ELOVL5 (ELOVL fatty acid elongase 5) - Rat Genome Database

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Gene: ELOVL5 (ELOVL fatty acid elongase 5) Canis lupus familiaris
Analyze
Symbol: ELOVL5
Name: ELOVL fatty acid elongase 5
RGD ID: 12072958
Description: ENCODES a protein that exhibits fatty acid elongase activity (inferred); transferase activity (inferred); INVOLVED IN fatty acid biosynthetic process (inferred); fatty acid elongation, monounsaturated fatty acid (inferred); fatty acid elongation, polyunsaturated fatty acid (inferred); PARTICIPATES IN alpha-linolenic acid metabolic pathway; linoleic acid metabolic pathway; ASSOCIATED WITH atherosclerosis (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN cell projection (inferred); dendrite (inferred); dendritic tree (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: elongation of very long chain fatty acids protein 5; ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11220,732,641 - 20,807,748 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1220,734,282 - 20,807,739 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1220,629,994 - 20,705,080 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01221,233,696 - 21,308,436 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1221,233,725 - 21,308,442 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11220,735,219 - 20,810,057 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01220,843,290 - 20,918,321 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01220,980,845 - 21,055,936 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ELOVL5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11220,732,641 - 20,807,748 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1220,734,282 - 20,807,739 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1220,629,994 - 20,705,080 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01221,233,696 - 21,308,436 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1221,233,725 - 21,308,442 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11220,735,219 - 20,810,057 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01220,843,290 - 20,918,321 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01220,980,845 - 21,055,936 (-)NCBIUU_Cfam_GSD_1.0
ELOVL5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38653,267,404 - 53,348,950 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl653,267,398 - 53,349,179 (-)EnsemblGRCh38hg38GRCh38
GRCh37653,132,202 - 53,213,748 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36653,240,155 - 53,321,901 (-)NCBINCBI36Build 36hg18NCBI36
Build 34653,240,154 - 53,321,901NCBI
Celera654,794,435 - 54,876,099 (-)NCBICelera
Cytogenetic Map6p12.1NCBI
HuRef652,964,031 - 53,045,647 (-)NCBIHuRef
CHM1_1653,134,061 - 53,215,737 (-)NCBICHM1_1
T2T-CHM13v2.0653,107,162 - 53,188,820 (-)NCBIT2T-CHM13v2.0
Elovl5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39977,824,647 - 77,891,801 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl977,824,646 - 77,891,801 (+)EnsemblGRCm39 Ensembl
GRCm38977,917,365 - 77,984,519 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl977,917,364 - 77,984,519 (+)EnsemblGRCm38mm10GRCm38
MGSCv37977,765,172 - 77,832,326 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36977,703,052 - 77,770,197 (+)NCBIMGSCv36mm8
Celera975,090,915 - 75,160,354 (+)NCBICelera
Cytogenetic Map9E1NCBI
cM Map943.36NCBI
Elovl5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8887,671,164 - 87,737,618 (+)NCBIGRCr8
mRatBN7.2878,790,846 - 78,857,307 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl878,790,846 - 78,857,284 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx884,316,763 - 84,342,848 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0882,593,410 - 82,619,495 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0880,416,122 - 80,442,207 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0885,220,941 - 85,287,449 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl885,259,982 - 85,285,983 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0884,786,562 - 84,853,064 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4882,922,551 - 82,948,348 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1882,941,604 - 82,967,402 (+)NCBI
Celera878,575,885 - 78,600,766 (+)NCBICelera
Cytogenetic Map8q31NCBI
Elovl5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554112,747,232 - 2,812,544 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554112,747,232 - 2,812,544 (+)NCBIChiLan1.0ChiLan1.0
ELOVL5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2567,738,260 - 67,818,363 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1663,614,887 - 63,694,873 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0652,822,038 - 52,902,122 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1654,457,569 - 54,537,648 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl654,451,887 - 54,485,878 (-)Ensemblpanpan1.1panPan2
Elovl5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494656,341,932 - 56,423,606 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364767,536,635 - 7,618,271 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELOVL5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl746,860,770 - 46,932,926 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1746,860,768 - 46,932,945 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ELOVL5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11719,227,209 - 19,305,789 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1719,277,593 - 19,307,625 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604453,118,840 - 53,197,198 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Elovl5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624850522,018 - 597,469 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624850523,059 - 598,135 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ELOVL5
596 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 22 6 6 6 6 12 8 10 6
