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Gene: Tpbg (trophoblast glycoprotein) Rattus norvegicus

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Symbol:

Tpbg

Name:

trophoblast glycoprotein

RGD ID:

621453

Description:

Predicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to act upstream of or within several processes, including dendrite arborization; olfactory learning; and positive regulation of intracellular signal transduction. Predicted to be located in axon terminus; dendrite; and endoplasmic reticulum. Predicted to be active in plasma membrane. Orthologous to human TPBG (trophoblast glycoprotein); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

5T4; 5T4 oncofetal trophoblast glycoprotein; 5T4 oncotrophoblast glycoprotein; MGC93332; WAIF1; wnt-activated inhibitory factor 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TPBG (trophoblast glycoprotein)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Tpbg (trophoblast glycoprotein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tpbg (trophoblast glycoprotein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TPBG (trophoblast glycoprotein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TPBG (trophoblast glycoprotein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tpbg (trophoblast glycoprotein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TPBG (trophoblast glycoprotein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TPBG (trophoblast glycoprotein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tpbg (trophoblast glycoprotein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	TPBG (trophoblast glycoprotein)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Tpbg (trophoblast glycoprotein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tpbgb (trophoblast glycoprotein b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tpbgl (trophoblast glycoprotein-like)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	tpbga (trophoblast glycoprotein a)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Caenorhabditis elegans (roundworm):	lron-3	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	lron-3	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG6959	Alliance	DIOPT (Hieranoid\|OMA\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG6959	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	tpbg	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	tpbg	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	95,673,993 - 95,677,364 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	95,629,267 - 95,678,394 (+)	Ensembl				GRCr8
mRatBN7.2	8	86,793,953 - 86,797,324 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	86,793,749 - 86,797,741 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	92,462,281 - 92,465,651 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	90,661,732 - 90,665,103 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	88,505,828 - 88,509,196 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	93,491,761 - 93,495,132 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	93,491,761 - 93,495,130 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	93,006,542 - 93,009,913 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	91,075,960 - 91,079,329 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	86,406,590 - 86,409,959 (+)	NCBI		Celera
RGSC_v3.1	8	91,095,414 - 91,098,784 (+)	NCBI
Cytogenetic Map	8	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

immunodeficiency 23 (ISO)

Prostatic Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2-palmitoylglycerol (ISO)

4,4'-diaminodiphenylmethane (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (ISO)

afimoxifene (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (EXP,ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

bisphenol AF (ISO)

cadmium dichloride (EXP,ISO)

calcitriol (ISO)

chlorpyrifos (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) chloride (ISO)

copper(II) sulfate (ISO)

corticosterone (EXP)

cyclosporin A (ISO)

cylindrospermopsin (ISO)

DDE (ISO)

dibutyl phthalate (EXP)

diuron (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

epoxiconazole (ISO)

flavonoids (EXP)

flutamide (EXP)

folic acid (ISO)

FR900359 (ISO)

furan (EXP)

gentamycin (EXP)

ivermectin (ISO)

mercury dibromide (ISO)

methylmercury chloride (ISO)

nickel sulfate (ISO)

okadaic acid (ISO)

ozone (ISO)

p-chloromercuribenzoic acid (ISO)

panobinostat (ISO)

paracetamol (EXP,ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP,ISO)

phenylmercury acetate (ISO)

potassium dichromate (ISO)

progesterone (EXP,ISO)

quercetin (ISO)

SB 431542 (ISO)

serpentine asbestos (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

succimer (ISO)

temozolomide (ISO)

testosterone (ISO)

thiram (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

triptonide (ISO)

troglitazone (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell chemotaxis (ISO)

dendrite arborization (ISO)

mesenchymal cell migration (ISO)

negative regulation of canonical Wnt signaling pathway (IBA)

negative regulation of cell population proliferation (ISO)

olfactory learning (ISO)

positive regulation of chemotaxis (ISO)

positive regulation of ERK1 and ERK2 cascade (ISO)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ISO)

positive regulation of synapse assembly (ISO)

protein localization to plasma membrane (ISO)

synaptic transmission, GABAergic (ISO)

Cellular Component

axon terminus (ISO)

cytoplasm (ISO)

dendrite (ISO)

endoplasmic reticulum (ISO)

membrane (IEA)

plasma membrane (IBA,IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Glycosylation and epitope mapping of the 5T4 glycoprotein oncofoetal antigen.	Shaw DM, etal., Biochem J 2002 Apr 1;363(Pt 1):137-45.

Additional References at PubMed

PMID:12477932	PMID:15489334	PMID:15977177	PMID:19581412	PMID:24613359

Genomics

Comparative Map Data

Tpbg
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	95,673,993 - 95,677,364 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	95,629,267 - 95,678,394 (+)	Ensembl				GRCr8
mRatBN7.2	8	86,793,953 - 86,797,324 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	86,793,749 - 86,797,741 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	92,462,281 - 92,465,651 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	90,661,732 - 90,665,103 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	88,505,828 - 88,509,196 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	93,491,761 - 93,495,132 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	93,491,761 - 93,495,130 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	93,006,542 - 93,009,913 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	91,075,960 - 91,079,329 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	86,406,590 - 86,409,959 (+)	NCBI		Celera
RGSC_v3.1	8	91,095,414 - 91,098,784 (+)	NCBI
Cytogenetic Map	8	q31	NCBI

TPBG
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	82,362,983 - 82,367,420 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	82,363,206 - 82,367,420 (+)	Ensembl			hg38	GRCh38
GRCh37	6	83,072,700 - 83,077,137 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	83,130,258 - 83,133,347 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	6	83,130,257 - 83,133,333	NCBI
Celera	6	83,506,010 - 83,510,221 (+)	NCBI		Celera
Cytogenetic Map	6	q14.1	NCBI
HuRef	6	80,300,641 - 80,304,852 (+)	NCBI		HuRef
CHM1_1	6	83,170,653 - 83,174,864 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	83,582,429 - 83,586,866 (+)	NCBI		T2T-CHM13v2.0

