Symbol:
Tnfaip8l3
Name:
TNF alpha induced protein 8 like 3
RGD ID:
1311533
Description:
Predicted to enable phosphatidylinositol binding activity and phosphatidylinositol transfer activity. Predicted to be involved in 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process; phospholipid transport; and positive regulation of ERK1 and ERK2 cascade. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be active in cytoplasm. Orthologous to human TNFAIP8L3 (TNF alpha induced protein 8 like 3); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
LOC315673; RGD1311533; similar to TNF-induced protein; tumor necrosis factor alpha-induced protein 8-like protein 3; tumor necrosis factor, alpha-induced protein 8-like 3
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
TNFAIP8L3 (TNF alpha induced protein 8 like 3)
HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
Tnfaip8l3 (tumor necrosis factor, alpha-induced protein 8-like 3)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Tnfaip8l3 (TNF alpha induced protein 8 like 3)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
TNFAIP8L3 (TNF alpha induced protein 8 like 3)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
TNFAIP8L3 (TNF alpha induced protein 8 like 3)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Tnfaip8l3 (TNF alpha induced protein 8 like 3)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
TNFAIP8L3 (TNF alpha induced protein 8 like 3)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
TNFAIP8L3 (TNF alpha induced protein 8 like 3)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Tnfaip8l3 (TNF alpha induced protein 8 like 3)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
TRMT11 (tRNA methyltransferase 11 homolog)
HGNC
OMA
Alliance orthologs 3
Homo sapiens (human):
TNFAIP8L3 (TNF alpha induced protein 8 like 3)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Tnfaip8l3 (tumor necrosis factor, alpha-induced protein 8-like 3)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
tnfaip8l3 (tumor necrosis factor, alpha-induced protein 8-like 3)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
sigmar
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
tnfaip8l3
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 8 63,309,683 - 63,351,687 (-) NCBI GRCr8 mRatBN7.2 8 54,413,503 - 54,455,512 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 8 54,414,457 - 54,500,079 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 8 59,947,931 - 59,989,780 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 8 58,226,957 - 58,268,800 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 8 56,091,204 - 56,133,049 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 8 58,599,382 - 58,648,045 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 8 58,602,127 - 58,647,933 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 8 57,179,020 - 57,227,112 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 8 57,510,316 - 57,643,331 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 8 57,529,328 - 57,570,396 (-) NCBI Celera 8 53,903,174 - 53,947,810 (-) NCBI Celera Cytogenetic Map 8 q24 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Tnfaip8l3 Rat 17beta-estradiol multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of TNFAIP8L3 mRNA CTD PMID:32741896 Tnfaip8l3 Rat 17beta-estradiol decreases expression ISO Tnfaip8l3 (Mus musculus) 6480464 Estradiol results in decreased expression of TNFAIP8L3 mRNA CTD PMID:39298647 Tnfaip8l3 Rat 17beta-estradiol 3-benzoate multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of TNFAIP8L3 mRNA CTD PMID:32741896 Tnfaip8l3 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Tnfaip8l3 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of TNFAIP8L3 mRNA CTD PMID:26377647 Tnfaip8l3 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of TNFAIP8L3 mRNA CTD PMID:32109520 Tnfaip8l3 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Tnfaip8l3 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of TNFAIP8L3 mRNA CTD PMID:21889950 more ... Tnfaip8l3 Rat 