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Gene: Edc3 (enhancer of mRNA decapping 3) Rattus norvegicus
Symbol: Edc3
Name: enhancer of mRNA decapping 3
RGD ID: 1306898
Description: Predicted to have identical protein binding activity; mRNA binding activity; and phosphodiesterase decapping endonuclease activity. Predicted to be involved in P-body assembly and deadenylation-independent decapping of nuclear-transcribed mRNA. Predicted to localize to P-body. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human EDC3 (enhancer of mRNA decapping 3); PARTICIPATES IN microRNA pathway; INTERACTS WITH amphetamine; bisphenol A; fenvalerate.
Type: protein-coding
RefSeq Status: MODEL
Also known as: enhancer of mRNA decapping 3 homolog; enhancer of mRNA decapping 3 homolog (S. cerevisiae); enhancer of mRNA-decapping protein 3; LOC315708; Lsm16; LSM16 homolog (EDC3, S. cerevisiae); RGD1306898; similar to cDNA clone MGC:36552
Homo sapiens (human) : EDC3 (enhancer of mRNA decapping 3)  HGNC  Alliance
Mus musculus (house mouse) : Edc3 (enhancer of mRNA decapping 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Edc3 (enhancer of mRNA decapping 3)
Pan paniscus (bonobo/pygmy chimpanzee) : EDC3 (enhancer of mRNA decapping 3)
Canis lupus familiaris (dog) : EDC3 (enhancer of mRNA decapping 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Edc3 (enhancer of mRNA decapping 3)
Sus scrofa (pig) : EDC3 (enhancer of mRNA decapping 3)
Chlorocebus sabaeus (African green monkey) : EDC3 (enhancer of mRNA decapping 3)
Heterocephalus glaber (naked mole-rat) : Edc3 (enhancer of mRNA decapping 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0862,482,126 - 62,527,665 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl862,482,140 - 62,526,202 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0862,259,090 - 62,304,624 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4861,472,266 - 61,517,590 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1861,527,057 - 61,536,217 (+)NCBI
Celera857,571,854 - 57,617,320 (+)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Edc3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306898
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-11-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.