Nlrx1 (NLR family member X1) - Rat Genome Database

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Gene: Nlrx1 (NLR family member X1) Rattus norvegicus
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Symbol: Nlrx1
Name: NLR family member X1
RGD ID: 1311293
Description: Predicted to enable ATP binding activity. Predicted to be involved in negative regulation of I-kappaB kinase/NF-kappaB signaling. Predicted to act upstream of or within negative regulation of cytokine production and negative regulation of defense response. Predicted to be located in cell junction and plasma membrane. Predicted to be active in mitochondrion. Orthologous to human NLRX1 (NLR family member X1); PARTICIPATES IN influenza A pathway; Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; INTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC315599; RGD1311293; similar to CDNA sequence BC034204
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2844,588,476 - 44,606,678 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl844,590,048 - 44,606,484 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx850,085,296 - 50,102,169 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0848,364,014 - 48,380,887 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0846,234,836 - 46,251,261 (-)NCBIRnor_WKY
Rnor_6.0848,583,559 - 48,600,203 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl848,584,071 - 48,597,867 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0847,202,115 - 47,218,306 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4847,230,800 - 47,246,976 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1847,239,565 - 47,255,742 (-)NCBI
Celera844,176,760 - 44,192,570 (-)NCBICelera
Cytogenetic Map8q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:18614015   PMID:21703540   PMID:32099552   PMID:35259612  


Genomics

Comparative Map Data
Nlrx1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2844,588,476 - 44,606,678 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl844,590,048 - 44,606,484 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx850,085,296 - 50,102,169 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0848,364,014 - 48,380,887 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0846,234,836 - 46,251,261 (-)NCBIRnor_WKY
Rnor_6.0848,583,559 - 48,600,203 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl848,584,071 - 48,597,867 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0847,202,115 - 47,218,306 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4847,230,800 - 47,246,976 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1847,239,565 - 47,255,742 (-)NCBI
Celera844,176,760 - 44,192,570 (-)NCBICelera
Cytogenetic Map8q22NCBI
NLRX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811119,168,334 - 119,184,016 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl11119,166,568 - 119,184,016 (+)EnsemblGRCh38hg38GRCh38
GRCh3711119,039,043 - 119,054,725 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611118,544,650 - 118,559,935 (+)NCBINCBI36Build 36hg18NCBI36
Celera11116,199,239 - 116,214,520 (+)NCBICelera
Cytogenetic Map11q23.3NCBI
HuRef11114,978,864 - 114,994,189 (+)NCBIHuRef
CHM1_111118,925,713 - 118,940,992 (+)NCBICHM1_1
T2T-CHM13v2.011119,188,702 - 119,204,385 (+)NCBIT2T-CHM13v2.0
Nlrx1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39944,164,010 - 44,179,896 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl944,164,014 - 44,179,896 (-)EnsemblGRCm39 Ensembl
GRCm38944,252,713 - 44,268,599 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl944,252,717 - 44,268,599 (-)EnsemblGRCm38mm10GRCm38
MGSCv37944,060,796 - 44,076,682 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36944,003,712 - 44,019,393 (-)NCBIMGSCv36mm8
MGSCv36944,510,207 - 44,524,609 (-)NCBIMGSCv36mm8
Celera941,516,710 - 41,519,423 (-)NCBICelera
Cytogenetic Map9A5.2NCBI
Nlrx1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541220,275,917 - 20,287,414 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541220,275,767 - 20,287,414 (+)NCBIChiLan1.0ChiLan1.0
NLRX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.111117,935,341 - 117,950,728 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11117,935,444 - 117,950,728 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v011114,007,415 - 114,022,712 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
NLRX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1514,692,621 - 14,705,214 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl514,564,935 - 14,705,257 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha514,745,724 - 14,758,327 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0514,635,986 - 14,648,591 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl514,509,217 - 14,648,560 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1514,774,069 - 14,786,677 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0514,678,275 - 14,690,875 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0514,718,488 - 14,731,104 (-)NCBIUU_Cfam_GSD_1.0
Nlrx1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947101,187,565 - 101,199,769 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365424,109,136 - 4,122,978 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049365424,105,980 - 4,121,176 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NLRX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl946,384,948 - 46,400,983 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1946,384,373 - 46,400,752 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2951,420,072 - 51,435,898 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NLRX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11110,541,777 - 110,559,846 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1110,545,190 - 110,560,149 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604315,474,057 - 15,492,227 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nlrx1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478414,549,834 - 14,563,398 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478414,549,926 - 14,564,028 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nlrx1
101 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:71
Count of miRNA genes:67
Interacting mature miRNAs:68
Transcripts:ENSRNOT00000011620
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)8209764047097640Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)8209764047097640Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)8209764047097640Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)8209764047097640Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)8470581049705810Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)8470581049705810Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)8470581049705810Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8767057852670578Rat
1354595Despr4Despair related QTL 42.160.0036locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)8768895552688955Rat
1354627Despr14Despair related QTL 140.0056locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)8768895552688955Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)8873663553736635Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)8873663553736635Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)8971222053356647Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1558646Swd5Spike wave discharge measurement QTL 53.450.00036brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)81490675159906751Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)81629044461290444Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)82266233067662330Rat
2303564Gluco43Glucose level QTL 433blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)82613018771130187Rat
2303572Insul13Insulin level QTL 132blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)82613018771130187Rat
1359021Bp271Blood pressure QTL 2711.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82664491246711092Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)82720571554998217Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)82720571599103503Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)82720571599103503Rat
1331804Cm30Cardiac mass QTL 303.77443heart mass (VT:0007028)heart wet weight (CMO:0000069)82824291253961020Rat
1300146Rf17Renal function QTL 172.9renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)82824291273242912Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
2302278Gluco36Glucose level QTL 364.2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)82950266550095447Rat
724514Uae15Urinary albumin excretion QTL 152.9urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)82950266570386295Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)83018886794457446Rat
1331744Bp217Blood pressure QTL 2173.398arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815458482492Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83084815461290444Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83084815461290444Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83084815482460899Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83084815482460899Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83084815482460899Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83084815482460899Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83085640475856404Rat
1582222Epfw2Epididymal fat weight QTL 23.20.0005epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)83173772976737729Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83555193880551938Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83646953599083736Rat
737824Hcar10Hepatocarcinoma resistance QTL 102.9liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)84071306682925667Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84071306693965294Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)84186687675097878Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
631216Stl9Serum triglyceride level QTL 94.710.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)84186701070386132Rat
5684993Bmd84Bone mineral density QTL 844.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)84269268450095447Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)84329616998968765Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)84329616998968765Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)84329616998968765Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)84329616998968765Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)84329616998968765Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)84329616998968765Rat