Tpbg
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	85,724,433 - 85,729,110 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	85,724,433 - 85,729,093 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	85,842,380 - 85,847,057 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	85,842,380 - 85,847,040 (+)	Ensembl			mm10	GRCm38
MGSCv37	9	85,735,987 - 85,740,662 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	85,639,128 - 85,642,507 (+)	NCBI		MGSCv36	mm8
Celera	9	82,936,659 - 82,941,333 (+)	NCBI		Celera
Cytogenetic Map	9	E3.1	NCBI
cM Map	9	46.4	NCBI

Tpbg
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955411	10,203,144 - 10,206,711 (+)	NCBI	ChiLan1.0	ChiLan1.0

TPBG
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	102,464,594 - 102,473,670 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	100,349,222 - 100,353,825 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	80,265,172 - 80,273,022 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	83,530,184 - 83,536,290 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	83,530,571 - 83,531,915 (+)	Ensembl			panPan2	panpan1.1

TPBG
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	42,872,289 - 42,878,071 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	42,871,239 - 42,875,151 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	42,750,516 - 42,753,814 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	43,640,373 - 43,643,675 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
UMICH_Zoey_3.1	12	42,958,895 - 42,962,193 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	42,928,419 - 42,931,719 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	43,083,154 - 43,086,460 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Tpbg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	78,192,165 - 78,195,794 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936510	8,275,660 - 8,278,367 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936510	8,274,760 - 8,278,955 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TPBG
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	83,847,819 - 83,850,881 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	83,847,809 - 83,851,326 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	94,386,257 - 94,388,336 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TPBG
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	7,047,658 - 7,051,390 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	7,049,415 - 7,050,680 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666040	183,264,600 - 183,268,868 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tpbg
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624799	12,226,350 - 12,230,701 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624799	12,226,350 - 12,325,178 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Tpbg
8 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	474
Count of miRNA genes:	240
Interacting mature miRNAs:	283
Transcripts:	ENSRNOT00000014326
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300177	Cm2	Cardiac mass QTL 2	3.65		heart mass (VT:0007028)	heart weight (CMO:0000017)	8	63141536	109261840	Rat
1549909	Stresp11	Stress response QTL 11	6.83	0.0019	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	8	82352698	127352698	Rat
12879878	Bw183	Body weight QTL 183		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	8	62848139	107848139	Rat
1549908	Neudeg1	Neurodegradation QTL 1	5.5	0	nervous system integrity trait (VT:0010566)	logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)	8	58337123	103337123	Rat
12879879	Cm99	Cardiac mass QTL 99		0.001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	62848139	107848139	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	49849908	118871671	Rat
9590292	Uminl3	Urine mineral level QTL 3	3.62	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	8	80768445	125768445	Rat
1331804	Cm30	Cardiac mass QTL 30	3.77443		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	8	62970527	107970527	Rat
1578769	Uae31	Urinary albumin excretion QTL 31	3.3	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	39106363	103375781	Rat
1298079	Activ2	Activity QTL 2	9.5	0.000001	voluntary movement trait (VT:0003491)	rearing measurement (CMO:0001515)	8	50763951	95763951	Rat
12879880	Cm100	Cardiac mass QTL 100		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	8	62848139	107848139	Rat
12879881	Cm101	Cardiac mass QTL 101		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	8	62848139	107848139	Rat
12879882	Am8	Aortic mass QTL 8		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	8	62848139	107848139	Rat
12879883	Kidm65	Kidney mass QTL 65		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	62848139	107848139	Rat
70161	Bp62	Blood pressure QTL 62	2.9	0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	51589699	99045312	Rat
71120	Niddm21	Non-insulin dependent diabetes mellitus QTL 21	3.73		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	8	66992095	111992095	Rat
1358912	Bw51	Body weight QTL 51	2.95		body mass (VT:0001259)	body weight (CMO:0000012)	8	60248093	105248093	Rat
634332	Pia18	Pristane induced arthritis QTL 18	4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	84192326	132782436	Rat
1578765	Klgr1	Kidney lesion grade QTL 1	3.3	0.0001	kidney morphology trait (VT:0002135)	organ lesion measurement (CMO:0000677)	8	39106363	103375781	Rat
1300171	Bp184	Blood pressure QTL 184	3.66		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	8	79394435	132782436	Rat
1578755	Pur5	Proteinuria QTL 5	3.3	0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	8	39106258	103375958	Rat
631210	Bw3	Body weight QTL3	5.9		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	8	61019838	121662124	Rat
2293697	Bmd39	Bone mineral density QTL 39			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	8	62848139	107848139	Rat
8662823	Vetf5	Vascular elastic tissue fragility QTL 5	1.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	8	63404444	108404444	Rat
1358896	Bp262	Blood pressure QTL 262	2.89		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	35464071	107982864	Rat
1331837	Bw23	Body weight QTL 23	4.19	0.00007	body mass (VT:0001259)	body weight (CMO:0000012)	8	55428416	107963099	Rat
1331838	Niddm61	Non-insulin dependent diabetes mellitus QTL 61	3.53	0.0004	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	8	62963099	107963099	Rat
8694446	Bw170	Body weight QTL 170	12.07	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	8	80768445	125768445	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	70041301	121080908	Rat
1331769	Rf39	Renal function QTL 39	3.871		urine output (VT:0003620)	timed urine volume (CMO:0000260)	8	50763951	107970527	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	68690349	119799881	Rat
10450865	Bw175	Body weight QTL 175	4.1		total fat pad mass (VT:0015008)	adipose tissue molecular composition measurement (CMO:0000484)	8	84192326	129192326	Rat
1358907	Cm40	Cardiac mass QTL 40	1.89		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	35464071	107982864	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	55428333	127966348	Rat
2316950	Scl66	Serum cholesterol level QTL 66	4.1		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	39106363	114525825	Rat
2300181	Bmd55	Bone mineral density QTL 55	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	85348065	130348065	Rat
724540	Uae8	Urinary albumin excretion QTL 8	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	8	39106258	103375958	Rat
10402857	Bp380	Blood pressure QTL 380		0.95	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	62848139	107848139	Rat
1358892	Kidm26	Kidney mass QTL 26	3.69		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	35464071	107982864	Rat
631664	Hcar3	Hepatocarcinoma resistance QTL 3	2.9	0.0005	liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	8	62982864	107982864	Rat
2301402	Bp316	Blood pressure QTL 316		0.005	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	62848139	107848139	Rat
8694200	Abfw4	Abdominal fat weight QTL 4	9.07	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	8	80768445	125768445	Rat
8694392	Bw161	Body weight QTL 161	8.06	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	8	80768445	125768445	Rat
61437	Cia6	Collagen induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	91340911	131690273	Rat

