTD PMID:20064835 more ... benzo[a]pyrene diol epoxide I decreases expression ISO RGD:732757 6480464 7 more ... CTD PMID:19150397 , PMID:28529061 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PTK2 mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO RGD:732757 6480464 [RTKI cpd co-treated with bisphenol A] results in increased phosphorylation of PTK2 protein, GPER1 protein affects the reaction [bisphenol A results in increased phosphorylation of PTK2 protein] CTD PMID:32325111 bisphenol A increases phosphorylation ISO RGD:732757 6480464 bisphenol A results in increased phosphorylation of PTK2 protein CTD PMID:31143956 more ... bisphenol F multiple interactions ISO RGD:732757 6480464 [bisphenol F co-treated with Fulvestrant] results in decreased methylation of PTK2 gene CTD PMID:31601247 blebbistatin decreases phosphorylation ISO RGD:732757 6480464 blebbistatin results in decreased phosphorylation of PTK2 protein CTD PMID:18718759 BQ 123 multiple interactions ISO RGD:732757 6480464 [BQ 788 co-treated with cyclo(Trp-Asp-Pro-Val-Leu)] inhibits the reaction [EDN1 protein results in increased phosphorylation of PTK2 protein] CTD PMID:12875994 bufalin decreases expression ISO RGD:732757 6480464 bufalin results in decreased expression of PTK2 protein CTD PMID:23949904 cadmium atom multiple interactions ISO RGD:732757 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PTK2 mRNA CTD PMID:35301059 cadmium dichloride multiple interactions ISO RGD:732758 6480464 Cadmium Chloride results in decreased expression of and results in increased phosphorylation of PTK2 protein CTD PMID:28830677 cadmium dichloride increases phosphorylation ISO RGD:732757 6480464 Cadmium Chloride results in increased phosphorylation of PTK2 protein CTD PMID:28527916 cadmium dichloride multiple interactions ISO RGD:732757 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PTK2 mRNA more ... CTD PMID:28830677 , PMID:35301059 caffeine affects phosphorylation ISO RGD:732757 6480464 Caffeine affects the phosphorylation of PTK2 protein CTD PMID:35688186 capsaicin multiple interactions ISO RGD:732757 6480464 Capsaicin inhibits the reaction [EGF results in increased phosphorylation of PTK2 protein] CTD PMID:21462327 carbamazepine affects expression ISO RGD:732757 6480464 Carbamazepine affects the expression of PTK2 mRNA CTD PMID:24752500 , PMID:25979313 carbamazepine decreases activity ISO RGD:732757 6480464 Carbamazepine results in decreased activity of PTK2 protein CTD PMID:24352538 carbon nanotube affects expression ISO RGD:732758 6480464 Nanotubes, Carbon affects the expression of PTK2 mRNA CTD PMID:23845593 carbon nanotube increases activity ISO RGD:732758 6480464 Nanotubes, Carbon results in increased activity of PTK2 protein CTD PMID:29112861 carbon nanotube decreases expression ISO RGD:732758 6480464 Nanotubes more ... CTD PMID:25554681 carvone decreases phosphorylation ISO RGD:732757 6480464 carvone results in decreased phosphorylation of PTK2 protein CTD PMID:37059214 casticin decreases expression ISO RGD:732758 6480464 casticin results in decreased expression of PTK2 protein CTD PMID:28444820 CGP 52608 multiple interactions ISO RGD:732757 6480464 CGP 52608 promotes the reaction [RORA protein binds to PTK2 gene] CTD PMID:28238834 chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of PTK2 mRNA CTD PMID:20691718 chromium(6+) multiple interactions ISO RGD:732757 6480464 Luteolin inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of PTK2 protein] CTD PMID:25448439 chromium(6+) increases phosphorylation ISO RGD:732757 6480464 chromium hexavalent ion results in increased phosphorylation of PTK2 protein CTD PMID:25448439 chrysin decreases phosphorylation ISO RGD:732757 6480464 chrysin results in decreased phosphorylation of PTK2 protein CTD PMID:30578657 cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of PTK2 protein modified form CTD PMID:23628706 cisplatin decreases expression ISO RGD:732757 6480464 Cisplatin results in decreased expression of PTK2 mRNA, Cisplatin results in decreased expression of PTK2 protein CTD PMID:16391810 more ... cisplatin decreases expression ISO RGD:732758 6480464 Cisplatin results in decreased expression of PTK2 protein modified form CTD PMID:23628706 clozapine increases expression ISO RGD:732757 6480464 Clozapine results in increased expression of PTK2 protein CTD PMID:34122009 cocaine decreases expression ISO RGD:732757 6480464 Cocaine results in decreased expression of PTK2 mRNA CTD PMID:12629581 cocaine decreases phosphorylation ISO RGD:732758 6480464 Cocaine results in decreased phosphorylation of PTK2 protein CTD PMID:27506785 copper atom multiple interactions EXP 6480464 [Copper deficiency co-treated with tetrathiomolybdate] results in decreased phosphorylation of PTK2 protein CTD PMID:22276220 copper atom multiple interactions ISO RGD:732757 6480464 [Chelating Agents binds to Copper] which results in increased expression of PTK2 mRNA CTD PMID:30911355 copper(0) multiple interactions EXP 6480464 [Copper deficiency co-treated with tetrathiomolybdate] results in decreased phosphorylation of PTK2 protein CTD PMID:22276220 copper(0) multiple interactions ISO RGD:732757 6480464 [Chelating Agents binds to Copper] which results in increased expression of PTK2 mRNA CTD PMID:30911355 crocidolite asbestos decreases expression ISO RGD:732758 6480464 Asbestos, Crocidolite results in decreased expression of PTK2 mRNA CTD PMID:29279043 cyclosporin A decreases methylation ISO RGD:732757 6480464 Cyclosporine results in decreased methylation of PTK2 promoter CTD PMID:27989131 D-glucose multiple interactions ISO RGD:732758 6480464 Eucalyptol inhibits the reaction [Glucose results in decreased expression of PTK2 protein], Glucose inhibits the reaction [IL1B protein results in increased phosphorylation of PTK2 protein] CTD PMID:30098273 , PMID:31483951 D-glucose decreases expression ISO RGD:732758 6480464 Glucose results in decreased expression of PTK2 protein CTD PMID:31483951 D-glucose decreases expression ISO RGD:732757 6480464 Glucose results in decreased expression of PTK2 mRNA CTD PMID:31655124 D-mannitol multiple interactions ISO RGD:732757 6480464 benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [Mannitol results in decreased phosphorylation of and results in increased degradation of PTK2 protein], Mannitol results in decreased phosphorylation of and results in increased degradation of PTK2 protein CTD PMID:12011046 daidzein increases phosphorylation ISO RGD:732757 6480464 daidzein results in increased phosphorylation of PTK2 protein CTD PMID:12421874 deguelin decreases expression ISO RGD:732757 6480464 deguelin results in decreased expression of PTK2 protein CTD PMID:25322282 deguelin increases expression ISO RGD:732757 6480464 deguelin results in increased expression of PTK2 mRNA CTD PMID:33512557 diallyl trisulfide decreases expression ISO RGD:732757 6480464 diallyl trisulfide results in decreased expression of PTK2 protein, diallyl trisulfide results in decreased expression of PTK2 protein modified form CTD PMID:28741790 dibenzo[a,l]pyrene decreases expression ISO RGD:732757 6480464 dibenzo(a, l)pyrene results in decreased expression of PTK2 mRNA CTD PMID:16269432 diclofenac affects expression ISO RGD:732757 6480464 Diclofenac affects the expression of PTK2 mRNA CTD PMID:24752500 Dictamnine decreases phosphorylation ISO RGD:732757 6480464 dictamnine results in decreased phosphorylation of PTK2 protein CTD PMID:34861243 dioscin multiple interactions ISO RGD:732757 6480464 dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of PTK2 protein] CTD PMID:25111127 disodium selenite multiple interactions ISO RGD:732757 6480464 Sodium Selenite results in increased phosphorylation of and results in increased activity of PTK2 protein CTD PMID:12896980 dorsomorphin multiple interactions ISO RGD:732757 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxazosin decreases