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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69325
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp11a1
Name: cytochrome P450, family 11, subfamily a, polypeptide 1
Acc ID: CHEBI:88522
Term: Monobutylphthalate
Definition: A phthalic acid monoester that has formula C12H14O4.
Chemical ID: MESH:C028577
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp11a1decreases expressionISOCyp11a1 (Mus musculus)6480464CTDmonobutyl phthalate results in decreased expression of CYP11A1 proteinPMID:36602389
Cyp11a1increases expressionISOCYP11A1 (Homo sapiens)6480464CTDmonobutyl phthalate results in increased expression of CYP11A1 mRNAPMID:29089286
Cyp11a1increases expressionISOCyp11a1 (Mus musculus)6480464CTDmonobutyl phthalate results in increased expression of CYP11A1 mRNAPMID:34280466
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