Ptk2 (protein tyrosine kinase 2) - Rat Genome Database

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Gene: Ptk2 (protein tyrosine kinase 2) Rattus norvegicus
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Symbol: Ptk2
Name: protein tyrosine kinase 2
RGD ID: 3443
Description: Enables several functions, including identical protein binding activity; integrin binding activity; and phosphatidylinositol 3-kinase binding activity. Involved in several processes, including cellular chloride ion homeostasis; positive regulation of cell population proliferation; and regulation of cell migration. Located in several cellular components, including basolateral plasma membrane; focal adhesion; and nuclear lumen. Is active in glutamatergic synapse. Used to study hepatocellular carcinoma; hypertension; and nephritis. Biomarker of hypertension; ischemia; and uremia. Human ortholog(s) of this gene implicated in leiomyoma; lung small cell carcinoma; and pulmonary hypertension. Orthologous to human PTK2 (protein tyrosine kinase 2); PARTICIPATES IN long term potentiation; integrin mediated signaling pathway; vascular endothelial growth factor signaling pathway; INTERACTS WITH 1-octadec-9-enoylglycero-3-phosphate; 2,4-dinitrotoluene; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FADK 1; FAK; focal adhesion kinase; focal adhesion kinase 1; focal adhesion kinase-related nonkinase; FRNK; p125FAK; pp125FAK; Protein tyrosine kinase; protein-tyrosine kinase 2; PTK2 protein tyrosine kinase 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27105,126,725 - 105,331,848 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl7105,126,728 - 105,331,783 (-)Ensembl
Rnor_6.07114,436,419 - 114,611,317 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7114,437,361 - 114,590,119 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07114,371,979 - 114,525,553 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47110,933,298 - 111,084,554 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17110,967,527 - 111,118,784 (-)NCBI
Celera7101,534,957 - 101,690,471 (-)NCBICelera
RH 3.4 Map7725.6RGD
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(+)-pilocarpine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
1,4-dithiothreitol  (ISO)
1,8-cineole  (ISO)
1-octadec-9-enoylglycero-3-phosphate  (EXP,ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-methylcholanthrene  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-hydroxycoumarin  (ISO)
4-hydroxynon-2-enal  (ISO)
5-fluorouracil  (ISO)
8-Br-cAMP  (ISO)
acrylamide  (ISO)
actinomycin D  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-naphthoflavone  (ISO)
aluminium oxide  (ISO)
AM-251  (ISO)
ammonium chloride  (EXP)
amosite asbestos  (ISO)
Anetholtrithion  (ISO)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
atrazine  (ISO)
atropine  (ISO)
barium(0)  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
blebbistatin  (ISO)
BQ 123  (ISO)
bufalin  (ISO)
cadmium dichloride  (ISO)
capsaicin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
casticin  (ISO)
chlorpyrifos  (EXP)
chromium(6+)  (ISO)
chrysin  (ISO)
cisplatin  (EXP,ISO)
cocaine  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
D-mannitol  (ISO)
daidzein  (ISO)
Deguelin  (ISO)
diallyl trisulfide  (ISO)
dibenzo[a,l]pyrene  (ISO)
diclofenac  (ISO)
dioscin  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxazosin  (ISO)
doxorubicin  (EXP,ISO)
emodin  (EXP)
endosulfan  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
everolimus  (ISO)
flavonoids  (EXP)
flavonol  (ISO)
flubendazole  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
gadolinium trichloride  (ISO)
Garcinol  (ISO)
geldanamycin  (ISO)
gemcitabine  (ISO)
genistein  (ISO)
Geraniin  (ISO)
glucose  (ISO)
halothane  (ISO)
heparin  (ISO)
hyaluronic acid  (EXP)
hydrogen peroxide  (EXP,ISO)
indometacin  (ISO)
irinotecan  (ISO)
ivermectin  (ISO)
ketamine  (EXP)
L-1,4-dithiothreitol  (ISO)
L-ascorbic acid  (EXP)
lead(0)  (EXP,ISO)
lead(2+)  (EXP,ISO)
lipopolysaccharide  (ISO)
lithocholic acid  (ISO)
luteolin  (ISO)
LY294002  (ISO)
magnesium atom  (ISO)
mebendazole  (ISO)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (EXP)
methylmercury chloride  (ISO)
ML-7  (ISO)
N-acetyl-L-cysteine  (ISO)
nickel dichloride  (ISO)
nicotine  (ISO)
nitric oxide  (ISO)
ochratoxin A  (ISO)
oxotremorine M  (ISO)