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:32119087 Tnfaip8l3 Rat 4,4'-sulfonyldiphenol decreases expression ISO Tnfaip8l3 (Mus musculus) 6480464 bisphenol S results in decreased expression of TNFAIP8L3 mRNA CTD PMID:39298647 Tnfaip8l3 Rat aflatoxin B1 increases expression ISO TNFAIP8L3 (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of TNFAIP8L3 mRNA CTD PMID:22100608 Tnfaip8l3 Rat aflatoxin B1 decreases methylation ISO TNFAIP8L3 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of TNFAIP8L3 gene CTD PMID:27153756 Tnfaip8l3 Rat aldehydo-D-glucose multiple interactions ISO Tnfaip8l3 (Mus musculus) 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of TNFAIP8L3 mRNA CTD PMID:37567420 Tnfaip8l3 Rat alpha-Zearalanol multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of TNFAIP8L3 mRNA CTD PMID:35163327 Tnfaip8l3 Rat arsane multiple interactions ISO TNFAIP8L3 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of TNFAIP8L3 mRNA CTD PMID:32525701 Tnfaip8l3 Rat arsenic atom multiple interactions ISO TNFAIP8L3 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of TNFAIP8L3 mRNA CTD PMID:32525701 Tnfaip8l3 Rat atrazine affects methylation EXP 6480464 Atrazine affects the methylation of TNFAIP8L3 gene CTD PMID:28931070 and PMID:35440735 Tnfaip8l3 Rat benzo[a]pyrene increases expression ISO TNFAIP8L3 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of TNFAIP8L3 mRNA CTD PMID:20064835 and PMID:32234424 Tnfaip8l3 Rat benzo[a]pyrene increases expression ISO Tnfaip8l3 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of TNFAIP8L3 mRNA CTD PMID:32417428 Tnfaip8l3 Rat benzo[a]pyrene decreases methylation ISO TNFAIP8L3 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of TNFAIP8L3 promoter CTD PMID:27901495 Tnfaip8l3 Rat benzo[e]pyrene decreases methylation ISO TNFAIP8L3 (Homo sapiens) 6480464 benzo(e)pyrene results in decreased methylation of TNFAIP8L3 exon CTD PMID:30157460 Tnfaip8l3 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of TNFAIP8L3 mRNA CTD PMID:25181051 Tnfaip8l3 Rat bisphenol A increases expression ISO Tnfaip8l3 (Mus musculus) 6480464 bisphenol A results in increased expression of TNFAIP8L3 mRNA CTD PMID:32156529 Tnfaip8l3 Rat bisphenol A increases expression ISO TNFAIP8L3 (Homo sapiens) 6480464 bisphenol A results in increased expression of TNFAIP8L3 mRNA CTD PMID:27685785 Tnfaip8l3 Rat bromobenzene decreases expression EXP 6480464 bromobenzene results in decreased expression of TNFAIP8L3 mRNA CTD PMID:32479839 Tnfaip8l3 Rat butan-1-ol multiple interactions ISO TNFAIP8L3 (Homo sapiens) 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of TNFAIP8L3 mRNA CTD PMID:29432896 Tnfaip8l3 Rat cadmium dichloride increases expression ISO TNFAIP8L3 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of TNFAIP8L3 mRNA CTD PMID:21457566 Tnfaip8l3 Rat calcitriol increases expression ISO TNFAIP8L3 (Homo sapiens) 6480464 Calcitriol results in increased expression of TNFAIP8L3 mRNA CTD PMID:16002434 Tnfaip8l3 Rat CGP 52608 multiple interactions ISO TNFAIP8L3 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to TNFAIP8L3 gene] CTD PMID:28238834 Tnfaip8l3 Rat cobalt dichloride decreases expression ISO TNFAIP8L3 (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of TNFAIP8L3 mRNA CTD PMID:19320972 Tnfaip8l3 Rat D-glucose multiple interactions ISO Tnfaip8l3 (Mus musculus) 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of TNFAIP8L3 mRNA CTD PMID:37567420 Tnfaip8l3 Rat dibenzofurans increases expression ISO Tnfaip8l3 (Mus musculus) 6480464 Dibenzofurans results in increased expression of TNFAIP8L3 mRNA CTD PMID:34254344 Tnfaip8l3 Rat doxorubicin decreases expression ISO TNFAIP8L3 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of TNFAIP8L3 mRNA CTD PMID:29803840 Tnfaip8l3 Rat ethanol multiple interactions ISO TNFAIP8L3 (Homo sapiens) 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of TNFAIP8L3 mRNA CTD PMID:29432896 Tnfaip8l3 Rat fructose multiple interactions ISO Tnfaip8l3 (Mus musculus) 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of TNFAIP8L3 mRNA CTD PMID:37567420 Tnfaip8l3 Rat