Cgas (cyclic GMP-AMP synthase) - Rat Genome Database

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Gene: Cgas (cyclic GMP-AMP synthase) Rattus norvegicus
Analyze
Symbol: Cgas
Name: cyclic GMP-AMP synthase
RGD ID: 1586939
Description: Predicted to enable several functions, including 2',3'-cyclic GMP-AMP synthase activity; molecular condensate scaffold activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in several processes, including cyclic-nucleotide-mediated signaling; defense response to symbiont; and regulation of defense response. Predicted to act upstream of or within several processes, including determination of adult lifespan; regulation of T cell activation; and regulation of gene expression. Predicted to be located in nuclear body; plasma membrane; and site of double-strand break. Predicted to be active in cytosol and nucleus. Orthologous to human CGAS (cyclic GMP-AMP synthase); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC682147; Mab-21 domain containing 1; Mb21d1; similar to CG7194-PA
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8888,172,559 - 88,187,538 (-)NCBIGRCr8
mRatBN7.2879,292,282 - 79,306,998 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl879,294,511 - 79,305,496 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0885,789,515 - 85,804,008 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl885,789,763 - 85,803,433 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0885,344,976 - 85,353,236 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera879,042,110 - 79,053,035 (-)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
cytosol  (IBA,ISO)
nuclear body  (IEA,ISO)
nucleoplasm  (ISO)
nucleus  (IBA,ISO)
plasma membrane  (ISO)
site of double-strand break  (IBA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21478870   PMID:23258412   PMID:23258413   PMID:23929945   PMID:24077100   PMID:26046437   PMID:26300263   PMID:26371324   PMID:26829768   PMID:28214358   PMID:28363908   PMID:28738408  
PMID:28759028   PMID:28759889   PMID:28934246   PMID:28963528   PMID:29937271   PMID:30007416   PMID:30356214   PMID:30827685   PMID:33879372   PMID:34477314   PMID:35926582   PMID:36878046  


Genomics

Comparative Map Data
Cgas
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8888,172,559 - 88,187,538 (-)NCBIGRCr8
mRatBN7.2879,292,282 - 79,306,998 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl879,294,511 - 79,305,496 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0885,789,515 - 85,804,008 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl885,789,763 - 85,803,433 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0885,344,976 - 85,353,236 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera879,042,110 - 79,053,035 (-)NCBICelera
Cytogenetic Map8q31NCBI
CGAS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38673,423,711 - 73,452,297 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl673,413,515 - 73,452,297 (-)EnsemblGRCh38hg38GRCh38
GRCh37674,133,434 - 74,162,020 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36674,191,577 - 74,218,764 (-)NCBINCBI36Build 36hg18NCBI36
Build 34674,191,313 - 74,218,720NCBI
Celera674,529,415 - 74,556,286 (-)NCBICelera
Cytogenetic Map6q13NCBI
HuRef671,333,337 - 71,360,196 (-)NCBIHuRef
CHM1_1674,301,681 - 74,328,872 (-)NCBICHM1_1
T2T-CHM13v2.0674,600,410 - 74,628,713 (-)NCBIT2T-CHM13v2.0
Cgas
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39978,337,800 - 78,350,519 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl978,337,808 - 78,350,519 (-)EnsemblGRCm39 Ensembl
GRCm38978,430,518 - 78,443,237 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl978,430,526 - 78,443,237 (-)EnsemblGRCm38mm10GRCm38
MGSCv37978,278,325 - 78,290,954 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36978,217,019 - 78,228,921 (-)NCBIMGSCv36mm8
Celera975,608,705 - 75,621,402 (-)NCBICelera
Cytogenetic Map9E1NCBI
cM Map943.65NCBI
Cgas
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554938,593,104 - 8,607,297 (-)NCBIChiLan1.0ChiLan1.0
CGAS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2593,404,484 - 93,435,310 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1691,329,355 - 91,359,775 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0671,252,050 - 71,279,121 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1674,542,994 - 74,567,107 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl674,544,251 - 74,566,965 (-)Ensemblpanpan1.1panPan2
CGAS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11235,511,920 - 35,528,759 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1235,512,860 - 35,528,596 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1235,380,775 - 35,399,989 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01236,066,175 - 36,085,892 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1236,066,172 - 36,085,743 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11235,605,589 - 35,625,008 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01235,627,370 - 35,646,829 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01235,751,269 - 35,770,689 (-)NCBIUU_Cfam_GSD_1.0
Cgas
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494670,802,542 - 70,812,760 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936859797,469 - 807,036 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CGAS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl192,483,327 - 92,504,307 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1192,483,253 - 92,500,376 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21103,536,112 - 103,553,221 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CGAS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1171,697,446 - 1,723,626 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl171,697,775 - 1,723,472 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660587,609,831 - 7,638,092 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cgas
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624819643,045 - 680,684 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624819587,739 - 680,618 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cgas
61 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:117
Count of miRNA genes:90
Interacting mature miRNAs:101
Transcripts:ENSRNOT00000073286
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
737824Hcar10Hepatocarcinoma resistance QTL 102.9liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)84071306682925667Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)85423764499103503Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85009524982460899Rat
5684973Bss100Bone structure and strength QTL 1004.7tibia area (VT:1000281)tibia area measurement (CMO:0001382)85009524982460899Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)87531193882925521Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83646953599083736Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)854259986100382532Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)83018886794457446Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84071306693965294Rat
1582254Kidm31Kidney mass QTL 313kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)85423764485365202Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
2303570Gluco48Glucose level QTL 482blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)84980583194805831Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)84329616998968765Rat
1582243Bw66Body weight QTL 663.40.0048body mass (VT:0001259)body weight (CMO:0000012)85423764485365202Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)84653172299083736Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)87531177784531599Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)82720571599103503Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83555193880551938Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)84329616998968765Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)82720571599103503Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)851351728107062046Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83084815482460899Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)85404374498968765Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83084815482460899Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83084815482460899Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)84329616998968765Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)84329616998968765Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)84329616998968765Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)84329616998968765Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83084815482460899Rat
2313086Bss60Bone structure and strength QTL 604.10.0001tibia length (VT:0004357)tibia length (CMO:0000450)85009524982460899Rat

