Aqp9 (aquaporin 9) - Rat Genome Database

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Gene: Aqp9 (aquaporin 9) Rattus norvegicus
Analyze
Symbol: Aqp9
Name: aquaporin 9
RGD ID: 68433
Description: Exhibits water channel activity. Involved in canalicular bile acid transport and water transport. Localizes to basolateral plasma membrane and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in kidney disease. Orthologous to human AQP9 (aquaporin 9); PARTICIPATES IN water transport pathway; bile acid transport pathway; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: AQP-9; aquaglyceroporin-9; aquaporin-9; MGC93419; neutral solute channel aquaporin 9
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2871,797,231 - 71,837,485 (-)NCBI
Rnor_6.0 Ensembl877,559,624 - 77,599,781 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0877,559,621 - 77,599,781 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0875,483,006 - 75,523,423 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4875,611,485 - 75,651,646 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1875,630,541 - 75,670,700 (-)NCBI
Celera869,899,442 - 69,939,523 (+)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-demecolcine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,4,7,8-Pentachlorodibenzofuran  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-hydroxypropanoic acid  (EXP,ISO)
3-hydroxybutyric acid  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-azacytidine  (ISO)
5-fluorouracil  (EXP)
6-propyl-2-thiouracil  (EXP)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (ISO)
acetamide  (EXP)
adenine  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
androstane-3,17-diol  (EXP)
antimony(0)  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP)
buta-1,3-diene  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (ISO)
cholesterol  (ISO)
choline  (ISO)
cobalt atom  (ISO)
cyclosporin A  (ISO)
D-glucitol  (EXP,ISO)
D-mannitol  (EXP)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dieldrin  (EXP)
diprotium oxide  (EXP,ISO)
endosulfan  (ISO)
fenofibrate  (ISO)
fipronil  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
genistein  (EXP)
glycerol  (EXP,ISO)
heptachlor  (EXP)
indirubin-3'-monoxime  (ISO)
isoflavones  (EXP)
L-methionine  (ISO)
lamivudine  (ISO)
lonidamine  (EXP)
LY294002  (ISO)
mercury atom  (EXP)
mercury dichloride  (EXP,ISO)
mercury(0)  (EXP)
mirex  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP)
nickel sulfate  (ISO)
nigericin  (ISO)
O-methyleugenol  (ISO)
orphenadrine  (EXP)
oxaliplatin  (EXP)
ozone  (EXP)
paracetamol  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
phenformin  (EXP)
phloretin  (EXP,ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP,ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
quercetin  (EXP)
rac-lactic acid  (EXP,ISO)
selenic acid  (ISO)
selenous acid  (ISO)
serpentine asbestos  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
streptozocin  (EXP)
styrene  (EXP)
tamoxifen  (ISO)
Tanshinone I  (ISO)
Tesaglitazar  (EXP)
testosterone  (ISO)
tetrachloromethane  (EXP)
thiourea  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
triphenyl phosphate  (EXP)
triptonide  (ISO)
troglitazone  (EXP,ISO)
Tungsten carbide  (ISO)
undecane  (EXP)
urea  (EXP,ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
vitamin D  (ISO)
water  (EXP,ISO)
zidovudine  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:1373524   PMID:1510932   PMID:7530250   PMID:9369468   PMID:9405233   PMID:9514918   PMID:9806845   PMID:9829975   PMID:10205677   PMID:10318966   PMID:10510269   PMID:10564231  
PMID:11001937   PMID:11034202   PMID:11076974   PMID:11573934   PMID:11972053   PMID:12084581   PMID:12477932   PMID:12594337   PMID:12944406   PMID:14701836   PMID:15489334   PMID:15647391  
PMID:15850448   PMID:15948717   PMID:16446030   PMID:16596446   PMID:16857339   PMID:17178220   PMID:17337204   PMID:17525633   PMID:17636236   PMID:18053968   PMID:18055461   PMID:18202181  
PMID:18501347   PMID:18511455   PMID:18669624   PMID:18718702   PMID:18762715   PMID:19115411   PMID:19193945   PMID:19399395   PMID:19429018   PMID:19948840   PMID:20357197   PMID:20958229  
PMID:21208160   PMID:21251984   PMID:21851171   PMID:22114114   PMID:23040263   PMID:23415870   PMID:23464865   PMID:23506846   PMID:24828425   PMID:25479407   PMID:25604497   PMID:25903824  
PMID:29523003   PMID:30017933   PMID:30266683   PMID:30420639   PMID:31218464   PMID:31533210   PMID:31746418  


