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Gene: Rdx (radixin) Rattus norvegicus
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Symbol: Rdx
Name: radixin
Description: Exhibits actin binding activity. Involved in apical protein localization; barbed-end actin filament capping; and cellular response to platelet-derived growth factor stimulus. Localizes to several cellular components, including the T-tubule; cleavage furrow; and midbody. Predicted to colocalize with the focal adhesion. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 24. Orthologous to human RDX (radixin); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC95168; radixin isoform
Orthologs:
Homo sapiens (human) : RDX (radixin)  HGNC  Alliance
Mus musculus (house mouse) : Rdx (radixin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rdx (radixin)
Pan paniscus (bonobo/pygmy chimpanzee) : RDX (radixin)
Canis lupus familiaris (dog) : RDX (radixin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rdx (radixin)
Sus scrofa (pig) : RDX (radixin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0856,570,728 - 56,612,851 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0855,152,377 - 55,194,097 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4855,404,000 - 55,450,183 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1855,423,053 - 55,469,236 (+)NCBI
Celera851,903,656 - 51,946,436 (+)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Rdx
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1359472
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.