Gene: Snx1 (sorting nexin 1) Rattus norvegicus
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Symbol: Snx1
Name: sorting nexin 1
Description: ENCODES a protein that exhibits epidermal growth factor receptor binding (ortholog); identical protein binding (ortholog); insulin receptor binding (ortholog); INVOLVED IN endosomal transport; positive regulation of protein catabolic process; early endosome to Golgi transport (ortholog); PARTICIPATES IN retromer-mediated pathway; ASSOCIATED WITH nemaline myopathy 6 (ortholog); FOUND IN cytosol; early endosome; membrane; INTERACTS WITH 2,4-dinitrotoluene; ammonium chloride; bisphenol A
AGR Description: Predicted to have phosphatidylinositol binding activity, protein dimerization activity, and signaling receptor binding activity; involved in endosomal transport and positive regulation of protein catabolic process; localizes to the cytosol and membrane; colocalizes with the early endosome; orthologous to human SNX1 (sorting nexin 1).
Merged Description: Predicted to have phosphatidylinositol binding activity, protein dimerization activity, and signaling receptor binding activity; involved in endosomal transport and positive regulation of protein catabolic process; localizes to the cytosol and membrane; colocalizes with the early endosome; orthologous to human SNX1 (sorting nexin 1); PARTICIPATES IN retromer-mediated pathway; INTERACTS WITH 2,4-dinitrotoluene; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC105373; sorting nexin-1
Orthologs:
Homo sapiens (human) : SNX1 (sorting nexin 1)  HGNC  Alliance
Mus musculus (house mouse) : Snx1 (sorting nexin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Snx1 (sorting nexin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SNX1 (sorting nexin 1)
Canis lupus familiaris (dog) : SNX1 (sorting nexin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Snx1 (sorting nexin 1)
Sus scrofa (pig) : SNX1 (sorting nexin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0871,745,687 - 71,786,182 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0871,414,974 - 71,455,127 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4870,370,336 - 70,408,991 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1870,389,389 - 70,428,045 (-)NCBI
Celera866,018,492 - 66,057,139 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Snx1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68935
Created: 2001-11-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.