Elovl5 (ELOVL fatty acid elongase 5) - Rat Genome Database

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Gene: Elovl5 (ELOVL fatty acid elongase 5) Rattus norvegicus
Analyze
Symbol: Elovl5
Name: ELOVL fatty acid elongase 5
RGD ID: 620583
Description: Enables fatty acid elongase activity. Involved in fatty acid elongation, polyunsaturated fatty acid and very long-chain fatty acid biosynthetic process. Predicted to be located in dendritic tree; endoplasmic reticulum; and neuronal cell body. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 38. Orthologous to human ELOVL5 (ELOVL fatty acid elongase 5); PARTICIPATES IN alpha-linolenic acid metabolic pathway; linoleic acid metabolic pathway; unsaturated fatty acid biosynthetic pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 3-keto acyl-CoA synthase Elovl5; elongation of long chain fatty acids family member 5; elongation of very long chain fatty acids protein 5; elongation of very long chain fatty acids-like 5; ELOVL FA elongase 5; ELOVL family member 5, elongation of long chain fatty acids; ELOVL family member 5, elongation of long chain fatty acids (yeast); fatty acid elongase 1; rELO1; very long chain 3-ketoacyl-CoA synthase 5; very long chain 3-oxoacyl-CoA synthase 5; very long chain fatty acid elongase 5; very-long-chain 3-oxoacyl-CoA synthase 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8887,671,164 - 87,737,618 (+)NCBIGRCr8
mRatBN7.2878,790,846 - 78,857,307 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl878,790,846 - 78,857,284 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx884,316,763 - 84,342,848 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0882,593,410 - 82,619,495 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0880,416,122 - 80,442,207 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0885,220,941 - 85,287,449 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl885,259,982 - 85,285,983 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0884,786,562 - 84,853,064 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4882,922,551 - 82,948,348 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1882,941,604 - 82,967,402 (+)NCBI
Celera878,575,885 - 78,600,766 (+)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
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Original Reference(s)
Elovl5Ratatherosclerosis treatmentISOElovl5 (Mus musculus)401827839 RGD 
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Original Reference(s)
Elovl5Ratgenetic disease  ISOELOVL5 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 and PMID:28492532
Elovl5Ratmyoepithelioma  ISOELOVL5 (Homo sapiens)8554872ClinVar Annotator: match by term: Myoepithelial tumorClinVar 
Elovl5Ratspinocerebellar ataxia type 38  ISOELOVL5 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25065913 more ...
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Original Reference(s)
Elovl5RatExperimental Liver Cirrhosis  ISOELOVL5 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25380136
Elovl5RatSpinocerebellar Ataxias  ISOELOVL5 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
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Original Reference(s)
Elovl5Ratspinocerebellar ataxia type 38  ISOELOVL5 (Homo sapiens)7240710 OMIM 

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Original Reference(s)
Elovl5Rat(1->4)-beta-D-glucan multiple interactionsISOElovl5 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ELOVL5 mRNACTDPMID:36331819
Elovl5Rat1,2-dimethylhydrazine multiple interactionsISOElovl5 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ELOVL5 mRNACTDPMID:22206623
Elovl5Rat1,2-dimethylhydrazine decreases expressionISOElovl5 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of ELOVL5 mRNACTDPMID:22206623
Elovl5Rat1-naphthyl isothiocyanate decreases expressionEXP 64804641-Naphthylisothiocyanate results in decreased expression of ELOVL5 mRNACTDPMID:25380136
Elovl5Rat17alpha-ethynylestradiol multiple interactionsISOElovl5 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ELOVL5 mRNACTDPMID:17942748
Elovl5Rat17beta-estradiol increases expressionISOELOVL5 (Homo sapiens)6480464Estradiol results in increased expression of ELOVL5 mRNACTDPMID:16514628
Elovl5Rat17beta-estradiol increases expressionISOElovl5 (Mus musculus)6480464Estradiol results in increased expression of ELOVL5 mRNACTDPMID:39298647
Elovl5Rat17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of ELOVL5 mRNACTDPMID:32145629
Elovl5Rat17beta-estradiol multiple interactionsEXP 6480464[bisphenol A co-treated with Estradiol] results in decreased expression of ELOVL5 mRNACTDPMID:26496021
Elovl5Rat17beta-hydroxy-5alpha-androstan-3-one increases expressionISOELOVL5 (Homo sapiens)6480464Dihydrotestosterone results in increased expression of ELOVL5 mRNACTDPMID:29581250
Elovl5Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOElovl5 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ELOVL5 mRNACTDPMID:17942748
Elovl5Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOElovl5 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of ELOVL5 mRNACTDPMID:28238261
Elovl5Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOElovl5 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of ELOVL5 mRNACTDPMID:20702594 more ...
Elovl5Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of ELOVL5 mRNACTDPMID:16960034 more ...
Elovl5Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOElovl5 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of ELOVL5 mRNACTDPMID:16611356 more ...
Elovl5Rat2,3,7,8-Tetrachlorodibenzofuran affects expressionISOElovl5 (Mus musculus)64804642 more ...CTDPMID:20702594
Elovl5Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of ELOVL5 mRNACTDPMID:21346803
Elovl5Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of ELOVL5 mRNACTDPMID:21346803
Elovl5Rat2-bromohexadecanoic acid multiple interactionsISOELOVL5 (Homo sapiens)64804642-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of ELOVL5 protein]CTDPMID:38195004
Elovl5Rat2-hydroxypropanoic acid increases expressionISOELOVL5 (Homo sapiens)6480464Lactic Acid results in increased expression of ELOVL5 mRNACTDPMID:30851411

