Gene: Cyp11a1 (cytochrome P450, family 11, subfamily a, polypeptide 1) Rattus norvegicus
Symbol: Cyp11a1
Name: cytochrome P450, family 11, subfamily a, polypeptide 1
Description: ENCODES a protein that exhibits cholesterol binding; cholesterol monooxygenase (side-chain-cleaving) activity; heme binding (ortholog); INVOLVED IN biphenyl metabolic process; C21-steroid hormone biosynthetic process; cellular response to antibiotic; PARTICIPATES IN 11-beta-hydroxylase deficiency pathway; 17-alpha-hydroxylase deficiency pathway; 21-alpha-hydroxylase deficiency pathway; ASSOCIATED WITH Brain Injuries; Cardiomegaly; Diabetes Mellitus, Experimental ; FOUND IN mitochondrial crista; mitochondrial inner membrane; mitochondrion; INTERACTS WITH (+)-pilocarpine; (-)-citrinin; (S)-nicotine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cholesterol desmolase; cholesterol side-chain cleavage cytochrome P450; cholesterol side-chain cleavage enzyme; cholesterol side-chain cleavage enzyme, mitochondrial; Cyp11a; Cypxia1; cytochrome P450 11a cholesterol side chain cleavage; cytochrome P450 11A1; cytochrome P450 family 11 subfamily a; cytochrome P450 side-chain cleavage enzyme; cytochrome P450 subfamily 11A; cytochrome P450(scc); cytochrome P450, 11a, cholesterol side; cytochrome P450, subfamily 11A; P450(scc); P450scc
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0862,798,317 - 62,809,848 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0862,525,349 - 62,585,615 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4861,793,976 - 61,805,308 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1861,812,986 - 61,824,536 (+)NCBI
Celera857,887,124 - 57,898,655 (+)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cyp11a1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69325
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE