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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2754
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gsta2
Name: glutathione S-transferase alpha 2
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gsta2decreases expressionEXP 6480464CTDLipopolysaccharides results in decreased expression of GSTA2 mRNAPMID:14561216
Gsta2multiple interactionsEXP 6480464CTDLipopolysaccharides inhibits the reaction [HNF1A protein binds to GSTA2 promoter]; Lipopolysaccharides inhibits the reaction [USP3 protein binds to GSTA2 promoter]PMID:14561216
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