Cox7a2 (cytochrome c oxidase subunit 7A2) - Rat Genome Database

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Gene: Cox7a2 (cytochrome c oxidase subunit 7A2) Rattus norvegicus
Analyze
Symbol: Cox7a2
Name: cytochrome c oxidase subunit 7A2
RGD ID: 68365
Description: Predicted to enable oxidoreductase activity. Predicted to be involved in mitochondrial respirasome assembly and regulation of oxidative phosphorylation. Predicted to be located in mitochondrial membrane. Predicted to be part of respiratory chain complex. Orthologous to several human genes including COX7A2 (cytochrome c oxidase subunit 7A2); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Cox7a3; cytochrome c oxidase polypeptide 7A2, mitochondrial; cytochrome c oxidase polypeptide VIIa-liver/heart; cytochrome c oxidase subunit 7A2, mitochondrial; cytochrome c oxidase subunit VIIa 3; cytochrome c oxidase subunit VIIa polypeptide 2; cytochrome c oxidase subunit VIIa-L; cytochrome c oxidase subunit VIIa-liver/heart; cytochrome c oxidase, subunit 7a 3; cytochrome c oxidase, subunit VIIa 2; cytochrome c oxidase, subunit VIIa 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8889,597,051 - 89,611,032 (-)NCBIGRCr8
mRatBN7.2880,716,824 - 80,720,922 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl880,716,825 - 80,720,264 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1451,301,168 - 51,301,633 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx886,243,328 - 86,247,447 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0884,520,473 - 84,524,593 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0882,343,104 - 82,347,224 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0887,209,529 - 87,213,627 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl887,209,530 - 87,213,627 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0886,753,411 - 86,757,509 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4884,813,292 - 84,817,390 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1884,832,748 - 84,836,813 (-)NCBI
Celera880,441,572 - 80,445,670 (-)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
ampicillin  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenic trichloride  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
Benoxacor  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
cadmium atom  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
clofibric acid  (EXP)
clotrimazole  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
corosolic acid  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
dibutyl phthalate  (EXP,ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
epoxiconazole  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
isoniazide  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
linuron  (EXP)
lipopolysaccharide  (ISO)
maneb  (ISO)
methimazole  (EXP)
metronidazole  (EXP)
N-nitrosodiethylamine  (EXP)
neomycin  (EXP)
oxybenzone  (EXP)
paracetamol  (ISO)
paraquat  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenethyl caffeate  (EXP)
PhIP  (EXP)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP)
titanium dioxide  (ISO)
tolcapone  (EXP)
toluene  (EXP)
Tributyltin oxide  (EXP)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
vinclozolin  (EXP)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Nucleotide sequence of cDNA encoding subunit VIIa of rat liver cytochrome c oxidase. Enders C, etal., Nucleic Acids Res 1990 Dec 11;18(23):7143.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:2175025   PMID:7601105   PMID:8889548   PMID:12060780   PMID:12477932   PMID:12865426   PMID:14651853   PMID:18614015   PMID:23376485   PMID:29476059   PMID:30030519   PMID:34800366  


Genomics

Comparative Map Data
Cox7a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8889,597,051 - 89,611,032 (-)NCBIGRCr8
mRatBN7.2880,716,824 - 80,720,922 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl880,716,825 - 80,720,264 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1451,301,168 - 51,301,633 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx886,243,328 - 86,247,447 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0884,520,473 - 84,524,593 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0882,343,104 - 82,347,224 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0887,209,529 - 87,213,627 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl887,209,530 - 87,213,627 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0886,753,411 - 86,757,509 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4884,813,292 - 84,817,390 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1884,832,748 - 84,836,813 (-)NCBI
Celera880,441,572 - 80,445,670 (-)NCBICelera
Cytogenetic Map8q31NCBI
COX7A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38675,237,675 - 75,250,298 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl675,237,675 - 75,250,323 (-)EnsemblGRCh38hg38GRCh38
GRCh37675,947,391 - 75,960,014 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36676,004,223 - 76,010,245 (-)NCBINCBI36Build 36hg18NCBI36
Build 34676,004,222 - 76,010,245NCBI
Celera676,341,126 - 76,347,377 (-)NCBICelera
Cytogenetic Map6q14.1NCBI
HuRef673,146,540 - 73,152,778 (-)NCBIHuRef
CHM1_1676,113,807 - 76,120,050 (-)NCBICHM1_1
T2T-CHM13v2.0676,414,841 - 76,427,128 (-)NCBIT2T-CHM13v2.0
Cox7a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39979,662,523 - 79,667,135 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl979,662,643 - 79,667,160 (-)EnsemblGRCm39 Ensembl
GRCm38979,755,241 - 79,771,422 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl979,755,361 - 79,759,878 (-)EnsemblGRCm38mm10GRCm38
MGSCv37979,603,048 - 79,607,660 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36979,540,925 - 79,545,537 (-)NCBIMGSCv36mm8
Celera976,900,017 - 76,905,817 (-)NCBICelera
Cytogenetic Map9E1NCBI
cM Map943.82NCBI
LOC102029536
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555023,753,029 - 3,759,663 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555023,753,029 - 3,759,663 (-)NCBIChiLan1.0ChiLan1.0
LOC100981677
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2595,284,587 - 95,296,753 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1693,162,355 - 93,174,537 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0673,080,762 - 73,092,922 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1676,372,094 - 76,377,903 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl676,372,094 - 76,377,903 (-)Ensemblpanpan1.1panPan2
LOC100686500
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1829,140,982 - 29,142,680 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha828,886,608 - 28,886,900 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0829,305,305 - 29,305,793 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1828,982,787 - 28,983,079 (+)NCBIUMICH_Zoey_3.1
UU_Cfam_GSD_1.0829,383,827 - 29,384,119 (+)NCBIUU_Cfam_GSD_1.0
LOC101966864
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494672,297,526 - 72,304,695 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936788679,717 - 686,841 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COX7A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl190,696,698 - 90,703,409 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1190,696,746 - 90,703,407 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21101,816,761 - 101,823,433 (-)NCBISscrofa10.2Sscrofa10.2susScr3
COX7A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11745,771 - 51,466 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1745,771 - 51,669 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660585,857,739 - 5,863,586 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101723434
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248192,248,826 - 2,256,080 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248192,249,831 - 2,255,915 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cox7a2
16 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:33
Count of miRNA genes:30
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000066084
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85009524982460899Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83084815482460899Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
737824Hcar10Hepatocarcinoma resistance QTL 102.9liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)84071306682925667Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84071306693965294Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)87531177784531599Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)82720571599103503Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
1582254Kidm31Kidney mass QTL 313kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)85423764485365202Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)82720571599103503Rat
5684973Bss100Bone structure and strength QTL 1004.7tibia area (VT:1000281)tibia area measurement (CMO:0001382)85009524982460899Rat
1582243Bw66Body weight QTL 663.40.0048body mass (VT:0001259)body weight (CMO:0000012)85423764485365202Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83084815482460899Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)84329616998968765Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)854259986100382532Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)83018886794457446Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)84329616998968765Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83084815482460899Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)84329616998968765Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)84329616998968765Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)84329616998968765Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)84329616998968765Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)851351728107062046Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)87531193882925521Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
2313086Bss60Bone structure and strength QTL 604.10.0001tibia length (VT:0004357)tibia length (CMO:0000450)85009524982460899Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)85404374498968765Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)84653172299083736Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83646953599083736Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat
2303570Gluco48Glucose level QTL 482blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)84980583194805831Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83084815482460899Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)85423764499103503Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat

Markers in Region
RH127632  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21451,301,188 - 51,301,397 (+)MAPPERmRatBN7.2
Rnor_6.01452,661,952 - 52,662,160NCBIRnor6.0
Rnor_5.01452,813,680 - 52,813,888UniSTSRnor5.0
RGSC_v3.41455,352,593 - 55,352,801UniSTSRGSC3.4
Celera1450,506,143 - 50,506,351UniSTS
RH 3.4 Map21228.8UniSTS
Cytogenetic Map14q11UniSTS
Cytogenetic Map8q24-q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
3 11 43 82 57 60 41 19 41 160 73 74 35 41 19

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_022503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC108529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW521400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC166880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG668415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X54080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: NM_022503   ⟹   NP_071948
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8889,597,051 - 89,601,149 (-)NCBI
mRatBN7.2880,716,824 - 80,720,922 (-)NCBI
Rnor_6.0887,209,529 - 87,213,627 (-)NCBI
Rnor_5.0886,753,411 - 86,757,509 (-)NCBI
RGSC_v3.4884,813,292 - 84,817,390 (-)RGD
Celera880,441,572 - 80,445,670 (-)RGD
Sequence:
RefSeq Acc Id: XM_063265016   ⟹   XP_063121086
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8889,597,053 - 89,611,032 (-)NCBI
RefSeq Acc Id: XM_063265017   ⟹   XP_063121087
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8889,597,053 - 89,611,032 (-)NCBI
RefSeq Acc Id: NP_071948   ⟸   NM_022503
- Peptide Label: precursor
- UniProtKB: P35171 (UniProtKB/Swiss-Prot),   B2RYS0 (UniProtKB/TrEMBL),   A0A8L2QTB7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_063121087   ⟸   XM_063265017
- Peptide Label: isoform X2
- UniProtKB: P35171 (UniProtKB/Swiss-Prot),   B2RYS0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121086   ⟸   XM_063265016
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P35171-F1-model_v2 AlphaFold P35171 1-83 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696148
Promoter ID:EPDNEW_R6673
Type:initiation region
Name:Cox7a2l2_1
Description:cytochrome c oxidase subunit VIIa polypeptide 2-like 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0887,213,594 - 87,213,654EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:68365 AgrOrtholog
BioCyc Gene G2FUF-29740 BioCyc
BioCyc Pathway PWY-3781 [aerobic respiration I (cytochrome c)] BioCyc
  PWY-7279 [aerobic respiration II (cytochrome c) (yeast)] BioCyc
BioCyc Pathway Image PWY-3781 BioCyc
  PWY-7279 BioCyc
Ensembl Genes ENSRNOG00000027791 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00000042903 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000038497.6 UniProtKB/Swiss-Prot
  ENSRNOT00000066084.2 UniProtKB/TrEMBL
Gene3D-CATH 4.10.91.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6888806 IMAGE-MGC_LOAD
InterPro COX7a UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_c_oxidase_su7a_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cytc_oxidase_su7a_met UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29507 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  rno:688386 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:188812 IMAGE-MGC_LOAD
NCBI Gene 29507 ENTREZGENE
PANTHER CYTOCHROME C OXIDASE SUBUNIT 7A2, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10510 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam COX7a UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cox7a2 PhenoGen
RatGTEx ENSRNOG00000027791 RatGTEx
  ENSRNOG00000042903 RatGTEx
Superfamily-SCOP SSF81419 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC204335
UniProt A0A8L2QTB7 ENTREZGENE, UniProtKB/TrEMBL
  B2RYS0 ENTREZGENE, UniProtKB/TrEMBL
  CX7A2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-05 Cox7a2  cytochrome c oxidase subunit 7A2  Cox7a2  cytochrome c oxidase subunit VIIa polypeptide 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-12-15 Cox7a2  cytochrome c oxidase subunit VIIa polypeptide 2  Cox7a2  cytochrome c oxidase, subunit VIIa 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Cox7a2  cytochrome c oxidase, subunit VIIa 2      Symbol and Name updated 1299863 APPROVED
2002-06-10 Cox7a3  cytochrome c oxidase, subunit 7a 3      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference