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Gene: Ibtk (inhibitor of Bruton tyrosine kinase) Rattus norvegicus
Symbol: Ibtk
Name: inhibitor of Bruton tyrosine kinase
Description: Predicted to have protein kinase binding activity and protein tyrosine kinase inhibitor activity. Predicted to be involved in negative regulation of protein phosphorylation and release of sequestered calcium ion into cytosol. Predicted to localize to the cytoplasm and nucleoplasm. Orthologous to human IBTK (inhibitor of Bruton tyrosine kinase); INTERACTS WITH bisphenol A; methapyrilene; oxaliplatin.
Type: protein-coding
RefSeq Status: MODEL
Also known as: inhibitor of Bruton agammaglobulinemia tyrosine kinase; LOC315858; LOW QUALITY PROTEIN: inhibitor of Bruton tyrosine kinase
Homo sapiens (human) : IBTK (inhibitor of Bruton tyrosine kinase)  HGNC  Alliance
Mus musculus (house mouse) : Ibtk (inhibitor of Bruton agammaglobulinemia tyrosine kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ibtk (inhibitor of Bruton tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : IBTK (inhibitor of Bruton tyrosine kinase)
Canis lupus familiaris (dog) : IBTK (inhibitor of Bruton tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ibtk (inhibitor of Bruton tyrosine kinase)
Sus scrofa (pig) : IBTK (inhibitor of Bruton tyrosine kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0893,323,454 - 93,397,044 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl893,324,476 - 93,390,305 (-)Ensembl
Rnor_5.0892,839,700 - 92,912,381 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4890,907,477 - 90,973,991 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1890,958,744 - 90,993,464 (-)NCBI
Celera886,239,546 - 86,312,431 (-)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Ibtk
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311697
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.