ozone  (EXP)
p-menthan-3-ol  (ISO)
paracetamol  (ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
phenethyl caffeate  (ISO)
phenylarsine oxide  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phosgene  (ISO)
picoxystrobin  (ISO)
pinosylvin  (ISO)
pirinixic acid  (ISO)
platycodin D  (ISO)
poly(vinylpyrrolidone)  (ISO)
potassium chromate  (ISO)
potassium iodide  (EXP)
progesterone  (EXP)
protein kinase inhibitor  (ISO)
quercetin  (ISO)
quercetin 3-O-beta-D-glucofuranoside  (ISO)
quercetin 3-O-beta-D-glucopyranoside  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
Salinomycin  (ISO)
Salvianolic acid A  (ISO)
SB 431542  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
simvastatin  (ISO)
sirolimus  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sulindac sulfide  (ISO)
tamoxifen  (ISO)
terbinafine  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetrathiomolybdate(2-)  (EXP)
thapsigargin  (ISO)
thimerosal  (ISO)
trans-pinosylvin  (ISO)
trichostatin A  (ISO)
Triptolide  (EXP,ISO)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (ISO)
tyrphostin AG 1478  (ISO)
uranium atom  (ISO)
valproic acid  (ISO)
wortmannin  (EXP,ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
angiogenesis  (IBA,IEA,ISO)
blood vessel development  (ISO)
cell differentiation  (IBA)
cell migration  (IEA,ISO)
cellular chloride ion homeostasis  (IMP)
cellular response to transforming growth factor beta stimulus  (ISO)
central nervous system neuron axonogenesis  (ISO)
endothelial cell migration  (ISO)
ephrin receptor signaling pathway  (IEA,ISO,ISS)
epidermal growth factor receptor signaling pathway  (IBA)
extracellular matrix organization  (ISO)
fat cell differentiation  (IEP)
growth hormone receptor signaling pathway  (IEA,ISO)
innate immune response  (IBA)
integrin-mediated signaling pathway  (IDA,IEA,ISO,ISS)
JNK cascade  (IMP)
MAPK cascade  (IMP)
microtubule cytoskeleton organization  (ISO)
negative regulation of anoikis  (IEA,ISO)
negative regulation of apoptotic process  (IMP,ISO)
negative regulation of autophagy  (ISO)
negative regulation of axonogenesis  (ISO)
negative regulation of cell migration  (IMP)
negative regulation of cell-cell adhesion  (IEA,ISO)
negative regulation of organ growth  (ISO)
negative regulation of synapse assembly  (ISO)
neuron migration  (ISO)
nuclear migration  (ISO)
peptidyl-tyrosine autophosphorylation  (ISO)
peptidyl-tyrosine phosphorylation  (IEA,ISO,ISS)
positive regulation of cardiac muscle hypertrophy  (ISO)
positive regulation of cell adhesion  (IMP)
positive regulation of cell growth  (IMP)
positive regulation of cell migration  (IMP,ISO)
positive regulation of cell population proliferation  (ISO,ISS)
positive regulation of fibroblast migration  (IEA,ISO)
positive regulation of glial cell proliferation  (IMP)
positive regulation of macrophage chemotaxis  (IEA,ISO)
positive regulation of macrophage proliferation  (IEA,ISO)
positive regulation of phagocytosis  (IMP)
positive regulation of phosphatidylinositol 3-kinase signaling  (IEA,ISO,ISS)
positive regulation of protein kinase activity  (IEA,ISO,ISS)
positive regulation of protein kinase B signaling  (IEA,ISO,ISS)
positive regulation of protein phosphorylation  (ISO,ISS)
positive regulation of smooth muscle cell migration  (IMP)
positive regulation of smooth muscle cell proliferation  (IMP)
positive regulation of synaptic transmission  (IMP)
positive regulation of ubiquitin-dependent protein catabolic process  (ISO,ISS)
positive regulation of wound healing  (IEA,ISO)
protein autophosphorylation  (IEA,ISO,ISS)
regulation of cell adhesion  (IBA)
regulation of cell adhesion mediated by integrin  (IEA,ISO,ISS)
regulation of cell population proliferation  (ISO,ISS)
regulation of cell shape  (IEA,ISO,ISS)
regulation of epithelial cell migration  (IEA,ISO)
regulation of focal adhesion assembly  (IEA,ISO)
regulation of osteoblast differentiation  (IEA,ISO,ISS)
regulation of protein phosphorylation  (ISO)
regulation of substrate adhesion-dependent cell spreading  (IEA,ISO)
response to arsenic-containing substance  (IEP)
response to estradiol  (IEP)
response to glucose  (IEP)
response to mechanical stimulus  (IEP)
response to organic cyclic compound  (IEP)
response to organic substance  (IEP)
response to organonitrogen compound  (IEP)
response to xenobiotic stimulus  (IEP)
signal complex assembly  (IEA)