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Biological Process
1 to 20 of 39 rows

  
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Original Reference(s)
Elovl5Ratalpha-linolenic acid metabolic process involved_inISOElovl5 (Mus musculus)1624291MGI:3847980 PMID:18838740RGDPMID:18838740
Elovl5Ratalpha-linolenic acid metabolic process involved_inIEAUniProtKB:Q8BHI7 and ensembl:ENSMUSP000000349041600115GO_REF:0000107EnsemblGO_REF:0000107
Elovl5Ratfatty acid biosynthetic process involved_inIEAUniProtKB-KW:KW-02751600115GO_REF:0000043UniProtGO_REF:0000043
Elovl5Ratfatty acid biosynthetic process involved_inIEAUniProtKB:Q8BHI7 and ensembl:ENSMUSP000000349041600115GO_REF:0000107EnsemblGO_REF:0000107
Elovl5Ratfatty acid biosynthetic process involved_inISOElovl5 (Mus musculus)1624291MGI:3847980 PMID:18838740 and PMID:35933444RGDPMID:18838740 and PMID:35933444
Elovl5Ratfatty acid derivative biosynthetic process involved_inISOElovl5 (Mus musculus)1624291MGI:3847980 PMID:18838740RGDPMID:18838740
Elovl5Ratfatty acid derivative biosynthetic process involved_inIEAUniProtKB:Q8BHI7 and ensembl:ENSMUSP000000349041600115GO_REF:0000107EnsemblGO_REF:0000107
Elovl5Ratfatty acid elongation, monounsaturated fatty acid involved_inISSUniProtKB:Q9NYP71600115GO_REF:0000024UniProtGO_REF:0000024
Elovl5Ratfatty acid elongation, monounsaturated fatty acid involved_inIEAUniProtKB:Q9NYP7 and ensembl:ENSP000003066401600115GO_REF:0000107EnsemblGO_REF:0000107
Elovl5Ratfatty acid elongation, monounsaturated fatty acid involved_inIBAMGI:1195976 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Elovl5Ratfatty acid elongation, monounsaturated fatty acid involved_inISOELOVL5 (Homo sapiens)1624291 PMID:20427700RGDPMID:20427700
Elovl5Ratfatty acid elongation, monounsaturated fatty acid involved_inIEAUniRule:UR0002549181600115GO_REF:0000104UniProtGO_REF:0000104
Elovl5Ratfatty acid elongation, polyunsaturated fatty acid involved_inIEAUniRule:UR0002549181600115GO_REF:0000104UniProtGO_REF:0000104
Elovl5Ratfatty acid elongation, polyunsaturated fatty acid involved_inIEAUniProtKB:Q9NYP7 and ensembl:ENSP000003066401600115GO_REF:0000107EnsemblGO_REF:0000107
Elovl5Ratfatty acid elongation, polyunsaturated fatty acid involved_inIBAMGI:1858960 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Elovl5Ratfatty acid elongation, polyunsaturated fatty acid involved_inISOELOVL5 (Homo sapiens)1624291 PMID:20427700 and PMID:20937905RGDPMID:20427700 and PMID:20937905
Elovl5Ratfatty acid elongation, polyunsaturated fatty acid involved_inIDA 8554529PMID:12005057UniProt 
Elovl5Ratfatty acid elongation, saturated fatty acid involved_inIEAInterPro:IPR0336771600115GO_REF:0000002InterProGO_REF:0000002
Elovl5Ratfatty acid elongation, saturated fatty acid involved_inIBAFB:FBgn0260960 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Elovl5Ratfatty acid metabolic process involved_inIEAUniProtKB-KW:KW-02761600115GO_REF:0000043UniProtGO_REF:0000043
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Cellular Component
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Original Reference(s)
Elovl5Ratcell projection located_inIEAUniProtKB-KW:KW-09661600115GO_REF:0000043UniProtGO_REF:0000043
Elovl5Ratdendrite located_inIEAUniProtKB-SubCell:SL-02831600115GO_REF:0000044UniProtGO_REF:0000044
Elovl5Ratdendritic tree located_inISSUniProtKB:Q9NYP71600115GO_REF:0000024UniProtGO_REF:0000024
Elovl5Ratdendritic tree located_inIEAUniProtKB:Q9NYP7 and ensembl:ENSP000003066401600115GO_REF:0000107EnsemblGO_REF:0000107