Low 5 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_014118055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022426157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038492055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038492056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038492057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038554321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038554322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038554323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038618183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038618184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038618186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038683772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038683773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038683774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_847869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000003575   ⟹   ENSCAFP00000003311
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1220,734,282 - 20,807,739 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000044079   ⟹   ENSCAFP00000036331
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1220,734,282 - 20,807,739 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845017901   ⟹   ENSCAFP00845013945
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1221,233,725 - 21,308,442 (-)Ensembl
RefSeq Acc Id: XM_014118055   ⟹   XP_013973530
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11220,732,641 - 20,760,209 (-)NCBI
Dog10K_Boxer_Tasha1220,629,994 - 20,657,571 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022426157   ⟹   XP_022281865
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11220,732,641 - 20,757,100 (-)NCBI
Dog10K_Boxer_Tasha1220,629,994 - 20,654,462 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038492055   ⟹   XP_038347983
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11220,735,219 - 20,810,057 (-)NCBI
RefSeq Acc Id: XM_038492056   ⟹   XP_038347984
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11220,735,219 - 20,759,662 (-)NCBI
RefSeq Acc Id: XM_038492057   ⟹   XP_038347985
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11220,735,219 - 20,762,771 (-)NCBI
RefSeq Acc Id: XM_038554321   ⟹   XP_038410249
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01220,980,845 - 21,055,936 (-)NCBI
RefSeq Acc Id: XM_038554322   ⟹   XP_038410250
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01220,980,845 - 21,005,311 (-)NCBI
RefSeq Acc Id: XM_038554323   ⟹   XP_038410251
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01220,980,845 - 21,008,422 (-)NCBI
RefSeq Acc Id: XM_038618183   ⟹   XP_038474111
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01220,843,290 - 20,918,321 (-)NCBI
RefSeq Acc Id: XM_038618184   ⟹   XP_038474112
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01220,843,290 - 20,867,903 (-)NCBI
RefSeq Acc Id: XM_038618186   ⟹   XP_038474114
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01220,843,290 - 20,871,014 (-)NCBI
RefSeq Acc Id: XM_038683772   ⟹   XP_038539700
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01221,233,696 - 21,308,436 (-)NCBI
RefSeq Acc Id: XM_038683773   ⟹   XP_038539701
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01221,233,696 - 21,258,002 (-)NCBI
RefSeq Acc Id: XM_038683774   ⟹   XP_038539702
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01221,233,696 - 21,261,112 (-)NCBI
RefSeq Acc Id: XM_847869   ⟹   XP_852962
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11220,732,641 - 20,807,748 (-)NCBI
Dog10K_Boxer_Tasha1220,629,994 - 20,705,080 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_852962   ⟸   XM_847869
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NPH6 (UniProtKB/TrEMBL),   A0A8C0KKT2 (UniProtKB/TrEMBL),   A0A8I3RXL7 (UniProtKB/TrEMBL),   A0A8P0S845 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013973530   ⟸   XM_014118055
- Peptide Label: isoform X3
- UniProtKB: A0A8C0RM88 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022281865   ⟸   XM_022426157
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCAFP00000036331   ⟸   ENSCAFT00000044079
RefSeq Acc Id: ENSCAFP00000003311   ⟸   ENSCAFT00000003575
RefSeq Acc Id: XP_038347983   ⟸   XM_038492055
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038347985   ⟸   XM_038492057
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038347984   ⟸   XM_038492056
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038474111   ⟸   XM_038618183
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038474114   ⟸   XM_038618186
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038474112   ⟸   XM_038618184
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038539700   ⟸   XM_038683772
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NPH6 (UniProtKB/TrEMBL),   A0A8C0KKT2 (UniProtKB/TrEMBL),   A0A8I3RXL7 (UniProtKB/TrEMBL),   A0A8P0S845 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038539702   ⟸   XM_038683774
- Peptide Label: isoform X3
- UniProtKB: A0A8C0RM88 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038539701   ⟸   XM_038683773
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038410249   ⟸   XM_038554321
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KKT2 (UniProtKB/TrEMBL),   A0A8C0NPH6 (UniProtKB/TrEMBL),   A0A8I3RXL7 (UniProtKB/TrEMBL),   A0A8P0S845 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038410251   ⟸   XM_038554323
- Peptide Label: isoform X3
- UniProtKB: A0A8C0RM88 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038410250   ⟸   XM_038554322
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCAFP00845013945   ⟸   ENSCAFT00845017901


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000002276 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030017213 UniProtKB/TrEMBL
  ENSCAFG00040006691 UniProtKB/TrEMBL
  ENSCAFG00845010176 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000003575.6 UniProtKB/TrEMBL
  ENSCAFT00030031767.1 UniProtKB/TrEMBL
  ENSCAFT00030031809.1 UniProtKB/TrEMBL
  ENSCAFT00030031865.1 UniProtKB/TrEMBL
  ENSCAFT00040012446.1 UniProtKB/TrEMBL
  ENSCAFT00040012462.1 UniProtKB/TrEMBL
  ENSCAFT00845017901 ENTREZGENE
  ENSCAFT00845017901.1 UniProtKB/TrEMBL
InterPro ELO_fam UniProtKB/TrEMBL
  ELOVL5 UniProtKB/TrEMBL
KEGG Report cfa:610377 UniProtKB/TrEMBL
NCBI Gene ELOVL5 ENTREZGENE
PANTHER PTHR11157 UniProtKB/TrEMBL
  PTHR11157:SF18 UniProtKB/TrEMBL
Pfam ELO UniProtKB/TrEMBL
UniProt A0A8C0KKT2 ENTREZGENE
  A0A8C0NLT7_CANLF UniProtKB/TrEMBL
  A0A8C0NPH6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0RM88 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RXL7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0S845 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:40323 ENTREZGENE