Mto1 (mitochondrial tRNA translation optimization 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Mto1 (mitochondrial tRNA translation optimization 1) Rattus norvegicus
Analyze
Symbol: Mto1
Name: mitochondrial tRNA translation optimization 1
RGD ID: 1308830
Description: Predicted to enable flavin adenine dinucleotide binding activity. Predicted to be involved in mitochondrial tRNA wobble uridine modification and tRNA methylation. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 10. Orthologous to human MTO1 (mitochondrial tRNA translation optimization 1); INTERACTS WITH 2,6-dinitrotoluene; 3-chloropropane-1,2-diol; 7,12-dimethyltetraphene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC300852; mitochondrial translation optimization 1 homolog; mitochondrial translation optimization 1 homolog (S. cerevisiae); protein MTO1 homolog, mitochondrial
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2879,309,681 - 79,335,231 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl879,309,982 - 79,335,231 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx884,839,709 - 84,865,096 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0883,116,858 - 83,142,241 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0880,939,545 - 80,964,930 (+)NCBIRnor_WKY
Rnor_6.0885,807,703 - 85,832,263 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl885,808,125 - 85,831,937 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0885,357,705 - 85,381,551 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4883,444,213 - 83,457,260 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1883,372,221 - 83,476,311 (+)NCBI
Celera879,057,065 - 79,081,337 (+)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
mitochondrion  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14522080   PMID:18614015   PMID:22681889   PMID:32157506  


Genomics

Comparative Map Data
Mto1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2879,309,681 - 79,335,231 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl879,309,982 - 79,335,231 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx884,839,709 - 84,865,096 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0883,116,858 - 83,142,241 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0880,939,545 - 80,964,930 (+)NCBIRnor_WKY
Rnor_6.0885,807,703 - 85,832,263 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl885,808,125 - 85,831,937 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0885,357,705 - 85,381,551 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4883,444,213 - 83,457,260 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1883,372,221 - 83,476,311 (+)NCBI
Celera879,057,065 - 79,081,337 (+)NCBICelera
Cytogenetic Map8q31NCBI
MTO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38673,461,737 - 73,509,236 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl673,461,578 - 73,509,236 (+)EnsemblGRCh38hg38GRCh38
GRCh37674,171,460 - 74,218,959 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36674,228,209 - 74,267,896 (+)NCBINCBI36Build 36hg18NCBI36
Celera674,565,658 - 74,605,390 (+)NCBICelera
Cytogenetic Map6q13NCBI
HuRef671,369,741 - 71,410,063 (+)NCBIHuRef
CHM1_1674,338,243 - 74,377,999 (+)NCBICHM1_1
T2T-CHM13v2.0674,638,132 - 74,686,339 (+)NCBIT2T-CHM13v2.0
Mto1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39978,355,372 - 78,381,447 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl978,355,490 - 78,382,630 (+)EnsemblGRCm39 Ensembl
GRCm38978,443,479 - 78,474,165 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl978,448,208 - 78,475,348 (+)EnsemblGRCm38mm10GRCm38
MGSCv37978,296,017 - 78,321,959 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36978,233,904 - 78,259,836 (+)NCBIMGSCv36mm8
Celera975,626,365 - 75,652,703 (+)NCBICelera
Cytogenetic Map9E1NCBI
Mto1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554938,636,110 - 8,649,721 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554938,636,093 - 8,655,090 (+)NCBIChiLan1.0ChiLan1.0
MTO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1674,570,849 - 74,612,567 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl674,570,890 - 74,612,567 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0671,282,988 - 71,325,075 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
MTO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11235,533,766 - 35,563,058 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1235,533,808 - 35,560,593 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1235,405,010 - 35,434,313 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01236,090,861 - 36,120,181 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1236,090,892 - 36,122,136 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11235,630,018 - 35,657,430 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01235,651,760 - 35,680,976 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01235,775,710 - 35,805,208 (+)NCBIUU_Cfam_GSD_1.0
Mto1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494670,822,149 - 70,852,299 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936859740,281 - 788,435 (-)EnsemblSpeTri2.0
SpeTri2.0NW_004936859757,977 - 788,073 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MTO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl192,447,164 - 92,483,236 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1192,447,156 - 92,472,488 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21103,499,924 - 103,525,326 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MTO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1171,650,818 - 1,688,362 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl171,651,011 - 1,688,321 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660587,556,648 - 7,600,439 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mto1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624819687,050 - 722,993 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624819686,759 - 729,765 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mto1
170 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:27
Count of miRNA genes:27
Interacting mature miRNAs:27
Transcripts:ENSRNOT00000057138
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)82720571599103503Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)82720571599103503Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)83018886794457446Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83084815482460899Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83084815482460899Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83084815482460899Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83084815482460899Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83555193880551938Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83646953599083736Rat
737824Hcar10Hepatocarcinoma resistance QTL 102.9liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)84071306682925667Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84071306693965294Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)84329616998968765Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)84329616998968765Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)84329616998968765Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)84329616998968765Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)84329616998968765Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)84329616998968765Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088624Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)84653172299083736Rat
2303570Gluco48Glucose level QTL 482blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)84980583194805831Rat
2313086Bss60Bone structure and strength QTL 604.10.0001tibia length (VT:0004357)tibia length (CMO:0000450)85009524982460899Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85009524982460899Rat
5684973Bss100Bone structure and strength QTL 1004.7tibia area (VT:1000281)tibia area measurement (CMO:0001382)85009524982460899Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)851351728107062046Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)85404374498968765Rat
1582243Bw66Body weight QTL 663.40.0048body mass (VT:0001259)body weight (CMO:0000012)85423764485365202Rat
1582254Kidm31Kidney mass QTL 313kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)85423764485365202Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)85423764499103503Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)854259986100382532Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)87531177784531599Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)87531193882925521Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat

Markers in Region
RH143356  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2879,311,334 - 79,311,648 (+)MAPPERmRatBN7.2
Rnor_6.0885,809,394 - 85,809,707NCBIRnor6.0
Rnor_5.0885,359,058 - 85,359,371UniSTSRnor5.0
Celera879,058,418 - 79,058,731UniSTS
RH 3.4 Map8925.4UniSTS
Cytogenetic Map8q31UniSTS
AW532304  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2879,310,036 - 79,310,198 (+)MAPPERmRatBN7.2
Rnor_6.0885,808,096 - 85,808,257NCBIRnor6.0
Rnor_5.0885,357,760 - 85,357,921UniSTSRnor5.0
Celera879,057,120 - 79,057,281UniSTS
RH 3.4 Map8924.4UniSTS
Cytogenetic Map8q31UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 29 31 16 13 16 4 7 74 35 33 10 4
Low 1 14 26 25 6 25 4 4 8 1 4
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000057138   ⟹   ENSRNOP00000053966
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl879,309,982 - 79,335,231 (+)Ensembl
Rnor_6.0 Ensembl885,808,125 - 85,831,937 (+)Ensembl
RefSeq Acc Id: NM_001106841   ⟹   NP_001100311
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2879,309,982 - 79,335,231 (+)NCBI
Rnor_6.0885,808,041 - 85,832,263 (+)NCBI
Rnor_5.0885,357,705 - 85,381,551 (+)NCBI
RGSC_v3.4883,444,213 - 83,457,260 (+)RGD
Celera879,057,065 - 79,081,337 (+)RGD
Sequence:
RefSeq Acc Id: XM_039081156   ⟹   XP_038937084
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2879,309,681 - 79,335,228 (+)NCBI
RefSeq Acc Id: XM_039081157   ⟹   XP_038937085
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2879,311,364 - 79,335,228 (+)NCBI
RefSeq Acc Id: XM_039081158   ⟹   XP_038937086
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2879,309,681 - 79,320,953 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001100311 (Get FASTA)   NCBI Sequence Viewer  
  XP_038937084 (Get FASTA)   NCBI Sequence Viewer  
  XP_038937085 (Get FASTA)   NCBI Sequence Viewer  
  XP_038937086 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL77729 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001100311   ⟸   NM_001106841
- UniProtKB: F1LYH3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000053966   ⟸   ENSRNOT00000057138
RefSeq Acc Id: XP_038937084   ⟸   XM_039081156
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038937086   ⟸   XM_039081158
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038937085   ⟸   XM_039081157
- Peptide Label: isoform X2
Protein Domains
GIDA   GIDA_C

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LYH3-F1-model_v2 AlphaFold F1LYH3 1-661 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696145
Promoter ID:EPDNEW_R6670
Type:initiation region
Name:Mto1_1
Description:mitochondrial tRNA translation optimization 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0885,808,040 - 85,808,100EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308830 AgrOrtholog
BioCyc Gene G2FUF-29756 BioCyc
BioCyc Pathway PWY-7889 [tRNA-uridine 2-thiolation (mammalian mitochondria)] BioCyc
Ensembl Genes ENSRNOG00000037659 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000053966 ENTREZGENE
  ENSRNOP00000053966.5 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000057138 ENTREZGENE
  ENSRNOT00000057138.5 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.570 UniProtKB/TrEMBL
  3.50.50.60 UniProtKB/TrEMBL
InterPro FAD/NAD-bd_sf UniProtKB/TrEMBL
  GidA UniProtKB/TrEMBL
  GidA-assoc_3 UniProtKB/TrEMBL
  GIDA-rel UniProtKB/TrEMBL
  GIDA-rel_CS UniProtKB/TrEMBL
  MnmG_C_subdom UniProtKB/TrEMBL
  MnmG_N UniProtKB/TrEMBL
NCBI Gene 300852 ENTREZGENE
PANTHER PTHR11806 UniProtKB/TrEMBL
  PTHR11806:SF0 UniProtKB/TrEMBL
Pfam GIDA UniProtKB/TrEMBL
  GIDA_assoc_3 UniProtKB/TrEMBL
PhenoGen Mto1 PhenoGen
PROSITE GIDA_1 UniProtKB/TrEMBL
  GIDA_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF51905 UniProtKB/TrEMBL
TIGRFAMs gidA UniProtKB/TrEMBL
UniProt F1LYH3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-15 Mto1  mitochondrial tRNA translation optimization 1  Mto1  mitochondrial translation optimization 1 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Mto1  mitochondrial translation optimization 1 homolog (S. cerevisiae)   Mto1_predicted  mitochondrial translation optimization 1 homolog (S. cerevisiae) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Mto1_predicted  mitochondrial translation optimization 1 homolog (S. cerevisiae) (predicted)      Symbol and Name status set to approved 70820 APPROVED