Elovl5Ratdendritic tree located_inISOELOVL5 (Homo sapiens)1624291 PMID:25065913RGDPMID:25065913
Elovl5Ratendoplasmic reticulum located_inISOELOVL5 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Elovl5Ratendoplasmic reticulum located_inIEAUniProtKB:Q9NYP7 and ensembl:ENSP000003066401600115GO_REF:0000107EnsemblGO_REF:0000107
Elovl5Ratendoplasmic reticulum located_inIEAInterPro:IPR0336771600115GO_REF:0000002InterProGO_REF:0000002
Elovl5Ratendoplasmic reticulum located_inIEAUniProtKB-KW:KW-02561600115GO_REF:0000043UniProtGO_REF:0000043
Elovl5Ratendoplasmic reticulum located_inISOELOVL5 (Homo sapiens)1624291 PMID:20937905RGDPMID:20937905
Elovl5Ratendoplasmic reticulum membrane is_active_inIBAMGI:2156528 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Elovl5Ratendoplasmic reticulum membrane is_active_inIEAUniProtKB:Q8BHI7 and ensembl:ENSMUSP000000349041600115GO_REF:0000107EnsemblGO_REF:0000107
Elovl5Ratendoplasmic reticulum membrane located_inIEAUniRule:UR0002549181600115GO_REF:0000104UniProtGO_REF:0000104
Elovl5Ratendoplasmic reticulum membrane is_active_inISOElovl5 (Mus musculus)1624291MGI:3847980 PMID:18838740RGDPMID:18838740
Elovl5Ratendoplasmic reticulum membrane located_inIEAUniProtKB-SubCell:SL-00971600115GO_REF:0000044UniProtGO_REF:0000044
Elovl5Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Elovl5Ratmembrane located_inIEAUniRule:UR0002549181600115GO_REF:0000104UniProtGO_REF:0000104
Elovl5Ratmembrane located_inIEAInterPro:IPR0020761600115GO_REF:0000002InterProGO_REF:0000002
Elovl5Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Elovl5Ratneuronal cell body located_inISSUniProtKB:Q9NYP71600115GO_REF:0000024UniProtGO_REF:0000024
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Molecular Function
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Original Reference(s)
Elovl5Ratfatty acid elongase activity enablesISOELOVL5 (Homo sapiens)1624291 PMID:10970790 and PMID:20427700RGDPMID:10970790 and PMID:20427700
Elovl5Ratfatty acid elongase activity enablesIEAUniProtKB:Q9NYP7 and ensembl:ENSP000003066401600115GO_REF:0000107EnsemblGO_REF:0000107
Elovl5Ratfatty acid elongase activity enablesIEARHEA:327271600115GO_REF:0000116RHEAGO_REF:0000116
Elovl5Ratfatty acid elongase activity enablesIEAInterPro:IPR002076 and InterPro:IPR0336771600115GO_REF:0000002InterProGO_REF:0000002
Elovl5Ratfatty acid elongase activity enablesIEAUniProtKB:Q8BHI7 and ensembl:ENSMUSP000000349041600115GO_REF:0000107EnsemblGO_REF:0000107
Elovl5Ratfatty acid elongase activity enablesISOElovl5 (Mus musculus)1624291MGI:3847980 PMID:18838740RGDPMID:18838740
Elovl5Ratfatty acid elongase activity enablesIEAInterPro:IPR0020761600115GO_REF:0000002InterProGO_REF:0000002
Elovl5Ratfatty acid elongase activity enablesIBAFB:FBgn0034382 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Elovl5Ratfatty acid elongase activity enablesIEAEC:2.3.1.1991600115GO_REF:0000003UniProtGO_REF:0000003
Elovl5Ratfatty acid elongase activity enablesIDA 8554529PMID:12005057UniProt 
Elovl5Ratfatty acid elongase activity enablesIEAUniRule:UR0002549181600115GO_REF:0000104UniProtGO_REF:0000104
Elovl5Ratprotein binding enablesISOELOVL5 (Homo sapiens)1624291UniProtKB:A0AVG3 more ...RGDPMID:20937905 more ...
Elovl5Rattransferase activity enablesIEAUniProtKB-KW:KW-08081600115GO_REF:0000043UniProtGO_REF:0000043
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Imported Annotations - SMPDB