transforming growth factor beta receptor signaling pathway  (IEA,ISO)
transmembrane receptor protein tyrosine kinase signaling pathway  (IBA)
vasculogenesis  (ISO)
vasodilation  (IMP)

Cellular Component

References

References - curated
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Additional References at PubMed
PMID:2132399   PMID:7529876   PMID:7673154   PMID:8889548   PMID:9038154   PMID:10655584   PMID:10699171   PMID:10742111   PMID:10925297   PMID:11331870   PMID:11513739   PMID:11784865  
PMID:12133485   PMID:12235133   PMID:12391143   PMID:12556538   PMID:12595342   PMID:12651850   PMID:12829427   PMID:12932810   PMID:12941275   PMID:12967635   PMID:14551814   PMID:14642275  
PMID:14676198   PMID:14715243   PMID:14963000   PMID:15077193   PMID:15096502   PMID:15166238   PMID:15172101   PMID:15174102   PMID:15206825   PMID:15287896   PMID:15378065   PMID:15494733  
PMID:15576648   PMID:15591141   PMID:15640164   PMID:15681841   PMID:15728191   PMID:15855171   PMID:15914540   PMID:15923313   PMID:15967814   PMID:16010975   PMID:16095866   PMID:16298995  
PMID:16374517   PMID:16405917   PMID:16803572   PMID:16927379   PMID:17012369   PMID:17088251   PMID:17136425   PMID:17179255   PMID:17240116   PMID:17417603   PMID:17549512   PMID:17583725  
PMID:17868879   PMID:17877062   PMID:17986008   PMID:17999938   PMID:18206965   PMID:18297732   PMID:18539755   PMID:18662671   PMID:18757826   PMID:18773890   PMID:19016591   PMID:19116150  
PMID:19118217   PMID:19141060   PMID:19172391   PMID:19213829   PMID:19224536   PMID:19340459   PMID:19361463   PMID:19372463   PMID:19470773   PMID:19470782   PMID:19484266   PMID:19553453  
PMID:19793767   PMID:19880666   PMID:19912685   PMID:19913511   PMID:20142421   PMID:20705914   PMID:21180139   PMID:21246051   PMID:21412826   PMID:21562308   PMID:21569089   PMID:21637765  
PMID:21660950   PMID:21703394   PMID:21829547   PMID:21852560   PMID:21921830   PMID:21937583   PMID:22120166   PMID:22227249   PMID:22293597   PMID:22402981   PMID:22778269   PMID:22797892  
PMID:22914642   PMID:23073828   PMID:23168795   PMID:23301073   PMID:23463649   PMID:23574715   PMID:23755149   PMID:23880313   PMID:23904105   PMID:24036928   PMID:24056044   PMID:24169556  
PMID:24703506   PMID:24742749   PMID:24930861   PMID:25280940   PMID:25300309   PMID:25319025   PMID:25708150   PMID:25820249   PMID:25898827   PMID:26294392   PMID:26481700   PMID:26742689  
PMID:26754294   PMID:26763945   PMID:26835911   PMID:26846226   PMID:26884826   PMID:27212270   PMID:27427476   PMID:27428469   PMID:27704688   PMID:27827993   PMID:27994061   PMID:28360109  
PMID:28445805   PMID:28759036   PMID:28851074   PMID:30138615   PMID:30154481   PMID:30187999   PMID:31630787   PMID:32352989   PMID:32592615   PMID:32707896   PMID:33051346   PMID:33434537  


Genomics

Comparative Map Data
Ptk2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27105,126,725 - 105,331,848 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl7105,126,728 - 105,331,783 (-)Ensembl
Rnor_6.07114,436,419 - 114,611,317 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7114,437,361 - 114,590,119 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07114,371,979 - 114,525,553 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47110,933,298 - 111,084,554 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17110,967,527 - 111,118,784 (-)NCBI
Celera7101,534,957 - 101,690,471 (-)NCBICelera
RH 3.4 Map7725.6RGD
Cytogenetic Map7q34NCBI
PTK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl8140,657,900 - 141,002,216 (-)EnsemblGRCh38hg38GRCh38
GRCh388140,657,900 - 141,002,079 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378141,667,999 - 142,012,178 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368141,737,683 - 142,080,514 (-)NCBINCBI36hg18NCBI36
Build 348141,737,682 - 142,080,514NCBI
Celera8137,836,859 - 138,179,410 (-)NCBI
Cytogenetic Map8q24.3NCBI
HuRef8136,979,065 - 137,322,195 (-)NCBIHuRef
CHM1_18141,708,729 - 142,051,666 (-)NCBICHM1_1
Ptk2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391573,076,951 - 73,297,192 (-)NCBIGRCm39mm39
GRCm39 Ensembl1573,076,951 - 73,295,129 (-)Ensembl
GRCm381573,205,102 - 73,423,820 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1573,205,102 - 73,423,280 (-)EnsemblGRCm38mm10GRCm38
MGSCv371573,035,535 - 73,253,621 (-)NCBIGRCm37mm9NCBIm37
