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Gene: Ncam1 (neural cell adhesion molecule 1) Rattus norvegicus
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Symbol: Ncam1
Name: neural cell adhesion molecule 1
Description: Exhibits LRR domain binding activity and phosphatase binding activity. Involved in several processes, including aging; axon development; and positive regulation of cardiac muscle cell proliferation. Localizes to several cellular components, including the Schaffer collateral - CA1 synapse; glutamatergic synapse; and integral component of synaptic membrane. Biomarker of congestive heart failure and hypothyroidism. Human ortholog(s) of this gene implicated in bipolar disorder and pancreatic cancer. Orthologous to human NCAM1 (neural cell adhesion molecule 1); PARTICIPATES IN fibroblast growth factor signaling pathway; prion disease pathway; INTERACTS WITH 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Cd56; Cell adhesion molecule neural (CD56); cell adhesion molecule, neural (CD56); MGC124601; N-CAM; N-CAM-1; Ncam; NCAM-1; NCAM-C; NCAMC; neural cell adhesion molecule
Orthologs:
Homo sapiens (human) : NCAM1 (neural cell adhesion molecule 1)  HGNC  Alliance
Mus musculus (house mouse) : Ncam1 (neural cell adhesion molecule 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ncam1 (neural cell adhesion molecule 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NCAM1 (neural cell adhesion molecule 1)
Canis lupus familiaris (dog) : NCAM1 (neural cell adhesion molecule 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ncam1 (neural cell adhesion molecule 1)
Sus scrofa (pig) : NCAM1 (neural cell adhesion molecule 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0853,836,797 - 54,134,881 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0852,456,154 - 52,755,707 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4852,822,350 - 53,120,572 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1852,841,403 - 53,139,626 (-)NCBI
Celera849,420,106 - 49,716,981 (-)NCBICelera
Cytogenetic Map8q23NCBI
RH 3.4 Map8537.1RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ncam1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 67378
Created: 2001-06-01
Species: Rattus norvegicus
Last Modified: 2019-06-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.