Gene: Cgas (cyclic GMP-AMP synthase) Rattus norvegicus
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Symbol: Cgas
Name: cyclic GMP-AMP synthase
Description: ENCODES a protein that exhibits chromatin binding (ortholog); cyclic-GMP-AMP synthase activity (ortholog); DNA binding (ortholog); INVOLVED IN activation of innate immune response (ortholog); cellular response to DNA damage stimulus (ortholog); cellular response to exogenous dsRNA (ortholog); FOUND IN cytosol (ortholog); nucleus (ortholog); site of double-strand break (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; bisphenol A
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC682147; Mab-21 domain containing 1; Mb21d1; similar to CG7194-PA
Orthologs:
Homo sapiens (human) : CGAS (cyclic GMP-AMP synthase)  HGNC  Alliance
Mus musculus (house mouse) : Cgas (cyclic GMP-AMP synthase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cgas (cyclic GMP-AMP synthase)
Pan paniscus (bonobo/pygmy chimpanzee) : CGAS (cyclic GMP-AMP synthase)
Canis lupus familiaris (dog) : CGAS (cyclic GMP-AMP synthase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cgas (cyclic GMP-AMP synthase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0885,789,515 - 85,804,008 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0885,344,976 - 85,353,236 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera879,042,110 - 79,053,035 (-)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Cgas
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1586939
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2018-09-11
Status: ACTIVE