Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Csk (C-terminal Src kinase) Rattus norvegicus
Analyze
Symbol: Csk
Name: C-terminal Src kinase
Description: Exhibits proline-rich region binding activity; protein phosphatase binding activity; and protein tyrosine kinase activity. Involved in several processes, including central nervous system development; negative regulation of bone resorption; and regulation of phosphorylation. Localizes to the cytoplasm and membrane raft. Biomarker of hepatocellular carcinoma. Orthologous to human CSK (C-terminal Src kinase); PARTICIPATES IN platelet-derived growth factor signaling pathway; chemokine mediated signaling pathway; neurotrophic factor signaling pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dibromophenyl 2,4,5-tribromophenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: C-SRC kinase; c-src tyrosine kinase; CSK, non-receptor tyrosine kinase; LOC315707; MGC112926; protein-tyrosine kinase (CSK); tyrosine-protein kinase CSK
Orthologs:
Homo sapiens (human) : CSK (C-terminal Src kinase)  HGNC  Alliance
Mus musculus (house mouse) : Csk (c-src tyrosine kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Csk (C-terminal Src kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : CSK (C-terminal Src kinase)
Canis lupus familiaris (dog) : CSK (C-terminal Src kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Csk (C-terminal Src kinase)
Sus scrofa (pig) : CSK (CSK, non-receptor tyrosine kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0862,405,714 - 62,424,707 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0862,183,286 - 62,208,785 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4861,381,336 - 61,386,013 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1861,400,389 - 61,405,067 (-)NCBI
Celera857,495,667 - 57,500,290 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Csk
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308800
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.