glucose multiple interactions ISO Tnfaip8l3 (Mus musculus) 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of TNFAIP8L3 mRNA CTD PMID:37567420 Tnfaip8l3 Rat herbicide multiple interactions ISO Tnfaip8l3 (Mus musculus) 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of TNFAIP8L3 mRNA CTD PMID:37567420 Tnfaip8l3 Rat isobutanol multiple interactions ISO TNFAIP8L3 (Homo sapiens) 6480464 [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of TNFAIP8L3 mRNA CTD PMID:29432896 Tnfaip8l3 Rat lipopolysaccharide multiple interactions ISO TNFAIP8L3 (Homo sapiens) 6480464 [S-(1 more ... CTD PMID:35811015 Tnfaip8l3 Rat lipopolysaccharide decreases expression ISO TNFAIP8L3 (Homo sapiens) 6480464 Lipopolysaccharides results in decreased expression of TNFAIP8L3 mRNA CTD PMID:35811015 Tnfaip8l3 Rat malathion decreases expression ISO TNFAIP8L3 (Homo sapiens) 6480464 Malathion results in decreased expression of TNFAIP8L3 mRNA CTD PMID:37047231 Tnfaip8l3 Rat methapyrilene decreases methylation ISO TNFAIP8L3 (Homo sapiens) 6480464 Methapyrilene results in decreased methylation of TNFAIP8L3 exon CTD PMID:30157460 Tnfaip8l3 Rat ozone multiple interactions ISO Tnfaip8l3 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of TNFAIP8L3 mRNA CTD PMID:34911549 Tnfaip8l3 Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of TNFAIP8L3 mRNA CTD PMID:33387578 Tnfaip8l3 Rat pentachlorophenol increases expression ISO TNFAIP8L3 (Homo sapiens) 6480464 Pentachlorophenol results in increased expression of TNFAIP8L3 mRNA CTD PMID:35550411 Tnfaip8l3 Rat perfluorooctanoic acid multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of TNFAIP8L3 mRNA CTD PMID:35163327 Tnfaip8l3 Rat potassium chromate decreases expression ISO TNFAIP8L3 (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of TNFAIP8L3 mRNA CTD PMID:22714537 Tnfaip8l3 Rat rotenone increases expression ISO Tnfaip8l3 (Mus musculus) 6480464 Rotenone results in increased expression of TNFAIP8L3 mRNA CTD PMID:32937126 Tnfaip8l3 Rat S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO TNFAIP8L3 (Homo sapiens) 6480464 [S-(1 more ... CTD PMID:35811015 Tnfaip8l3 Rat S-(1,2-dichlorovinyl)-L-cysteine decreases expression ISO TNFAIP8L3 (Homo sapiens) 6480464 S-(1 and 2-dichlorovinyl)cysteine results in decreased expression of TNFAIP8L3 mRNA CTD PMID:35811015 Tnfaip8l3 Rat silicon dioxide increases expression ISO TNFAIP8L3 (Homo sapiens) 6480464 Silicon Dioxide analog results in increased expression of TNFAIP8L3 mRNA CTD PMID:25895662 Tnfaip8l3 Rat sodium arsenate multiple interactions ISO TNFAIP8L3 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of TNFAIP8L3 mRNA CTD PMID:32525701 Tnfaip8l3 Rat temozolomide decreases expression ISO TNFAIP8L3 (Homo sapiens) 6480464 Temozolomide results in decreased expression of TNFAIP8L3 mRNA CTD PMID:31758290 Tnfaip8l3 Rat testosterone multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of TNFAIP8L3 mRNA CTD PMID:32741896 Tnfaip8l3 Rat thiram decreases expression ISO TNFAIP8L3 (Homo sapiens) 6480464 Thiram results in decreased expression of TNFAIP8L3 mRNA CTD PMID:38568856 Tnfaip8l3 Rat titanium dioxide decreases methylation ISO Tnfaip8l3 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of TNFAIP8L3 gene CTD PMID:35295148 Tnfaip8l3 Rat Triptolide decreases expression ISO Tnfaip8l3 (Mus musculus) 6480464 triptolide results in decreased expression of TNFAIP8L3 mRNA CTD PMID:32835833 Tnfaip8l3 Rat urethane decreases expression ISO TNFAIP8L3 (Homo sapiens) 6480464 Urethane results in decreased expression of TNFAIP8L3 mRNA CTD PMID:28818685
17beta-estradiol (EXP,ISO) 17beta-estradiol 3-benzoate (EXP) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 3,3',4,4',5-pentachlorobiphenyl (EXP) 4,4'-sulfonyldiphenol (ISO) aflatoxin B1 (ISO) aldehydo-D-glucose (ISO) alpha-Zearalanol (EXP) arsane (ISO) arsenic atom (ISO) atrazine (EXP) benzo[a]pyrene (ISO) benzo[e]pyrene (ISO) bisphenol A (EXP,ISO) bromobenzene (EXP) butan-1-ol (ISO) cadmium dichloride (ISO) calcitriol (ISO) CGP 52608 (ISO) cobalt dichloride (ISO) D-glucose (ISO) dibenzofurans (ISO) doxorubicin (ISO) ethanol (ISO) fructose (ISO) glucose (ISO) herbicide (ISO) isobutanol (ISO) lipopolysaccharide (ISO) malathion (ISO) methapyrilene (ISO) ozone (ISO) paracetamol (EXP) pentachlorophenol (ISO) perfluorooctanoic acid (EXP) potassium chromate (ISO) rotenone (ISO) S-(1,2-dichlorovinyl)-L-cysteine (ISO) silicon dioxide (ISO) sodium arsenate (ISO) temozolomide (ISO) testosterone (EXP) thiram (ISO) titanium dioxide (ISO) Triptolide (ISO) urethane (ISO)
