Cm3 QTL Report (Rattus norvegicus) - Rat Genome Database
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QTL: Cm3 (Cardiac mass QTL 3) Rattus norvegicus

Symbol: Cm3
Name: Cardiac mass QTL 3
RGD ID: 1300150
Also known as: Specialized Center of Research QTL 117; SCOR117
Trait: heart mass   (VT:0007028)    
Measurement Type: heart weight to body weight ratio   (CMO:0000074)    
LOD Score: 3.97
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0858,425,679 - 59,716,199RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0857,006,953 - 58,297,648RGDRnor5.0
RGSC_v3.4857,308,742 - 58,692,901RGDRGSC3.4
RGSC_v3.1857,327,796 - 58,711,961RGD
Cross Type: Not Available
Strains Crossed: BN/SsNHsd SS/JrHsdMcwi 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
Cardiomegaly  (IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait
heart mass  (IDA)

Rat Strain
BN/SsNHsd  (IEA)
SS/JrHsdMcwi  (IEA)

References

References - curated
1. Moreno C, etal., Physiol Genomics 2003 Nov 11;15(3):243-57. Epub 2003 Oct 07.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
70889Idh3aisocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha85916460159183899Rat
61846Psma4proteasome 20S subunit alpha 485953245659539916Rat
2347Chrna5cholinergic receptor nicotinic alpha 5 subunit85956181759590172Rat
2351Chrnb4cholinergic receptor nicotinic beta 4 subunit85961048959629073Rat
2345Chrna3cholinergic receptor nicotinic alpha 3 subunit85959400759607122Rat
727879Gldngliomedin85887051658914605Rat
621539Ireb2iron responsive element binding protein 285945097459503634Rat
2400Crabp1cellular retinoic acid binding protein 185934409759352135Rat
2457Cyp19a1cytochrome P450, family 19, subfamily a, polypeptide 185874484958772408Rat
1308677Hykkhydroxylysine kinase85950797559531745Rat
1305224Slnsarcolipin85843140758435654Rat
1311533Tnfaip8l3TNF alpha induced protein 8 like 385859938258648045Rat
1309791Sh2d7SH2 domain containing 785911085959122974Rat
1308718Cib2calcium and integrin binding family member 285912307859139946Rat
1307680Ube2q2ubiquitin conjugating enzyme E2 Q285970997259754102Rat
1308228Wdr61WD repeat domain 6185929633959313663Rat
1310035Dnaja4DnaJ heat shock protein family (Hsp40) member A485927826259294003Rat
1564186Elmod1ELMO domain containing 185848607858542884Rat
1586163Dmxl2Dmx-like 285893257559077788Rat
708557Acsbg1acyl-CoA synthetase bubblegum family member 185918411159240133Rat
1596097LOC690408similar to brain zinc finger protein85957679359579231Rat
6501631LOC10090981660S ribosomal protein L37a-like85884426358844848Rat
7571014LOC102553052uncharacterized LOC10255305285882904858841358Rat
7556443LOC102553335polypyrimidine tract-binding protein 1-like85895737358962978Rat
7674992LOC102552978uncharacterized LOC10255297885875044658755531Rat
9399090LOC103693097uncharacterized LOC10369309785874187358745420Rat
11462771LOC108351710glyceraldehyde-3-phosphate dehydrogenase-like85903932159040531Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10354D8Bord123085960754159607770Ratregion
33880D8Mit1212485908735959087488Ratregion
36161D8Rat3617085842551058425679Ratregion
40544D8Rat15539085926332659263704Ratregion
42223D8Arb1239085877194958772399Ratregion
41454D8Rat14913985971619959716349Ratregion
41472D8Rat15620185853357558533797Ratregion
44423D8Got8617485938315459383259Ratregion
44423D8Got8617485938308659383259Ratregion
44425D8Got8325985952046859520718Ratregion
44426D8Got8526285914271359142974Ratregion
1631160D8Wox3016585960754359607707Ratregion
1631837D8Wox1685877214958772365Ratregion
1634113D8Wox2922685960946959609694Ratregion
7192338Crabp165485934423659344889Ratregion
7193074Chrnb422785960987059610097Ratregion
5036125Crabp117385934478759344959Ratregion
5038884RH12738822085843571258435931Ratregion
5035528Clom27185891367058913940Ratregion
5027383AV35821311185929451959294629Ratregion
5035254AA87502510985935192159352029Ratregion
5025350RH12797520585918351859183722Ratregion
5056357RH14433118985950086059501048Ratregion
5053801RH14285824285919275659192997Ratregion
5053961RH14295022185950289059503110Ratregion
5048684RH13304620185874471258744912Ratregion
5047608RH13242521785918428059184496Ratregion
5049580RH13356221685912311159123326Ratregion
5043468RH13004220485953961059539813Ratregion
5041464RH12887118785874680458746990Ratregion
5072530RH13690320985848628858486496Ratregion
5066390AU04838520885946691659467123Ratregion
5064936BE10872121185959371859593928Ratregion
5066462AU04834213285936809959368230Ratregion
5066518AU04830912885953138059531507Ratregion
5061590BF39677123585928453959284773Ratregion
5086961BQ19412716085909478059094939Ratregion
5086119Chrnb422785961538359616969Ratregion
5087556PMC312758P410585962935759629461Ratregion
5090521AU04980118485916297059163153Ratregion
5085183AA79957014885929418359294330Ratregion
5086596Chrna510485958949659589599Ratregion
5086697AA95745110185918298759183087Ratregion
5502699IREB248785949084659491332Ratregion
5504944AY07488738585953208059532464Ratregion
5506025UniSTS:49748482585920303059203854Ratregion
5500013UniSTS:23613726485929426359294526Ratregion
5502347RH1245608285918300559183086Ratregion
Position Markers

