CYP2E1 (cytochrome P450 family 2 subfamily E member 1) - Rat Genome Database
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Gene: CYP2E1 (cytochrome P450 family 2 subfamily E member 1) Homo sapiens
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Symbol: CYP2E1
Name: cytochrome P450 family 2 subfamily E member 1
RGD ID: 1345007
HGNC Page HGNC
Description: Exhibits 4-nitrophenol 2-monooxygenase activity; enzyme binding activity; and heme binding activity. Involved in several processes, including 4-nitrophenol metabolic process; lipid hydroxylation; and monoterpenoid metabolic process. Predicted to localize to endoplasmic reticulum and mitochondrial inner membrane. Implicated in several diseases, including acoustic neuroma; fatty liver disease; gastrointestinal system cancer (multiple); liver disease (multiple); and lung disease (multiple). Biomarker of alcohol use disorder; asthma; diabetes mellitus (multiple); interstitial lung disease (multiple); and morbid obesity.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 4-nitrophenol 2-hydroxylase; CPE1; CYP2E; CYPIIE1; cytochrome P450 2E1; cytochrome P450, family 2, subfamily E, polypeptide 1; cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1; cytochrome P450-J; flavoprotein-linked monooxygenase; microsomal monooxygenase; P450-J; P450C2E; xenobiotic monooxygenase
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl10133,520,406 - 133,561,220 (+)EnsemblGRCh38hg38GRCh38
GRCh3810133,527,363 - 133,539,123 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710135,340,867 - 135,352,627 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh3710135,340,300 - 135,352,627 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610135,190,857 - 135,202,610 (+)NCBINCBI36hg18NCBI36
Build 3410135,229,747 - 135,241,501NCBI
Celera10128,168,529 - 128,180,282 (-)NCBI
Cytogenetic Map10q26.3NCBI
HuRef10128,882,691 - 128,894,624 (+)NCBIHuRef
CHM1_110135,620,490 - 135,632,188 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acoustic neuroma  (IAGP)
acute kidney failure  (ISO)
acute lymphoblastic leukemia  (EXP)
adenocarcinoma  (EXP)
alcohol use disorder  (EXP,IEP,ISO)
Alcoholic Fatty Liver  (EXP,ISO)
alcoholic liver cirrhosis  (EXP,IMP)
Alcoholic Liver Diseases  (IEP,ISO)
amenorrhea  (IAGP)
asbestosis  (IEP)
asthma  (EXP,IEP,ISO)
Binge Drinking  (IDA,ISO)
Cardiomegaly  (EXP)
Chemical and Drug Induced Liver Injury  (EXP,IAGP,IMP,ISO)
Chronic Bronchitis  (IAGP)
chronic obstructive pulmonary disease  (IAGP)
colon cancer  (ISO)
colorectal cancer  (IAGP)
Drug Eruptions  (EXP)
drug-induced hepatitis  (ISO)
Drug-Related Side Effects and Adverse Reactions  (EXP)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Neoplasms  (EXP)
extrinsic allergic alveolitis  (IEP)
familial hyperlipidemia  (ISO)
fatty liver disease  (EXP,IAGP,ISO)
hepatocellular adenoma  (ISO)
hepatocellular carcinoma  (EXP,IAGP)
high grade glioma  (IAGP)
Human Viral Hepatitis  (IAGP)
intrahepatic cholestasis  (ISO)
liver disease  (IAGP,ISO)
Liver Injury  (ISO)
Liver Neoplasms  (EXP)
lung disease  (ISO)
Lung Neoplasms  (EXP)
lung non-small cell carcinoma  (EXP)
mental depression  (ISO)
Micronuclei, Chromosome-Defective  (EXP)
middle cerebral artery infarction  (ISO)
morbid obesity  (IEP)
nasopharynx carcinoma  (IAGP)
Necrosis  (EXP)
Neoplasm Invasiveness  (EXP)
non-alcoholic fatty liver disease  (EXP,ISO)
non-Hodgkin lymphoma  (EXP)
obesity  (EXP,ISO)
oral cavity cancer  (IAGP)
oral squamous cell carcinoma  (IAGP)
Parkinson's disease  (EXP)
Patent Ductus Venosus  (ISO)
pneumonia  (IAGP,ISO)
Prostatic Neoplasms  (EXP)
Reperfusion Injury  (ISO)
Sepsis  (ISO)
stomach cancer  (IAGP)
Testicular Injury  (ISO)
type 1 diabetes mellitus  (IEP)
type 2 diabetes mellitus  (IEP,ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-alpha-tocopherol  (EXP,ISO)
(+)-artemisinin  (ISO)
(+)-catechin  (EXP,ISO)
(+)-epicatechin-3-O-gallate  (ISO)
(+)-schisandrin B  (ISO)
(+)-taxifolin  (EXP)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(-)-trans-epsilon-viniferin  (EXP)
(R)-carnitine  (ISO)
(R)-lipoic acid  (ISO)
(S)-mandelic acid  (EXP)
(S)-nicotine  (ISO)
1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane  (EXP)
1,1,1-trichloroethane  (EXP)
1,1-Dichloroethane  (ISO)
1,1-dichloroethene  (EXP,ISO)
1,2,3,5-tetrachlorobenzene  (EXP)
1,2,4,5-tetrachlorobenzene  (ISO)
1,2,4-trichlorobenzene  (EXP)
1,2-dibromoethane  (EXP)
1,2-dichlorobenzene  (EXP,ISO)
1,2-dichloroethane  (EXP,ISO)
1,2-dichloroethene  (EXP,ISO)
1,2-dimethylhydrazine  (ISO)
1,4-benzoquinone  (ISO)
1,4-dichlorobenzene  (EXP,ISO)
1,4-dioxane  (ISO)
1,4-naphthoquinone  (EXP)
1-benzylpiperazine  (ISO)
1-bromopropane  (ISO)
1-naphthol  (EXP)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (EXP,ISO)
19(S)-HETE  (ISO)
19-HETE  (ISO)
1H-imidazole  (ISO)
1H-pyrazole  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',4,5-tetrachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,5,6-tetrachlorophenol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,6-dimethylaniline  (EXP)
2,6-dimethylnaphthalene  (EXP)
2-acetamidofluorene  (ISO)
2-amino-2-deoxy-D-galactopyranose  (ISO)
2-chloroethanol  (ISO)
2-naphthol  (EXP)
2-nitroanisole  (EXP,ISO)
2-nitrophenol  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3,4-dihydroxybenzoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-(Methylthio)-1-propene  (ISO)
3-methylcholanthrene  (EXP,ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP,ISO)
4-methylumbelliferone  (ISO)
4-nitrocatechol  (EXP,ISO)
4-nitrophenol  (EXP,ISO)
4-Vinylcyclohexene  (ISO)
4-vinylcyclohexene dioxide  (ISO)
5-(2-chloroethyl)-4-methylthiazole  (EXP,ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
5-methoxy-N,N-diisopropyltryptamine  (EXP)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (EXP)
7,12-dimethyltetraphene  (ISO)
7-ethoxycoumarin  (EXP)
8-Br-cAMP  (EXP)
abamectin  (ISO)
acarbose  (ISO)
acephate  (ISO)
acetaldehyde  (EXP,ISO)
acetamide  (ISO)
acetic acid  (EXP)
acetone  (EXP,ISO)
acetonitrile  (EXP,ISO)
acetylsalicylic acid  (ISO)
acrylamide  (EXP,ISO)
acrylonitrile  (EXP,ISO)
acteoside  (ISO)
aflatoxin B1  (EXP,ISO)
alcohol  (EXP,ISO)
alizarin  (EXP)
alkaloid  (ISO)
all-trans-retinoic acid  (EXP,ISO)
allethrin  (ISO)
allyl alcohol  (ISO)
alpha-hexachlorocyclohexane  (ISO)
alpha-linolenic acid  (EXP)
alpha-methyltryptamine  (EXP)
amiodarone  (EXP)
amitraz  (ISO)
amitrole  (EXP)
ammonium chloride  (ISO)
amodiaquine  (EXP)
amphibole asbestos  (EXP)
ampicillin  (ISO)
angelicin  (ISO)
aniline  (EXP,ISO)
anthocyanin  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
apigenin  (EXP,ISO)
arachidonic acid  (EXP,ISO)
arecoline  (ISO)
Aroclor 1254  (EXP,ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenous acid  (EXP)
asiatic acid  (ISO)
aspartame  (ISO)
atrazine  (ISO)
baicalein  (EXP)
benzene  (EXP,ISO)
benzene-1,2,4-triol  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
benzylideneacetone  (ISO)
berberine  (ISO)
Besigomsin  (ISO)
beta-carboline  (EXP)
beta-naphthoflavone  (EXP,ISO)
bifenthrin  (ISO)
bilobalide  (ISO)
biotin  (EXP)
biphenyl-4-amine  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
Bromadiolone  (ISO)
bromobenzene  (ISO)
bromodichloromethane  (EXP,ISO)
bromoethene  (EXP)
brucine  (ISO)
bucladesine  (EXP)
buta-1,3-diene  (EXP,ISO)
butan-2-one  (EXP)
butane-1,3-diol  (ISO)
Butylbenzyl phthalate  (ISO)
Butylparaben  (ISO)
C60 fullerene  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
cafestol  (ISO)
caffeine  (EXP)
calcium atom  (EXP,ISO)
calcium(0)  (EXP,ISO)
canadine  (ISO)
capsaicin  (ISO)
carbamazepine  (ISO)
carbaryl  (EXP)
carbon monoxide  (EXP,ISO)
carbon nanotube  (ISO)
carnosine  (ISO)
catechol  (EXP,ISO)
chenodeoxycholic acid  (EXP)
CHIR 99021  (EXP)
chloral hydrate  (ISO)
chlorfluazuron  (EXP)
chlorobenzene  (EXP,ISO)
chloroethene  (EXP,ISO)
chloroform  (EXP)
chlorogenic acid  (ISO)
chloromethane  (EXP)
chloroprene  (ISO)
chlorpromazine  (EXP)
chlorpyrifos  (EXP)
chlorzoxazone  (EXP,ISO)
cholesterol  (ISO)
choline  (ISO)
chrysene  (ISO)
ciguatoxin CTX1B  (ISO)
cimetidine  (EXP)
cinnamic acid  (EXP)
ciprofibrate  (ISO)
cis-caffeic acid  (ISO)
cisplatin  (ISO)
citral  (EXP)
clofibrate  (ISO)
clothianidin  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
cortisol  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
crocin-1  (ISO)
curcumin  (EXP,ISO)
cyanides  (ISO)
cyanocob(III)alamin  (ISO)
cyclohexanols  (ISO)
cycloheximide  (EXP,ISO)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
cyfluthrin  (ISO)
cyhalothrin  (ISO)
cylindrospermopsin  (ISO)
cypermethrin  (EXP,ISO)
cyproconazole  (EXP,ISO)
D-penicillamine  (EXP)
daidzein  (ISO)
deoxycholic acid  (ISO)
desferrioxamine B  (ISO)
desipramine  (EXP)
dexamethasone  (ISO)
dextran sulfate  (ISO)
dextromethorphan  (ISO)
diallyl disulfide  (EXP,ISO)
Diallyl sulfide  (EXP,ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (EXP)
dibenz[a,h]anthracene  (EXP)
dibenziodolium  (ISO)
dibutyl phthalate  (ISO)
dichloromethane  (EXP,ISO)
diclofenac  (EXP)
dicofol  (ISO)
dicoumarol  (EXP,ISO)
diepoxybutane  (EXP)
diethyldithiocarbamic acid  (EXP,ISO)
diethylstilbestrol  (ISO)
dihydrocapsaicin  (ISO)
dimethyl sulfoxide  (EXP,ISO)
dimethylmercury  (ISO)
dioscin  (ISO)
diosmetin  (EXP)
diosmin  (ISO)
dioxygen  (EXP,ISO)
dipropyl disulfide  (EXP)
dipropyl phthalate  (ISO)
diprotium oxide  (ISO)
disulfiram  (EXP,ISO)
dodecanoic acid  (EXP)
dopamine  (ISO)
doxorubicin  (ISO)
dronedarone  (EXP)
ebselen  (ISO)
elemental selenium  (ISO)
ellipticine  (EXP)
emamectin benzoate  (ISO)
endosulfan  (EXP,ISO)
enfuvirtide  (EXP)
enilconazole  (EXP)
epoxiconazole  (ISO)
Erionite  (ISO)
Estragole  (EXP)
ethambutol  (EXP,ISO)
ethanol  (EXP,ISO)
ethene  (ISO)
ethosuximide  (ISO)
ethyl methanesulfonate  (EXP)
ethylbenzene  (ISO)
ethylene glycol bis(2-aminoethyl)tetraacetic acid  (EXP)
ethylenediaminetetraacetic acid  (EXP)
ethylparaben  (ISO)
eugenol  (EXP,ISO)
farnesol  (EXP,ISO)
felbamate  (ISO)
fenarimol  (ISO)
fenitrothion  (EXP)
fenofibrate  (ISO)
fenvalerate  (EXP)
fipronil  (EXP,ISO)
flavonoids  (ISO)
fluoranthene  (EXP)
fluoroethene  (EXP,ISO)
fluphenazine  (EXP)
folic acid  (ISO)
fomepizole  (EXP,ISO)
fructose  (ISO)
fulvestrant  (EXP)
fumaraldehyde  (ISO)
fumonisin B1  (ISO)
Furafylline  (ISO)
furan  (ISO)
gabapentin  (ISO)
gadolinium trichloride  (ISO)
gallocatechin  (ISO)
gamma-hexachlorocyclohexane  (EXP,ISO)
genistein  (ISO)
gentamycin  (ISO)
geranial  (EXP)
geraniol  (EXP,ISO)
ginsenoside Rg1  (ISO)
glafenine  (ISO)
glutathione  (EXP,ISO)
glycerol  (EXP)
glycine betaine  (EXP,ISO)
glycyrrhetinate  (ISO)
glycyrrhetinic acid  (ISO)
glyphosate  (ISO)
GW 4064  (EXP)
halothane  (EXP,ISO)
hemin  (EXP,ISO)
hesperetin  (ISO)
hexachlorobenzene  (ISO)
hexadecanoic acid  (ISO)
hexane  (EXP,ISO)
hydrazine  (ISO)
hydrogen peroxide  (EXP)
hydroquinone  (EXP,ISO)
Hypaconitine  (EXP)
imidazoles  (ISO)
indole-3-methanol  (EXP)
indometacin  (ISO)
irbesartan  (ISO)
iron(III) citrate  (EXP)
iron(III) nitrilotriacetate  (EXP)
isatin  (EXP)
isobavachalcone  (ISO)
isobutyronitrile  (ISO)
isoliquiritigenin  (ISO)
isoniazide  (EXP,ISO)
isoprenaline  (ISO)
isoproturon  (EXP)
isoquinolines  (ISO)
ivermectin  (ISO)
kaempferol  (ISO)
kahweol  (ISO)
kalopanaxsaponin A  (ISO)
ketamine  (ISO)
ketoconazole  (EXP)
kojic acid  (ISO)
L-ascorbic acid  (EXP,ISO)
L-methionine  (ISO)
lamotrigine  (EXP)
Lasiocarpine  (EXP)
