Gene: Adam10 (ADAM metallopeptidase domain 10) Rattus norvegicus
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Symbol: Adam10
Name: ADAM metallopeptidase domain 10
Description: ENCODES a protein that exhibits metalloendopeptidase activity; metallopeptidase activity; endopeptidase activity (ortholog); INVOLVED IN amyloid-beta formation; constitutive protein ectodomain proteolysis (ortholog); in utero embryonic development (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; interleukin-6 signaling pathway; Notch signaling pathway; ASSOCIATED WITH status epilepticus; thoracic aortic aneurysm; Alzheimer's disease 18 (ortholog); FOUND IN cell surface; dendritic spine; membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrolein
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: a disintegrin and metallopeptidase domain 10; a disintegrin and metalloprotease domain (ADAM) 10; a disintegrin and metalloprotease domain 10; ADAM 10; disintegrin and metalloproteinase domain-containing protein 10; kuzbanian; kuzbanian protein homolog; LOC501019; MADM; mammalian disintegrin-metalloprotease; RGD1566370; RGD1566370
Orthologs:
Homo sapiens (human) : ADAM10 (ADAM metallopeptidase domain 10)  HGNC  Alliance
Mus musculus (house mouse) : Adam10 (a disintegrin and metallopeptidase domain 10)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adam10 (ADAM metallopeptidase domain 10)
Pan paniscus (bonobo/pygmy chimpanzee) : ADAM10 (ADAM metallopeptidase domain 10)
Canis lupus familiaris (dog) : ADAM10 (ADAM metallopeptidase domain 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adam10 (ADAM metallopeptidase domain 10)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0877,107,355 - 77,237,483 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0875,842,118 - 75,974,564 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4875,200,657 - 75,289,572 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1875,307,687 - 75,310,191 (+)NCBI
Celera870,259,195 - 70,383,316 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Adam10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2032
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-07-10
Status: ACTIVE