MGSCv361573,032,362 - 73,221,980 (-)NCBImm8
Celera1574,705,367 - 74,923,905 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1533.94NCBI
Ptk2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546114,337,914 - 14,556,931 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546114,337,914 - 14,622,779 (-)NCBIChiLan1.0ChiLan1.0
PTK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.18140,412,773 - 140,743,129 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8140,412,773 - 140,684,898 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v08137,330,777 - 137,677,306 (-)NCBIMhudiblu_PPA_v0panPan3
PTK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11335,302,439 - 35,541,336 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1335,303,380 - 35,541,294 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1335,161,620 - 35,427,478 (-)NCBI
ROS_Cfam_1.01335,687,298 - 35,953,785 (-)NCBI
UMICH_Zoey_3.11335,407,367 - 35,673,847 (-)NCBI
UNSW_CanFamBas_1.01335,497,341 - 35,763,586 (-)NCBI
UU_Cfam_GSD_1.01335,917,116 - 36,183,296 (-)NCBI
Ptk2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053032,953,767 - 3,152,431 (+)NCBI
SpeTri2.0NW_00493647010,379,855 - 10,578,531 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl42,656,613 - 2,896,060 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.142,656,606 - 2,896,060 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PTK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18134,897,511 - 135,246,300 (-)NCBI
Vero_WHO_p1.0NW_0236660394,888,238 - 5,242,010 (+)NCBI
Ptk2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473515,356,911 - 15,713,219 (+)NCBI

Position Markers
RH139110  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27105,165,886 - 105,166,016 (+)MAPPERmRatBN7.2
Rnor_6.07114,479,057 - 114,479,186NCBIRnor6.0
Rnor_5.07114,414,617 - 114,414,746UniSTSRnor5.0
RGSC_v3.47110,972,806 - 110,972,935UniSTSRGSC3.4
Celera7101,574,059 - 101,574,188UniSTS
RH 3.4 Map7722.7UniSTS
Cytogenetic Map7q34UniSTS
Ptk2  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.47110,933,361 - 110,933,513UniSTSRGSC3.4
RGSC_v3.47110,933,379 - 110,933,531UniSTSRGSC3.4
Celera7101,535,033 - 101,535,185UniSTS
Celera7101,535,051 - 101,535,203UniSTS
RH128225  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27105,126,949 - 105,127,162 (+)MAPPERmRatBN7.2
Rnor_6.07114,436,644 - 114,436,856NCBIRnor6.0
Rnor_5.07114,372,204 - 114,372,416UniSTSRnor5.0
RGSC_v3.47110,933,510 - 110,933,722UniSTSRGSC3.4
Celera7101,535,182 - 101,535,394UniSTS
RH 3.4 Map7721.9UniSTS
Cytogenetic Map7q34UniSTS
RH130965  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27105,127,140 - 105,127,327 (+)MAPPERmRatBN7.2
Rnor_6.07114,436,835 - 114,437,021NCBIRnor6.0
Rnor_5.07114,372,395 - 114,372,581UniSTSRnor5.0
RGSC_v3.47110,933,701 - 110,933,887UniSTSRGSC3.4
Celera7101,535,373 - 101,535,559UniSTS
RH 3.4 Map7722.6UniSTS
Cytogenetic Map7q34UniSTS
RH94436  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map7725.6UniSTS
Cytogenetic Map7q34UniSTS
RH138184  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27105,230,462 - 105,230,635 (+)MAPPERmRatBN7.2
Rnor_6.07114,543,607 - 114,543,779NCBIRnor6.0
Rnor_5.07114,478,952 - 114,479,124UniSTSRnor5.0
RGSC_v3.47111,037,952 - 111,038,124UniSTSRGSC3.4
Celera7101,638,612 - 101,638,784UniSTS
RH 3.4 Map7722.8UniSTS
Cytogenetic Map7q34UniSTS
UniSTS:143067  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27105,126,912 - 105,127,571 (+)MAPPERmRatBN7.2
Rnor_6.07114,436,607 - 114,437,265NCBIRnor6.0
Rnor_5.07114,372,167 - 114,372,825UniSTSRnor5.0
RGSC_v3.47110,933,473 - 110,934,131UniSTSRGSC3.4
Celera7101,535,145 - 101,535,803UniSTS
Cytogenetic Map7q34UniSTS
PMC84535P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27105,161,304 - 105,162,290 (+)MAPPERmRatBN7.2
Rnor_6.07114,474,476 - 114,475,460NCBIRnor6.0
Rnor_5.07114,410,036 - 114,411,020UniSTSRnor5.0
RGSC_v3.47110,968,225 - 110,969,209UniSTSRGSC3.4
Celera7101,569,478 - 101,570,462UniSTS
Cytogenetic Map7q34UniSTS
PMC84535P3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27105,161,342 - 105,162,120 (+)MAPPERmRatBN7.2
Rnor_6.07114,474,514 - 114,475,290NCBIRnor6.0
Rnor_5.07114,410,074 - 114,410,850UniSTSRnor5.0
RGSC_v3.47110,968,263 - 110,969,039UniSTSRGSC3.4
Celera7101,569,516 - 101,570,292UniSTS
Cytogenetic Map7q34UniSTS
