Snap91 (synaptosome associated protein 91) - Rat Genome Database

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Gene: Snap91 (synaptosome associated protein 91) Rattus norvegicus
Analyze
Symbol: Snap91
Name: synaptosome associated protein 91
RGD ID: 69276
Description: Enables several functions, including SH2 domain binding activity; anion binding activity; and clathrin binding activity. Involved in several processes, including negative regulation of phospholipase activity; positive regulation of cellular component organization; and positive regulation of synaptic vesicle clustering. Located in several cellular components, including cytoplasmic vesicle; postsynaptic density; and presynaptic active zone membrane. Is active in Schaffer collateral - CA1 synapse; parallel fiber to Purkinje cell synapse; and postsynaptic membrane. Is extrinsic component of presynaptic endocytic zone membrane. Biomarker of middle cerebral artery infarction. Orthologous to human SNAP91 (synaptosome associated protein 91); PARTICIPATES IN clathrin-dependent synaptic vesicle endocytosis; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 91 kDa synaptosomal-associated protein; Ap180; assembly protein 180 (AP180); clathrin coat assembly protein AP180; clathrin coat-associated protein AP180; synaptosomal-associated protein 91; synaptosomal-associated protein 91 kDa; synaptosomal-associated protein, 91 kDa; synaptosomal-associated protein, 91kDa homolog; synaptosomal-associated protein, 91kDa homolog (mouse)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2887,738,056 - 87,852,690 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl887,738,824 - 87,852,367 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx893,418,568 - 93,525,116 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0891,617,774 - 91,724,331 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0889,459,489 - 89,566,103 (-)NCBIRnor_WKY
Rnor_6.0894,447,558 - 94,564,772 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl894,447,550 - 94,564,525 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0893,958,152 - 94,074,269 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4892,033,425 - 92,147,091 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1892,052,879 - 92,166,546 (-)NCBI
Celera887,338,970 - 87,446,775 (-)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. A-single spermatogonia heterogeneity and cell cycles synchronize with rat seminiferous epithelium stages VIII-IX. Abid SN, etal., Biol Reprod. 2014 Feb 13;90(2):32. doi: 10.1095/biolreprod.113.113555. Print 2014 Feb.
2. Accessory protein recruitment motifs in clathrin-mediated endocytosis. Brett TJ, etal., Structure. 2002 Jun;10(6):797-809.
3. Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons. Bushlin I, etal., J Neurosci. 2008 Oct 8;28(41):10257-71. doi: 10.1523/JNEUROSCI.2471-08.2008.
4. Changed clathrin regulatory proteins in the brains of Alzheimer's disease patients and animal models. Cao Y, etal., J Alzheimers Dis. 2010;22(1):329-42. doi: 10.3233/JAD-2010-100162.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. AP180 binds to the C-terminal SH2 domain of phospholipase C-gamma1 and inhibits its enzymatic activity. Han SJ, etal., Biochem Biophys Res Commun 2002 Jan 11;290(1):35-41.
7. Unusual structural organization of the endocytic proteins AP180 and epsin 1. Kalthoff C, etal., J Biol Chem. 2002 Mar 8;277(10):8209-16. Epub 2001 Dec 26.
8. SNARE motif-mediated sorting of synaptobrevin by the endocytic adaptors clathrin assembly lymphoid myeloid leukemia (CALM) and AP180 at synapses. Koo SJ, etal., Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13540-5. doi: 10.1073/pnas.1107067108. Epub 2011 Aug 1.
9. Inhibition of phospholipase D by clathrin assembly protein 3 (AP3). Lee C, etal., J Biol Chem. 1997 Jun 20;272(25):15986-92.
10. Cloning and expression of a novel member of the low voltage-activated T-type calcium channel family. Lee JH, etal., J Neurosci 1999 Mar 15;19(6):1912-21.
11. Clathrin assembly protein AP180: primary structure, domain organization and identification of a clathrin binding site. Morris SA, etal., EMBO J 1993 Feb;12(2):667-75.
12. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. Inositol hexakisphosphate binds to clathrin assembly protein 3 (AP-3/AP180) and inhibits clathrin cage assembly in vitro. Norris FA, etal., J Biol Chem. 1995 Jan 6;270(1):214-7.
14. AP180 and CALM in the developing hippocampus: expression at the nascent synapse and localization to trafficking organelles. Petralia RS and Yao PJ, J Comp Neurol. 2007 Sep 20;504(3):314-27.
15. Reduction of AP180 and CALM produces defects in synaptic vesicle size and density. Petralia RS, etal., Neuromolecular Med. 2013 Mar;15(1):49-60. doi: 10.1007/s12017-012-8194-x. Epub 2012 Aug 1.
16. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
17. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
18. The NECAP PHear domain increases clathrin accessory protein binding potential. Ritter B, etal., EMBO J. 2007 Sep 19;26(18):4066-77. Epub 2007 Aug 30.
19. Calpain hydrolysis of alpha- and beta2-adaptins decreases clathrin-dependent endocytosis and may promote neurodegeneration. Rudinskiy N, etal., J Biol Chem. 2009 May 1;284(18):12447-58. doi: 10.1074/jbc.M804740200. Epub 2009 Feb 24.
20. Synaptic vesicle endocytosis. Saheki Y and De Camilli P, Cold Spring Harb Perspect Biol. 2012 Sep 1;4(9):a005645. doi: 10.1101/cshperspect.a005645.
21. Clathrin assembly proteins AP180 and CALM in the embryonic rat brain. Schwartz CM, etal., J Comp Neurol. 2010 Sep 15;518(18):3803-18. doi: 10.1002/cne.22425.
22. Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly. Traub LM, etal., Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8907-12.
23. Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Wilhelm BG, etal., Science. 2014 May 30;344(6187):1023-8. doi: 10.1126/science.1252884.
24. High-resolution localization of clathrin assembly protein AP180 in the presynaptic terminals of mammalian neurons. Yao PJ, etal., J Comp Neurol 2002 May 27;447(2):152-62.
25. Synaptic distribution of the endocytic accessory proteins AP180 and CALM. Yao PJ, etal., J Comp Neurol. 2005 Jan 3;481(1):58-69.
Additional References at PubMed
PMID:9045662   PMID:10428863   PMID:11102472   PMID:16025302   PMID:16254249   PMID:16903783   PMID:20937255   PMID:21307259   PMID:21500857   PMID:22871113   PMID:26412491   PMID:29476059  
PMID:32357304  


Genomics

Comparative Map Data
Snap91
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2887,738,056 - 87,852,690 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl887,738,824 - 87,852,367 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx893,418,568 - 93,525,116 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0891,617,774 - 91,724,331 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0889,459,489 - 89,566,103 (-)NCBIRnor_WKY
Rnor_6.0894,447,558 - 94,564,772 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl894,447,550 - 94,564,525 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0893,958,152 - 94,074,269 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4892,033,425 - 92,147,091 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1892,052,879 - 92,166,546 (-)NCBI
Celera887,338,970 - 87,446,775 (-)NCBICelera
Cytogenetic Map8q31NCBI
SNAP91
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38683,552,885 - 83,709,393 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl683,552,880 - 83,709,691 (-)EnsemblGRCh38hg38GRCh38
GRCh37684,262,604 - 84,419,112 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36684,319,332 - 84,475,495 (-)NCBINCBI36Build 36hg18NCBI36
Build 34684,319,331 - 84,475,495NCBI
Celera684,695,893 - 84,852,438 (-)NCBICelera
Cytogenetic Map6q14.2NCBI
HuRef681,492,256 - 81,648,799 (-)NCBIHuRef
CHM1_1684,360,208 - 84,516,740 (-)NCBICHM1_1
T2T-CHM13v2.0684,776,120 - 84,932,636 (-)NCBIT2T-CHM13v2.0
Snap91
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39986,647,976 - 86,762,766 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl986,647,976 - 86,762,707 (-)EnsemblGRCm39 Ensembl
