Gene: Scn4b (sodium voltage-gated channel beta subunit 4) Rattus norvegicus
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Symbol: Scn4b
Name: sodium voltage-gated channel beta subunit 4
Description: Predicted to have ion channel binding activity; sodium channel regulator activity; and voltage-gated sodium channel activity involved in cardiac muscle cell action potential. Predicted to be involved in several processes, including cardiac muscle cell action potential; regulation of heart rate by cardiac conduction; and regulation of sodium ion transport. Localizes to the plasma membrane. Human ortholog(s) of this gene implicated in long QT syndrome 10. Orthologous to human SCN4B (sodium voltage-gated channel beta subunit 4); INTERACTS WITH 2,3,4,7,8-Pentachlorodibenzofuran; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: sodium channel accessory subunit; sodium channel beta 4 subunit; sodium channel subunit beta-4; sodium channel, type 4, beta subunit; sodium channel, type IV, beta; sodium channel, voltage-gated, type IV, beta; sodium channel, voltage-gated, type IV, beta subunit
Orthologs:
Homo sapiens (human) : SCN4B (sodium voltage-gated channel beta subunit 4)  HGNC  Alliance
Mus musculus (house mouse) : Scn4b (sodium channel, type IV, beta)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Scn4b (sodium voltage-gated channel beta subunit 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SCN4B (sodium voltage-gated channel beta subunit 4)
Canis lupus familiaris (dog) : SCN4B (sodium voltage-gated channel beta subunit 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scn4b (sodium voltage-gated channel beta subunit 4)
Sus scrofa (pig) : SCN4B (sodium voltage-gated channel beta subunit 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0849,441,106 - 49,456,279 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0848,067,555 - 48,082,728 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4848,091,561 - 48,106,735 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1848,109,134 - 48,115,501 (+)NCBI
Celera845,031,630 - 45,046,803 (+)NCBICelera
Cytogenetic Map8q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Scn4b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 631404
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.