Ptk2  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.07114,372,073 - 114,372,225UniSTSRnor5.0
RGSC_v3.47110,933,379 - 110,933,531UniSTSRGSC3.4
Celera7101,535,051 - 101,535,203UniSTS
Cytogenetic Map7q34UniSTS
Ptk2  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.07114,372,055 - 114,372,207UniSTSRnor5.0
RGSC_v3.47110,933,361 - 110,933,513UniSTSRGSC3.4
Celera7101,535,033 - 101,535,185UniSTS
Cytogenetic Map7q34UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)761074194106074194Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)780221299109401111Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)793595647106839474Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:293
Count of miRNA genes:179
Interacting mature miRNAs:199
Transcripts:ENSRNOT00000011219
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 42 55 40 18 40 8 11 74 35 41 11 8
Low 1 2 1 1 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_013081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005486549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005486550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF020777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF020779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI717382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA508631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA511845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB713440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EV773243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U43940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U43941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U43942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000011219   ⟹   ENSRNOP00000011219
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7105,126,956 - 105,331,763 (-)Ensembl
Rnor_6.0 Ensembl7114,437,361 - 114,573,900 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000079599   ⟹   ENSRNOP00000075518
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7105,126,728 - 105,283,089 (-)Ensembl
Rnor_6.0 Ensembl7114,440,949 - 114,590,119 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000095017   ⟹   ENSRNOP00000085395
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7105,126,728 - 105,283,089 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000101944   ⟹   ENSRNOP00000089674
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7105,126,956 - 105,331,763 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000109226   ⟹   ENSRNOP00000080431
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7105,126,956 - 105,331,763 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110466   ⟹   ENSRNOP00000093819
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7105,243,450 - 105,331,783 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000112145   ⟹   ENSRNOP00000095122
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7105,126,728 - 105,283,089 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000113790   ⟹   ENSRNOP00000092163
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7105,126,956 - 105,331,763 (-)Ensembl
RefSeq Acc Id: NM_013081   ⟹   NP_037213
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,126,725 - 105,283,089 (-)NCBI
Rnor_6.07114,436,419 - 114,590,208 (-)NCBI
Rnor_5.07114,371,979 - 114,525,553 (-)NCBI
RGSC_v3.47110,933,298 - 111,084,554 (-)RGD
Celera7101,534,957 - 101,690,471 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039078471   ⟹   XP_038934399
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,126,725 - 105,331,809 (-)NCBI
RefSeq Acc Id: XM_039078472   ⟹   XP_038934400
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,126,725 - 105,331,511 (-)NCBI
RefSeq Acc Id: XM_039078473   ⟹   XP_038934401
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,126,725 - 105,283,003 (-)NCBI
RefSeq Acc Id: XM_039078474   ⟹   XP_038934402
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,126,725 - 105,283,003 (-)NCBI
RefSeq Acc Id: XM_039078475   ⟹   XP_038934403
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,126,725 - 105,283,003 (-)NCBI
RefSeq Acc Id: XM_039078476   ⟹   XP_038934404
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,126,725 - 105,283,003 (-)NCBI
RefSeq Acc Id: XM_039078477   ⟹   XP_038934405
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,126,725 - 105,283,003 (-)NCBI
