Acat1 (acetyl-CoA acetyltransferase 1) - Rat Genome Database

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Gene: Acat1 (acetyl-CoA acetyltransferase 1) Ictidomys tridecemlineatus
Analyze
Symbol: Acat1
Name: acetyl-CoA acetyltransferase 1
RGD ID: 12575166
Description: ENCODES a protein that exhibits acetyl-CoA C-acetyltransferase activity (ortholog); C-acetyltransferase activity (ortholog); coenzyme A binding (ortholog); INVOLVED IN acetyl-CoA biosynthetic process (ortholog); acetyl-CoA catabolic process (ortholog); adipose tissue development (ortholog); PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyacyl-CoA dehydrogenase deficiency pathway; ASSOCIATED WITH arteriosclerosis (ortholog); ataxia telangiectasia (ortholog); beta-ketothiolase deficiency (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog); peroxisome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: acetyl-CoA acetyltransferase, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494790,910,486 - 90,941,886 (+)NCBI
SpeTri2.0NW_004936551594,647 - 626,016 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
2-aminoadipic 2-oxoadipic aciduria pathway  (ISO)
3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway  (ISO)
3-hydroxyacyl-CoA dehydrogenase deficiency pathway  (ISO)
3-hydroxyisobutyric aciduria pathway  (ISO)
3-methylcrotonyl CoA carboxylase 1 deficiency pathway  (ISO)
3-methylglutaconic aciduria type 1 pathway  (ISO)
3-methylglutaconic aciduria type 3 pathway  (ISO)
butanoate metabolic pathway  (ISO)
carnitine palmitoyltransferase I deficiency pathway  (ISO)
ethylmalonic encephalopathy pathway  (ISO)
fatty acid beta degradation pathway  (ISO)
fatty acid metabolic pathway  (ISO)
glutaric aciduria type I pathway  (ISO)
hyperlysinemia pathway  (ISO)
isobutyryl-CoA dehydrogenase deficiency pathway  (ISO)
isovaleric acidemia pathway  (ISO)
ketone bodies metabolic pathway  (ISO)
Leigh disease pathway  (ISO)
lysine degradation pathway  (ISO)
malonic aciduria pathway  (ISO)
maple syrup urine disease pathway  (ISO)
medium chain acyl-CoA dehydrogenase deficiency pathway  (ISO)
methylmalonate semialdehyde dehydrogenase deficiency pathway  (ISO)
methylmalonic acidemia pathway  (ISO)
methylmalonic aciduria, cobalamin-related pathway  (ISO)
primary hyperoxaluria type 2 pathway  (ISO)
propanoate metabolic pathway  (ISO)
propionic acidemia pathway  (ISO)
pyruvate decarboxylase deficiency pathway  (ISO)
pyruvate dehydrogenase E1 deficiency pathway  (ISO)
pyruvate kinase deficiency of red cells pathway  (ISO)
pyruvate metabolic pathway  (ISO)
saccharopinuria pathway  (ISO)
short-chain acyl-CoA dehydrogenase deficiency pathway  (ISO)
succinyl-CoA:3-oxoacid transferase deficiency pathway  (ISO)
trifunctional protein deficiency pathway  (ISO)
valine, leucine and isoleucine degradation pathway  (ISO)
very long-chain acyl-CoA dehydrogenase deficiency pathway  (ISO)

References

Genomics

Comparative Map Data
Acat1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494790,910,486 - 90,941,886 (+)NCBI
SpeTri2.0NW_004936551594,647 - 626,016 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACAT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl11108,116,695 - 108,147,603 (+)EnsemblGRCh38hg38GRCh38
GRCh3811108,116,705 - 108,148,822 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711107,987,432 - 108,018,330 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611107,497,468 - 107,523,485 (+)NCBINCBI36hg18NCBI36
Build 3411107,497,467 - 107,523,485NCBI
Celera11105,147,145 - 105,173,805 (+)NCBI
Cytogenetic Map11q22.3NCBI
HuRef11103,917,783 - 103,944,520 (+)NCBIHuRef
CHM1_111107,875,420 - 107,902,046 (+)NCBICHM1_1
Acat1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39953,491,822 - 53,521,650 (-)NCBIGRCm39mm39
GRCm39 Ensembl953,491,822 - 53,521,682 (-)Ensembl
GRCm38953,580,522 - 53,610,350 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl953,580,522 - 53,610,382 (-)EnsemblGRCm38mm10GRCm38
MGSCv37953,388,627 - 53,418,455 (-)NCBIGRCm37mm9NCBIm37
MGSCv36953,342,917 - 53,372,745 (-)NCBImm8
Celera950,840,318 - 50,870,157 (-)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map929.12NCBI
Acat1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2853,979,813 - 54,008,861 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl853,979,813 - 54,008,855 (-)Ensembl
Rnor_6.0858,166,990 - 58,195,884 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl858,166,990 - 58,195,884 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0856,749,861 - 56,778,336 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4857,044,478 - 57,072,970 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1857,063,521 - 57,092,024 (-)NCBI
Celera853,470,530 - 53,499,505 (-)NCBICelera
Cytogenetic Map8q24NCBI
Acat1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541210,349,593 - 10,369,806 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541210,350,088 - 10,369,806 (+)NCBIChiLan1.0ChiLan1.0
ACAT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.111106,483,563 - 106,509,793 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11106,483,563 - 106,509,787 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v011103,008,564 - 103,034,697 (+)NCBIMhudiblu_PPA_v0panPan3
ACAT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1524,361,301 - 24,379,807 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl524,361,301 - 24,379,812 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha524,286,784 - 24,306,232 (-)NCBI
ROS_Cfam_1.0524,389,926 - 24,409,658 (-)NCBI
UMICH_Zoey_3.1524,437,216 - 24,456,918 (-)NCBI
UNSW_CanFamBas_1.0524,338,692 - 24,358,333 (-)NCBI
UU_Cfam_GSD_1.0524,396,960 - 24,416,675 (-)NCBI
ACAT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl936,525,261 - 36,545,633 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1936,525,266 - 36,545,634 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2940,601,654 - 40,622,145 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ACAT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1199,552,760 - 99,580,079 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl199,552,838 - 99,579,914 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604326,378,291 - 26,404,565 (-)NCBIVero_WHO_p1.0
Acat1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247842,833,344 - 2,879,043 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005329071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005329071   ⟹   XP_005329128
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494790,910,486 - 90,941,886 (+)NCBI
SpeTri2.0NW_004936551594,647 - 626,016 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005329128 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3286479 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005329128   ⟸   XM_005329071
- UniProtKB: I3M435 (UniProtKB/TrEMBL)
- Sequence:


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000004363 ENTREZGENE
Ensembl Protein ENSSTOP00000003916 ENTREZGENE
NCBI Gene Acat1 ENTREZGENE
UniProt I3M435 ENTREZGENE