GRCm38986,765,923 - 86,880,734 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl986,765,923 - 86,880,654 (-)EnsemblGRCm38mm10GRCm38
MGSCv37986,659,239 - 86,775,207 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36986,562,350 - 86,678,320 (-)NCBIMGSCv36mm8
Celera983,843,031 - 83,967,649 (-)NCBICelera
Cytogenetic Map9E3.1NCBI
Snap91
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541111,175,525 - 11,300,950 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541111,175,587 - 11,301,145 (-)NCBIChiLan1.0ChiLan1.0
SNAP91
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1684,717,271 - 84,875,561 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl684,720,850 - 84,874,407 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0681,441,792 - 81,600,505 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
SNAP91
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11243,919,925 - 44,058,315 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1243,919,925 - 44,058,616 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1243,734,660 - 43,872,902 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01244,689,016 - 44,828,781 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1244,689,023 - 44,828,948 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11244,027,843 - 44,166,268 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01243,961,559 - 44,100,121 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01244,138,511 - 44,276,836 (-)NCBIUU_Cfam_GSD_1.0
Snap91
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494679,125,757 - 79,248,750 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365107,222,200 - 7,345,138 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SNAP91
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl182,541,018 - 82,698,633 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1182,540,998 - 82,698,652 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2192,790,018 - 92,949,958 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SNAP91
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1138,221,601 - 8,374,205 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666040184,439,639 - 184,590,396 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Snap91
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479910,915,477 - 11,060,312 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479910,913,834 - 11,060,185 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
RH138297  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2887,770,977 - 87,771,142 (+)MAPPERmRatBN7.2
Rnor_6.0894,483,139 - 94,483,303NCBIRnor6.0
Rnor_5.0893,992,946 - 93,993,110UniSTSRnor5.0
RGSC_v3.4892,065,627 - 92,065,791UniSTSRGSC3.4
Celera887,371,070 - 87,371,234UniSTS
RH 3.4 Map81020.8UniSTS
Cytogenetic Map8q31UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)82720571599103503Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)82720571599103503Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)83018886794457446Rat
1578755Pur5Proteinuria QTL 53.30.0001total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83646953599083736Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84071306693965294Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)84329616998968765Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)84329616998968765Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)84329616998968765Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)84329616998968765Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)84329616998968765Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)84329616998968765Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088624Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)84653172299083736Rat
2303570Gluco48Glucose level QTL 482blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)84980583194805831Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)851351728107062046Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)85404374498968765Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)85423764499103503Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)854259986100382532Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:21
