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Gene: Chrnb4 (cholinergic receptor nicotinic beta 4 subunit) Rattus norvegicus
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Symbol: Chrnb4
Name: cholinergic receptor nicotinic beta 4 subunit
Description: Exhibits acetylcholine binding activity. Predicted to contribute to acetylcholine receptor activity and extracellular ligand-gated ion channel activity. Predicted to be involved in several processes, including behavioral response to nicotine; chemical synaptic transmission; and positive regulation of transmission of nerve impulse. Localizes to the acetylcholine-gated channel complex and neuron projection. Orthologous to human CHRNB4 (cholinergic receptor nicotinic beta 4 subunit); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; INTERACTS WITH (S)-anabasine; (S)-nicotine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Acetylcholine receptor beta 4; cholinergic receptor, nicotinic beta 4; cholinergic receptor, nicotinic, beta 4; cholinergic receptor, nicotinic, beta 4 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 4; N-alpha 2; neuronal acetylcholine receptor non-alpha-2 chain; neuronal acetylcholine receptor subunit beta-4
Orthologs:
Allele / Splice: Chrnb4em5Mcwi  
Genetic Models: LEW-Chrnb4em5Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0859,610,489 - 59,629,073 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl859,609,693 - 59,629,133 (-)Ensembl
Rnor_5.0858,192,375 - 58,210,959 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4858,586,961 - 58,605,545 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1858,605,220 - 58,624,659 (-)NCBI
Celera854,902,516 - 54,921,100 (-)NCBICelera
Cytogenetic Map8q24NCBI
RH 3.4 Map8614.4RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Chrnb4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2351
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.