Genomics

Comparative Map Data
Aqp9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2871,797,231 - 71,837,485 (-)NCBI
Rnor_6.0 Ensembl877,559,624 - 77,599,781 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0877,559,621 - 77,599,781 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0875,483,006 - 75,523,423 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4875,611,485 - 75,651,646 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1875,630,541 - 75,670,700 (-)NCBI
Celera869,899,442 - 69,939,523 (+)NCBICelera
Cytogenetic Map8q24NCBI
AQP9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1558,138,169 - 58,185,911 (+)EnsemblGRCh38hg38GRCh38
GRCh381558,138,169 - 58,185,911 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371558,430,368 - 58,478,110 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361556,217,700 - 56,265,402 (+)NCBINCBI36hg18NCBI36
Build 341556,217,770 - 56,265,401NCBI
Celera1535,319,964 - 35,368,212 (+)NCBI
Cytogenetic Map15q21.3NCBI
HuRef1535,253,376 - 35,301,102 (+)NCBIHuRef
CHM1_11558,548,344 - 58,596,089 (+)NCBICHM1_1
Aqp9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39971,017,941 - 71,075,170 (-)NCBIGRCm39mm39
GRCm39 Ensembl971,017,941 - 71,075,964 (-)Ensembl
GRCm38971,110,659 - 71,167,849 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl971,110,659 - 71,168,682 (-)EnsemblGRCm38mm10GRCm38
MGSCv37970,958,468 - 71,011,096 (-)NCBIGRCm37mm9NCBIm37
MGSCv36970,909,221 - 70,961,849 (-)NCBImm8
Celera968,318,271 - 68,366,608 (-)NCBICelera
Cytogenetic Map9DNCBI
Aqp9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545016,253,571 - 16,302,657 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545016,253,706 - 16,346,602 (-)NCBIChiLan1.0ChiLan1.0
AQP9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11555,418,767 - 55,466,541 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1555,418,767 - 55,466,541 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01537,107,061 - 37,154,887 (+)NCBIMhudiblu_PPA_v0panPan3
AQP9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13023,223,413 - 23,271,893 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3023,225,331 - 23,269,076 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3023,195,554 - 23,244,048 (+)NCBI
ROS_Cfam_1.03023,381,591 - 23,430,109 (+)NCBI
UMICH_Zoey_3.13023,314,125 - 23,361,613 (+)NCBI
UNSW_CanFamBas_1.03023,398,650 - 23,446,048 (+)NCBI
UU_Cfam_GSD_1.03023,540,476 - 23,589,012 (+)NCBI
Aqp9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640101,473,023 - 101,514,878 (+)NCBI
SpeTri2.0NW_00493647119,321,366 - 19,361,227 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AQP9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1113,765,680 - 113,848,685 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11113,798,380 - 113,848,452 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21125,897,935 - 125,959,201 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AQP9
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12625,326,108 - 25,374,743 (-)NCBI
ChlSab1.1 Ensembl2625,326,087 - 25,373,336 (-)Ensembl
Aqp9
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478113,650,612 - 13,691,175 (-)NCBI

Position Markers
RH141275  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0877,559,767 - 77,559,972NCBIRnor6.0
Rnor_5.0875,523,072 - 75,523,277UniSTSRnor5.0
RGSC_v3.4875,611,631 - 75,611,836UniSTSRGSC3.4
Celera869,939,172 - 69,939,377UniSTS
Cytogenetic Map8q24UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)89531047119211942Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810938911120496129Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)82146491991140553Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)821813070100873963Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)829867983106526740Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)829867983106526740Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)829867983106526740Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)830918112107206309Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)832888352101374135Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83355866089058369Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83355866089058369Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83355866089058369Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83355866089058369Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)833558660109028082Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)833558660109028082Rat
1578755Pur5Proteinuria QTL 53.30.0001total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)833558660109028082Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)833558764113580387Rat
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83504141480041414Rat
1582222Epfw2Epididymal fat weight QTL 23.20.0005epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)83592559480925594Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)839230130106506973Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83992790184927901Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83995802284958022Rat
737824Hcar10Hepatocarcinoma resistance QTL 102.9liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)84421919789542960Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)844219197100873963Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)844458129118087517Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)84571234480003418Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84571234490712344Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84658843796998640Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)847200750106394378Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)847200750106394378Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)847200750106394378Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)847200750106394378Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)847200750106394378Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)847200750106394378Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)850529480128036471Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)850529480128036471Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)850529480128036471Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)850529480128036471Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)850529563106506973Rat
2313086Bss60Bone structure and strength QTL 604.10.0001tibia length (VT:0004357)tibia length (CMO:0000450)85406504489058369Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85406504489058369Rat
5684973Bss100Bone structure and strength QTL 1004.7tibia area (VT:1000281)tibia area measurement (CMO:0001382)85406504489058369Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)855435004115812386Rat
2303570Gluco48Glucose level QTL 482blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)855659105100659105Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)858230766106394378Rat
1582243Bw66Body weight QTL 663.40.0048body mass (VT:0001259)body weight (CMO:0000012)85842551091990535Rat
1582254Kidm31Kidney mass QTL 313kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)85842551091990535Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)858425510106526740Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)859234112108068306Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)861394378106394378Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)861394378106394378Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)865717449128033050Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)872849686117849686Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight as a percentage of body weight (CMO:0000654)874917593121080545Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)876103982127182642Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:200
Count of miRNA genes:145
Interacting mature miRNAs:158
Transcripts:ENSRNOT00000021442
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 41 41 41 1 8
Low 2 8 17 2 2 26 2 24 11 2
Below cutoff 1 16 7 2 5 6 17 32 9 5

