Mir33 (microRNA 33) - Rat Genome Database

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Gene: Mir33 (microRNA 33) Rattus norvegicus
Analyze
Symbol: Mir33
Name: microRNA 33
RGD ID: 2325408
Description: Predicted to enable mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Predicted to be involved in apolipoprotein A-I-mediated signaling pathway; negative regulation of biosynthetic process; and negative regulation of transport. Predicted to act upstream of or within cholesterol homeostasis and post-transcriptional gene silencing. Orthologous to human MIR33A (microRNA 33a); INTERACTS WITH 2,5-hexanedione; aflatoxin B1; aristolochic acid A.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: rno-mir-33
RGD Orthologs
Human
Mouse
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87115,593,952 - 115,594,020 (+)NCBIGRCr8
mRatBN7.27113,713,855 - 113,713,923 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7113,713,855 - 113,713,923 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7115,469,859 - 115,469,927 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07117,693,366 - 117,693,434 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07117,662,807 - 117,662,875 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07123,431,612 - 123,431,680 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7123,431,612 - 123,431,680 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07123,415,303 - 123,415,371 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera7110,029,025 - 110,029,093 (+)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16381832   PMID:16766679   PMID:17604727   PMID:20403161   PMID:20466882   PMID:23922812   PMID:25769350   PMID:26068915   PMID:27041227   PMID:27956176   PMID:28137944   PMID:31468622  
PMID:32455724   PMID:32505219   PMID:34152551   PMID:34183444   PMID:35608068   PMID:36354186  


Genomics

Comparative Map Data
Mir33
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87115,593,952 - 115,594,020 (+)NCBIGRCr8
mRatBN7.27113,713,855 - 113,713,923 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7113,713,855 - 113,713,923 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7115,469,859 - 115,469,927 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07117,693,366 - 117,693,434 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07117,662,807 - 117,662,875 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07123,431,612 - 123,431,680 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7123,431,612 - 123,431,680 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07123,415,303 - 123,415,371 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera7110,029,025 - 110,029,093 (+)NCBICelera
Cytogenetic Map7q34NCBI
MIR33A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382241,900,944 - 41,901,012 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2241,900,944 - 41,901,012 (+)EnsemblGRCh38hg38GRCh38
GRCh372242,296,948 - 42,297,016 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362240,626,893 - 40,626,961 (+)NCBINCBI36Build 36hg18NCBI36
Celera2226,103,182 - 26,103,250 (+)NCBICelera
Cytogenetic Map22q13.2NCBI
HuRef2225,262,647 - 25,262,715 (+)NCBIHuRef
CHM1_12242,257,156 - 42,257,224 (+)NCBICHM1_1
T2T-CHM13v2.02242,379,729 - 42,379,797 (+)NCBIT2T-CHM13v2.0
Mir33
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391582,082,323 - 82,082,391 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1582,082,323 - 82,082,391 (+)EnsemblGRCm39 Ensembl
GRCm381582,198,122 - 82,198,190 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1582,198,122 - 82,198,190 (+)EnsemblGRCm38mm10GRCm38
MGSCv371582,028,552 - 82,028,620 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1584,321,842 - 84,321,910 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1538.54NCBI
MIR33A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11023,456,613 - 23,456,673 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1023,456,613 - 23,456,673 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1023,390,695 - 23,390,755 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01024,201,614 - 24,201,674 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1024,201,614 - 24,201,674 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11023,918,597 - 23,918,657 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01024,239,834 - 24,239,894 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01024,413,986 - 24,414,046 (-)NCBIUU_Cfam_GSD_1.0

miRNA Target Status (No longer updated)

Predicted Targets
Summary Value
Count of predictions:12182
Count of gene targets:6663
Count of transcripts:7193
Interacting mature miRNAs:rno-miR-33-3p, rno-miR-33-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
1 3 3 5 1 6 1 9 7 2 2 4

Sequence


Ensembl Acc Id: ENSRNOT00000053670
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7113,713,855 - 113,713,923 (+)Ensembl
Rnor_6.0 Ensembl7123,431,612 - 123,431,680 (+)Ensembl
RefSeq Acc Id: NR_031847
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87115,593,952 - 115,594,020 (+)NCBI
mRatBN7.27113,713,855 - 113,713,923 (+)NCBI
Rnor_6.07123,431,612 - 123,431,680 (+)NCBI
Rnor_5.07123,415,303 - 123,415,371 (+)NCBI
Celera7110,029,025 - 110,029,093 (+)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2325408 AgrOrtholog
BioCyc Gene G2FUF-32639 BioCyc
Ensembl Genes ENSRNOG00000035547 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000053670 ENTREZGENE
miRBase MI0000874 ENTREZGENE
NCBI Gene 100314214 ENTREZGENE
PhenoGen Mir33 PhenoGen
RatGTEx ENSRNOG00000035547 RatGTEx
RNAcentral URS000015B89D RNACentral
  URS0000483184 RNACentral
  URS000069F62B RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-04-09 Mir33  microRNA 33  Mir33  microRNA mir-33  Name updated 61478 APPROVED
2010-06-02 Mir33  microRNA mir-33      Symbol and Name status set to provisional 70820 PROVISIONAL