Count of miRNA genes:18
Interacting mature miRNAs:20
Transcripts:ENSRNOT00000032792
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 26 4 68 1
Low 3 17 19 7 19 7 1 1 6 35 39 9 1
Below cutoff 19 19 19 7 8 1 2 7

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_031728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC117045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X68877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X68878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000032792   ⟹   ENSRNOP00000030821
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl887,739,282 - 87,852,367 (-)Ensembl
Rnor_6.0 Ensembl894,453,483 - 94,563,760 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000084437   ⟹   ENSRNOP00000071379
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl887,739,282 - 87,852,367 (-)Ensembl
Rnor_6.0 Ensembl894,447,550 - 94,564,525 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100136   ⟹   ENSRNOP00000088200
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl887,739,282 - 87,852,367 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107255   ⟹   ENSRNOP00000079009
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl887,739,282 - 87,852,367 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000112856   ⟹   ENSRNOP00000095111
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl887,739,282 - 87,852,367 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000113065   ⟹   ENSRNOP00000076368
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl887,739,282 - 87,852,367 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000116531   ⟹   ENSRNOP00000076740
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl887,738,824 - 87,852,367 (-)Ensembl
RefSeq Acc Id: NM_031728   ⟹   NP_113916
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,058 - 87,852,532 (-)NCBI
Rnor_6.0894,448,370 - 94,564,497 (-)NCBI
Rnor_5.0893,958,152 - 94,074,269 (-)NCBI
RGSC_v3.4892,033,425 - 92,147,091 (-)RGD
Celera887,338,970 - 87,446,775 (-)RGD
Sequence:
RefSeq Acc Id: XM_006243491   ⟹   XP_006243553
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,852,527 (-)NCBI
Rnor_6.0894,447,558 - 94,564,649 (-)NCBI
Rnor_5.0893,958,152 - 94,074,269 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006243492   ⟹   XP_006243554
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,852,690 (-)NCBI
Rnor_6.0894,447,558 - 94,564,772 (-)NCBI
Rnor_5.0893,958,152 - 94,074,269 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006243494   ⟹   XP_006243556
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,852,532 (-)NCBI
Rnor_6.0894,447,558 - 94,564,649 (-)NCBI
Rnor_5.0893,958,152 - 94,074,269 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006243495   ⟹   XP_006243557
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,852,532 (-)NCBI
Rnor_6.0894,447,558 - 94,564,650 (-)NCBI
Rnor_5.0893,958,152 - 94,074,269 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006243497   ⟹   XP_006243559
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,852,517 (-)NCBI
Rnor_6.0894,447,558 - 94,564,649 (-)NCBI
Rnor_5.0893,958,152 - 94,074,269 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017595905   ⟹   XP_017451394
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,852,515 (-)NCBI
Rnor_6.0894,447,558 - 94,564,649 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039082106   ⟹   XP_038938034
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,851,630 (-)NCBI
RefSeq Acc Id: XM_039082107   ⟹   XP_038938035
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,852,518 (-)NCBI
RefSeq Acc Id: XM_039082108   ⟹   XP_038938036
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,851,630 (-)NCBI
RefSeq Acc Id: XM_039082109   ⟹   XP_038938037
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,851,630 (-)NCBI