expression ISO RGD:732757 6480464 Doxazosin results in decreased expression of PTK2 protein CTD PMID:15221243 doxazosin increases cleavage ISO RGD:732758 6480464 Doxazosin results in increased cleavage of PTK2 protein CTD PMID:22845314 doxorubicin multiple interactions ISO RGD:732757 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [PTK2 protein promotes the reaction [Doxorubicin results in increased phosphorylation of AKT1 protein]], PTK2 protein promotes the reaction [Doxorubicin results in increased phosphorylation of AKT1 protein] CTD PMID:16168102 doxorubicin decreases phosphorylation EXP 6480464 Doxorubicin results in decreased phosphorylation of PTK2 protein CTD PMID:16825486 doxorubicin affects cleavage ISO RGD:732757 6480464 Doxorubicin affects the cleavage of PTK2 protein CTD PMID:15870702 emodin affects expression EXP 6480464 Emodin affects the expression of PTK2 protein CTD PMID:19549930 endosulfan increases phosphorylation ISO RGD:732757 6480464 Endosulfan results in increased phosphorylation of PTK2 protein CTD PMID:22677888 , PMID:32044604 endosulfan decreases expression ISO RGD:732757 6480464 Endosulfan results in decreased expression of PTK2 protein, Endosulfan results in decreased expression of PTK2 protein modified form CTD PMID:28108160 ethanol multiple interactions ISO RGD:732757 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of PTK2 mRNA CTD PMID:29432896 ethanol affects splicing ISO RGD:732758 6480464 Ethanol affects the splicing of PTK2 mRNA CTD PMID:30319688 ethyl methanesulfonate decreases expression ISO RGD:732757 6480464 Ethyl Methanesulfonate results in decreased expression of PTK2 mRNA CTD PMID:23649840 everolimus decreases expression ISO RGD:732757 6480464 Everolimus results in decreased expression of PTK2 protein modified form CTD PMID:28258630 fenthion decreases expression ISO RGD:732758 6480464 Fenthion results in decreased expression of PTK2 mRNA CTD PMID:34813904 flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of PTK2 mRNA CTD PMID:18035473 flavonol decreases phosphorylation ISO RGD:732757 6480464 3-hydroxyflavone results in decreased phosphorylation of PTK2 protein CTD PMID:27600294 flubendazole decreases expression ISO RGD:732757 6480464 flubendazole results in decreased expression of PTK2 protein CTD PMID:30075109 flutamide increases expression EXP 6480464 Flutamide results in increased expression of PTK2 mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:732758 6480464 Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in increased expression of PTK2 mRNA] CTD PMID:22206623 formaldehyde decreases expression ISO RGD:732757 6480464 Formaldehyde results in decreased expression of PTK2 mRNA CTD PMID:23649840 fulvestrant increases degradation ISO RGD:732757 6480464 fulvestrant results in increased degradation of PTK2 protein CTD PMID:24440569 fulvestrant multiple interactions ISO RGD:732757 6480464 [bisphenol F co-treated with Fulvestrant] results in decreased methylation of PTK2 gene CTD PMID:31601247 gadolinium trichloride increases activity ISO RGD:732757 6480464 gadolinium chloride results in increased activity of PTK2 CTD PMID:19184457 Garcinol decreases phosphorylation ISO RGD:732757 6480464 garcinol results in decreased phosphorylation of PTK2 protein CTD PMID:16052481 geldanamycin increases degradation ISO RGD:732757 6480464 geldanamycin results in increased degradation of PTK2 protein CTD PMID:9973544 geldanamycin decreases phosphorylation ISO RGD:732757 6480464 geldanamycin results in decreased phosphorylation of PTK2 protein CTD PMID:12811834 geldanamycin increases degradation ISO RGD:732758 6480464 geldanamycin results in increased degradation of PTK2 protein CTD PMID:9973544 gemcitabine decreases response to substance ISO RGD:732757 6480464 PTK2 protein results in decreased susceptibility to Gemcitabine CTD PMID:14623342 genistein increases phosphorylation ISO RGD:732757 6480464 Genistein results in increased phosphorylation