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Gene: Edc3 (enhancer of mRNA decapping 3) Rattus norvegicus
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Symbol: Edc3
Name: enhancer of mRNA decapping 3
Description: Predicted to have identical protein binding activity; mRNA binding activity; and phosphodiesterase decapping endonuclease activity. Predicted to be involved in cytoplasmic mRNA processing body assembly and deadenylation-independent decapping of nuclear-transcribed mRNA. Predicted to localize to the P-body. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human EDC3 (enhancer of mRNA decapping 3); PARTICIPATES IN microRNA pathway; INTERACTS WITH (RS)-amphetamine; bisphenol A; ketamine.
Type: protein-coding
RefSeq Status: MODEL
Also known as: enhancer of mRNA decapping 3 homolog; enhancer of mRNA decapping 3 homolog (S. cerevisiae); enhancer of mRNA-decapping protein 3; LOC315708; Lsm16; LSM16 homolog (EDC3, S. cerevisiae); RGD1306898; similar to cDNA clone MGC:36552
Orthologs:
Homo sapiens (human) : EDC3 (enhancer of mRNA decapping 3)  HGNC  Alliance
Mus musculus (house mouse) : Edc3 (enhancer of mRNA decapping 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Edc3 (enhancer of mRNA decapping 3)
Pan paniscus (bonobo/pygmy chimpanzee) : EDC3 (enhancer of mRNA decapping 3)
Canis lupus familiaris (dog) : EDC3 (enhancer of mRNA decapping 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Edc3 (enhancer of mRNA decapping 3)
Sus scrofa (pig) : EDC3 (enhancer of mRNA decapping 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0862,482,126 - 62,527,665 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0862,259,090 - 62,304,624 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4861,472,266 - 61,517,590 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1861,527,057 - 61,536,217 (+)NCBI
Celera857,571,854 - 57,617,320 (+)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Edc3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306898
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.