Gene: Loxl1 (lysyl oxidase-like 1) Rattus norvegicus
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Symbol: Loxl1
Name: lysyl oxidase-like 1
Description: ENCODES a protein that exhibits oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor (ortholog); INVOLVED IN aorta development; response to lipopolysaccharide; ASSOCIATED WITH Cardiomegaly; Choroidal Neovascularization (ortholog); Kuhnt-Junius degeneration (ortholog); FOUND IN acrosomal vesicle; basement membrane; cytoplasm; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine
AGR Description: Predicted to have protein-lysine 6-oxidase activity; involved in aorta development and response to lipopolysaccharide; localizes to the acrosomal vesicle and basement membrane; orthologous to human LOXL1 (lysyl oxidase like 1).
Merged Description: Predicted to have protein-lysine 6-oxidase activity; involved in aorta development and response to lipopolysaccharide; localizes to the acrosomal vesicle and basement membrane; orthologous to human LOXL1 (lysyl oxidase like 1); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC315714; lysyl oxidase homolog 1; MGC105563
Orthologs:
Homo sapiens (human) : LOXL1 (lysyl oxidase like 1)  HGNC  Alliance
Mus musculus (house mouse) : Loxl1 (lysyl oxidase-like 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Loxl1 (lysyl oxidase like 1)
Canis lupus familiaris (dog) : LOXL1 (lysyl oxidase like 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Loxl1 (lysyl oxidase like 1)
Sus scrofa (pig) : LOXL1 (lysyl oxidase like 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0863,067,757 - 63,092,124 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0862,843,790 - 62,868,157 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4862,083,052 - 62,106,827 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1862,102,104 - 62,125,881 (-)NCBI
Celera858,155,183 - 58,178,908 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

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Genomics

Comparative Map Data
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QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
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Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
  
More on Loxl1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308752
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.