of PTK2 protein CTD PMID:12421874 Geraniin decreases phosphorylation ISO RGD:732757 6480464 Geraniin results in decreased phosphorylation of PTK2 protein CTD PMID:31184425 glucose decreases expression ISO RGD:732757 6480464 Glucose results in decreased expression of PTK2 mRNA CTD PMID:31655124 glucose decreases expression ISO RGD:732758 6480464 Glucose results in decreased expression of PTK2 protein CTD PMID:31483951 glucose multiple interactions ISO RGD:732758 6480464 Eucalyptol inhibits the reaction [Glucose results in decreased expression of PTK2 protein], Glucose inhibits the reaction [IL1B protein results in increased phosphorylation of PTK2 protein] CTD PMID:30098273 , PMID:31483951 halothane decreases phosphorylation ISO RGD:732757 6480464 Halothane results in decreased phosphorylation of PTK2 protein CTD PMID:18215454 heparin decreases phosphorylation ISO RGD:732758 6480464 Heparin results in decreased phosphorylation of PTK2 protein CTD PMID:18674534 hyaluronic acid multiple interactions EXP 6480464 Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of PTK2 protein] CTD PMID:23178681 hydrogen peroxide affects expression ISO RGD:732757 6480464 Hydrogen Peroxide affects the expression of PTK2 mRNA CTD PMID:20044591 hydrogen peroxide multiple interactions EXP 6480464 Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of PTK2 protein] CTD PMID:23178681 hydrogen peroxide decreases phosphorylation EXP 6480464 Hydrogen Peroxide results in decreased phosphorylation of PTK2 protein CTD PMID:23178681 hydrogen peroxide increases cleavage ISO RGD:732757 6480464 Hydrogen Peroxide results in increased cleavage of PTK2 protein CTD PMID:17888894 hydrogen peroxide multiple interactions ISO RGD:732757 6480464 benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Hydrogen Peroxide results in increased cleavage of PTK2 protein] CTD PMID:17888894 indometacin affects localization ISO RGD:732757 6480464 Indomethacin affects the localization of PTK2 protein CTD PMID:12037131 indometacin decreases phosphorylation ISO RGD:732757 6480464 Indomethacin results in decreased phosphorylation of PTK2 protein CTD PMID:12037131 indometacin multiple interactions ISO RGD:732757 6480464 Indomethacin inhibits the reaction [EGF protein affects the localization of PTK2 protein], Indomethacin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:12037131 irinotecan decreases expression ISO RGD:732757 6480464 Irinotecan analog results in decreased expression of PTK2 mRNA CTD PMID:18927307 ivermectin decreases expression ISO RGD:732757 6480464 Ivermectin results in decreased expression of PTK2 protein CTD PMID:32959892 ketamine decreases expression EXP 6480464 Ketamine results in decreased expression of PTK2 mRNA CTD PMID:20080153 L-1,4-dithiothreitol multiple interactions ISO RGD:732757 6480464 Dithiothreitol affects the reaction [4-cresol sulfate affects the localization of PTK2 protein] CTD PMID:31873818 L-ascorbic acid decreases expression EXP 6480464 Ascorbic Acid results in decreased expression of PTK2 mRNA CTD PMID:15372504 lead(0) decreases phosphorylation EXP 6480464 Lead results in decreased phosphorylation of PTK2 protein CTD PMID:18215454 lead(0) affects splicing ISO RGD:732757 6480464 Lead affects the splicing of PTK2 mRNA CTD PMID:28903495 lipopolysaccharide increases phosphorylation ISO RGD:732758 6480464 Lipopolysaccharides results in increased phosphorylation of PTK2 protein CTD PMID:21125213 lithocholic acid multiple interactions ISO RGD:732757 6480464 Lithocholic Acid results in decreased phosphorylation of and results in decreased activity of PTK2 protein CTD PMID:21224350 luteolin multiple interactions ISO RGD:732757 6480464 EGF protein inhibits the reaction [Luteolin results in decreased phosphorylation of PTK2 protein] more ... CTD PMID:15135307 , PMID:25448439 luteolin decreases phosphorylation ISO RGD:732757 6480464 Luteolin results in decreased phosphorylation of PTK2 protein CTD PMID:15135307 LY294002 multiple interactions ISO RGD:732757 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein], 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [PTK2 protein promotes the reaction [Doxorubicin results in increased phosphorylation of AKT1 protein]] CTD PMID:16168102 , PMID:26109002 magnesium atom multiple interactions ISO RGD:732757 6480464 [Aluminum Oxide co-treated with Magnesium] results in increased expression of PTK2 protein CTD PMID:12209937 mebendazole decreases expression ISO RGD:732757 6480464 Mebendazole results in decreased expression of PTK2 protein CTD PMID:30075109 methidathion decreases expression ISO RGD:732758 6480464 methidathion results in decreased expression of PTK2 mRNA CTD PMID:34813904 methyl methanesulfonate decreases expression ISO RGD:732757 6480464 Methyl Methanesulfonate results in decreased expression of PTK2 mRNA CTD PMID:23649840 methylisothiazolinone decreases phosphorylation EXP 6480464 2-methyl-4-isothiazolin-3-one results in decreased phosphorylation of PTK2 protein CTD PMID:18215454 methylmercury chloride decreases expression ISO RGD:732757 6480464 methylmercuric chloride results in decreased expression of PTK2 mRNA CTD PMID:26272509 , PMID:28001369 microcystin-LR decreases expression EXP 6480464 cyanoginosin LR results in decreased expression of PTK2 mRNA CTD PMID:36657700 ML-7 decreases phosphorylation ISO RGD:732757 6480464 ML 7 results in decreased phosphorylation of PTK2 protein CTD PMID:18718759 N-acetyl-L-cysteine multiple interactions ISO RGD:732757 6480464 Acetylcysteine inhibits the reaction [[[Thimerosal results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP3 protein] which results in increased cleavage of PTK2 protein] CTD PMID:17888894 nickel dichloride increases expression ISO RGD:732758 6480464 nickel chloride results in increased expression of PTK2 mRNA CTD PMID:12839937 nickel dichloride multiple interactions ISO RGD:732758 6480464 HIF1A affects the reaction [nickel chloride results in increased expression of PTK2 mRNA] CTD PMID:12729255 nicotine multiple interactions ISO RGD:732757 6480464 [Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of PTK2 protein CTD PMID:30259641 nitric oxide decreases expression ISO RGD:732758 6480464 Nitric Oxide deficiency results in decreased expression of PTK2 mRNA CTD PMID:15878706 ochratoxin A increases expression ISO RGD:732757 6480464 ochratoxin A metabolite results in increased expression of PTK2 mRNA, ochratoxin A results in increased expression of PTK2 mRNA CTD PMID:26314263 Octicizer decreases phosphorylation ISO RGD:732757 6480464 2-ethylhexyldiphenylphosphate results in decreased phosphorylation of PTK2 protein CTD PMID:37027338 Ophiopogonin D multiple interactions ISO RGD:732757 6480464 ITGB1 protein inhibits the reaction [ophiopogonin D inhibits the reaction [TGFB1 protein results in increased phosphorylation of PTK2 protein]], ophiopogonin D inhibits the reaction [TGFB1 protein results in increased phosphorylation of PTK2 protein] CTD PMID:32818624 oxotremorine M multiple interactions ISO RGD:732757 6480464 [oxophenylarsine co-treated with oxotremorine M] results in increased phosphorylation of PTK2 protein more ... CTD PMID:10537051 oxotremorine M increases phosphorylation ISO RGD:732757 6480464 oxotremorine M results in increased phosphorylation of PTK2 protein CTD PMID:10537051 ozone decreases expression EXP 6480464 Ozone results in decreased expression of PTK2 mRNA CTD PMID:16330353 p-menthan-3-ol decreases expression ISO RGD:732757 6480464 Menthol results in decreased expression of PTK2 mRNA CTD PMID:26760959 p-tert-Amylphenol increases phosphorylation ISO RGD:732757 6480464 4-tert-octylphenol results in increased phosphorylation of PTK2 protein CTD PMID:32466334 paracetamol decreases expression ISO RGD:732757 6480464 Acetaminophen results in decreased expression of PTK2 mRNA CTD PMID:22230336 pentachlorophenol increases expression ISO RGD:732758 6480464 