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Original Reference(s)
Elovl5Ratalpha-linolenic acid metabolic pathway  ISOELOVL5 (Homo sapiens)10402751 SMPDBSMP:00018
Elovl5Ratlinoleic acid metabolic pathway  ISOELOVL5 (Homo sapiens)10402751 SMPDBSMP:00018

Imported Annotations - KEGG (archival)

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Original Reference(s)
Elovl5Ratunsaturated fatty acid biosynthetic pathway  IEA 6907045 KEGGrno:01040

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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Identification and expression of a rat fatty acid elongase involved in the biosynthesis of C18 fatty acids. Inagaki K, etal., Biosci Biotechnol Biochem. 2002 Mar;66(3):613-21.
3. Cloning of a human cDNA encoding a novel enzyme involved in the elongation of long-chain polyunsaturated fatty acids. Leonard AE, etal., Biochem J 2000 Sep 15;350 Pt 3:765-70.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. (-)-Epigallocatechin-3-Gallate Ameliorates Atherosclerosis and Modulates Hepatic Lipid Metabolic Gene Expression in Apolipoprotein E Knockout Mice: Involvement of TTC39B. Wang W, etal., Front Pharmacol. 2018 Mar 9;9:195. doi: 10.3389/fphar.2018.00195. eCollection 2018.
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PMID:12371743   PMID:14636670   PMID:19946888   PMID:20228221   PMID:20427700   PMID:20937905   PMID:22216341   PMID:23749231   PMID:23873268   PMID:25046614   PMID:25065913  



Elovl5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8887,671,164 - 87,737,618 (+)NCBIGRCr8
mRatBN7.2878,790,846 - 78,857,307 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl878,790,846 - 78,857,284 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx884,316,763 - 84,342,848 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0882,593,410 - 82,619,495 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0880,416,122 - 80,442,207 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0885,220,941 - 85,287,449 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl885,259,982 - 85,285,983 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0884,786,562 - 84,853,064 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4882,922,551 - 82,948,348 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1882,941,604 - 82,967,402 (+)NCBI
Celera878,575,885 - 78,600,766 (+)NCBICelera
Cytogenetic Map8q31NCBI
ELOVL5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38653,267,404 - 53,348,950 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl653,267,398 - 53,349,179 (-)EnsemblGRCh38hg38GRCh38
GRCh37653,132,202 - 53,213,748 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36653,240,155 - 53,321,901 (-)NCBINCBI36Build 36hg18NCBI36
Build 34653,240,154 - 53,321,901NCBI
Celera654,794,435 - 54,876,099 (-)NCBICelera
Cytogenetic Map6p12.1NCBI
HuRef652,964,031 - 53,045,647 (-)NCBIHuRef
CHM1_1653,134,061 - 53,215,737 (-)NCBICHM1_1
T2T-CHM13v2.0653,107,162 - 53,188,820 (-)NCBIT2T-CHM13v2.0
Elovl5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39977,824,647 - 77,891,801 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl977,824,646 - 77,891,801 (+)EnsemblGRCm39 Ensembl
GRCm38977,917,365 - 77,984,519 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl977,917,364 - 77,984,519 (+)EnsemblGRCm38mm10GRCm38
MGSCv37977,765,172 - 77,832,326 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36977,703,052 - 77,770,197 (+)NCBIMGSCv36mm8
Celera975,090,915 - 75,160,354 (+)NCBICelera
Cytogenetic Map9E1NCBI
cM Map943.36NCBI
Elovl5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554112,747,232 - 2,812,544 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554112,747,232 - 2,812,544 (+)NCBIChiLan1.0ChiLan1.0
ELOVL5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2567,738,260 - 67,818,363 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1663,614,887 - 63,694,873 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0652,822,038 - 52,902,122 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1654,457,569 - 54,537,648 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl654,451,887 - 54,485,878 (-)Ensemblpanpan1.1panPan2
ELOVL5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11220,732,641 - 20,807,748 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1220,734,282 - 20,807,739 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1220,629,994 - 20,705,080 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01221,233,696 - 21,308,436 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1221,233,725 - 21,308,442 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11220,735,219 - 20,810,057 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01220,843,290 - 20,918,321 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01220,980,845 - 21,055,936 (-)NCBIUU_Cfam_GSD_1.0
Elovl5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494656,341,932 - 56,423,606 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364767,536,635 - 7,618,271 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELOVL5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl746,860,770 - 46,932,926 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1746,860,768 - 46,932,945 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ELOVL5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11719,227,209 - 19,305,789 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1719,277,593 - 19,307,625 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604453,118,840 - 53,197,198 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Elovl5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624850522,018 - 597,469 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624850523,059 - 598,135 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Elovl5
273 total Variants

