Gene: Bckdhb (branched chain keto acid dehydrogenase E1 subunit beta) Rattus norvegicus
Symbol: Bckdhb
Name: branched chain keto acid dehydrogenase E1 subunit beta
Description: ENCODES a protein that exhibits protein-containing complex binding; alpha-ketoacid dehydrogenase activity (ortholog); INVOLVED IN response to cAMP; response to glucocorticoid; response to nutrient; PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental ; lung cancer (ortholog); maple syrup urine disease (ortholog); FOUND IN mitochondrial alpha-ketoglutarate dehydrogenase complex (ortholog); mitochondrion (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,4-dinitrotoluene; ammonium chloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2-oxoisovalerate dehydrogenase beta subunit; 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial; BCKDE1B; BCKDH E1-beta; branched chain keto acid dehydrogenase E1 beta; branched chain keto acid dehydrogenase E1, beta polypeptide; branched-chain alpha-keto acid dehydrogenase E1 component beta chain
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0891,464,229 - 91,656,134 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0890,982,516 - 91,173,706 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4888,997,979 - 89,191,017 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1889,017,545 - 89,210,461 (+)NCBI
Celera884,492,980 - 84,673,845 (+)NCBICelera
Cytogenetic Map8q31NCBI
RH 3.4 Map8981.4RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Bckdhb
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2197
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-08-14
Status: ACTIVE