RefSeq Acc Id: XM_039082110   ⟹   XP_038938038
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,852,518 (-)NCBI
RefSeq Acc Id: XM_039082111   ⟹   XP_038938039
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,852,532 (-)NCBI
RefSeq Acc Id: XM_039082112   ⟹   XP_038938040
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,852,532 (-)NCBI
RefSeq Acc Id: XM_039082113   ⟹   XP_038938041
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,852,532 (-)NCBI
RefSeq Acc Id: XM_039082114   ⟹   XP_038938042
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,851,630 (-)NCBI
RefSeq Acc Id: XM_039082115   ⟹   XP_038938043
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,852,518 (-)NCBI
RefSeq Acc Id: XM_039082116   ⟹   XP_038938044
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,852,517 (-)NCBI
RefSeq Acc Id: XM_039082117   ⟹   XP_038938045
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,852,532 (-)NCBI
RefSeq Acc Id: XM_039082118   ⟹   XP_038938046
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,851,455 (-)NCBI
RefSeq Acc Id: XM_039082119   ⟹   XP_038938047
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,852,517 (-)NCBI
RefSeq Acc Id: XM_039082120   ⟹   XP_038938048
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,851,630 (-)NCBI
RefSeq Acc Id: XM_039082121   ⟹   XP_038938049
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2887,738,056 - 87,851,630 (-)NCBI
Protein Sequences
Protein RefSeqs NP_113916 (Get FASTA)   NCBI Sequence Viewer  
  XP_006243553 (Get FASTA)   NCBI Sequence Viewer  
  XP_006243554 (Get FASTA)   NCBI Sequence Viewer  
  XP_006243556 (Get FASTA)   NCBI Sequence Viewer  
  XP_006243557 (Get FASTA)   NCBI Sequence Viewer  
  XP_006243559 (Get FASTA)   NCBI Sequence Viewer  
  XP_017451394 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938034 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938035 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938036 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938037 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938038 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938039 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938040 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938041 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938042 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938043 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938044 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938045 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938046 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938047 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938048 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938049 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA48748 (Get FASTA)   NCBI Sequence Viewer  
  CAA48749 (Get FASTA)   NCBI Sequence Viewer  
  EDL77614 (Get FASTA)   NCBI Sequence Viewer  
  EDL77615 (Get FASTA)   NCBI Sequence Viewer  
  EDL77616 (Get FASTA)   NCBI Sequence Viewer  
  EDL77617 (Get FASTA)   NCBI Sequence Viewer  
  EDL77618 (Get FASTA)   NCBI Sequence Viewer  
  EDL77619 (Get FASTA)   NCBI Sequence Viewer  
  EDL77620 (Get FASTA)   NCBI Sequence Viewer  
  EDL77621 (Get FASTA)   NCBI Sequence Viewer  
  Q05140 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_113916   ⟸   NM_031728
- Sequence:
RefSeq Acc Id: XP_006243554   ⟸   XM_006243492
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006243559   ⟸   XM_006243497
- Peptide Label: isoform X12
- Sequence:
RefSeq Acc Id: XP_006243557   ⟸   XM_006243495
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_006243553   ⟸   XM_006243491
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006243556   ⟸   XM_006243494
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017451394   ⟸   XM_017595905
- Peptide Label: isoform X20
- Sequence:
RefSeq Acc Id: ENSRNOP00000071379   ⟸   ENSRNOT00000084437