Markers in Region

RH133240

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	86,796,926 - 86,797,106 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	93,494,735 - 93,494,914	NCBI	Rnor6.0
Rnor_5.0	8	93,009,516 - 93,009,695	UniSTS	Rnor5.0
RGSC_v3.4	8	91,078,934 - 91,079,113	UniSTS	RGSC3.4
Celera	8	86,409,564 - 86,409,743	UniSTS
RH 3.4 Map	8	997.7	UniSTS
Cytogenetic Map	8	q31	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	154	91	90	59	82	59	6	346	182	11	133	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001431631	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_031807	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006243499	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008766457	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595935	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF063939	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC087011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000014326 ⟹ ENSRNOP00000014326

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	95,629,267 - 95,677,747 (+)	Ensembl
mRatBN7.2 Ensembl	8	86,794,685 - 86,797,741 (+)	Ensembl
Rnor_6.0 Ensembl	8	93,491,761 - 93,495,130 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000089491 ⟹ ENSRNOP00000075124

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	95,629,275 - 95,677,747 (+)	Ensembl
mRatBN7.2 Ensembl	8	86,793,759 - 86,797,741 (+)	Ensembl
Rnor_6.0 Ensembl	8	93,492,122 - 93,495,125 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104677 ⟹ ENSRNOP00000085521

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	95,629,267 - 95,677,747 (+)	Ensembl
mRatBN7.2 Ensembl	8	86,793,749 - 86,797,741 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000130631 ⟹ ENSRNOP00000101915

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	95,673,535 - 95,678,394 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000139740 ⟹ ENSRNOP00000100654

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	95,673,788 - 95,678,394 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000153056 ⟹ ENSRNOP00000099969

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	95,673,390 - 95,678,117 (+)	Ensembl

RefSeq Acc Id:

NM_031807 ⟹ NP_113995

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	95,673,993 - 95,677,362 (+)	NCBI
mRatBN7.2	8	86,793,953 - 86,797,322 (+)	NCBI
Rnor_6.0	8	93,491,761 - 93,495,130 (+)	NCBI
Rnor_5.0	8	93,006,542 - 93,009,913 (+)	NCBI
RGSC_v3.4	8	91,075,960 - 91,079,329 (+)	RGD
Celera	8	86,406,590 - 86,409,959 (+)	RGD

Sequence:

show sequence

CAAGAGATCCACCAGCGGTTTTGTTTCTGTCCGAGGTCGCCCATCCGATCCTTCCCTGAGAGAG
GCGCCAACAAAGGAGTTGAGGAGGTGCCACCCACCCCAGCGGCGGCTGGAGGAGGAGCGCCAAG
GCCCGTGTCCCGACCCGCCGTGCGTACTCACTGGAGGGAAGGGCGGGGTACCGTTCCGGGAGGG
AGACGCCCGGTGGCCCGGGGTTAGCCAAGTTCCAGCTTTGGCGTCCCTTCCTTGGCTCCCACGC
GAGGAAAGTTTGCCGTCGACGCTTGCGGCCGCCTCGCGCCCGCCGGGCCCAGGCGGTCGAGTCT
TCGGAGCGGGCACCGTCCCAGCTCCGGGGAACCGCGAGCCGCGATGCCTGGGGCGGGCTCCCGG
GGCCCCTCTGCCGGGGACGGACGGCTGCGGTTGGCAAGGCTGGCGCTAGTGCTGCTGGGTTGGG
TCTCCGCGTCGGCCCCCAGCTCTTCGCTACCCTCGTCTTCCACCTCCCCGGCTGCCTTCCTGGC
TTCGGGGTCTGCGCAGCCTCCGCCGGCCGAGCGATGCCCCGCTGCGTGCGAGTGCTCCGAGGCG
GCGCGCACGGTTAAGTGCGTGAACCGCAACCTGCTGGAGGTGCCTGCGGACCTGCCACCTTACG
TGCGCAACCTTTTCCTCACTGGCAACCAGATGACCGTGCTCCCGGCTGGCGCCTTCGCCCGCCA
GCCGCCGCTCGCCGACCTGGCAGTGCTCAACCTCAGCGGCAACCACCTGAAGGAGGTGGGTGCA
GGTGCCTTCGAGCATCTGCCCGGCCTTCGCCGGCTTGACCTCAGCCACAATCCTCTCACCAACC
TCAGCGCCTTCACCTTCGCGGGCAGCAACGTCAGCGTCTCGACCCCCAGCCCCCTATTGGAGCT
GATCTTGAATCACATCGTGCCCCCTGAGGATCAGCGGCAGAATGGGAGCTTCGAGGGCATGGTG
GCCTTCGAGGGCATGGTGGCAGCTGCCCTGCGCTCAGGCCTTGCACTCCGAGGGCTGCATCACC
TAGAGCTGGCCAGCAATCACTTTCTTTACCTGCCTCGGGACTTATTGGACCAACTGCCAAGTCT
CAAGCACCTGGACCTCAGGAACAACTCCCTGGTGAGCCTGACCTATGCATCTTTCCGCAACCTG
ACACACCTCGAAAGCCTCCACTTGGAGGACAATGCCCTCAAGGTCCTTCACAACTCCACCTTGG
CTGAGTGGCAAGGCCTGGCTCATGTCAGGGTGTTCCTGGACAACAATCCCTGGGTTTGTGACTG
CTACATGGCTGACATGGTGTCTTGGCTTAAAGAGACAGAGGTGGTGCCGGATAAAGCCAGGCTC
ACCTGCGCATTCCCAGAAAAAATGAGGAACCGTGGCCTCTTGGACCTCACCAGCTCTGACCTGG
ACTGTGACGCTACCCTTCCCCAATCCCTGCAGACTTCCTATGTCTTCTTAGGTATTGTTTTAGC
TCTGATAGGCGCTATTTTCCTCCTCGTTTTGTATTTGAACCGGAAAGGCATAAAAAAGTGGATG
CATAACATCAGAGATGCCTGCAGGGATCACATGGAAGGGTATCATTACAGATACGAAATCAATG
CGGACCCCAGCTTAACAAATCTCAGTTCCAACTCGGATGTCTGAGAACTAGGACTGGCCAAGGA
GGCTCTGCATGAGGTGTATGTAGACCTTAAGGTCCCTCCCCCCCCTTTACTATGCTTGCTCCAC
TTCCACCCTCCACCGTAGACACCATTGATTTTGATCCTCGTTATGTAAAATTCTTGGTGTGTTC
TGTTAATGTAAGGACATGAACAACTGTGCATATAATGTTTATTTACCCCTTTCCTTTTGGTACT
CCTCGATGCCTGCAGAGGGACTTTTTTTTTTCCTCTCAAGTTGCAGCATGGACATGGACTCTTA
GTTGAGCTCAAGGCGTAGCACAGATAACATTCAACGGGAGCTGCCTCAATTTCTTTTTTCTTTT
TTGAGAAAAGTACTTTATTCATAAATATGAGTTTTATTGTCACCTACCTAAATTATGGAGGAAA
TATTGCATCCCCAAATTGCCTGCAGACCTTAGCAAGCTCTTACCTAGAACTTGGTAGTGCACAG
GAGCACCTGCATCCGAGAGCATGCGTACATTTTACTGTTCTGCATATTAAAAAAATTGCAACGT
CAGATAACTTCTTTGACAGACTAAATTACTTTTTTGATTGCAGTTTACATGAAACTGACCCGAG
GTTTTTCTTTTTCTTTTTTTATAAACTGCATTGAGACCCAACAGACTGGATTGTTATATAAAAA
AAGAAAAATCAATAAAAGAGTCTCAAAAG

