Gene: Gsta2 (glutathione S-transferase alpha 2) Rattus norvegicus
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Symbol: Gsta2
Name: glutathione S-transferase alpha 2
Description: ENCODES a protein that exhibits drug binding; glutathione binding; glutathione transferase activity; INVOLVED IN aging; xenobiotic catabolic process; epithelial cell differentiation (ortholog); PARTICIPATES IN glutathione conjugation pathway; glutathione metabolic pathway; phase I biotransformation pathway via cytochrome P450; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN cytosol; nuclear outer membrane; nucleus; INTERACTS WITH 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol
AGR Description: Exhibits several functions, including drug binding activity, glutathione binding activity, and glutathione transferase activity; involved in aging and xenobiotic catabolic process; localizes to the cytosol and nuclear outer membrane; orthologous to several human genes including GSTA1 (glutathione S-transferase alpha 1), GSTA2 (glutathione S-transferase alpha 2), and GSTA3 (glutathione S-transferase alpha 3).
Merged Description: Exhibits several functions, including drug binding activity, glutathione binding activity, and glutathione transferase activity; involved in aging and xenobiotic catabolic process; localizes to the cytosol and nuclear outer membrane; orthologous to several human genes including GSTA1 (glutathione S-transferase alpha 1), GSTA2 (glutathione S-transferase alpha 2), and GSTA3 (glutathione S-transferase alpha 3); PARTICIPATES IN glutathione conjugation pathway; glutathione metabolic pathway; phase I biotransformation pathway via cytochrome P450; INTERACTS WITH 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: glutathione S-transferase A2; glutathione S-transferase alpha-1; glutathione S-transferase Ya subunit; glutathione S-transferase Ya-1; glutathione S-transferase, alpha 2; Glutathione-S-transferase alpha type (Yc?); Glutathione-S-transferase, alpha type (Yc?); glutathione-S-transferase, alpha type2; GST 1-1; GST 1a-1a; GST A1-1; GST B; GST Ya1; Gsta1; ligandin
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0885,640,081 - 85,645,621 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0885,197,052 - 85,202,588 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4883,299,249 - 83,312,958 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1883,318,303 - 83,332,012 (-)NCBI
Celera878,931,925 - 78,944,156 (-)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gsta2
Alliance Gene
NCBI Gene
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JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2754
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.