Tnfaip8l3 (Rattus norvegicus - Norway rat)
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 8 63,309,683 - 63,351,687 (-) NCBI GRCr8 mRatBN7.2 8 54,413,503 - 54,455,512 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 8 54,414,457 - 54,500,079 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 8 59,947,931 - 59,989,780 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 8 58,226,957 - 58,268,800 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 8 56,091,204 - 56,133,049 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 8 58,599,382 - 58,648,045 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 8 58,602,127 - 58,647,933 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 8 57,179,020 - 57,227,112 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 8 57,510,316 - 57,643,331 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 8 57,529,328 - 57,570,396 (-) NCBI Celera 8 53,903,174 - 53,947,810 (-) NCBI Celera Cytogenetic Map 8 q24 NCBI
TNFAIP8L3 (Homo sapiens - human)
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 15 51,056,601 - 51,105,276 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 15 51,056,598 - 51,105,276 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 15 51,348,798 - 51,397,473 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 15 49,136,090 - 49,184,765 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Celera 15 28,242,207 - 28,290,874 (-) NCBI Celera Cytogenetic Map 15 q21.2 NCBI HuRef 15 28,178,765 - 28,227,494 (-) NCBI HuRef CHM1_1 15 51,466,882 - 51,515,573 (-) NCBI CHM1_1 T2T-CHM13v2.0 15 48,864,239 - 48,912,949 (-) NCBI T2T-CHM13v2.0
Tnfaip8l3 (Mus musculus - house mouse)
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 9 53,932,890 - 53,975,695 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 9 53,930,689 - 53,975,672 (-) Ensembl GRCm39 Ensembl GRCm38 9 54,025,606 - 54,068,411 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 9 54,023,405 - 54,068,388 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 9 53,873,413 - 53,916,218 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 9 53,823,745 - 53,866,544 (-) NCBI MGSCv36 mm8 Celera 9 51,274,501 - 51,317,446 (-) NCBI Celera Cytogenetic Map 9 A5.3 NCBI cM Map 9 29.46 NCBI
Tnfaip8l3 (Chinchilla lanigera - long-tailed chinchilla)
Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 NW_004955409 3,427,332 - 3,451,809 (+) NCBI ChiLan1.0 ChiLan1.0
TNFAIP8L3 (Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 16 40,303,340 - 40,341,185 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 15 44,484,800 - 44,521,730 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 15 30,008,024 - 30,046,021 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 15 48,342,433 - 48,380,146 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 15 48,343,714 - 48,390,020 (-) Ensembl panpan1.1 panPan2
TNFAIP8L3 (Canis lupus familiaris - dog)
Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 30 16,822,069 - 16,840,284 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 30 16,822,969 - 16,823,529 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 30 16,748,130 - 16,785,718 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 30 16,966,607 - 17,004,190 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 30 16,966,614 - 17,004,149 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 30 16,888,885 - 16,926,459 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 30 17,006,362 - 17,043,937 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 30 17,113,049 - 17,150,645 (-) NCBI UU_Cfam_GSD_1.0