hide sequence

RefSeq Acc Id:

XM_006243499 ⟹ XP_006243561

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	95,674,036 - 95,677,364 (+)	NCBI
mRatBN7.2	8	86,794,188 - 86,797,324 (+)	NCBI
Rnor_6.0	8	93,491,984 - 93,495,132 (+)	NCBI
Rnor_5.0	8	93,006,542 - 93,009,913 (+)	NCBI

Sequence:

show sequence

CGATCTCTCCCGCAGCCTCGGCCCTCCCCCGCCCCCCGGCTTGGTTTTTCCCGGTCGTGGAGGT
TGGGCCAGGGGCTGGGGTGAGAGGAGAGTCGGCGCCCGCAGCAGGAGCCGGGAAGGCGCGTGGA
CTGGGGTGGCCCTCGGAGTTGGCTTTGGAAGCGCGGGGCGCGGAGGTCGCCCATCCGATCCTTC
CCTGAGAGAGGCGCCAACAAAGGAGTTGAGGAGGTGCCACCCACCCCAGCGGCGGCTGGAGGAG
GAGCGCCAAGGCCCGTGTCCCGACCCGCCGTGCGTACTCACTGGAGGGAAGGGCGGGGTACCGC
TCCGGGAGGGAGACGCCCGGTGGCCCGGGGTTAGCCAAGTTCCAGCTTTGGCGTCCCTTCCTTG
GCTCCCACGCGAGGAAAGTTTGCCGTCGACGCTTGCGGCCGTCTCGCGCCCGCCGGGCCCAGGC
GGTCGAGTCTTCGGAGCGGGCACCGTCCCAGCTCCGGGGAACCGCGAGCCGCGATGCCTGGGGC
GGGCTCCCGGGGCCCCTCTGCCGGGGACGGACGGCTGCGGTTGGCAAGGCTGGCGCTAGTGCTG
CTGGGTTGGGTCTCCGCGTCGGCCCCCAGCTCTTCGCTACCCTCGTCTTCCACCTCCCCGGCTG
CCTTCCTGGCTTCGGGGTCTGCGCAGCCTCCGCCGGCCGAGCGATGCCCCGCTGCGTGCGAGTG
CTCCGAGGCGGCGCGCACGGTTAAGTGCGTGAACCGCAACCTGCTGGAGGTGCCTGCGGACCTG
CCACCTTACGTGCGCAACCTTTTCCTCACTGGCAACCAGATGACCGTGCTCCCGGCTGGCGCCT
TCGCCCGCCAGCCGCCGCTCGCCGACCTGGCAGTGCTCAACCTCAGCGGCAACCACCTGAAGGA
GGTGGGTGCAGGTGCCTTCGAGCATCTGCCCGGCCTTCGCCGGCTTGACCTCAGCCACAATCCT
CTCACCAACCTCAGCGCCTTCACCTTCGCGGGCAGCAACGTCAGCGTCTCGACCCCCAGCCCCC
TGTTGGAGCTGATCTTGAATCACATCGTGCCCCCTGAGGATCAGCGGCAGAATGGGAGCTTCGA
GGGCATGGTGGCCTTCGAGGGCATGGTGGCAGCTGCCCTGCGCTCAGGCCTTGCACTCCGAGGG
CTGCATCACCTAGAGCTGGCCAGCAATCACTTTCTTTACCTGCCTCGGGACTTATTGGACCAAC
TGCCAAGTCTCAAGCACCTGGACCTCAGGAACAACTCCCTGGTGAGCCTGACCTATGCATCTTT
CCGCAACCTGACACACCTCGAAAGCCTCCACTTGGAGGACAATGCCCTCAAGGTCCTTCACAAC
TCCACCTTGGCTGAGTGGCAAGGCCTGGCTCATGTCAGGGTGTTCCTGGACAACAATCCCTGGG
TTTGTGACTGCTACATGGCTGACATGGTGTCTTGGCTTAAAGAGACAGAGGTGGTGCCGGATAA
AGCCAGGCTCACCTGCGCATTCCCAGAAAAAATGAGGAACCGTGGCCTCTTGGACCTCACCAGC
TCTGACCTGGACTGTGACGCTACCCTTCCCCAATCCCTGCAGACTTCCTATGTCTTCTTAGGTA
TTGTTTTAGCTCTGATAGGCGCTATTTTCCTCCTCGTTTTGTATTTGAACCGGAAAGGCATAAA
GAAGTGGATGCATAACATCAGAGATGCCTGCAGGGATCACATGGAAGGGTATCATTACAGATAC
GAAATCAATGCGGACCCCAGATTAACAAATCTCAGTTCCAACTCGGATGTCTGAGAACTAGGAC
TGGCCAAGGAGGACTCTGCATGAGGTGTATGTAGACTTAAGGTCCCTCCCCCCCCTTTACTATG
CTTGCTCCACTTCCACCCTCCACCGTAGACACCATTGATTTTGATCCTCGTTATGTAAAATTCT
TGGTGTGTTCTGTTAATGTAAGGACATGAACAACTGTGCATATAATGTTTATTTACCCCTTTCC
TTTTGGTACTCCTCGATGCCTGCAGAGGGACTTTTTTTTTTCCTCTCAAGTTGCAGCATGGACA
TGGACTCTTAGTTGAGCTCAAGGCGTAGCACAGATAACATTCAACGGGAGCTGCCTCAATTTCT
TTTTTCTTTTTTGAGAAAAGTACTTTATTCATAAATATGAGTTTTATTGTCACCTACCTAAATT
ATGGAGGAAATATTGCATCCCCAAATTGCCTGCAGACCTTAGCAAGCTCTTACCTAGAACTTGG
TAGTGCACAGGAGCACCTGCATCCGAGAGCATGCGTACATTTTACTGTTCTGCATATTAAAAAA
ATTGCAACGTCAGATAACTTCTTTGACAGACTAAATTACTTTTTTGATTGCAGTTTACATGAAA
CTGACCCGAGGTTTTTCTTTTTCTTTTTTTATAAACTGCATTGAGACCCAACAGACTGGATTGT
TATATAAAAAAAGAAAAATCAATAAAAGAGTCTCAAAAGAA

hide sequence

RefSeq Acc Id:

XM_008766457 ⟹ XP_008764679

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	95,674,742 - 95,677,364 (+)	NCBI
mRatBN7.2	8	86,794,684 - 86,797,324 (+)	NCBI
Rnor_6.0	8	93,492,511 - 93,495,132 (+)	NCBI

Sequence:

show sequence

GGTGGTCGGCGGGGGCGGTGGGAGCTGGGATCCGGAAAAGGGAGAAGTTTTCTCGCTGGACTCC
GCGGGGTCTGCGTGAAGTTCGAGGCGGGAGAAGGGCAATCCGGCTAGAAGCCAGGCGGGAGGTG
GCCCGGGTCGCCCATCCGATCCTTCCCTGAGAGAGGCGCCAACAAAGGAGTTGAGGAGGTGCCA
CCCACCCCAGCGGCGGCTGGAGGAGGAGCGCCAAGGCCCGTGTCCCGACCCGCCGTGCGTACTC
ACTGGAGGGAAGGGCGGGGTACCGCTCCGGGAGGGAGACGCCCGGTGGCCCGGGGTTAGCCAAG
TTCCAGCTTTGGCGTCCCTTCCTTGGCTCCCACGCGAGGAAAGTTTGCCGTCGACGCTTGCGGC
CGTCTCGCGCCCGCCGGGCCCAGGCGGTCGAGTCTTCGGAGCGGGCACCGTCCCAGCTCCGGGG
AACCGCGAGCCGCGATGCCTGGGGCGGGCTCCCGGGGCCCCTCTGCCGGGGACGGACGGCTGCG
GTTGGCAAGGCTGGCGCTAGTGCTGCTGGGTTGGGTCTCCGCGTCGGCCCCCAGCTCTTCGCTA
CCCTCGTCTTCCACCTCCCCGGCTGCCTTCCTGGCTTCGGGGTCTGCGCAGCCTCCGCCGGCCG
AGCGATGCCCCGCTGCGTGCGAGTGCTCCGAGGCGGCGCGCACGGTTAAGTGCGTGAACCGCAA
CCTGCTGGAGGTGCCTGCGGACCTGCCACCTTACGTGCGCAACCTTTTCCTCACTGGCAACCAG
ATGACCGTGCTCCCGGCTGGCGCCTTCGCCCGCCAGCCGCCGCTCGCCGACCTGGCAGTGCTCA
ACCTCAGCGGCAACCACCTGAAGGAGGTGGGTGCAGGTGCCTTCGAGCATCTGCCCGGCCTTCG
CCGGCTTGACCTCAGCCACAATCCTCTCACCAACCTCAGCGCCTTCACCTTCGCGGGCAGCAAC
GTCAGCGTCTCGACCCCCAGCCCCCTGTTGGAGCTGATCTTGAATCACATCGTGCCCCCTGAGG
ATCAGCGGCAGAATGGGAGCTTCGAGGGCATGGTGGCCTTCGAGGGCATGGTGGCAGCTGCCCT
GCGCTCAGGCCTTGCACTCCGAGGGCTGCATCACCTAGAGCTGGCCAGCAATCACTTTCTTTAC
CTGCCTCGGGACTTATTGGACCAACTGCCAAGTCTCAAGCACCTGGACCTCAGGAACAACTCCC
TGGTGAGCCTGACCTATGCATCTTTCCGCAACCTGACACACCTCGAAAGCCTCCACTTGGAGGA
CAATGCCCTCAAGGTCCTTCACAACTCCACCTTGGCTGAGTGGCAAGGCCTGGCTCATGTCAGG
GTGTTCCTGGACAACAATCCCTGGGTTTGTGACTGCTACATGGCTGACATGGTGTCTTGGCTTA
AAGAGACAGAGGTGGTGCCGGATAAAGCCAGGCTCACCTGCGCATTCCCAGAAAAAATGAGGAA
CCGTGGCCTCTTGGACCTCACCAGCTCTGACCTGGACTGTGACGCTACCCTTCCCCAATCCCTG
CAGACTTCCTATGTCTTCTTAGGTATTGTTTTAGCTCTGATAGGCGCTATTTTCCTCCTCGTTT
TGTATTTGAACCGGAAAGGCATAAAGAAGTGGATGCATAACATCAGAGATGCCTGCAGGGATCA
CATGGAAGGGTATCATTACAGATACGAAATCAATGCGGACCCCAGATTAACAAATCTCAGTTCC
AACTCGGATGTCTGAGAACTAGGACTGGCCAAGGAGGACTCTGCATGAGGTGTATGTAGACTTA
AGGTCCCTCCCCCCCCTTTACTATGCTTGCTCCACTTCCACCCTCCACCGTAGACACCATTGAT
TTTGATCCTCGTTATGTAAAATTCTTGGTGTGTTCTGTTAATGTAAGGACATGAACAACTGTGC
ATATAATGTTTATTTACCCCTTTCCTTTTGGTACTCCTCGATGCCTGCAGAGGGACTTTTTTTT
TTCCTCTCAAGTTGCAGCATGGACATGGACTCTTAGTTGAGCTCAAGGCGTAGCACAGATAACA
TTCAACGGGAGCTGCCTCAATTTCTTTTTTCTTTTTTGAGAAAAGTACTTTATTCATAAATATG
AGTTTTATTGTCACCTACCTAAATTATGGAGGAAATATTGCATCCCCAAATTGCCTGCAGACCT
TAGCAAGCTCTTACCTAGAACTTGGTAGTGCACAGGAGCACCTGCATCCGAGAGCATGCGTACA
TTTTACTGTTCTGCATATTAAAAAAATTGCAACGTCAGATAACTTCTTTGACAGACTAAATTAC
TTTTTTGATTGCAGTTTACATGAAACTGACCCGAGGTTTTTCTTTTTCTTTTTTTATAAACTGC
ATTGAGACCCAACAGACTGGATTGTTATATAAAAAAAGAAAAATCAATAAAAGAGTCTCAAAAG
AA