Markers in Region
BI276780  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2879,295,017 - 79,295,127 (+)MAPPERmRatBN7.2
Rnor_6.0885,789,554 - 85,789,663NCBIRnor6.0
Rnor_5.0885,342,984 - 85,343,093UniSTSRnor5.0
Celera879,042,149 - 79,042,258UniSTS
RH 3.4 Map8923.9UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 3 38 50 34 19 34 2 2 49 35 34 11 2
Below cutoff 5 7 7 7 6 9 25 4 6

Sequence


RefSeq Acc Id: ENSRNOT00000073286   ⟹   ENSRNOP00000065782
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl879,297,377 - 79,305,496 (-)Ensembl
Rnor_6.0 Ensembl885,795,523 - 85,803,433 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000081544   ⟹   ENSRNOP00000069428
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl879,294,511 - 79,305,496 (-)Ensembl
Rnor_6.0 Ensembl885,789,763 - 85,803,433 (-)Ensembl
RefSeq Acc Id: XM_039082530   ⟹   XP_038938458
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8888,172,559 - 88,187,538 (-)NCBI
mRatBN7.2879,292,282 - 79,306,998 (-)NCBI
RefSeq Acc Id: XM_039082531   ⟹   XP_038938459
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8888,177,789 - 88,187,538 (-)NCBI
mRatBN7.2879,297,506 - 79,306,994 (-)NCBI
Protein Sequences
Protein RefSeqs XP_038938458 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938459 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000065782.2
  ENSRNOP00000069428
  ENSRNOP00000069428.2
RefSeq Acc Id: ENSRNOP00000065782   ⟸   ENSRNOT00000073286
RefSeq Acc Id: ENSRNOP00000069428   ⟸   ENSRNOT00000081544
RefSeq Acc Id: XP_038938458   ⟸   XM_039082530
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JVC4 (UniProtKB/TrEMBL),   A6I1J6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938459   ⟸   XM_039082531
- Peptide Label: isoform X2
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JVC4-F1-model_v2 AlphaFold A0A0G2JVC4 1-510 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1586939 AgrOrtholog
BioCyc Gene G2FUF-29757 BioCyc
Ensembl Genes ENSRNOG00000046191 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000073286.2 UniProtKB/TrEMBL
  ENSRNOT00000081544.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1410.40 UniProtKB/TrEMBL
  3.30.460.90 UniProtKB/TrEMBL
InterPro Mab-21-like_nuc_Trfase UniProtKB/TrEMBL
  Mab-21_dom UniProtKB/TrEMBL
  Mab-21_HhH/H2TH-like UniProtKB/TrEMBL
NCBI Gene 682147 ENTREZGENE
PANTHER CELL FATE DETERMINING PROTEIN MAB21-RELATED UniProtKB/TrEMBL
  CYCLIC GMP-AMP SYNTHASE UniProtKB/TrEMBL
Pfam Mab-21 UniProtKB/TrEMBL
  Mab-21_C UniProtKB/TrEMBL
PhenoGen Cgas PhenoGen
RatGTEx ENSRNOG00000046191 RatGTEx
SMART Mab-21 UniProtKB/TrEMBL
UniProt A0A0G2JVC4 ENTREZGENE, UniProtKB/TrEMBL
  A6I1J6 ENTREZGENE, UniProtKB/TrEMBL
  M0R8I6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-10-30 Cgas  cyclic GMP-AMP synthase  Mb21d1  Mab-21 domain containing 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-13 Mb21d1  Mab-21 domain containing 1  LOC682147  similar to CG7194-PA  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC682147  similar to CG7194-PA      Symbol and Name status set to provisional 70820 PROVISIONAL