RefSeq Acc Id: XM_039078478   ⟹   XP_038934406
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,126,725 - 105,283,003 (-)NCBI
RefSeq Acc Id: XM_039078479   ⟹   XP_038934407
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,126,725 - 105,283,003 (-)NCBI
RefSeq Acc Id: XM_039078480   ⟹   XP_038934408
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,126,725 - 105,283,003 (-)NCBI
RefSeq Acc Id: XM_039078482   ⟹   XP_038934410
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,126,725 - 105,283,003 (-)NCBI
RefSeq Acc Id: XM_039078483   ⟹   XP_038934411
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,126,725 - 105,331,809 (-)NCBI
RefSeq Acc Id: XM_039078484   ⟹   XP_038934412
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,126,725 - 105,331,510 (-)NCBI
RefSeq Acc Id: XM_039078485   ⟹   XP_038934413
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,126,725 - 105,331,809 (-)NCBI
RefSeq Acc Id: XM_039078486   ⟹   XP_038934414
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,126,725 - 105,294,588 (-)NCBI
RefSeq Acc Id: XM_039078487   ⟹   XP_038934415
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,126,725 - 105,331,809 (-)NCBI
RefSeq Acc Id: XM_039078488   ⟹   XP_038934416
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,126,725 - 105,331,848 (-)NCBI
RefSeq Acc Id: XM_039078489   ⟹   XP_038934417
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,155,582 - 105,331,809 (-)NCBI
RefSeq Acc Id: XM_039078490   ⟹   XP_038934418
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,126,725 - 105,200,152 (-)NCBI
RefSeq Acc Id: XM_039078491   ⟹   XP_038934419
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,126,725 - 105,200,151 (-)NCBI
RefSeq Acc Id: XR_005486549
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,126,725 - 105,331,809 (-)NCBI
RefSeq Acc Id: XR_005486550
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27105,161,026 - 105,331,809 (-)NCBI
Protein Sequences
Protein RefSeqs NP_037213 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934399 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934400 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934401 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934402 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934403 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934404 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934405 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934406 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934407 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934408 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934410 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934411 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934412 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934413 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934414 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934415 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934416 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934417 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934418 (Get FASTA)   NCBI Sequence Viewer  
  XP_038934419 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA86278 (Get FASTA)   NCBI Sequence Viewer  
  AAA86279 (Get FASTA)   NCBI Sequence Viewer  
  AAA86280 (Get FASTA)   NCBI Sequence Viewer  
  AAB72203 (Get FASTA)   NCBI Sequence Viewer  
  EDM16117 (Get FASTA)   NCBI Sequence Viewer  
  EDM16118 (Get FASTA)   NCBI Sequence Viewer  
  EDM16119 (Get FASTA)   NCBI Sequence Viewer  
  O35346 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_037213   ⟸   NM_013081
- UniProtKB: O35346 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000075518   ⟸   ENSRNOT00000079599
RefSeq Acc Id: ENSRNOP00000011219   ⟸   ENSRNOT00000011219
RefSeq Acc Id: XP_038934416   ⟸   XM_039078488
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038934415   ⟸   XM_039078487
- Peptide Label: isoform X12
RefSeq Acc Id: XP_038934411   ⟸   XM_039078483
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038934399   ⟸   XM_039078471
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038934413   ⟸   XM_039078485
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038934400   ⟸   XM_039078472
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038934412   ⟸   XM_039078484