hide sequence

RefSeq Acc Id:

XM_017595935 ⟹ XP_017451424

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	95,674,363 - 95,677,364 (+)	NCBI
mRatBN7.2	8	86,794,476 - 86,797,324 (+)	NCBI
Rnor_6.0	8	93,492,177 - 93,495,132 (+)	NCBI

Sequence:

show sequence

GCCAGGTTTGGAGCCTGGAGGCGGGACCCGGGCTCCGTTCTATACCAGGGCGTGATGAGAGCGG
GGGTCCTGGCTGCTACCCCGCCCACGGTCCCACGGCCGCTTCGTTGGCGGGTTCCCTCCGCTCT
TCTGGAGGCGCCTGGACCCTCTCGGGGTCGGGGAGCTGGAGGCCCACGAGTCGAGAGTGGGCGA
CAGCTCTAGGGCTCTGCTCTCCTTTCCCCACTAATCCAAGGAGGTCGCCCATCCGATCCTTCCC
TGAGAGAGGCGCCAACAAAGGAGTTGAGGAGGTGCCACCCACCCCAGCGGCGGCTGGAGGAGGA
GCGCCAAGGCCCGTGTCCCGACCCGCCGTGCGTACTCACTGGAGGGAAGGGCGGGGTACCGCTC
CGGGAGGGAGACGCCCGGTGGCCCGGGGTTAGCCAAGTTCCAGCTTTGGCGTCCCTTCCTTGGC
TCCCACGCGAGGAAAGTTTGCCGTCGACGCTTGCGGCCGTCTCGCGCCCGCCGGGCCCAGGCGG
TCGAGTCTTCGGAGCGGGCACCGTCCCAGCTCCGGGGAACCGCGAGCCGCGATGCCTGGGGCGG
GCTCCCGGGGCCCCTCTGCCGGGGACGGACGGCTGCGGTTGGCAAGGCTGGCGCTAGTGCTGCT
GGGTTGGGTCTCCGCGTCGGCCCCCAGCTCTTCGCTACCCTCGTCTTCCACCTCCCCGGCTGCC
TTCCTGGCTTCGGGGTCTGCGCAGCCTCCGCCGGCCGAGCGATGCCCCGCTGCGTGCGAGTGCT
CCGAGGCGGCGCGCACGGTTAAGTGCGTGAACCGCAACCTGCTGGAGGTGCCTGCGGACCTGCC
ACCTTACGTGCGCAACCTTTTCCTCACTGGCAACCAGATGACCGTGCTCCCGGCTGGCGCCTTC
GCCCGCCAGCCGCCGCTCGCCGACCTGGCAGTGCTCAACCTCAGCGGCAACCACCTGAAGGAGG
TGGGTGCAGGTGCCTTCGAGCATCTGCCCGGCCTTCGCCGGCTTGACCTCAGCCACAATCCTCT
CACCAACCTCAGCGCCTTCACCTTCGCGGGCAGCAACGTCAGCGTCTCGACCCCCAGCCCCCTG
TTGGAGCTGATCTTGAATCACATCGTGCCCCCTGAGGATCAGCGGCAGAATGGGAGCTTCGAGG
GCATGGTGGCCTTCGAGGGCATGGTGGCAGCTGCCCTGCGCTCAGGCCTTGCACTCCGAGGGCT
GCATCACCTAGAGCTGGCCAGCAATCACTTTCTTTACCTGCCTCGGGACTTATTGGACCAACTG
CCAAGTCTCAAGCACCTGGACCTCAGGAACAACTCCCTGGTGAGCCTGACCTATGCATCTTTCC
GCAACCTGACACACCTCGAAAGCCTCCACTTGGAGGACAATGCCCTCAAGGTCCTTCACAACTC
CACCTTGGCTGAGTGGCAAGGCCTGGCTCATGTCAGGGTGTTCCTGGACAACAATCCCTGGGTT
TGTGACTGCTACATGGCTGACATGGTGTCTTGGCTTAAAGAGACAGAGGTGGTGCCGGATAAAG
CCAGGCTCACCTGCGCATTCCCAGAAAAAATGAGGAACCGTGGCCTCTTGGACCTCACCAGCTC
TGACCTGGACTGTGACGCTACCCTTCCCCAATCCCTGCAGACTTCCTATGTCTTCTTAGGTATT
GTTTTAGCTCTGATAGGCGCTATTTTCCTCCTCGTTTTGTATTTGAACCGGAAAGGCATAAAGA
AGTGGATGCATAACATCAGAGATGCCTGCAGGGATCACATGGAAGGGTATCATTACAGATACGA
AATCAATGCGGACCCCAGATTAACAAATCTCAGTTCCAACTCGGATGTCTGAGAACTAGGACTG
GCCAAGGAGGACTCTGCATGAGGTGTATGTAGACTTAAGGTCCCTCCCCCCCCTTTACTATGCT
TGCTCCACTTCCACCCTCCACCGTAGACACCATTGATTTTGATCCTCGTTATGTAAAATTCTTG
GTGTGTTCTGTTAATGTAAGGACATGAACAACTGTGCATATAATGTTTATTTACCCCTTTCCTT
