Cm101 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Cm101 (Cardiac mass QTL 101) Rattus norvegicus

Symbol: Cm101
Name: Cardiac mass QTL 101
RGD ID: 12879881
Previously known as: BpcakmC8QTL1
Trait: heart right ventricle mass   (VT:0007033)    
Measurement Type: heart right ventricle weight to body weight ratio   (CMO:0000914)    
LOD Score: Not Available
P Value: 0.001
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8862,848,139 - 107,848,139RGD_MAPPER_PIPELINE
mRatBN7.2843,296,169 - 98,968,765RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0847,200,750 - 106,394,378RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0860,836,747 - 105,836,747RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4858,548,876 - 103,548,876RGD_MAPPER_PIPELINERGSC3.4
Cross Type: Not Available
Strains Crossed: SS.LEW-(D8Chm14-D8Rat16)/Ayd 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cm101Rathypertension  IAGP 1599557 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cm101Ratabnormal heart right ventricle weight  IAGP 1599557 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cm101Ratheart right ventricle weight to body weight ratio  IDA 1599557 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cm101Ratcontrolled sodium content diet  IDA 1599557 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cm101Ratpost excision weight measurement  IDA 1599557 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cm101RatSS.LEW-(D8Chm14-D8Rat16)/Ayd  IEA 1599557 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cm101Ratheart right ventricle mass  IDA 1599557 RGD 


#
Reference Title
Reference Citation
1. Distinct quantitative trait loci for kidney, cardiac, and aortic mass dissociated from and associated with blood pressure in Dahl congenic rats. Duong C, etal., Mamm Genome. 2006 Dec;17(12):1147-61. Epub 2006 Dec 1.


1 to 20 of 794 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
2734Grik4glutamate ionotropic receptor kainate type subunit 484290304343331990Rat
1305111Arhgef12Rho guanine nucleotide exchange factor 1284335007043475404Rat
1565079Tlcd5TLC domain containing 584348138843486288Rat
621691Pou2f3POU class 2 homeobox 384349540843577795Rat
1305890Oafout at first homolog84359436243612334Rat
1307858Trim29tripartite motif-containing 2984368222143706992Rat
41272318LOC120094130uncharacterized LOC12009413084378126843800378Rat
7617270LOC102555063uncharacterized LOC10255506384382301643830274Rat
11511573LOC108351687uncharacterized LOC10835168784383129143835286Rat
41073558LOC120094131uncharacterized LOC12009413184396438143966974Rat
620791Nectin1nectin cell adhesion molecule 184410177644164863Rat
41291834LOC120094415U6 spliceosomal RNA84425965444259757Rat
11384736LOC108351689uncharacterized LOC10835168984431212444316357Rat
3860Thy1Thy-1 cell surface antigen84438949544394688Rat
621073Usp2ubiquitin specific peptidase 284441145744439668Rat
1307477Mfrpmembrane frizzled-related protein84444563644450859Rat
1308802C1qtnf5C1q and TNF related 584445093444453075Rat
1305953Rnf26ring finger protein 2684445455144456745Rat
41046946LOC120094132uncharacterized LOC12009413284446930544475593Rat
620463Mcammelanoma cell adhesion molecule84447939144487575Rat

1 to 20 of 794 rows
1 to 20 of 1293 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10168D8Wox524785808190958082156Ratregion
10177D8Mit720184653163946531840Ratregion
10178D8Wox411884653172246531840Ratregion
10354D8Bord123085541543055415660Ratregion
33880D8Mit1212485489451654894646Ratregion
33895D8Mit113388864232088642451Ratregion
33957D8Mit1622885848226258482492Ratregion
33973D8Mit219885009524950095447Ratregion
34116D8Mgh1213684600883646008974Ratregion
34152D8Mgh1715086934919469349344Ratregion
34152D8Mgh1715086934919469349344Ratregion
34310D8Mgh414188246075882460899Ratregion
34415D8Mgh614486129029861290444Ratregion
11322D8Hmgc111584622932246229437Ratregion
11444D8Mgh512986764887467649003Ratregion
35987D8Rat3016387038613270386295Ratregion
36161D8Rat3617085423764454237814Ratregion
36257D8Rat3812185161880151618922Ratregion
36309D8Rat4115584762723547627390Ratregion
36390D8Mgh1985859738058597503Ratregion
1 to 20 of 1293 rows

Flank 1: (D8Chm11)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2843,296,169 - 43,296,654 (+)MAPPER
Rnor_6.0847,200,750 - 47,201,232RGD
Flank 2: (D8Rat15)
Rat AssemblyChrPosition (strand)Source
GRCr88107,847,991 - 107,848,139 (+)Marker Load Pipeline
mRatBN7.2898,968,617 - 98,968,765 (+)MAPPER
Rnor_6.08106,394,231 - 106,394,378NCBI
Rnor_5.08105,836,600 - 105,836,747UniSTS
RGSC_v3.48103,548,728 - 103,548,876RGD
RGSC_v3.48103,548,729 - 103,548,876UniSTS
RGSC_v3.18103,568,183 - 103,568,331RGD
Celera898,380,264 - 98,380,411UniSTS
RH 2.0 Map8844.1RGD
SHRSP x BN Map860.66RGD
Cytogenetic Map8q31UniSTS


1 to 10 of 101 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83084815461290444Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
8693654Alc32Alcohol consumption QTL 3220.755drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)888612425107550209Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85009524982460899Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat

1 to 10 of 101 rows


Note Type Note Reference
qtl_general number of animals used: 7 gender: male 1599557
qtl_general also affects cardiac mass, heart left ventricle mass, aortic mass, kidney mass, blood pressure and body mass 1599557
qtl_statistics_details software package used: ANOVA followed by Dunnett test in the SYSTAT 9 program 1599557
qtl_trait_method measurement method: selected males were weaned at 21 days of age then fed 2% NaCl diet starting from 35 days of age, at 14 weeks animals were decapitated, organs removed, blotted and weighed 1599557
qtl_trait_method heart was dissected into left ventricle plus septum and right ventricle 1599557