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Gene: Apoa5 (apolipoprotein A5) Rattus norvegicus
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Symbol: Apoa5
Name: apolipoprotein A5
Description: Predicted to have several functions, including anion binding activity; cholesterol binding activity; and enzyme regulator activity. Involved in animal organ regeneration; lipid transport; and response to hormone. Localizes to the extracellular space. Biomarker of hypothyroidism. Human ortholog(s) of this gene implicated in cerebral infarction; coronary artery disease; hyperlipoproteinemia type IV; hyperlipoproteinemia type V; and type 2 diabetes mellitus. Orthologous to human APOA5 (apolipoprotein A5); PARTICIPATES IN lipoprotein metabolic pathway; eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; INTERACTS WITH 17alpha-ethynylestradiol; acrylamide; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: apo-AV; apoA-V; apolipoprotein A-V; MGC108612; regeneration-associated protein 3
Orthologs:
Homo sapiens (human) : APOA5 (apolipoprotein A5)  HGNC  Alliance
Mus musculus (house mouse) : Apoa5 (apolipoprotein A-V)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Apoa5 (apolipoprotein A5)
Pan paniscus (bonobo/pygmy chimpanzee) : APOA5 (apolipoprotein A5)
Canis lupus familiaris (dog) : APOA5 (apolipoprotein A5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Apoa5 (apolipoprotein A5)
Sus scrofa (pig) : APOA5 (apolipoprotein A5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0850,559,079 - 50,561,720 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0849,185,041 - 49,187,682 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4849,253,538 - 49,255,777 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1849,265,341 - 49,267,579 (+)NCBI
Celera846,142,946 - 46,145,584 (+)NCBICelera
Cytogenetic Map8q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Apoa5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70903
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.