TTGGTACTCCTCGATGCCTGCAGAGGGACTTTTTTTTTTCCTCTCAAGTTGCAGCATGGACATG
GACTCTTAGTTGAGCTCAAGGCGTAGCACAGATAACATTCAACGGGAGCTGCCTCAATTTCTTT
TTTCTTTTTTGAGAAAAGTACTTTATTCATAAATATGAGTTTTATTGTCACCTACCTAAATTAT
GGAGGAAATATTGCATCCCCAAATTGCCTGCAGACCTTAGCAAGCTCTTACCTAGAACTTGGTA
GTGCACAGGAGCACCTGCATCCGAGAGCATGCGTACATTTTACTGTTCTGCATATTAAAAAAAT
TGCAACGTCAGATAACTTCTTTGACAGACTAAATTACTTTTTTGATTGCAGTTTACATGAAACT
GACCCGAGGTTTTTCTTTTTCTTTTTTTATAAACTGCATTGAGACCCAACAGACTGGATTGTTA
TATAAAAAAAGAAAAATCAATAAAAGAGTCTCAAAAGAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001418560	(Get FASTA)	NCBI Sequence Viewer
	NP_113995	(Get FASTA)	NCBI Sequence Viewer
	XP_006243561	(Get FASTA)	NCBI Sequence Viewer
	XP_008764679	(Get FASTA)	NCBI Sequence Viewer
	XP_017451424	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAF21770	(Get FASTA)	NCBI Sequence Viewer
	AAH87011	(Get FASTA)	NCBI Sequence Viewer
	EDL77640	(Get FASTA)	NCBI Sequence Viewer
	EDL77641	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000014326.1
	ENSRNOP00000075124.1
	ENSRNOP00000085521.1
	ENSRNOP00000099969
	ENSRNOP00000100654
	ENSRNOP00000101915
GenBank Protein	Q5PQV5	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_113995 ⟸ NM_031807
- Peptide Label:	precursor
- UniProtKB:	Q5PQV5 (UniProtKB/Swiss-Prot), Q9QYD9 (UniProtKB/Swiss-Prot), A6I1T6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPGAGSRGPSAGDGRLRLARLALVLLGWVSASAPSSSLPSSSTSPAAFLASGSAQPPPAERCPA ACECSEAARTVKCVNRNLLEVPADLPPYVRNLFLTGNQMTVLPAGAFARQPPLADLAVLNLSGN HLKEVGAGAFEHLPGLRRLDLSHNPLTNLSAFTFAGSNVSVSTPSPLLELILNHIVPPEDQRQN GSFEGMVAFEGMVAAALRSGLALRGLHHLELASNHFLYLPRDLLDQLPSLKHLDLRNNSLVSLT YASFRNLTHLESLHLEDNALKVLHNSTLAEWQGLAHVRVFLDNNPWVCDCYMADMVSWLKETEV VPDKARLTCAFPEKMRNRGLLDLTSSDLDCDATLPQSLQTSYVFLGIVLALIGAIFLLVLYLNR KGIKKWMHNIRDACRDHMEGYHYRYEINADPSLTNLSSNSDV hide sequence

RefSeq Acc Id:

XP_006243561 ⟸ XM_006243499

- Peptide Label:

isoform X1

- Sequence:

show sequence

MPGAGSRGPSAGDGRLRLARLALVLLGWVSASAPSSSLPSSSTSPAAFLASGSAQPPPAERCPA
ACECSEAARTVKCVNRNLLEVPADLPPYVRNLFLTGNQMTVLPAGAFARQPPLADLAVLNLSGN
HLKEVGAGAFEHLPGLRRLDLSHNPLTNLSAFTFAGSNVSVSTPSPLLELILNHIVPPEDQRQN
GSFEGMVAFEGMVAAALRSGLALRGLHHLELASNHFLYLPRDLLDQLPSLKHLDLRNNSLVSLT
YASFRNLTHLESLHLEDNALKVLHNSTLAEWQGLAHVRVFLDNNPWVCDCYMADMVSWLKETEV
VPDKARLTCAFPEKMRNRGLLDLTSSDLDCDATLPQSLQTSYVFLGIVLALIGAIFLLVLYLNR
KGIKKWMHNIRDACRDHMEGYHYRYEINADPRLTNLSSNSDV

hide sequence

RefSeq Acc Id:	XP_008764679 ⟸ XM_008766457
- Peptide Label:	isoform X1
- UniProtKB:	Q9QYD9 (UniProtKB/Swiss-Prot), Q5PQV5 (UniProtKB/Swiss-Prot), A6I1T6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPGAGSRGPSAGDGRLRLARLALVLLGWVSASAPSSSLPSSSTSPAAFLASGSAQPPPAERCPA ACECSEAARTVKCVNRNLLEVPADLPPYVRNLFLTGNQMTVLPAGAFARQPPLADLAVLNLSGN HLKEVGAGAFEHLPGLRRLDLSHNPLTNLSAFTFAGSNVSVSTPSPLLELILNHIVPPEDQRQN GSFEGMVAFEGMVAAALRSGLALRGLHHLELASNHFLYLPRDLLDQLPSLKHLDLRNNSLVSLT YASFRNLTHLESLHLEDNALKVLHNSTLAEWQGLAHVRVFLDNNPWVCDCYMADMVSWLKETEV VPDKARLTCAFPEKMRNRGLLDLTSSDLDCDATLPQSLQTSYVFLGIVLALIGAIFLLVLYLNR KGIKKWMHNIRDACRDHMEGYHYRYEINADPRLTNLSSNSDV hide sequence

RefSeq Acc Id:	XP_017451424 ⟸ XM_017595935
- Peptide Label:	isoform X1
- UniProtKB:	Q9QYD9 (UniProtKB/Swiss-Prot), Q5PQV5 (UniProtKB/Swiss-Prot), A6I1T6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPGAGSRGPSAGDGRLRLARLALVLLGWVSASAPSSSLPSSSTSPAAFLASGSAQPPPAERCPA ACECSEAARTVKCVNRNLLEVPADLPPYVRNLFLTGNQMTVLPAGAFARQPPLADLAVLNLSGN HLKEVGAGAFEHLPGLRRLDLSHNPLTNLSAFTFAGSNVSVSTPSPLLELILNHIVPPEDQRQN GSFEGMVAFEGMVAAALRSGLALRGLHHLELASNHFLYLPRDLLDQLPSLKHLDLRNNSLVSLT YASFRNLTHLESLHLEDNALKVLHNSTLAEWQGLAHVRVFLDNNPWVCDCYMADMVSWLKETEV VPDKARLTCAFPEKMRNRGLLDLTSSDLDCDATLPQSLQTSYVFLGIVLALIGAIFLLVLYLNR KGIKKWMHNIRDACRDHMEGYHYRYEINADPRLTNLSSNSDV hide sequence

Ensembl Acc Id:

ENSRNOP00000075124 ⟸ ENSRNOT00000089491

Ensembl Acc Id:

ENSRNOP00000014326 ⟸ ENSRNOT00000014326

Ensembl Acc Id:

ENSRNOP00000085521 ⟸ ENSRNOT00000104677

Ensembl Acc Id:

ENSRNOP00000099969 ⟸ ENSRNOT00000153056

Ensembl Acc Id:

ENSRNOP00000101915 ⟸ ENSRNOT00000130631

Ensembl Acc Id:

ENSRNOP00000100654 ⟸ ENSRNOT00000139740

Protein Domains

LRRCT LRRNT

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5PQV5-F1-model_v2	AlphaFold	Q5PQV5	1-426	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696159

Promoter ID:

EPDNEW_R6681

Type:

multiple initiation site

Name:

Tpbg_1

Description:

trophoblast glycoprotein

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	8	93,492,073 - 93,492,133	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621453	AgrOrtholog
BioCyc Gene	G2FUF-29645	BioCyc
Ensembl Genes	ENSRNOG00000010694	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000014326.3	UniProtKB/Swiss-Prot
	ENSRNOT00000089491.2	UniProtKB/Swiss-Prot
	ENSRNOT00000104677.1	UniProtKB/Swiss-Prot
	ENSRNOT00000130631	ENTREZGENE
	ENSRNOT00000139740	ENTREZGENE
	ENSRNOT00000153056	ENTREZGENE
Gene3D-CATH	3.80.10.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7193411	IMAGE-MGC_LOAD
InterPro	Cys-rich_flank_reg_C	UniProtKB/Swiss-Prot
	Leu-rich_rpt	UniProtKB/Swiss-Prot
	Leu-rich_rpt_typical-subtyp	UniProtKB/Swiss-Prot
	LRR_dom_sf	UniProtKB/Swiss-Prot
	LRRNT	UniProtKB/Swiss-Prot
	Wnt_signaling_inhibitor	UniProtKB/Swiss-Prot
KEGG Report	rno:83684	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93332	IMAGE-MGC_LOAD
NCBI Gene	83684	ENTREZGENE
PANTHER	LP06937P	UniProtKB/Swiss-Prot
	TROPHOBLAST GLYCOPROTEIN	UniProtKB/Swiss-Prot
Pfam	LRR_8	UniProtKB/Swiss-Prot
	LRRCT	UniProtKB/Swiss-Prot
	LRRNT	UniProtKB/Swiss-Prot
PhenoGen	Tpbg	PhenoGen
PRINTS	LEURICHRPT	UniProtKB/Swiss-Prot
PROSITE	LRR	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000010694	RatGTEx
SMART	LRR_TYP	UniProtKB/Swiss-Prot
	LRRCT	UniProtKB/Swiss-Prot
	LRRNT	UniProtKB/Swiss-Prot
Superfamily-SCOP	L domain-like	UniProtKB/Swiss-Prot
UniProt	A6I1T6	ENTREZGENE, UniProtKB/TrEMBL
	Q5PQV5	ENTREZGENE
	Q9QYD9	ENTREZGENE
	TPBG_RAT	UniProtKB/Swiss-Prot
UniProt Secondary	Q9QYD9	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-09-10	Tpbg	trophoblast glycoprotein			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Tpbg	trophoblast glycoprotein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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