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_022960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC114842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF016406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC085731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000087980   ⟹   ENSRNOP00000069377
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl877,559,624 - 77,599,781 (-)Ensembl
RefSeq Acc Id: NM_022960   ⟹   NP_075249
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2871,797,231 - 71,837,395 (-)NCBI
Rnor_6.0877,559,621 - 77,599,781 (-)NCBI
Rnor_5.0875,483,006 - 75,523,423 (+)NCBI
RGSC_v3.4875,611,485 - 75,651,646 (-)RGD
Celera869,899,442 - 69,939,523 (+)RGD
Sequence:
RefSeq Acc Id: XM_006243362   ⟹   XP_006243424
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2871,797,231 - 71,837,485 (-)NCBI
Rnor_6.0877,559,621 - 77,598,767 (-)NCBI
Rnor_5.0875,483,006 - 75,523,423 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008766336   ⟹   XP_008764558
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2871,797,231 - 71,833,976 (-)NCBI
Rnor_6.0877,559,621 - 77,594,559 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039082095   ⟹   XP_038938023
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2871,797,231 - 71,837,485 (-)NCBI
RefSeq Acc Id: XM_039082096   ⟹   XP_038938024
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2871,797,231 - 71,836,728 (-)NCBI
RefSeq Acc Id: XM_039082097   ⟹   XP_038938025
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2871,797,231 - 71,837,485 (-)NCBI
RefSeq Acc Id: XM_039082098   ⟹   XP_038938026
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2871,797,231 - 71,833,976 (-)NCBI
RefSeq Acc Id: XM_039082099   ⟹   XP_038938027
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2871,797,231 - 71,837,485 (-)NCBI
RefSeq Acc Id: XM_039082100   ⟹   XP_038938028
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2871,797,231 - 71,836,728 (-)NCBI
RefSeq Acc Id: XM_039082101   ⟹   XP_038938029
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2871,800,868 - 71,833,983 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_075249   ⟸   NM_022960
- UniProtKB: P56627 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006243424   ⟸   XM_006243362
- Peptide Label: isoform X1
- UniProtKB: P56627 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008764558   ⟸   XM_008766336
- Peptide Label: isoform X1
- UniProtKB: P56627 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000069377   ⟸   ENSRNOT00000087980
RefSeq Acc Id: XP_038938025   ⟸   XM_039082097
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038938023   ⟸   XM_039082095
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038938027   ⟸   XM_039082099
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038938028   ⟸   XM_039082100
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038938024   ⟸   XM_039082096
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038938026   ⟸   XM_039082098
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038938029   ⟸   XM_039082101
- Peptide Label: isoform X2

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:68433 AgrOrtholog
Ensembl Genes ENSRNOG00000061883 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000069377 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000087980 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1080.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7134715 IMAGE-MGC_LOAD
InterPro Aquaporin-like UniProtKB/Swiss-Prot
  Aquaporin_9 UniProtKB/Swiss-Prot
  MIP UniProtKB/Swiss-Prot
  MIP_CS UniProtKB/Swiss-Prot
KEGG Report rno:65054 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93419 IMAGE-MGC_LOAD
NCBI Gene 65054 ENTREZGENE
PANTHER PTHR43829:SF6 UniProtKB/Swiss-Prot
Pfam MIP UniProtKB/Swiss-Prot
PhenoGen Aqp9 PhenoGen
PRINTS AQUAPORIN9 UniProtKB/Swiss-Prot
  MINTRINSICP UniProtKB/Swiss-Prot
PROSITE MIP UniProtKB/Swiss-Prot
Superfamily-SCOP SSF81338 UniProtKB/Swiss-Prot
TIGR TC214842
TIGRFAMs MIP UniProtKB/Swiss-Prot
UniProt AQP9_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary O88815 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Aqp9  aquaporin 9      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization enriched in basolateral plasma membranes of hepatocytes 625402
gene_cellular_localization localized to the apical membrane 727570
gene_expression expressed in epididymal epithelium 727570