Predicted Target Of
Summary Value
Count of predictions:50
Count of miRNA genes:46
Interacting mature miRNAs:50
Transcripts:ENSRNOT00000010409
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 57 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85009524982460899Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat

1 to 10 of 57 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000010409   ⟹   ENSRNOP00000010409
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl878,790,846 - 78,857,284 (+)Ensembl
Rnor_6.0 Ensembl885,259,982 - 85,285,983 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110892   ⟹   ENSRNOP00000083526
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl878,832,699 - 78,857,284 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115564   ⟹   ENSRNOP00000092513
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl878,808,540 - 78,857,284 (+)Ensembl
RefSeq Acc Id: NM_134382   ⟹   NP_599209
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8887,671,164 - 87,737,618 (+)NCBI
mRatBN7.2878,790,846 - 78,857,307 (+)NCBI
Rnor_6.0885,259,988 - 85,285,785 (+)NCBI
Rnor_5.0884,786,562 - 84,853,064 (+)NCBI
RGSC_v3.4882,922,551 - 82,948,348 (+)RGD
Celera878,575,885 - 78,600,766 (+)RGD
Sequence:
RefSeq Acc Id: XM_063264837   ⟹   XP_063120907
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8887,683,961 - 87,737,618 (+)NCBI
Protein RefSeqs NP_599209 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120907 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ADP36858 (Get FASTA)   NCBI Sequence Viewer  
  BAB69887 (Get FASTA)   NCBI Sequence Viewer  
  EDL77758 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000010409
  ENSRNOP00000010409.3
GenBank Protein Q920L7 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_599209   ⟸   NM_134382
- UniProtKB: G9BD46 (UniProtKB/Swiss-Prot),   Q920L7 (UniProtKB/Swiss-Prot),   A0A8I6AI17 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000010409   ⟸   ENSRNOT00000010409
Ensembl Acc Id: ENSRNOP00000083526   ⟸   ENSRNOT00000110892
Ensembl Acc Id: ENSRNOP00000092513   ⟸   ENSRNOT00000115564
RefSeq Acc Id: XP_063120907   ⟸   XM_063264837
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AI17 (UniProtKB/TrEMBL)

Name Modeler Protein Id AA Range Protein Structure
AF-Q920L7-F1-model_v2 AlphaFold Q920L7 1-299 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 20 of 20 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-29779 BioCyc
Ensembl Genes ENSRNOG00000006331 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000010409 ENTREZGENE
  ENSRNOT00000010409.5 UniProtKB/Swiss-Prot
InterPro ELO_fam UniProtKB/Swiss-Prot
  ELOVL5 UniProtKB/Swiss-Prot
KEGG Report rno:171400 UniProtKB/Swiss-Prot
NCBI Gene 171400 ENTREZGENE
PANTHER PTHR11157 UniProtKB/Swiss-Prot
  PTHR11157:SF18 UniProtKB/Swiss-Prot
Pfam ELO UniProtKB/Swiss-Prot
PhenoGen Elovl5 PhenoGen
RatGTEx ENSRNOG00000006331 RatGTEx
UniProt A0A8I5ZXD3_RAT UniProtKB/TrEMBL
  A0A8I6AI17 ENTREZGENE, UniProtKB/TrEMBL
  A6I1G9_RAT UniProtKB/TrEMBL
  ELOV5_RAT UniProtKB/Swiss-Prot
  G9BD46 ENTREZGENE
  Q920L7 ENTREZGENE
UniProt Secondary G9BD46 UniProtKB/Swiss-Prot
1 to 20 of 20 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-01-25 Elovl5  ELOVL fatty acid elongase 5  Elovl5  ELOVL family member 5, elongation of long chain fatty acids (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Elovl5  ELOVL family member 5, elongation of long chain fatty acids (yeast)  rELO1  fatty acid elongase 1  Symbol and Name updated 1299863 APPROVED
2002-08-07 rELO1  fatty acid elongase 1      Symbol and Name status set to provisional 70820 PROVISIONAL