RefSeq Acc Id: ENSRNOP00000030821   ⟸   ENSRNOT00000032792
RefSeq Acc Id: XP_038938039   ⟸   XM_039082111
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038938041   ⟸   XM_039082113
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038938045   ⟸   XM_039082117
- Peptide Label: isoform X16
RefSeq Acc Id: XP_038938040   ⟸   XM_039082112
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038938035   ⟸   XM_039082107
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038938043   ⟸   XM_039082115
- Peptide Label: isoform X14
RefSeq Acc Id: XP_038938038   ⟸   XM_039082110
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038938047   ⟸   XM_039082119
- Peptide Label: isoform X18
RefSeq Acc Id: XP_038938044   ⟸   XM_039082116
- Peptide Label: isoform X15
RefSeq Acc Id: XP_038938049   ⟸   XM_039082121
- Peptide Label: isoform X21
RefSeq Acc Id: XP_038938048   ⟸   XM_039082120
- Peptide Label: isoform X19
RefSeq Acc Id: XP_038938037   ⟸   XM_039082109
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038938036   ⟸   XM_039082108
- Peptide Label: isoform X5
- UniProtKB: A0A0G2K0B6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938034   ⟸   XM_039082106
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038938042   ⟸   XM_039082114
- Peptide Label: isoform X13
RefSeq Acc Id: XP_038938046   ⟸   XM_039082118
- Peptide Label: isoform X17
RefSeq Acc Id: ENSRNOP00000076368   ⟸   ENSRNOT00000113065
RefSeq Acc Id: ENSRNOP00000088200   ⟸   ENSRNOT00000100136
RefSeq Acc Id: ENSRNOP00000095111   ⟸   ENSRNOT00000112856
RefSeq Acc Id: ENSRNOP00000076740   ⟸   ENSRNOT00000116531
RefSeq Acc Id: ENSRNOP00000079009   ⟸   ENSRNOT00000107255
Protein Domains
ENTH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q05140-F1-model_v2 AlphaFold Q05140 1-915 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
8 94458297 94458298 C T snv MWF/Hsd (2019)
8 94466734 94466735 G A snv COP/CrCrl (MCW & UW), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), SBH/Ygl (MCW), SBN/Ygl (MCW), SR/JrHsd (MCW), M520/N (MCW), FHH/EurMcwi (RGD), FHL/EurMcwi (RGD), LE/Stm (RGD), LL/MavRrrc (RGD), SBH/Ygl (RGD), SBN/Ygl (RGD), SR/JrHsd (RGD), FHH/EurMcwi (2019), FXLE16/Stm (2020), FXLE18/Stm (2020), LEXF11/Stm (2020), LEXF2B/Stm (2019), LEXF3/Stm (2020), LE/Stm (2019), LL/MavRrrcAek (2020), LEXF10A/StmMcwi (2020), M520/NRrrcMcwi (2019), M520/N (2020), SR/JrHsd (2020), CDS
8 94528484 94528485 T C snv CDR, CDS, ACI/EurMcwi (MCW), COP/CrCrl (MCW & UW), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), GH/OmrMcwi (MCW), SBH/Ygl (MCW), SBN/Ygl (MCW), SR/JrHsd (MCW), SS/JrHsdMcwi (MCW), Buf/N (MCW), M520/N (MCW), MR/N (MCW), ACI/EurMcwi (RGD), BBDP/Wor (RGD), F344/NCrl (RGD), LE/Stm (RGD), LEW/Crl (RGD), LEW/NCrlBR (RGD), LH/MavRrrc (RGD), LN/MavRrrc (RGD), MHS/Gib (RGD), MNS/Gib (RGD), SBH/Ygl (RGD), SBN/Ygl (RGD), SHR/NHsd (RGD), SHRSP/Gcrc (RGD), SR/JrHsd (RGD), WKY/NCrl (RGD), WKY/Gcrc (RGD), WKY/NHsd (RGD), ACI/EurMcwi (2019), ACI/N (2020), BN-Lx/CubMcwi (2019), BN/NHsdMcwi (2020), BN/NHsdMcwi (2019), BN/SsN (2020), BUF/N (2020), BXH2/CubMcwi (2020), BXH3/CubMcwi (2020), DA/OlaHsd (2019), F344/DuCrl (2019), F344/NCrl (2019), F344/N (2020), F344/Stm (2019), FHH/EurMcwi (2019), FXLE16/Stm (2020), FXLE18/Stm (2020), GK/FarMcwi (2019), HXB10/IpcvMcwi (2019), HXB20/IpcvMcwi (2020), HXB2/IpcvMcwi (2019), HXB31/IpcvMcwi (2019), HXB4/IpcvMcwi (2020), LEW/Crl (2019), LEXF11/Stm (2020), LEXF1A/Stm (2019), LEXF1C/Stm (2019), LEXF2B/Stm (2019), LEXF3/Stm (2020), LEXF4/Stm (2020), LE/Stm (2019), LH/MavRrrcAek (2020), LL/MavRrrcAek (2020), LN/MavRrrcAek (2020), LEXF10A/StmMcwi (2020), M520/NRrrcMcwi (2019), M520/N (2020), MR/N (2020), MWF/Hsd (2019), PVG/Seac (2019), SHRSP/A3NCrl (2019), SHR/OlalpcvMcwi (2019), SR/JrHsd (2020), SS/JrHsdMcwi (2019), WAG/RijCrl (2020), WKY/NCrl (2019), WKY/N (2020), WN/N (2020)