Flank 1: (D8Rat149)
Rat AssemblyChrPosition (strand)Source
Rnor_6.0859,716,199 - 59,716,349NCBI
Rnor_5.0858,297,648 - 58,297,798UniSTS
RGSC_v3.4858,692,907 - 58,693,057UniSTS
RGSC_v3.4858,692,901 - 58,693,265RGD
RGSC_v3.1858,711,961 - 58,712,111RGD
Celera855,008,447 - 55,008,597UniSTS
Cytogenetic Map8q24UniSTS
RH 3.4 Map8614.2RGD
RH 3.4 Map8614.2UniSTS
RH 2.0 Map8480.2RGD
SHRSP x BN Map840.33RGD
Peak: (D8Rat159)
Rat AssemblyChrPosition (strand)Source
RH 3.4 Map8458.3RGD
RH 3.4 Map8458.3UniSTS
RH 2.0 Map8373.8RGD
SHRSP x BN Map835.78RGD
Flank 2: (D8Rat36)
Rat AssemblyChrPosition (strand)Source
Rnor_6.0858,425,510 - 58,425,679NCBI
Rnor_5.0857,006,784 - 57,006,953UniSTS
RGSC_v3.4857,308,573 - 57,308,742UniSTS
RGSC_v3.4857,308,572 - 57,308,742RGD
RGSC_v3.1857,327,627 - 57,327,796RGD
RH 3.4 Map8589.1UniSTS
RH 3.4 Map8589.1RGD
RH 2.0 Map8457.2RGD
SHRSP x BN Map841.2RGD
FHH x ACI Map848.36RGD


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)89531047119211942Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810938911120496129Rat
1558646Swd5Spike wave discharge measurement QTL 53.450.00036brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)81766655562666555Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)82071759265717592Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)82146491991140553Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)821813070100873963Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)82784149672841496Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)82986798359908353Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)829867983106526740Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)829867983106526740Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)829867983106526740Rat
2303564Gluco43Glucose level QTL 433blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)83014480075144800Rat
2303572Insul13Insulin level QTL 132blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)83014480075144800Rat
1331804Cm30Cardiac mass QTL 303.77443heart mass (VT:0007028)heart wet weight (CMO:0000069)83091811258858224Rat
1300146Rf17Renal function QTL 172.9renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)83091811275918112Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)830918112107206309Rat
724514Uae15Urinary albumin excretion QTL 152.9urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)83220198175971421Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)832888352101374135Rat
1331744Bp217Blood pressure QTL 2173.398arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83355866062857995Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83355866065717592Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83355866065717592Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83355866065717592Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83355866065717592Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83355866065717592Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83355866065717592Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83355866089058369Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83355866089058369Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83355866089058369Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83355866089058369Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)833558660109028082Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)833558660109028082Rat
1578755Pur5Proteinuria QTL 53.30.0001total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)833558660109028082Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)833558764113580387Rat
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83504141480041414Rat
1582222Epfw2Epididymal fat weight QTL 23.20.0005epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)83592559480925594Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)839230130106506973Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83992790184927901Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83995802284958022Rat
737824Hcar10Hepatocarcinoma resistance QTL 102.9liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)84421919789542960Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)844219197100873963Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)844458129118087517Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)84571234480003418Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84571234490712344Rat
631216Stl9Serum triglyceride level QTL 94.710.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)84571247575971259Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84658843796998640Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)847200750106394378Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)847200750106394378Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)847200750106394378Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)847200750106394378Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)847200750106394378Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)847200750106394378Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)850529480128036471Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)850529480128036471Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)850529480128036471Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)850529480128036471Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)850529563106506973Rat
2313086Bss60Bone structure and strength QTL 604.10.0001tibia length (VT:0004357)tibia length (CMO:0000450)85406504489058369Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85406504489058369Rat
5684973Bss100Bone structure and strength QTL 1004.7tibia area (VT:1000281)tibia area measurement (CMO:0001382)85406504489058369Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)855435004115812386Rat
2303570Gluco48Glucose level QTL 482blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)855659105100659105Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)858230766106394378Rat
1582243Bw66Body weight QTL 663.40.0048body mass (VT:0001259)body weight (CMO:0000012)85842551091990535Rat
1582254Kidm31Kidney mass QTL 313kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)85842551091990535Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)858425510106526740Rat
1300150Cm3Cardiac mass QTL 33.97heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)85842567959716199Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)859234112108068306Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Cm3

RGD Curation Notes
Note Type Note Reference
qtl_general additional information, including phenotype and mapping information, can be found at Genomic Map of Cardiovascular Phenotypes 727992
qtl_general heart weight in grams divided by body weight 727992