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Gene: Mapk6 (mitogen-activated protein kinase 6) Rattus norvegicus
Symbol: Mapk6
Name: mitogen-activated protein kinase 6
Description: Predicted to have MAP kinase activity; protein heterodimerization activity; and protein kinase binding activity. Predicted to be involved in several processes, including intracellular signal transduction; positive regulation of dendritic spine development; and protein phosphorylation. Predicted to localize to several cellular components, including the cytosol; nucleus; and septin cytoskeleton. Orthologous to human MAPK6 (mitogen-activated protein kinase 6); INTERACTS WITH 2,4,6-trinitrobenzenesulfonic acid; 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ERK-3; ERK3; extracellular signal-regulated kinase 3; MAP kinase 6; MAPK 6; MGC124957; p55-MAPK
Homo sapiens (human) : MAPK6 (mitogen-activated protein kinase 6)  HGNC  Alliance
Mus musculus (house mouse) : Mapk6 (mitogen-activated protein kinase 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mapk6 (mitogen-activated protein kinase 6)
Pan paniscus (bonobo/pygmy chimpanzee) : MAPK6 (mitogen-activated protein kinase 6)
Canis lupus familiaris (dog) : MAPK6 (mitogen-activated protein kinase 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mapk6 (mitogen-activated protein kinase 6)
Sus scrofa (pig) : MAPK6 (mitogen-activated protein kinase 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0882,328,013 - 82,351,108 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0881,931,183 - 81,954,196 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4880,212,726 - 80,236,362 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1880,231,926 - 80,243,701 (-)NCBI
Celera875,936,355 - 75,959,409 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Mapk6
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62087
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-07-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.