8 94528555 94528556 C T snv FHL/EurMcwi (MCW), WN/N (2020), SBN/Ygl (MCW), LE/Stm (RGD), MHS/Gib (RGD), MNS/Gib (RGD), SBH/Ygl (RGD), SBN/Ygl (RGD), FXLE16/Stm (2020), LEW/Crl (2019), LEXF4/Stm (2020), LE/Stm (2019), LEXF10A/StmMcwi (2020), MWF/Hsd (2019), WAG/RijCrl (2020), SBH/Ygl (MCW)


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
8 93976541 93976542 G A snv COP/CrCrl (MCW & UW), KFRS3B/Kyo (KyushuU), FHL/EurMcwi (MCW), SBH/Ygl (MCW), SBN/Ygl (MCW), SR/JrHsd (MCW), LL/MavRrrc (KNAW), SR/JrHsd (KNAW), FHH/EurMcwi (KNAW), FHL/EurMcwi (KNAW), LE/Stm (Illumina) (KNAW), LE/Stm (SOLiD) (KNAW), M520/N (KNAW), SBH/Ygl (KNAW), SBN/Ygl (KNAW), LE/Stm (KyushuU), LEC/Tj (KyushuU), FHH/EurMcwi (MCW)


Assembly: mRatBN7.2

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
8 87746136 87746137 C T snv MWF/Hsd (2019)
8 87754573 87754574 G A snv FXLE16/Stm (2020), FXLE18/Stm (2020), LEXF11/Stm (2020), LEXF2B/Stm (2019), LEXF3/Stm (2020), LL/MavRrrcAek (2020), LEXF10A/StmMcwi (2020), M520/NRrrcMcwi (2019), M520/N (2020), SR/JrHsd (2020), FHH/EurMcwi (2019), LE/Stm (2019)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69276 AgrOrtholog
BioCyc Gene G2FUF-29635 BioCyc
Ensembl Genes ENSRNOG00000023861 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000030821 ENTREZGENE
  ENSRNOP00000030821.6 UniProtKB/TrEMBL
  ENSRNOP00000071379 ENTREZGENE
  ENSRNOP00000071379.2 UniProtKB/TrEMBL
  ENSRNOP00000076368 ENTREZGENE
  ENSRNOP00000076368.1 UniProtKB/TrEMBL
  ENSRNOP00000076740 ENTREZGENE
  ENSRNOP00000076740.1 UniProtKB/TrEMBL
  ENSRNOP00000079009 ENTREZGENE
  ENSRNOP00000079009.1 UniProtKB/TrEMBL
  ENSRNOP00000088200 ENTREZGENE
  ENSRNOP00000088200.1 UniProtKB/TrEMBL
  ENSRNOP00000095111 ENTREZGENE
  ENSRNOP00000095111.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000032792 ENTREZGENE
  ENSRNOT00000032792.6 UniProtKB/TrEMBL
  ENSRNOT00000084437 ENTREZGENE
  ENSRNOT00000084437.2 UniProtKB/TrEMBL
  ENSRNOT00000100136 ENTREZGENE
  ENSRNOT00000100136.1 UniProtKB/TrEMBL
  ENSRNOT00000107255 ENTREZGENE
  ENSRNOT00000107255.1 UniProtKB/TrEMBL
  ENSRNOT00000112856 ENTREZGENE
  ENSRNOT00000112856.1 UniProtKB/TrEMBL
  ENSRNOT00000113065 ENTREZGENE
  ENSRNOT00000113065.1 UniProtKB/TrEMBL
  ENSRNOT00000116531 ENTREZGENE
  ENSRNOT00000116531.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.25.40.90 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ANTH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AP180 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AP180-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Clathrin_AP_dom2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENTH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENTH_VHS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:65178 UniProtKB/Swiss-Prot
NCBI Gene 65178 ENTREZGENE
PANTHER PTHR22951 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR22951:SF4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ANTH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Snap91 PhenoGen
PROSITE ENTH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ENTH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48464 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K0B6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y4X5_RAT UniProtKB/TrEMBL
  A0A8I5Y4X7_RAT UniProtKB/TrEMBL
  A0A8I5ZLY5_RAT UniProtKB/TrEMBL
  A0A8I6A7J5_RAT UniProtKB/TrEMBL
  A0A8I6GL07_RAT UniProtKB/TrEMBL
  AP180_RAT UniProtKB/Swiss-Prot
  F1LRK0_RAT UniProtKB/TrEMBL
  Q05140 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-21 Snap91  synaptosome associated protein 91  Snap91  synaptosomal-associated protein 91  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-18 Snap91  synaptosomal-associated protein 91  Snap91  synaptosomal-associated protein, 91kDa homolog (mouse)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Snap91  synaptosomal-associated protein, 91kDa homolog (mouse)    synaptosomal-associated protein, 91 kDa  Name updated 1299863 APPROVED
2002-06-10 Snap91  synaptosomal-associated protein, 91 kDa      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference