Gene: Loxl1 (lysyl oxidase-like 1) Rattus norvegicus
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Symbol: Loxl1
Name: lysyl oxidase-like 1
Description: ENCODES a protein that exhibits oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor (ortholog); INVOLVED IN aorta development; response to lipopolysaccharide; ASSOCIATED WITH Cardiomegaly; Choroidal Neovascularization (ortholog); Kuhnt-Junius degeneration (ortholog); FOUND IN acrosomal vesicle; basement membrane; cytoplasm; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine
AGR Description: Predicted to have protein-lysine 6-oxidase activity; involved in aorta development and response to lipopolysaccharide; localizes to the acrosomal vesicle and basement membrane; orthologous to human LOXL1 (lysyl oxidase like 1).
Merged Description: Predicted to have protein-lysine 6-oxidase activity; involved in aorta development and response to lipopolysaccharide; localizes to the acrosomal vesicle and basement membrane; orthologous to human LOXL1 (lysyl oxidase like 1); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC315714; lysyl oxidase homolog 1; MGC105563
Orthologs:
Homo sapiens (human) : LOXL1 (lysyl oxidase like 1)  HGNC  Alliance
Mus musculus (house mouse) : Loxl1 (lysyl oxidase-like 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Loxl1 (lysyl oxidase like 1)
Canis lupus familiaris (dog) : LOXL1 (lysyl oxidase like 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Loxl1 (lysyl oxidase like 1)
Sus scrofa (pig) : LOXL1 (lysyl oxidase like 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0863,067,757 - 63,092,124 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0862,843,790 - 62,868,157 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4862,083,052 - 62,106,827 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1862,102,104 - 62,125,881 (-)NCBI
Celera858,155,183 - 58,178,908 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Loxl1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308752
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.