Pentachlorophenol results in increased expression of PTK2 mRNA CTD PMID:23892564 perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of PTK2 mRNA CTD PMID:20136073 perfluorooctane-1-sulfonic acid decreases response to substance ISO RGD:732757 6480464 PTK2 protein mutant form results in decreased susceptibility to perfluorooctane sulfonic acid CTD PMID:29150642 perfluorooctane-1-sulfonic acid increases expression ISO RGD:732758 6480464 perfluorooctane sulfonic acid results in increased expression of PTK2 protein CTD PMID:26178269 phenethyl caffeate decreases phosphorylation ISO RGD:732757 6480464 caffeic acid phenethyl ester results in decreased phosphorylation of PTK2 protein CTD PMID:10741720 phenylarsine oxide multiple interactions ISO RGD:732757 6480464 [oxophenylarsine co-treated with oxotremorine M] results in increased phosphorylation of PTK2 protein more ... CTD PMID:10537051 , PMID:10569804 phenylarsine oxide increases phosphorylation ISO RGD:732757 6480464 oxophenylarsine results in increased phosphorylation of PTK2 protein CTD PMID:10537051 phenylmercury acetate decreases expression ISO RGD:732757 6480464 Phenylmercuric Acetate results in decreased expression of PTK2 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:732757 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PTK2 mRNA CTD PMID:27188386 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:732757 6480464 [oxophenylarsine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PTK2 protein more ... CTD PMID:10537051 more ... phorbol 13-acetate 12-myristate increases phosphorylation ISO RGD:732757 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of PTK2 protein CTD PMID:10537051 more ... phosgene affects expression ISO RGD:732758 6480464 Phosgene affects the expression of PTK2 mRNA CTD PMID:16300373 picoxystrobin increases expression ISO RGD:732757 6480464 picoxystrobin results in increased expression of PTK2 mRNA CTD PMID:33512557 pinosylvin decreases expression ISO RGD:732757 6480464 pinosylvin results in decreased expression of PTK2 protein modified form CTD PMID:23333577 pirinixic acid increases expression ISO RGD:732758 6480464 pirinixic acid results in increased expression of PTK2 mRNA CTD PMID:18301758 platycodin D decreases phosphorylation ISO RGD:732757 6480464 platycodin D results in decreased phosphorylation of PTK2 protein CTD PMID:25250884 poly(vinylpyrrolidone) multiple interactions ISO RGD:732758 6480464 [Silver Compounds co-treated with Povidone] results in increased activity of PTK2 protein CTD PMID:21729742 potassium chromate multiple interactions ISO RGD:732757 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of PTK2 mRNA CTD PMID:22079256 potassium chromate decreases expression ISO RGD:732757 6480464 potassium chromate(VI) results in decreased expression of PTK2 mRNA CTD PMID:22079256 potassium iodide decreases expression EXP 6480464 Potassium Iodide results in decreased expression of PTK2 protein, Potassium Iodide results in decreased expression of PTK2 protein modified form CTD PMID:32593569 progesterone decreases expression EXP 6480464 Progesterone results in decreased expression of PTK2 mRNA CTD PMID:20726854 protein kinase inhibitor multiple interactions ISO RGD:732758 6480464 [Protein Kinase Inhibitors results in decreased activity of PTK2 protein] inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA] CTD PMID:30098273 protein kinase inhibitor decreases activity ISO RGD:732758 6480464 Protein Kinase Inhibitors results in decreased activity of PTK2 protein CTD PMID:30098273 quercetin multiple interactions ISO RGD:732757 6480464 EGF protein inhibits the reaction [Quercetin results in decreased phosphorylation of PTK2 protein] more ... CTD PMID:15135307 , PMID:25971889 quercetin decreases expression ISO RGD:732757 6480464 Quercetin results in decreased expression of PTK2 protein CTD PMID:23645742 quercetin decreases phosphorylation ISO RGD:732757 6480464 Quercetin results in decreased phosphorylation of PTK2 protein CTD PMID:15135307 , PMID:25971889 quercetin 3-O-beta-D-glucofuranoside multiple interactions ISO RGD:732757 6480464 isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 quercetin 3-O-beta-D-glucopyranoside multiple interactions ISO RGD:732757 6480464 isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 quinacrine decreases phosphorylation ISO RGD:732757 6480464 Quinacrine results in decreased phosphorylation of PTK2 protein CTD PMID:35724837 reactive oxygen species multiple interactions ISO RGD:732757 6480464 [[Thimerosal results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP3 protein] which results in increased cleavage of PTK2 protein more ... CTD PMID:11213483 , PMID:17888894 reactive oxygen species increases phosphorylation ISO RGD:732757 6480464 Reactive Oxygen Species results in increased phosphorylation of PTK2 protein CTD PMID:11213483 resveratrol increases phosphorylation ISO RGD:732757 6480464 resveratrol results in increased phosphorylation of PTK2 protein CTD PMID:12421874 resveratrol decreases expression ISO RGD:732758 6480464 resveratrol results in decreased expression of PTK2 protein modified form CTD PMID:24659233 resveratrol decreases phosphorylation ISO RGD:732757 6480464 resveratrol results in decreased phosphorylation of PTK2 protein CTD PMID:12421874 , PMID:25605016 resveratrol affects localization ISO RGD:732757 6480464 resveratrol affects the localization of PTK2 protein CTD PMID:21467134 resveratrol multiple interactions ISO RGD:732757 6480464 resveratrol promotes the reaction [[ITGAV protein binds to ITGB3 protein] which affects the localization of PTK2 protein] CTD PMID:21467134 resveratrol decreases expression ISO RGD:732757 6480464 resveratrol results in decreased expression of PTK2 mRNA, resveratrol results in decreased expression of PTK2 protein CTD PMID:18089832 rotenone increases expression ISO RGD:732757 6480464 Rotenone results in increased expression of PTK2 mRNA CTD PMID:33512557 S-butyl-DL-homocysteine (S,R)-sulfoximine increases expression ISO RGD:732758 6480464 Buthionine Sulfoximine results in increased expression of PTK2 mRNA CTD PMID:15878706 Salinomycin decreases phosphorylation ISO RGD:732757 6480464 salinomycin results in decreased phosphorylation of PTK2 protein CTD PMID:28395993 Salvianolic acid A decreases phosphorylation ISO RGD:732757 6480464 salvianolic acid A results in decreased phosphorylation of PTK2 protein CTD PMID:29385302 SB 431542 multiple interactions ISO RGD:732757 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 silver atom increases phosphorylation EXP 6480464 Silver results in increased phosphorylation of PTK2 protein CTD PMID:11341783 silver(0) increases phosphorylation EXP 6480464 Silver results in increased phosphorylation of PTK2 protein CTD PMID:11341783 simvastatin decreases activity ISO RGD:732757 6480464 Simvastatin results in decreased activity of PTK2 protein CTD PMID:17428261 sirolimus decreases phosphorylation ISO RGD:732758 6480464 Sirolimus results in decreased phosphorylation of PTK2 protein CTD PMID:19922502 sodium arsenite increases expression ISO RGD:732757 6480464 sodium arsenite results in increased expression of PTK2 mRNA CTD PMID:12016162 sodium arsenite decreases phosphorylation EXP 6480464 sodium arsenite results in decreased phosphorylation of PTK2 protein CTD PMID:15537746 sodium chloride increases expression ISO RGD:732757 6480464 Sodium Chloride results in increased expression of PTK2 mRNA CTD PMID:23634900 sulindac sulfide decreases phosphorylation ISO RGD:732757 6480464 sulindac sulfide results in decreased phosphorylation of PTK2 protein CTD PMID:10741720 tamoxifen affects expression ISO RGD:732758 6480464 Tamoxifen affects the expression of PTK2 mRNA CTD PMID:17555576 terbinafine decreases phosphorylation ISO RGD:732757 6480464 terbinafine results in decreased phosphorylation of PTK2 protein CTD PMID:17172416 tert-butyl hydroperoxide decreases