Gene: Acat1 (acetyl-CoA acetyltransferase 1) Rattus norvegicus
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Symbol: Acat1
Name: acetyl-CoA acetyltransferase 1
Description: ENCODES a protein that exhibits acetyl-CoA C-acetyltransferase activity; coenzyme binding; enzyme binding; INVOLVED IN adipose tissue development; brain development; liver development; PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyacyl-CoA dehydrogenase deficiency pathway; ASSOCIATED WITH end stage renal failure; nephrotic syndrome; arteriosclerosis (ortholog); FOUND IN mitochondrial matrix; mitochondrion; INTERACTS WITH (+)-alpha-tocopherol; 1,2,4-trimethylbenzene; 1,3-dinitrobenzene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: acetoacetyl-CoA thiolase; Acetyl-Co A acetyltransferase 1 mitochondrial; Acetyl-Co A acetyltransferase 1, mitochondrial; acetyl-CoA acetyltransferase, mitochondrial; acetyl-Coenzyme A acetyltransferase 1; RATACAL
Orthologs:
Homo sapiens (human) : ACAT1 (acetyl-CoA acetyltransferase 1)  HGNC  Alliance
Mus musculus (house mouse) : Acat1 (acetyl-Coenzyme A acetyltransferase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acat1 (acetyl-CoA acetyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ACAT1 (acetyl-CoA acetyltransferase 1)
Canis lupus familiaris (dog) : ACAT1 (acetyl-CoA acetyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acat1 (acetyl-CoA acetyltransferase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0858,166,990 - 58,195,884 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0856,749,861 - 56,778,336 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4857,044,478 - 57,072,970 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1857,063,521 - 57,092,024 (-)NCBI
Celera853,470,530 - 53,499,505 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Acat1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2016
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-05-29
Status: ACTIVE