Ibtk (inhibitor of Bruton tyrosine kinase) - Rat Genome Database

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Gene: Ibtk (inhibitor of Bruton tyrosine kinase) Rattus norvegicus
Analyze
Symbol: Ibtk
Name: inhibitor of Bruton tyrosine kinase
RGD ID: 1311697
Description: Predicted to enable protein kinase binding activity and protein tyrosine kinase inhibitor activity. Predicted to be involved in negative regulation of protein phosphorylation. Predicted to act upstream of or within release of sequestered calcium ion into cytosol. Predicted to be active in cytoplasm and nucleoplasm. Orthologous to human IBTK (inhibitor of Bruton tyrosine kinase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; gentamycin.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inhibitor of Bruton agammaglobulinemia tyrosine kinase; LOC315858
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2886,625,591 - 86,698,661 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl886,625,597 - 86,698,260 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0893,323,454 - 93,397,044 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl893,324,476 - 93,390,305 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0892,839,700 - 92,912,381 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4890,907,477 - 90,973,991 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1890,958,744 - 90,993,464 (-)NCBI
Celera886,239,546 - 86,312,431 (-)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,ISO)
nucleoplasm  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11577348  


Genomics

Comparative Map Data
Ibtk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2886,625,591 - 86,698,661 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl886,625,597 - 86,698,260 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0893,323,454 - 93,397,044 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl893,324,476 - 93,390,305 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0892,839,700 - 92,912,381 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4890,907,477 - 90,973,991 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1890,958,744 - 90,993,464 (-)NCBI
Celera886,239,546 - 86,312,431 (-)NCBICelera
Cytogenetic Map8q31NCBI
IBTK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38682,169,987 - 82,247,744 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl682,169,986 - 82,247,754 (-)EnsemblGRCh38hg38GRCh38
GRCh37682,879,704 - 82,957,461 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36682,936,675 - 83,014,167 (-)NCBINCBI36Build 36hg18NCBI36
Build 34682,936,674 - 83,014,167NCBI
Celera683,302,847 - 83,380,340 (-)NCBICelera
Cytogenetic Map6q14.1NCBI
HuRef680,097,712 - 80,175,203 (-)NCBIHuRef
CHM1_1682,977,539 - 83,055,017 (-)NCBICHM1_1
T2T-CHM13v2.0683,379,383 - 83,457,139 (-)NCBIT2T-CHM13v2.0
Ibtk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39985,569,412 - 85,632,756 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl985,569,413 - 85,631,387 (-)EnsemblGRCm39 Ensembl
GRCm38985,687,359 - 85,750,703 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl985,687,360 - 85,749,334 (-)EnsemblGRCm38mm10GRCm38
MGSCv37985,580,963 - 85,637,766 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36985,484,074 - 85,547,147 (-)NCBIMGSCv36mm8
Celera982,775,459 - 82,832,450 (-)NCBICelera
Cytogenetic Map9E3.1NCBI
Ibtk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541110,051,296 - 10,132,203 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541110,052,584 - 10,132,203 (-)NCBIChiLan1.0ChiLan1.0
IBTK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1683,325,428 - 83,402,670 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl683,325,428 - 83,402,670 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0680,061,649 - 80,139,393 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
IBTK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11242,670,082 - 42,771,179 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1242,671,543 - 42,760,546 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1242,549,625 - 42,649,820 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01243,439,487 - 43,539,739 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1243,439,714 - 43,539,711 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11242,757,941 - 42,857,979 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01242,727,666 - 42,827,806 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01242,882,252 - 42,982,454 (-)NCBIUU_Cfam_GSD_1.0
Ibtk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494678,047,382 - 78,125,029 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365108,346,357 - 8,423,487 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049365108,345,182 - 8,425,080 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IBTK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl183,973,582 - 84,070,554 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1183,973,541 - 84,070,751 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2194,512,575 - 94,609,704 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IBTK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1136,836,527 - 6,915,731 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl136,834,532 - 6,915,778 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040183,063,575 - 183,142,721 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ibtk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479912,330,559 - 12,413,080 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479912,325,164 - 12,412,958 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ibtk
255 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:443
Count of miRNA genes:213
Interacting mature miRNAs:247
Transcripts:ENSRNOT00000038415, ENSRNOT00000056930
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)82720571599103503Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)82720571599103503Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)83018886794457446Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83646953599083736Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84071306693965294Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)84329616998968765Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)84329616998968765Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)84329616998968765Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)84329616998968765Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)84329616998968765Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)84329616998968765Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088624Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)84653172299083736Rat
2303570Gluco48Glucose level QTL 482blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)84980583194805831Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)851351728107062046Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)85404374498968765Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)85423764499103503Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)854259986100382532Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat

Markers in Region
D8Got134  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2886,686,385 - 86,686,523 (+)MAPPERmRatBN7.2
Rnor_6.0893,383,738 - 93,383,875NCBIRnor6.0
Rnor_5.0892,899,093 - 92,899,230UniSTSRnor5.0
RGSC_v3.4890,967,381 - 90,967,518UniSTSRGSC3.4
Celera886,299,430 - 86,299,567UniSTS
Cytogenetic Map8q31UniSTS
AI548552  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2886,625,482 - 86,625,663 (+)MAPPERmRatBN7.2
Rnor_6.0893,323,346 - 93,323,526NCBIRnor6.0
Rnor_5.0892,839,592 - 92,839,772UniSTSRnor5.0
RGSC_v3.4890,907,666 - 90,907,846UniSTSRGSC3.4
Celera886,239,438 - 86,239,618UniSTS
RH 3.4 Map8987.9UniSTS
Cytogenetic Map8q31UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 41 57 41 19 41 8 11 74 35 37 11 8
Low 1 2 4
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000056930   ⟹   ENSRNOP00000053769
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl886,626,213 - 86,698,260 (-)Ensembl
Rnor_6.0 Ensembl893,324,476 - 93,390,305 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000116914   ⟹   ENSRNOP00000081930
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl886,625,597 - 86,698,260 (-)Ensembl
RefSeq Acc Id: XM_039082544   ⟹   XP_038938472
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2886,625,591 - 86,698,641 (-)NCBI
RefSeq Acc Id: XM_039082545   ⟹   XP_038938473
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2886,625,591 - 86,698,642 (-)NCBI
RefSeq Acc Id: XM_039082546   ⟹   XP_038938474
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2886,660,163 - 86,698,661 (-)NCBI
RefSeq Acc Id: XM_039082547   ⟹   XP_038938475
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2886,625,591 - 86,670,843 (-)NCBI
Protein Sequences
Protein RefSeqs XP_038938472 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938473 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938474 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938475 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL77645 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: ENSRNOP00000053769   ⟸   ENSRNOT00000056930
RefSeq Acc Id: XP_038938473   ⟸   XM_039082545
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZUJ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938472   ⟸   XM_039082544
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038938475   ⟸   XM_039082547
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038938474   ⟸   XM_039082546
- Peptide Label: isoform X3
RefSeq Acc Id: ENSRNOP00000081930   ⟸   ENSRNOT00000116914
Protein Domains
BTB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZH46-F1-model_v2 AlphaFold D3ZH46 1-1350 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311697 AgrOrtholog
BioCyc Gene G2FUF-29657 BioCyc
Ensembl Genes ENSRNOG00000027728 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000053769 ENTREZGENE
  ENSRNOP00000053769.5 UniProtKB/TrEMBL
  ENSRNOP00000081930 ENTREZGENE
  ENSRNOP00000081930.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000056930 ENTREZGENE
  ENSRNOT00000056930.6 UniProtKB/TrEMBL
  ENSRNOT00000116914 ENTREZGENE
  ENSRNOT00000116914.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
  2.130.10.30 UniProtKB/TrEMBL
  3.30.710.10 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  BTB/POZ-like UniProtKB/TrEMBL
  BTB/POZ_fold UniProtKB/TrEMBL
  Reg_chr_condens UniProtKB/TrEMBL
  Reg_csome_cond/b-lactamase_inh UniProtKB/TrEMBL
NCBI Gene 315858 ENTREZGENE
Pfam Ank_2 UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  RCC1 UniProtKB/TrEMBL
PhenoGen Ibtk PhenoGen
PROSITE ANK_REPEAT UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  RCC1_3 UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
Superfamily-SCOP ANK UniProtKB/TrEMBL
  BTB/POZ_fold UniProtKB/TrEMBL
  RCC1/BLIP-II UniProtKB/TrEMBL
UniProt A0A8I5ZUJ7 ENTREZGENE, UniProtKB/TrEMBL
  D3ZH46_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-02 Ibtk  inhibitor of Bruton tyrosine kinase  Ibtk  inhibitor of Bruton agammaglobulinemia tyrosine kinase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ibtk  inhibitor of Bruton agammaglobulinemia tyrosine kinase   Ibtk_predicted  inhibitor of Bruton agammaglobulinemia tyrosine kinase (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ibtk_predicted  inhibitor of Bruton agammaglobulinemia tyrosine kinase (predicted)      Symbol and Name status set to approved 70820 APPROVED