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Gene: Hyou1 (hypoxia up-regulated 1) Rattus norvegicus
Symbol: Hyou1
Name: hypoxia up-regulated 1
Description: Predicted to have ATP binding activity and chaperone binding activity. Involved in negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway and response to hypoxia. Localizes to the smooth endoplasmic reticulum. Orthologous to human HYOU1 (hypoxia up-regulated 1); PARTICIPATES IN codeine and morphine pharmacodynamics pathway; codeine and morphine pharmacokinetics pathway; etoposide pharmacodynamics pathway; INTERACTS WITH 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 150 kDa oxygen-regulated protein; Cab140; hypoxia up-regulated protein 1; ORP-150; Orp150; oxygen regulated protein (150kD)
Homo sapiens (human) : HYOU1 (hypoxia up-regulated 1)  HGNC  Alliance
Mus musculus (house mouse) : Hyou1 (hypoxia up-regulated 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hyou1 (hypoxia up-regulated 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HYOU1 (hypoxia up-regulated 1)
Canis lupus familiaris (dog) : HYOU1 (hypoxia up-regulated 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hyou1 (hypoxia up-regulated 1)
Sus scrofa (pig) : HYOU1 (hypoxia up-regulated 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0848,699,796 - 48,711,912 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0847,318,767 - 47,330,883 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4847,346,753 - 47,358,869 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1847,355,708 - 47,366,413 (+)NCBI
Celera844,292,303 - 44,304,419 (+)NCBICelera
Cytogenetic Map8q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Hyou1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621146
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-05-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.