Gene: Chrna5 (cholinergic receptor nicotinic alpha 5 subunit) Rattus norvegicus
Symbol: Chrna5
Name: cholinergic receptor nicotinic alpha 5 subunit
Description: ENCODES a protein that exhibits acetylcholine binding; acetylcholine-gated cation-selective channel activity; protein heterodimerization activity; INVOLVED IN behavioral response to nicotine (ortholog); response to nicotine (ortholog); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; ASSOCIATED WITH Alcoholism (ortholog); Anxiety Disorders (ortholog); Lung Neoplasms (ortholog); FOUND IN acetylcholine-gated channel complex; dendrite; neuronal cell body; INTERACTS WITH ammonium chloride; bisphenol A; chlorpyrifos
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Acetylcholine receptor alpha 5; cetylcholine receptor alpha 5; cholinergic receptor, nicotinic, alpha 5; cholinergic receptor, nicotinic, alpha 5 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 5; neuronal acetylcholine receptor subunit alpha-5
Homo sapiens (human) : CHRNA5 (cholinergic receptor nicotinic alpha 5 subunit)  HGNC  Alliance
Mus musculus (house mouse) : Chrna5 (cholinergic receptor, nicotinic, alpha polypeptide 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chrna5 (cholinergic receptor nicotinic alpha 5 subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : CHRNA5 (cholinergic receptor nicotinic alpha 5 subunit)
Canis lupus familiaris (dog) : CHRNA5 (cholinergic receptor nicotinic alpha 5 subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chrna5 (cholinergic receptor nicotinic alpha 5 subunit)
more info ...
Allele / Splice: Chrna5em1Mcwi   Chrna5em2Mcwi  
Genetic Models: LEW-Chrna5em2Mcwi LEW-Chrna5em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0859,561,817 - 59,590,172 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0858,143,974 - 58,172,330 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4858,538,002 - 58,566,388 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1858,557,055 - 58,585,442 (+)NCBI
Celera854,856,809 - 54,885,137 (+)NCBICelera
Cytogenetic Map8q24NCBI
RH 3.4 Map8615.2RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Chrna5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2347
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-03-13
Status: ACTIVE