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038934414   ⟸   XM_039078486
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038934410   ⟸   XM_039078482
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038934406   ⟸   XM_039078478
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038934408   ⟸   XM_039078480
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038934407   ⟸   XM_039078479
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038934405   ⟸   XM_039078477
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038934404   ⟸   XM_039078476
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038934403   ⟸   XM_039078475
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038934402   ⟸   XM_039078474
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038934401   ⟸   XM_039078473
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038934418   ⟸   XM_039078490
- Peptide Label: isoform X14
RefSeq Acc Id: XP_038934419   ⟸   XM_039078491
- Peptide Label: isoform X15
RefSeq Acc Id: XP_038934417   ⟸   XM_039078489
- Peptide Label: isoform X13
RefSeq Acc Id: ENSRNOP00000089674   ⟸   ENSRNOT00000101944
RefSeq Acc Id: ENSRNOP00000095122   ⟸   ENSRNOT00000112145
RefSeq Acc Id: ENSRNOP00000080431   ⟸   ENSRNOT00000109226
RefSeq Acc Id: ENSRNOP00000085395   ⟸   ENSRNOT00000095017
RefSeq Acc Id: ENSRNOP00000093819   ⟸   ENSRNOT00000110466
RefSeq Acc Id: ENSRNOP00000092163   ⟸   ENSRNOT00000113790
Protein Domains
FERM   Protein kinase

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN-Lx/CubMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BUF/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
DA/OlaHsd (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
F344/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FXLE16/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/FarMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
HXB10/IpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEXF10A/StmMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
M520/NRrrcMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MWF/Hsd (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/OlalpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/RijCrl (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3443 AgrOrtholog
Ensembl Genes ENSRNOG00000007916 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000011219 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000075518 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011219 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000079599 UniProtKB/TrEMBL
Gene3D-CATH 1.20.80.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Band_41_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FADK_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FAK1/PYK2_FERM_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM/acyl-CoA-bd_prot_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_central UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Focal_adhe_kin_target_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Focal_adhesion_kin_target_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25614 UniProtKB/Swiss-Prot
NCBI Gene 25614 ENTREZGENE
Pfam FERM_M UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_N_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Focal_AT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase_Tyr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ptk2 PhenoGen
PRINTS TYRKINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE FERM_2 UniProtKB/Swiss-Prot
  FERM_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART B41 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TyrKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47031 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54236 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF68993 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2KAT5_RAT UniProtKB/TrEMBL
  FAK1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q62900 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-28 Ptk2  protein tyrosine kinase 2  Ptk2  PTK2 protein tyrosine kinase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Ptk2  PTK2 protein tyrosine kinase 2    protein tyrosine kinase 2  Name updated 1299863 APPROVED
2002-06-10 Ptk2  Protein tyrosine kinase      Symbol and Name status set to approved 70586 APPROVED