Gene: Ptk2 (protein tyrosine kinase 2) Rattus norvegicus
Symbol: Ptk2
Name: protein tyrosine kinase 2
Description: ENCODES a protein that exhibits identical protein binding; integrin binding; phosphatase binding; INVOLVED IN cellular chloride ion homeostasis; fat cell differentiation; JNK cascade; PARTICIPATES IN long term potentiation; integrin mediated signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH Carcinoma, Hepatocellular; Hypertension; Hypertrophy, Left Ventricular; FOUND IN apical plasma membrane; basolateral plasma membrane; dendritic spine; INTERACTS WITH 1-octadec-9-enoylglycero-3-phosphate; 2,4-dinitrotoluene; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FADK 1; FAK; focal adhesion kinase; focal adhesion kinase 1; focal adhesion kinase-related nonkinase; FRNK; p125FAK; pp125FAK; Protein tyrosine kinase; protein-tyrosine kinase 2; PTK2 protein tyrosine kinase 2
Homo sapiens (human) : PTK2 (protein tyrosine kinase 2)  HGNC  AGR
Mus musculus (house mouse) : Ptk2 (PTK2 protein tyrosine kinase 2)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Ptk2 (protein tyrosine kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PTK2 (protein tyrosine kinase 2)
Canis lupus familiaris (dog) : PTK2 (protein tyrosine kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptk2 (protein tyrosine kinase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07114,436,419 - 114,611,317 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07114,371,979 - 114,525,553 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47110,933,298 - 111,084,554 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17110,967,527 - 111,118,784 (-)NCBI
Celera7101,534,957 - 101,690,471 (-)NCBICelera
Cytogenetic Map7q34NCBI
RH 3.4 Map7725.6RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Ptk2
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3443
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-11-14
Status: ACTIVE