expression ISO RGD:732757 6480464 tert-Butylhydroperoxide results in decreased expression of PTK2 mRNA CTD PMID:15336504 testosterone increases phosphorylation ISO RGD:732757 6480464 Testosterone results in increased phosphorylation of PTK2 protein CTD PMID:16038899 testosterone multiple interactions ISO RGD:732757 6480464 wortmannin inhibits the reaction [Testosterone results in increased phosphorylation of PTK2 protein] CTD PMID:16038899 tetrachloromethane increases expression ISO RGD:732758 6480464 Carbon Tetrachloride results in increased expression of PTK2 mRNA CTD PMID:31919559 tetrathiomolybdate(2-) multiple interactions EXP 6480464 [Copper deficiency co-treated with tetrathiomolybdate] results in decreased phosphorylation of PTK2 protein CTD PMID:22276220 thapsigargin decreases expression ISO RGD:732758 6480464 Thapsigargin results in decreased expression of PTK2 protein CTD PMID:24648495 thimerosal increases response to substance ISO RGD:732757 6480464 PTK2 protein results in increased susceptibility to Thimerosal CTD PMID:17888894 thimerosal multiple interactions ISO RGD:732757 6480464 [[Thimerosal results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP3 protein] which results in increased cleavage of PTK2 protein more ... CTD PMID:17888894 trans-pinosylvin decreases expression ISO RGD:732757 6480464 pinosylvin results in decreased expression of PTK2 protein modified form CTD PMID:23333577 trichostatin A decreases expression ISO RGD:732757 6480464 trichostatin A results in decreased expression of PTK2 mRNA CTD PMID:24935251 Triptolide decreases expression ISO RGD:732758 6480464 triptolide results in decreased expression of PTK2 mRNA, triptolide results in decreased expression of PTK2 protein CTD PMID:26420756 Triptolide increases expression EXP 6480464 triptolide results in increased expression of PTK2 protein CTD PMID:32519852 Triptolide increases expression ISO RGD:732758 6480464 triptolide results in increased expression of PTK2 protein CTD PMID:26990902 tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate multiple interactions ISO RGD:732757 6480464 Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[Wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein]] more ... CTD PMID:10537051 Tryptanthrine decreases phosphorylation ISO RGD:732757 6480464 tryptanthrine results in decreased phosphorylation of PTK2 protein CTD PMID:26341616 tyrphostin AG 1478 multiple interactions ISO RGD:732757 6480464 [RTKI cpd co-treated with bisphenol A] results in increased phosphorylation of PTK2 protein CTD PMID:32325111 uranium atom affects expression ISO RGD:732757 6480464 Uranium affects the expression of PTK2 mRNA CTD PMID:15672453 valproic acid affects expression ISO RGD:732757 6480464 Valproic Acid affects the expression of PTK2 mRNA CTD PMID:25979313 valproic acid multiple interactions ISO RGD:732757 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PTK2 mRNA CTD PMID:27188386 valproic acid decreases expression ISO RGD:732757 6480464 Valproic Acid results in decreased expression of PTK2 mRNA CTD PMID:23179753 more ... wortmannin multiple interactions ISO RGD:732757 6480464 [Pilocarpine co-treated with wortmannin] results in increased phosphorylation of PTK2 protein more ... CTD PMID:10537051 , PMID:16038899 wortmannin multiple interactions EXP 6480464 [wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein more ... CTD PMID:10537051 zearalenone decreases expression ISO RGD:732758 6480464 Zearalenone results in decreased expression of PTK2 protein CTD PMID:36288102 zearalenone decreases expression EXP 6480464 Zearalenone results in decreased expression of PTK2 protein CTD PMID:36288102 zoledronic acid decreases phosphorylation ISO RGD:732757 6480464 zoledronic acid results in decreased phosphorylation of PTK2 protein CTD PMID:12933798 zoledronic acid increases expression ISO RGD:732757 6480464 zoledronic acid results in increased expression of PTK2 mRNA CTD PMID:20977926
