Gene: Cyp11b1 (cytochrome P450, family 11, subfamily b, polypeptide 1) Rattus norvegicus
Symbol: Cyp11b1
Name: cytochrome P450, family 11, subfamily b, polypeptide 1
Description: ENCODES a protein that exhibits steroid 11-beta-monooxygenase activity; steroid binding; INVOLVED IN adenosine metabolic process; aldosterone biosynthetic process; cellular response to interferon-gamma; PARTICIPATES IN aldosterone biosynthetic pathway; cortisol biosynthetic pathway; steroid hormone biosynthetic pathway; ASSOCIATED WITH increased systemic arterial systolic blood pressure; ASSOCIATED WITH Fetal Growth Retardation; hypertension; Left Ventricular Hypertrophy; FOUND IN integral component of endoplasmic reticulum membrane; mitochondrion
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: aldosterone synthase; Cp11ba; CYPXIB1; cytochrome P450 11B1, mitochondrial; cytochrome P450(11 beta)-DS; cytochrome P450, subfamily 11B, polypeptide 1; Cytochrome P450, subfamily XIB, polypeptide 1 (steroid 11-beta-hydroxylase); cytochrome P450C11; P450(11 beta)-DS; P450C11; RATCP11BA; steroid 11-beta-hydroxylase
No known orthologs. homologs ...
Is Marker For: Strains:   SD   SS.LEW-(D7Rat73-D7Rat128)/Ayd   LEW.SS-(D7Rat73-D7Rat128)/Ayd  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Genome Annotation Status: not in current annotation release
Rat AssemblyChrPosition (strand)SourceGenome Browsers
RGSC_v3.47112,977,395 - 112,984,080 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17113,077,602 - 113,083,995 (-)NCBI
Cytogenetic Map7q34NCBI

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Position Markers
Related Rat Strains


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cyp11b1
Alliance Gene
Ensembl Gene
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RGD Object Information
RGD ID: 2453
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE