ACAT1 (acetyl-CoA acetyltransferase 1)

Gene: ACAT1 (acetyl-CoA acetyltransferase 1) Canis lupus familiaris

Analyze

Symbol:

ACAT1

Name:

acetyl-CoA acetyltransferase 1

RGD ID:

12261416

Description:

ENCODES a protein that exhibits acetyl-CoA C-acetyltransferase activity (ortholog); coenzyme A binding (ortholog); enzyme binding (ortholog); INVOLVED IN adipose tissue development (ortholog); liver development (ortholog); metanephric proximal convoluted tubule development (ortholog); PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyacyl-CoA dehydrogenase deficiency pathway; ASSOCIATED WITH arteriosclerosis (ortholog); ataxia telangiectasia (ortholog); beta-ketothiolase deficiency (ortholog); FOUND IN endoplasmic reticulum (ortholog); mitochondrial matrix (ortholog); peroxisome (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

acetyl-CoA acetyltransferase, mitochondrial; acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	24,361,301 - 24,379,807 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	24,361,301 - 24,379,812 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	24,286,784 - 24,306,232 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	24,389,926 - 24,409,658 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	24,389,926 - 24,409,643 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	24,437,216 - 24,456,918 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	24,338,692 - 24,358,333 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	24,396,960 - 24,416,675 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

arteriosclerosis (ISO)

ataxia telangiectasia (ISO)

beta-ketothiolase deficiency (ISO)

carbohydrate metabolic disorder (ISO)

Chromosome 11, Partial Trisomy 11q (ISO)

end stage renal disease (ISO)

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

intellectual disability (ISO)

nephrotic syndrome (ISO)

steatotic liver disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

acetyl-CoA biosynthetic process (IEA)

acetyl-CoA catabolic process (IEA)

adipose tissue development (ISO)

coenzyme A biosynthetic process (IEA)

coenzyme A metabolic process (IEA)

fatty acid beta-oxidation (IEA)

isoleucine catabolic process (IEA)

ketone body catabolic process (IEA)

liver development (ISO)

metanephric proximal convoluted tubule development (ISO)

propionyl-CoA biosynthetic process (IEA)

response to hormone (ISO)

response to organic cyclic compound (ISO)

response to starvation (ISO)

Cellular Component

endoplasmic reticulum (IEA,ISO)

mitochondrial matrix (ISO)

mitochondrion (IEA)

peroxisome (ISO)

Molecular Function

acetyl-CoA C-acetyltransferase activity (IEA,ISO)

acetyl-CoA C-acyltransferase activity (IEA)

acyltransferase activity (IEA)

acyltransferase activity, transferring groups other than amino-acyl groups (IEA)

C-acetyltransferase activity (IEA)

cholesterol O-acyltransferase activity (IEA)

coenzyme A binding (ISO)

enzyme binding (ISO)

identical protein binding (ISO)

metal ion binding (IEA)

potassium ion binding (IEA)

transferase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

2-aminoadipic 2-oxoadipic aciduria pathway (ISO)

3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway (ISO)

3-hydroxyacyl-CoA dehydrogenase deficiency pathway (ISO)

3-hydroxyisobutyric aciduria pathway (ISO)

3-methylcrotonyl CoA carboxylase 1 deficiency pathway (ISO)

3-methylglutaconic aciduria type 1 pathway (ISO)

3-methylglutaconic aciduria type 3 pathway (ISO)

butanoate metabolic pathway (ISO)

carnitine palmitoyltransferase I deficiency pathway (ISO)

ethylmalonic encephalopathy pathway (ISO)

fatty acid beta degradation pathway (ISO)

fatty acid metabolic pathway (ISO)

glutaric aciduria type I pathway (ISO)

hyperlysinemia pathway (ISO)

isobutyryl-CoA dehydrogenase deficiency pathway (ISO)

isovaleric acidemia pathway (ISO)

ketone bodies metabolic pathway (ISO)

Leigh disease pathway (ISO)

lysine degradation pathway (ISO)

malonic aciduria pathway (ISO)

maple syrup urine disease pathway (ISO)

medium chain acyl-CoA dehydrogenase deficiency pathway (ISO)

methylmalonate semialdehyde dehydrogenase deficiency pathway (ISO)

methylmalonic acidemia pathway (ISO)

methylmalonic aciduria, cobalamin-related pathway (ISO)

primary hyperoxaluria type 2 pathway (ISO)

propanoate metabolic pathway (ISO)

propionic acidemia pathway (ISO)

pyruvate decarboxylase deficiency pathway (ISO)

pyruvate dehydrogenase E1 deficiency pathway (ISO)

pyruvate kinase deficiency of red cells pathway (ISO)

pyruvate metabolic pathway (ISO)

saccharopinuria pathway (ISO)

short-chain acyl-CoA dehydrogenase deficiency pathway (ISO)

succinyl-CoA:3-oxoacid transferase deficiency pathway (ISO)

trifunctional protein deficiency pathway (ISO)

valine, leucine and isoleucine degradation pathway (ISO)

very long-chain acyl-CoA dehydrogenase deficiency pathway (ISO)

References

Additional References at PubMed

PMID:30032202	PMID:37756605

Genomics

Comparative Map Data

ACAT1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	24,361,301 - 24,379,807 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	24,361,301 - 24,379,812 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	24,286,784 - 24,306,232 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	24,389,926 - 24,409,658 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	24,389,926 - 24,409,643 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	24,437,216 - 24,456,918 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	24,338,692 - 24,358,333 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	24,396,960 - 24,416,675 (-)	NCBI		UU_Cfam_GSD_1.0

ACAT1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	108,116,705 - 108,147,603 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	108,116,695 - 108,147,603 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	107,987,432 - 108,018,330 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	107,497,468 - 107,523,485 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	107,497,467 - 107,523,485	NCBI
Celera	11	105,147,145 - 105,173,805 (+)	NCBI		Celera
Cytogenetic Map	11	q22.3	NCBI
HuRef	11	103,917,783 - 103,944,520 (+)	NCBI		HuRef
CHM1_1	11	107,875,420 - 107,902,046 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	108,124,245 - 108,155,151 (+)	NCBI		T2T-CHM13v2.0

Acat1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	53,491,822 - 53,521,650 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	53,491,822 - 53,521,682 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	53,580,522 - 53,610,350 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	53,580,522 - 53,610,382 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	53,388,627 - 53,418,455 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	53,342,917 - 53,372,745 (-)	NCBI		MGSCv36	mm8
Celera	9	50,840,318 - 50,870,157 (-)	NCBI		Celera
Cytogenetic Map	9	A5.3	NCBI
cM Map	9	29.12	NCBI

Acat1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	62,876,003 - 62,905,080 (-)	NCBI		GRCr8
mRatBN7.2	8	53,979,813 - 54,008,861 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	53,979,813 - 54,008,855 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	59,505,211 - 59,534,213 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	57,784,239 - 57,813,235 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	55,648,477 - 55,677,476 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	58,166,990 - 58,195,884 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	58,166,990 - 58,195,884 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	56,749,861 - 56,778,336 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	57,044,478 - 57,072,970 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	57,063,521 - 57,092,024 (-)	NCBI
Celera	8	53,470,530 - 53,499,505 (-)	NCBI		Celera
Cytogenetic Map	8	q24	NCBI

Acat1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	10,349,593 - 10,369,806 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955412	10,350,088 - 10,369,806 (+)	NCBI	ChiLan1.0	ChiLan1.0

ACAT1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	108,866,381 - 108,892,867 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	109,959,287 - 109,985,798 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	103,008,564 - 103,034,697 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	106,483,563 - 106,509,793 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	106,483,563 - 106,509,787 (+)	Ensembl	panpan1.1		panPan2

Acat1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	90,910,486 - 90,941,886 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936551	591,695 - 626,056 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936551	594,647 - 626,016 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ACAT1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	36,525,261 - 36,545,633 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	36,525,266 - 36,545,634 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	40,601,654 - 40,622,145 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ACAT1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	99,552,760 - 99,580,079 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	99,552,838 - 99,579,914 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	26,378,291 - 26,404,565 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Acat1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624784	2,833,344 - 2,879,043 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in ACAT1
224 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	5	5	22	6	6	6	6	6	12	8	10	6
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005619828	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038475151	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038475153	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038475154	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038511673	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038511682	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038536283	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038536284	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038536285	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038600482	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038600483	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038600484	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038665010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038665011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038665012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_546539	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000371	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000023145 ⟹ ENSCAFP00000021489

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	5	24,361,301 - 24,379,812 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000047270 ⟹ ENSCAFP00000035863

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	5	24,361,301 - 24,379,812 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845006376 ⟹ ENSCAFP00845005065

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	5	24,389,926 - 24,409,638 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845006382 ⟹ ENSCAFP00845005068

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	5	24,389,926 - 24,409,610 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845006396 ⟹ ENSCAFP00845005080

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	5	24,389,928 - 24,409,643 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845006403 ⟹ ENSCAFP00845005087

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	5	24,389,928 - 24,409,643 (-)	Ensembl

RefSeq Acc Id:

XM_038475151 ⟹ XP_038331079

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	5	24,437,216 - 24,456,319 (-)	NCBI

RefSeq Acc Id:

XM_038475153 ⟹ XP_038331081

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	5	24,437,216 - 24,456,918 (-)	NCBI

RefSeq Acc Id:

XM_038475154 ⟹ XP_038331082

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	5	24,437,216 - 24,456,580 (-)	NCBI

RefSeq Acc Id:

XM_038511673 ⟹ XP_038367601

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	5	24,286,784 - 24,306,232 (-)	NCBI

RefSeq Acc Id:

XM_038511682 ⟹ XP_038367610

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	5	24,286,784 - 24,305,894 (-)	NCBI

RefSeq Acc Id:

XM_038536283 ⟹ XP_038392211

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	5	24,396,960 - 24,416,076 (-)	NCBI

RefSeq Acc Id:

XM_038536284 ⟹ XP_038392212

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	5	24,396,960 - 24,416,675 (-)	NCBI

RefSeq Acc Id:

XM_038536285 ⟹ XP_038392213

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	5	24,396,960 - 24,416,337 (-)	NCBI

RefSeq Acc Id:

XM_038600482 ⟹ XP_038456410

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	5	24,338,692 - 24,357,734 (-)	NCBI

RefSeq Acc Id:

XM_038600483 ⟹ XP_038456411

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	5	24,338,692 - 24,358,333 (-)	NCBI

RefSeq Acc Id:

XM_038600484 ⟹ XP_038456412

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	5	24,338,692 - 24,357,995 (-)	NCBI

RefSeq Acc Id:

XM_038665010 ⟹ XP_038520938

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	5	24,389,926 - 24,409,059 (-)	NCBI

RefSeq Acc Id:

XM_038665011 ⟹ XP_038520939

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	5	24,389,926 - 24,409,658 (-)	NCBI

RefSeq Acc Id:

XM_038665012 ⟹ XP_038520940

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	5	24,389,926 - 24,409,320 (-)	NCBI

RefSeq Acc Id:

XM_546539 ⟹ XP_546539

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	5	24,361,301 - 24,379,807 (-)	NCBI
Dog10K_Boxer_Tasha	5	24,286,784 - 24,305,633 (-)	NCBI

Sequence:

show sequence

CCCCTCGCCCTTCTCGTCCTGTGTTTAGGGAACCGGGTGCGAGGGCCTTGAGAAGGGCAGTGTC
AAAGCATGGGAACCTGCATCTTGGATTTACCACCTGGCAAAACCTCGGGAGTAGTAGAGAACGC
CAGGGCGCGGCTGGTGAGGCGAGTTTGCCAGGCAGTCAGATACGTGGAGCGAAGTTACGTGTCA
AAACCCACTTTGAATGAGGTGGTCATAGTAAGTGCTGCAAGAACACCCATTGGATCCTTTTTGG
GCAGCCTTTCCTCCCTGCCGGCCACTAAACTTGGTTCCATTGCAATTCAGGGAGTCATTGAAAA
GGCAGGGATTCCAAAAGAAGAAGTGAAGGAAGCCTACATGGGGAATGTCCTACAAGGAGGCGAG
GGACAGGCCCCAACGAGGCAAGCGGCGCTGGGCGCAGGCTTACCTATTTCTACCCCGTGCACCA
CTGTAAACAAAGTCTGTGCCTCCGGAATGAAGGCCATCATGATGGCCTCTCAGAGTCTCATGTG
TGGGCATCAGGATGTGATGGTGGCAGGTGGGATGGAGAGCATGTCCAATGTCCCCTACGTCATG
AGCAGAGGAGCCACCCCATATGGTGGTGTAAAGCTTGAAGATTTGATTGTAAAAGATGGACTCA
CTGATGTCTACAATAAAATCCATATGGGAAACTGTGCTGAGAACACTGCGAAGAAGATGAACAT
TACACGGGAAGAGCAGGACACGTATGCGCTGAGCTCCTACACCAGGAGTAAAGCGGCGTGGGAG
GCGGGAAGATTTGGAAGTGAAGTGATCCCGGTCACAGTCACAACCAAAGGTAAACCAGATGTAC
TGGTGACAGAAGATGAAGAATATAAACGTGTTGACTTTAGCAAAGTTCCAAAGCTAAAGACAGT
TTTCCAGAAAGAAAATGGCACAGTAACAGCTGCCAACGCAAGCACGCTGAATGATGGTGCTGCG
GCTGTGGTGCTGATGACTGCAGATGCAGCCAGGAGGCTCAAGGTGAAACCGCTGGCAAGAGTAG
CAGCATTTGCTGATGCTGCTGTGGAACCTATTGATTTTCCAGTTGCACCTGCGTATGCTGTACC
TAAGGTTCTTAGAGATGCAGGACTGAAGAAAGAGGACATTACGATGTGGGAAGTAAACGAAGCC
TTTAGCCTGGTTGTACTAGCAAACATCAAAATGCTGGACCTGGACCCCCAAAAAGTAAACATGA
ATGGAGGAGCTGTTTCTCTGGGACATCCGATTGGGATGTCTGGAGCCAGGATTGTCGTTCACTT
GGTTCATGCCTTGAAGCAGGGAGAATATGGTCTTGCAAGTATTTGCAATGGAGGAGGAGGTGCT
TCTGCCCTGTTGATCCAGAAGCTGTAGACAACTTGTGTCATCCAAAGCACAACAATACTACATG
GATTCTGTAATCATTATGACTGACCACCTGGGTCAGGTTATTCAATCTGTTTCGTTTTCTATTT
TTTTCTAATATTTTTATAAGCAGATAAGATCAGTTCTCAAACCTTCTGAAATTATAAGTTTTTC
TTCCTGTTTTAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_038331079	(Get FASTA)	NCBI Sequence Viewer
	XP_038331081	(Get FASTA)	NCBI Sequence Viewer
	XP_038331082	(Get FASTA)	NCBI Sequence Viewer
	XP_038367601	(Get FASTA)	NCBI Sequence Viewer
	XP_038367610	(Get FASTA)	NCBI Sequence Viewer
	XP_038392211	(Get FASTA)	NCBI Sequence Viewer
	XP_038392212	(Get FASTA)	NCBI Sequence Viewer
	XP_038392213	(Get FASTA)	NCBI Sequence Viewer
	XP_038456410	(Get FASTA)	NCBI Sequence Viewer
	XP_038456411	(Get FASTA)	NCBI Sequence Viewer
	XP_038456412	(Get FASTA)	NCBI Sequence Viewer
	XP_038520938	(Get FASTA)	NCBI Sequence Viewer
	XP_038520939	(Get FASTA)	NCBI Sequence Viewer
	XP_038520940	(Get FASTA)	NCBI Sequence Viewer
	XP_546539	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000021489.5
	ENSCAFP00000035863.2
	ENSCAFP00000069284.1
	ENSCAFP00000074530.1
	ENSCAFP00000074691.1
	ENSCAFP00030029588.1
	ENSCAFP00040019847.1
	ENSCAFP00040019868.1
	ENSCAFP00040019932.1
	ENSCAFP00845005065.1
	ENSCAFP00845005068.1
	ENSCAFP00845005080
	ENSCAFP00845005080.1
	ENSCAFP00845005087.1

RefSeq Acc Id:	XP_546539 ⟸ XM_546539
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0K0D5 (UniProtKB/TrEMBL), A0A8C0YWR8 (UniProtKB/TrEMBL), A0A8I3MQ37 (UniProtKB/TrEMBL), A0A8P0TLF2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGTCILDLPPGKTSGVVENARARLVRRVCQAVRYVERSYVSKPTLNEVVIVSAARTPIGSFLGS LSSLPATKLGSIAIQGVIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAALGAGLPISTPCTTV NKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMSRGATPYGGVKLEDLIVKDGLTD VYNKIHMGNCAENTAKKMNITREEQDTYALSSYTRSKAAWEAGRFGSEVIPVTVTTKGKPDVLV TEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAAVVLMTADAARRLKVKPLARVAA FADAAVEPIDFPVAPAYAVPKVLRDAGLKKEDITMWEVNEAFSLVVLANIKMLDLDPQKVNMNG GAVSLGHPIGMSGARIVVHLVHALKQGEYGLASICNGGGGASALLIQKL hide sequence

RefSeq Acc Id:

ENSCAFP00000035863 ⟸ ENSCAFT00000047270

RefSeq Acc Id:

ENSCAFP00000021489 ⟸ ENSCAFT00000023145

RefSeq Acc Id:	XP_038331081 ⟸ XM_038475153
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038331082 ⟸ XM_038475154
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038331079 ⟸ XM_038475151
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038456411 ⟸ XM_038600483
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038456412 ⟸ XM_038600484
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038456410 ⟸ XM_038600482
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038520939 ⟸ XM_038665011
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0K0I4 (UniProtKB/TrEMBL), A0A8C0RN66 (UniProtKB/TrEMBL), A0A8I3RSY6 (UniProtKB/TrEMBL), A0A8I3MQ37 (UniProtKB/TrEMBL), A0A8P0TLF2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038520940 ⟸ XM_038665012
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I3MQ37 (UniProtKB/TrEMBL), A0A8P0TLF2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038520938 ⟸ XM_038665010
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0K0D5 (UniProtKB/TrEMBL), A0A8C0YWR8 (UniProtKB/TrEMBL), A0A8I3MQ37 (UniProtKB/TrEMBL), A0A8P0TLF2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038367601 ⟸ XM_038511673
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0K0I4 (UniProtKB/TrEMBL), A0A8C0RN66 (UniProtKB/TrEMBL), A0A8I3RSY6 (UniProtKB/TrEMBL), A0A8I3MQ37 (UniProtKB/TrEMBL), A0A8P0TLF2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038367610 ⟸ XM_038511682
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I3MQ37 (UniProtKB/TrEMBL), A0A8P0TLF2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038392212 ⟸ XM_038536284
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0K0I4 (UniProtKB/TrEMBL), A0A8C0RN66 (UniProtKB/TrEMBL), A0A8I3MQ37 (UniProtKB/TrEMBL), A0A8I3RSY6 (UniProtKB/TrEMBL), A0A8P0TLF2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038392213 ⟸ XM_038536285
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I3MQ37 (UniProtKB/TrEMBL), A0A8P0TLF2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038392211 ⟸ XM_038536283
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0K0D5 (UniProtKB/TrEMBL), A0A8C0YWR8 (UniProtKB/TrEMBL), A0A8I3MQ37 (UniProtKB/TrEMBL), A0A8P0TLF2 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845005065 ⟸ ENSCAFT00845006376

RefSeq Acc Id:

ENSCAFP00845005068 ⟸ ENSCAFT00845006382

RefSeq Acc Id:

ENSCAFP00845005087 ⟸ ENSCAFT00845006403

RefSeq Acc Id:

ENSCAFP00845005080 ⟸ ENSCAFT00845006396

Protein Domains

Thiolase C-terminal Thiolase N-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000014570	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030018438	UniProtKB/TrEMBL
	ENSCAFG00040012438	UniProtKB/TrEMBL
	ENSCAFG00845003582	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000023145.5	UniProtKB/TrEMBL
	ENSCAFT00000047270.4	UniProtKB/TrEMBL
	ENSCAFT00000097404.1	UniProtKB/TrEMBL
	ENSCAFT00000108605.1	UniProtKB/TrEMBL
	ENSCAFT00000109888.1	UniProtKB/TrEMBL
	ENSCAFT00030033932.1	UniProtKB/TrEMBL
	ENSCAFT00040022905.1	UniProtKB/TrEMBL
	ENSCAFT00040022928.1	UniProtKB/TrEMBL
	ENSCAFT00040022996.1	UniProtKB/TrEMBL
	ENSCAFT00845006376.1	UniProtKB/TrEMBL
	ENSCAFT00845006382.1	UniProtKB/TrEMBL
	ENSCAFT00845006396	ENTREZGENE
	ENSCAFT00845006396.1	UniProtKB/TrEMBL
	ENSCAFT00845006403.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.47.10	UniProtKB/TrEMBL
InterPro	Thiolase	UniProtKB/TrEMBL
	Thiolase-like	UniProtKB/TrEMBL
	Thiolase_acyl_enz_int_AS	UniProtKB/TrEMBL
	Thiolase_AS	UniProtKB/TrEMBL
	Thiolase_C	UniProtKB/TrEMBL
	Thiolase_CS	UniProtKB/TrEMBL
	Thiolase_N	UniProtKB/TrEMBL
NCBI Gene	ACAT1	ENTREZGENE
PANTHER	ACETYL-COA ACETYLTRANSFERASE, MITOCHONDRIAL	UniProtKB/TrEMBL
	ACETYL-COA C-ACYLTRANSFERASE	UniProtKB/TrEMBL
Pfam	Thiolase_C	UniProtKB/TrEMBL
	Thiolase_N	UniProtKB/TrEMBL
PIRSF	Ac-CoA_Ac_transf	UniProtKB/TrEMBL
PROSITE	THIOLASE_1	UniProtKB/TrEMBL
	THIOLASE_2	UniProtKB/TrEMBL
	THIOLASE_3	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53901	UniProtKB/TrEMBL
UniProt	A0A8C0K0D5	ENTREZGENE
	A0A8C0K0I4	ENTREZGENE
	A0A8C0RN66	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0SEC6_CANLF	UniProtKB/TrEMBL
	A0A8C0YWR8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MQ37	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MRP7_CANLF	UniProtKB/TrEMBL
	A0A8I3RSY4_CANLF	UniProtKB/TrEMBL
	A0A8I3RSY6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0PRV1_CANLF	UniProtKB/TrEMBL
	A0A8P0PS20_CANLF	UniProtKB/TrEMBL
	A0A8P0TLF2	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	A0A8P0NG74	UniProtKB/TrEMBL
VGNC ID	VGNC:37498	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB