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Gene: Ppib (peptidylprolyl isomerase B) Rattus norvegicus
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Symbol: Ppib
Name: peptidylprolyl isomerase B
RGD ID: 620312
Description: Predicted to have RNA polymerase binding activity; cyclosporin A binding activity; and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in several processes, including neutrophil chemotaxis; positive regulation by host of viral genome replication; and protein stabilization. Localizes to smooth endoplasmic reticulum. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 9. Orthologous to human PPIB (peptidylprolyl isomerase B); PARTICIPATES IN codeine and morphine pharmacodynamics pathway; codeine and morphine pharmacokinetics pathway; etoposide pharmacodynamics pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cyclophilin B; CYP-S1; CypB; peptidyl-prolyl cis-trans isomerase B; PPIase; PPIase B; rotamase; rotamase B; S-cyclophilin; S-cyclophylin; Scylp
Orthologs:
Homo sapiens (human) : PPIB (peptidylprolyl isomerase B)  HGNC  Alliance
Mus musculus (house mouse) : Ppib (peptidylprolyl isomerase B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppib (peptidylprolyl isomerase B)
Pan paniscus (bonobo/pygmy chimpanzee) : PPIB (peptidylprolyl isomerase B)
Canis lupus familiaris (dog) : PPIB (peptidylprolyl isomerase B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppib (peptidylprolyl isomerase B)
Sus scrofa (pig) : PPIB (peptidylprolyl isomerase B)
Chlorocebus sabaeus (African green monkey) : PPIB (peptidylprolyl isomerase B)
Heterocephalus glaber (naked mole-rat) : Ppib (peptidylprolyl isomerase B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0871,719,681 - 71,725,538 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl871,719,563 - 71,725,562 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0871,388,620 - 71,394,477 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4870,343,463 - 70,349,320 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1870,362,516 - 70,368,374 (+)NCBI
Celera865,993,837 - 65,999,694 (+)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ppib
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620312
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.