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Gene: Sdhd (succinate dehydrogenase complex subunit D) Rattus norvegicus
Symbol: Sdhd
Name: succinate dehydrogenase complex subunit D
RGD ID: 735231
Description: Predicted to have heme binding activity; succinate dehydrogenase (ubiquinone) activity; and ubiquinone binding activity. Predicted to be involved in cellular respiration; cellular response to hypoxia; and regulation of catecholamine secretion. Predicted to localize to mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone). Human ortholog(s) of this gene implicated in Carney-Stratakis syndrome; mitochondrial complex II deficiency; paraganglioma; and pheochromocytoma. Orthologous to human SDHD (succinate dehydrogenase complex subunit D); PARTICIPATES IN altered citric acid cycle pathway; citric acid cycle pathway; electron transport chain pathway; INTERACTS WITH (+)-schisandrin B; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil.
Type: protein-coding
Also known as: CII-4; cybS; MGC72971; QPs3; succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; succinate dehydrogenase complex, subunit D, integral membrane protein; succinate-ubiquinone oxidoreductase cytochrome b small subunit; succinate-ubiquinone reductase membrane anchor subunit
Homo sapiens (human) : SDHD (succinate dehydrogenase complex subunit D)  HGNC  Alliance
Mus musculus (house mouse) : Sdhd (succinate dehydrogenase complex, subunit D, integral membrane protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sdhd (succinate dehydrogenase complex subunit D)
Pan paniscus (bonobo/pygmy chimpanzee) : SDHD (succinate dehydrogenase complex subunit D)
Canis lupus familiaris (dog) : SDHD (succinate dehydrogenase complex subunit D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sdhd (succinate dehydrogenase complex subunit D)
Sus scrofa (pig) : SDHD (succinate dehydrogenase complex subunit D)
Chlorocebus sabaeus (African green monkey) : SDHD (succinate dehydrogenase complex subunit D)
Heterocephalus glaber (naked mole-rat) : Sdhd (succinate dehydrogenase complex subunit D)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0855,028,125 - 55,037,604 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl855,028,125 - 55,037,604 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0853,625,447 - 53,634,926 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4853,955,067 - 53,964,547 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1853,974,120 - 53,983,601 (-)NCBI
Celera850,493,184 - 50,502,624 (-)NCBICelera
Cytogenetic Map8q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Sdhd
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735231
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.