Tnfaip8l3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024408640 95,103,966 - 95,139,125 (-) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936471 12,951,701 - 12,987,232 (-) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936471 12,952,064 - 12,987,178 (-) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
TNFAIP8L3 (Sus scrofa - pig)
Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 1 120,807,392 - 120,849,826 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 1 120,807,533 - 120,849,830 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 1 134,118,751 - 134,160,913 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
TNFAIP8L3 (Chlorocebus sabaeus - green monkey)
Tnfaip8l3 (Heterocephalus glaber - naked mole-rat)
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Predicted Target Of
Count of predictions: 110 Count of miRNA genes: 91 Interacting mature miRNAs: 96 Transcripts: ENSRNOT00000038830 Prediction methods: Microtar, Miranda, Rnahybrid Result types: miRGate_prediction
1298065 Scl16 Serum cholesterol level QTL 16 3.8 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 8 30856404 75856404 Rat 1554321 Bmd3 Bone mineral density QTL 3 7.9 0.0001 femur mineral mass (VT:0010011) volumetric bone mineral density (CMO:0001553) 8 40952565 123900184 Rat 1578769 Uae31 Urinary albumin excretion QTL 31 3.3 0.001 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 8 30848154 101699754 Rat 1298079 Activ2 Activity QTL 2 9.5 0.000001 voluntary movement trait (VT:0003491) rearing measurement (CMO:0001515) 8 41866876 86866876 Rat 11556286 Cm81 Cardiac mass QTL 81 0.01 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 8 30848154 61290444 Rat 70161 Bp62 Blood pressure QTL 62 2.9 0.001 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 8 42692684 90165460 Rat 1578765 Klgr1 Kidney lesion grade QTL 1 3.3 0.0001 kidney morphology trait (VT:0002135) organ lesion measurement (CMO:0000677) 8 30848154 101699754 Rat 1582222 Epfw2 Epididymal fat weight QTL 2 3.2 0.0005 epididymal fat pad mass (VT:0010421) epididymal fat pad weight to body weight ratio (CMO:0000658) 8 31737729 76737729 Rat 61464 Niddm11 Non-insulin dependent diabetes mellitus QTL 11 3.1 0.001 blood insulin amount (VT:0001560) plasma insulin level (CMO:0000342) 8 35582032 80582032 Rat 4889938 Bss89 Bone structure and strength QTL 89 3.8 tibia size trait (VT:0100001) tibia cortical bone volume (CMO:0001725) 8 50095249 82460899 Rat 1578755 Pur5 Proteinuria QTL 5 3.3 0.0001 urine total protein amount (VT:0000032) urine total protein excretion rate (CMO:0000756) 8 30848154 101699754 Rat 1300146 Rf17 Renal function QTL 17 2.9 renal blood flow trait (VT:2000006) absolute change in renal blood flow rate (CMO:0001168) 8 28242912 73242912 Rat 8662823 Vetf5 Vascular elastic tissue fragility QTL 5 1.9 artery integrity trait (VT:0010639) patent ductus arteriosus score (CMO:0002566) 8 28242912 99525068 Rat 2313088 Bss75 Bone structure and strength QTL 75 3.1 0.0001 body length (VT:0001256) body length, nose to rump (CMO:0000079) 8 30848154 82460899 Rat 1358896 Bp262 Blood pressure QTL 262 2.89 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 8 27205715 99103503 Rat 731182 Uae24 Urinary albumin excretion QTL 24 6.4 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 8 19331152 93965294 Rat 1300150 Cm3 Cardiac mass QTL 3 3.97 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 8 54237814 55523877 Rat 724514 Uae15 Urinary albumin excretion QTL 15 2.9 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 8 29502665 70386295 Rat 61353 Bp35 Blood pressure QTL 35 0.001 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 8 30848154 61290444 Rat 631842 Inf1 Infertility severity QTL 1 4.1 0.001 seminal gland mass (VT:0010524) seminal vesicle wet weight (CMO:0001603) 8 22662330 67662330 Rat 737824 Hcar10 Hepatocarcinoma resistance QTL 10 2.9 liver integrity trait (VT:0010547) liver tumorous lesion number (CMO:0001068) 8 40713066 82925667 Rat 1359033 Bp273 Blood pressure QTL 273 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 8 30848154 61290444 Rat 1331769 Rf39 Renal function QTL 39 3.871 urine output (VT:0003620) timed urine volume (CMO:0000260) 8 41866876 75097878 Rat 61358 Bp39 Blood pressure QTL 39 2 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 8 35551938 80551938 Rat 1358906 Bp253 Blood pressure QTL 253 4 0.0004 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 8 40713066 93965294 Rat 1358907 Cm40 Cardiac mass QTL 40 1.89 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 8 27205715 99103503 Rat 1331744 Bp217 Blood pressure QTL 217 3.398 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 8 30848154 58482492 Rat 70197 BpQTLcluster8 Blood pressure QTL cluster 8 3.482 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 8 46531639 119088626 Rat 2316950 Scl66 Serum cholesterol level QTL 66 4.1 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 8 30848259 105647037 Rat 1582254 Kidm31 Kidney mass QTL 31 3 kidney mass (VT:0002707) both kidneys wet weight (CMO:0000085) 8 54237644 85365202 Rat 10402857 Bp380 Blood pressure QTL 380 0.95 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 8 53968765 98968765 Rat 1358892 Kidm26 Kidney mass QTL 26 3.69 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 8 27205715 99103503 Rat 631216 Stl9 Serum triglyceride level QTL 9 4.71 0.0001 blood triglyceride amount (VT:0002644) serum triglyceride level (CMO:0000360) 8 41867010 70386132 Rat 5684973 Bss100 Bone structure and strength QTL 100 4.7 tibia area (VT:1000281) tibia area measurement (CMO:0001382) 8 50095249 82460899 Rat 1582243 Bw66 Body weight QTL 66 3.4 0.0048 body mass (VT:0001259) body weight (CMO:0000012) 8 54237644 85365202 Rat 61373 Mcs4 Mammary carcinoma susceptibility QTL 4 1.1 mammary gland integrity trait (VT:0010552) mammary tumor number (CMO:0000343) 8 16290444 61290444 Rat 2313057 Bss76 Bone structure and strength QTL 76 3 0.0001 tibia size trait (VT:0100001) tibia midshaft cross-sectional area (CMO:0001717) 8 30848154 82460899 Rat 12879878 Bw183 Body weight QTL 183 0.001 body mass (VT:0001259) body weight (CMO:0000012) 8 43296169 98968765 Rat 1300177 Cm2 Cardiac mass QTL 2 3.65 heart mass (VT:0007028) heart weight (CMO:0000017) 8 54259986 100382532 Rat 1549908 Neudeg1 Neurodegradation QTL 1 5.5 0 nervous system integrity trait (VT:0010566) logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986) 8 30188867 94457446 Rat 12879879 Cm99 Cardiac mass QTL 99 0.001 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 8 43296169 98968765 Rat 2313067 Bss77 Bone structure and strength QTL 77 3.1 0.0001 tibia size trait (VT:0100001) tibia midshaft endosteal cross-sectional area (CMO:0001716) 8 30848154 82460899 Rat 12879880 Cm100 Cardiac mass QTL 100 0.001 heart left ventricle mass (VT:0007031) heart left ventricle weight to body weight ratio (CMO:0000530) 8 43296169 98968765 Rat 12879881 Cm101 Cardiac mass QTL 101 0.001 heart right ventricle mass (VT:0007033) heart right ventricle weight to body weight ratio (CMO:0000914) 8 43296169 98968765 Rat 12879882 Am8 Aortic mass QTL 8 0.001 aorta mass (VT:0002845) aorta weight to aorta length to body weight ratio (CMO:0002722) 8 43296169 98968765 Rat 12879883 Kidm65 Kidney mass QTL 65 0.001 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 8 43296169 98968765 Rat 1358912 Bw51 Body weight QTL 51 2.95 body mass (VT:0001259) body weight (CMO:0000012) 8 51351728 107062046 Rat 2313086 Bss60 Bone structure and strength QTL 60 4.1 0.0001 tibia length (VT:0004357) tibia length (CMO:0000450) 8 50095249 82460899 Rat 1558646 Swd5 Spike wave discharge measurement QTL 5 3.45 0.00036 brain electrophysiology trait (VT:0010557) brain spike-and-wave discharge frequency (CMO:0001742) 8 14906751 59906751 Rat 2293697 Bmd39 Bone mineral density QTL 39 femur strength trait (VT:0010010) femur total energy absorbed before break (CMO:0001677) 8 54043744 98968765 Rat 631648 Stl5 Serum triglyceride level QTL 5 4 0.0003 blood triglyceride amount (VT:0002644) plasma triglyceride level (CMO:0000548) 8 27205715 54998217 Rat 1331837 Bw23 Body weight QTL 23 4.19 0.00007 body mass (VT:0001259) body weight (CMO:0000012) 8 46531722 99083736 Rat 1331838 Niddm61 Non-insulin dependent diabetes mellitus QTL 61 3.53 0.0004 blood insulin amount (VT:0001560) plasma insulin level (CMO:0000342) 8 36469535 99083736 Rat 631650 Stl6 Serum triglyceride level QTL 6 4 0.0019 blood triglyceride amount (VT:0002644) plasma triglyceride level (CMO:0000548) 8 10378157 112202585 Rat 1581557 Eae16 Experimental allergic encephalomyelitis QTL 16 3.8 nervous system integrity trait (VT:0010566) experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046) 8 8462195 110921472 Rat 631271 Lecl1 Lens clarity QTL 1 0.001 lens clarity trait (VT:0001304) age of onset/diagnosis of cataract (CMO:0001584) 8 18984168 84531599 Rat 2303564 Gluco43 Glucose level QTL 43 3 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 8 26130187 71130187 Rat 2303570 Gluco48 Glucose level QTL 48 2 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 8 49805831 94805831 Rat 2313046 Bss78 Bone structure and strength QTL 78 3.5 0.0001 tibia strength trait (VT:1000284) tibia total energy absorbed before break (CMO:0001736) 8 30848154 82460899 Rat 2303572 Insul13 Insulin level QTL 13 2 blood insulin amount (VT:0001560) blood insulin level (CMO:0000349) 8 26130187 71130187 Rat 2301402 Bp316 Blood pressure QTL 316 0.005 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 8 53968765 98968765 Rat 631664 Hcar3 Hepatocarcinoma resistance QTL 3 2.9 0.0005 liver integrity trait (VT:0010547) volume of individual liver tumorous lesion (CMO:0001078) 8 54237644 99103503 Rat
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
10
49
107
91
90
59
25
59
6
217
96
87
45
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31
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Ensembl Acc Id:
ENSRNOT00000038830 ⟹ ENSRNOP00000034357
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 8 54,414,457 - 54,455,547 (-) Ensembl Rnor_6.0 Ensembl 8 58,602,127 - 58,647,933 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000112944 ⟹ ENSRNOP00000083007
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 8 54,414,618 - 54,500,079 (-) Ensembl
RefSeq Acc Id:
NM_001399312 ⟹ NP_001386241
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 8 63,309,683 - 63,351,687 (-) NCBI mRatBN7.2 8 54,413,503 - 54,455,512 (-) NCBI
RefSeq Acc Id:
XM_039082372 ⟹ XP_038938300
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 8 63,309,683 - 63,316,716 (-) NCBI mRatBN7.2 8 54,413,503 - 54,421,114 (-) NCBI
Ensembl Acc Id:
ENSRNOP00000034357 ⟸ ENSRNOT00000038830
RefSeq Acc Id:
XP_038938300 ⟸ XM_039082372
- Peptide Label:
isoform X1
- UniProtKB:
A0A8I5ZYA0 (UniProtKB/TrEMBL)
Ensembl Acc Id:
ENSRNOP00000083007 ⟸ ENSRNOT00000112944
RefSeq Acc Id:
NP_001386241 ⟸ NM_001399312
- UniProtKB:
F1LX20 (UniProtKB/TrEMBL), A6J4K3 (UniProtKB/TrEMBL), A0A8I5ZYA0 (UniProtKB/TrEMBL)
RGD ID: 13695978
Promoter ID: EPDNEW_R6500
Type: multiple initiation site
Name: Tnfaip8l3_1
Description: TNF alpha induced protein 8 like 3
SO ACC ID: SO:0000170
Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ )
Experiment Methods: Single-end sequencing.
Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 8 58,647,927 - 58,647,987 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2015-12-02
Tnfaip8l3
TNF alpha induced protein 8 like 3
Tnfaip8l3
tumor necrosis factor, alpha-induced protein 8-like 3
Nomenclature updated to reflect human and mouse nomenclature
1299863
APPROVED
2008-04-30
Tnfaip8l3
tumor necrosis factor, alpha-induced protein 8-like 3
Tnfaip8l3_predicted
tumor necrosis factor, alpha-induced protein 8-like 3 (predicted)
'predicted' is removed
2292626
APPROVED
2006-03-30
Tnfaip8l3_predicted
tumor necrosis factor, alpha-induced protein 8-like 3 (predicted)
RGD1311533_predicted
similar to TNF-induced protein (predicted)
Symbol and Name updated
1299863
APPROVED
2005-01-20
RGD1311533_predicted
similar to TNF-induced protein (predicted)
LOC315673_predicted
Symbol and Name status set to approved
1331353
APPROVED
2005-01-12
LOC315673_predicted
similar to TNF-induced protein (predicted)
Symbol and Name status set to provisional
70820
PROVISIONAL