Markers in Region
RH129818  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2844,590,078 - 44,590,261 (+)MAPPERmRatBN7.2
Rnor_6.0848,583,594 - 48,583,776NCBIRnor6.0
Rnor_5.0847,202,164 - 47,202,346UniSTSRnor5.0
RGSC_v3.4847,230,835 - 47,231,017UniSTSRGSC3.4
Celera844,176,795 - 44,176,977UniSTS
RH 3.4 Map8428.0UniSTS
Cytogenetic Map8q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 2 2 2 2 5 3 3 10 3 2
Low 3 42 55 39 19 39 6 6 71 32 30 8 6
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000077958   ⟹   ENSRNOP00000071934
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl844,590,048 - 44,606,484 (-)Ensembl
Rnor_6.0 Ensembl848,584,071 - 48,597,867 (-)Ensembl
RefSeq Acc Id: NM_001025010   ⟹   NP_001020181
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2844,590,044 - 44,606,474 (-)NCBI
Rnor_6.0848,583,559 - 48,600,203 (-)NCBI
Rnor_5.0847,202,115 - 47,218,306 (-)NCBI
RGSC_v3.4847,230,800 - 47,246,976 (-)RGD
Celera844,176,760 - 44,192,570 (-)RGD
Sequence:
RefSeq Acc Id: XM_039081422   ⟹   XP_038937350
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2844,590,043 - 44,606,678 (-)NCBI
RefSeq Acc Id: XM_039081423   ⟹   XP_038937351
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2844,590,043 - 44,606,678 (-)NCBI
RefSeq Acc Id: XM_039081424   ⟹   XP_038937352
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2844,590,043 - 44,605,749 (-)NCBI
RefSeq Acc Id: XR_005487814
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2844,588,476 - 44,606,678 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001020181   ⟸   NM_001025010
- Peptide Label: precursor
- UniProtKB: Q5FVQ8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000071934   ⟸   ENSRNOT00000077958
RefSeq Acc Id: XP_038937350   ⟸   XM_039081422
- Peptide Label: isoform X1
- UniProtKB: Q5FVQ8 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038937351   ⟸   XM_039081423
- Peptide Label: isoform X1
- UniProtKB: Q5FVQ8 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038937352   ⟸   XM_039081424
- Peptide Label: isoform X1
- UniProtKB: Q5FVQ8 (UniProtKB/Swiss-Prot)
Protein Domains
LRRCT   LRRNT   NACHT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5FVQ8-F1-model_v2 AlphaFold Q5FVQ8 1-973 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311293 AgrOrtholog
BioCyc Gene G2FUF-30730 BioCyc
Ensembl Genes ENSRNOG00000052386 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000071934 ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000077958 ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7325650 IMAGE-MGC_LOAD
InterPro Leu-rich_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NACHT_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:315599 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108817 IMAGE-MGC_LOAD
NCBI Gene 315599 ENTREZGENE
Pfam LRR_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NACHT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nlrx1 PhenoGen
PROSITE NACHT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K1Q1_RAT UniProtKB/TrEMBL
  NLRX1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-27 Nlrx1  NLR family member X1  RGD1311293  similar to CDNA sequence BC034204  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1311293  similar to CDNA sequence BC034204  RGD1311293_predicted  similar to CDNA sequence BC034204 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1311293_predicted  similar to CDNA sequence BC034204 (predicted)  LOC315599_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC315599_predicted  similar to CDNA sequence BC034204 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL