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Gene: Htr3a (5-hydroxytryptamine receptor 3A) Rattus norvegicus
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Symbol: Htr3a
Name: 5-hydroxytryptamine receptor 3A
Description: Exhibits serotonin-gated cation-selective channel activity. Predicted to contribute to extracellular ligand-gated ion channel activity. Involved in several processes, including positive regulation of ion transmembrane transporter activity; response to cocaine; and response to ethanol. Localizes to several cellular components, including the glutamatergic synapse; integral component of synaptic membrane; and neuronal cell body. Human ortholog(s) of this gene implicated in dyspepsia and irritable bowel syndrome. Orthologous to human HTR3A (5-hydroxytryptamine receptor 3A); INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 1-bromopropane; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 5-HT-3; 5-HT3; 5-HT3 receptor; 5-HT3-A; 5-HT3A; 5-HT3R; 5-hydroxytryptamine (serotonin) receptor 3a; 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic; 5-hydroxytryptamine receptor 3; 5HT3; 5HT3 receptor; Htr3; serotonin receptor 3A; serotonin-gated ion channel receptor
Orthologs:
Homo sapiens (human) : HTR3A (5-hydroxytryptamine receptor 3A)  HGNC  Alliance
Mus musculus (house mouse) : Htr3a (5-hydroxytryptamine (serotonin) receptor 3A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Htr3a (5-hydroxytryptamine receptor 3A)
Pan paniscus (bonobo/pygmy chimpanzee) : HTR3A (5-hydroxytryptamine receptor 3A)
Canis lupus familiaris (dog) : HTR3A (5-hydroxytryptamine receptor 3A)
Sus scrofa (pig) : HTR3A (5-hydroxytryptamine receptor 3A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0853,211,436 - 53,223,878 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0851,803,895 - 51,816,278 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4852,161,147 - 52,173,514 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1852,180,200 - 52,192,425 (-)NCBI
Celera848,799,808 - 48,812,052 (-)NCBICelera
Cytogenetic Map8q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Htr3a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61818
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.