leupeptin  (EXP)
linoleic acid  (EXP)
lipoic acid  (ISO)
lipopolysaccharide  (EXP,ISO)
liquiritin  (ISO)
lithocholic acid  (ISO)
luteolin  (ISO)
LY 364947  (ISO)
LY294002  (ISO)
lycopene  (ISO)
m-tolualdehyde  (ISO)
m-xylene  (EXP,ISO)
malathion  (EXP)
mancozeb  (EXP)
mandelic acid  (EXP)
maneb  (ISO)
mangiferin  (ISO)
melatonin  (ISO)
menadione  (EXP,ISO)
mephenytoin  (ISO)
mercury dichloride  (ISO)
metformin  (ISO)
methamphetamine  (EXP)
methapyrilene  (EXP,ISO)
methoxsalen  (ISO)
methoxychlor  (ISO)
methoxyflurane  (EXP)
methyltestosterone  (EXP)
metronidazole  (ISO)
microcystin-LR  (ISO)
midazolam  (EXP)
mirex  (ISO)
Monobutylphthalate  (ISO)
monocrotophos  (EXP,ISO)
monosodium L-glutamate  (ISO)
muconic acid  (EXP)
myricetin  (EXP)
myricitrin  (ISO)
N'-(2,4-dimethylphenyl)-N-methylformamidine  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N,N-diisopropyltryptamine  (EXP)
N,N-dimethylformamide  (EXP,ISO)
N-acetyl-1,4-benzoquinone imine  (EXP,ISO)
N-acetyl-L-cysteine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methylformamide  (EXP,ISO)
N-Nitrosodi-n-butylamine  (EXP)
N-Nitrosodi-n-propylamine  (EXP)
N-Nitrosodiethanolamine  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP,ISO)
N-Nitrosomethylethylamine  (EXP)
N-nitrosomorpholine  (EXP)
N-nitrosopiperidine  (EXP)
N-Nitrosopyrrolidine  (EXP)
NADP zwitterion  (EXP,ISO)
NADP(+)  (EXP,ISO)
naphthalene  (EXP)
nefazodone  (ISO)
neobavaisoflavone  (ISO)
neomycin  (ISO)
nicotinamide  (ISO)
nicotine  (ISO)
nifedipine  (ISO)
nitric oxide  (EXP)
nitroglycerin  (ISO)
Notopterol  (EXP)
o-anisidine  (EXP)
O-methyleugenol  (EXP)
o-xylene  (EXP,ISO)
obeticholic acid  (EXP)
ochratoxin A  (EXP)
octadecanoic acid  (EXP)
okadaic acid  (ISO)
oleanolic acid  (ISO)
oleic acid  (EXP,ISO)
oltipraz  (EXP)
omeprazole  (EXP)
orphenadrine  (EXP)
oxirane  (ISO)
oxycodone  (ISO)
ozone  (ISO)
p-cresol  (EXP)
p-xylene  (EXP)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
parathion  (EXP)
pentachlorobenzene  (EXP,ISO)
pentachlorophenol  (EXP)
perfluorononanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
phenacetin  (ISO)
phenanthrene  (EXP,ISO)
phenethyl caffeate  (ISO)
phenethyl isothiocyanate  (EXP,ISO)
phenformin  (ISO)
phenobarbital  (ISO)
phenol  (EXP,ISO)
phenthoate  (EXP)
phenylglyoxylic acid  (EXP)
phenytoin  (EXP,ISO)
PhIP  (EXP)
phorbol 13-acetate 12-myristate  (EXP)
phthalaldehyde  (ISO)
pioglitazone  (ISO)
piperidin-2-one  (ISO)
Pipermethystine  (ISO)
potassium dichromate  (ISO)
primaquine  (EXP)
prochloraz  (EXP)
procymidone  (ISO)
profenofos  (EXP)
progesterone  (ISO)
prop-2-yn-1-ol  (ISO)
propacetamol  (ISO)
propan-2-ol  (ISO)
propetamphos  (ISO)
propiconazole  (ISO)
propylparaben  (ISO)
psoralen  (ISO)
psoralidin  (ISO)
puerarin  (ISO)
purpurin  (EXP)
purpurogallin  (ISO)
pyrazinecarboxamide  (ISO)
pyrazines  (ISO)
pyrene  (ISO)
pyridine  (EXP,ISO)
pyridine N-oxide  (ISO)
pyridines  (ISO)
pyrogallol  (ISO)
quartz  (ISO)
quercetin  (EXP,ISO)
quercetin 3-O-beta-D-galactopyranoside  (ISO)
quinacrine  (ISO)
quinidine  (ISO)
quinoline  (EXP,ISO)
quinolines  (ISO)
rac-1,2-dichloropropane  (EXP)
reactive oxygen species  (EXP,ISO)
resveratrol  (ISO)
retinyl acetate  (ISO)
Retrorsine  (ISO)
riddelliine  (ISO)
rifampicin  (EXP,ISO)
rotenone  (ISO)
S-adenosyl-L-methioninate  (EXP,ISO)
S-adenosyl-L-methionine  (EXP,ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
safrole  (EXP)
salvianolic acid B  (ISO)
satraplatin  (EXP)
SB 203580  (EXP)
selenium atom  (ISO)
senecionine  (EXP,ISO)
sevoflurane  (EXP)
Shikonin  (EXP,ISO)
silicon dioxide  (ISO)
skatole  (EXP)
sodium arsenite  (EXP,ISO)
sodium chromate  (ISO)
staurosporine  (ISO)
streptozocin  (ISO)
styrene  (EXP,ISO)
styrene oxide  (EXP)
Sudan I  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
taurine  (ISO)
tebuconazole  (EXP,ISO)
tenofovir disoproxil fumarate  (EXP)
tert-butyl ethyl ether  (ISO)
testosterone  (ISO)
Tetrachlorobisphenol A  (EXP)
tetrachloroethene  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
tetrachlorophenol  (EXP)
tetracycline  (ISO)
tetrahydrocurcumin  (ISO)
tetraphene  (ISO)
thallium  (ISO)
theobromine  (EXP)
theophylline  (EXP,ISO)
thiacloprid  (EXP)
thiamine(1+) chloride  (ISO)
thiazoles  (ISO)
thioacetamide  (ISO)
thiophanate-methyl  (ISO)
thioridazine  (EXP)
thiostrepton  (EXP)
thiram  (ISO)
Tiopronin  (ISO)
tirapazamine  (ISO)
titanium dioxide  (ISO)
toluene  (EXP,ISO)
trabectedin  (ISO)
trans-1,2-dichloroethene  (EXP,ISO)
trans-caffeic acid  (ISO)
trans-cinnamic acid  (EXP)
transfluthrin  (ISO)
tranylcypromine  (EXP)
triadimefon  (ISO)
trichloroacetic acid  (EXP)
trichloroethene  (EXP,ISO)
troglitazone  (ISO)
tryptamines  (EXP)
umbelliferone  (ISO)
uranium atom  (ISO)
urethane  (EXP,ISO)
ursodeoxycholic acid  (ISO)
usnic acid  (EXP)
valproic acid  (EXP,ISO)
vancomycin  (ISO)
vanoxerine dihydrochloride  (EXP)
vinclozolin  (ISO)
vinyl carbamate  (EXP,ISO)
vitamin E  (EXP,ISO)
water  (ISO)
wortmannin  (EXP,ISO)
Wuweizisu C  (ISO)
XL147  (ISO)
zearalenone  (ISO)
zinc atom  (ISO)
zinc protoporphyrin  (EXP,ISO)
zinc sulfate  (EXP,ISO)
zinc(0)  (ISO)
zingerone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
acetylsalicylic acid pharmacodynamics pathway  (EXP)
antipyrine drug pathway  (EXP)
arachidonic acid metabolic pathway  (EXP,IEA)
caffeine pharmacokinetics pathway  (EXP)
celecoxib pharmacodynamics pathway  (EXP)
diclofenac pharmacodynamics pathway  (EXP)
diflunisal pharmacodynamics pathway  (EXP)
disulfiram pharmacodynamics pathway  (EXP)
etodolac pharmacodynamics pathway  (EXP)
felbamate pharmacokinetics pathway  (EXP)
fenoprofen pharmacodynamics pathway  (EXP)
flurbiprofen pharmacodynamics pathway  (EXP)
ibuprofen pharmacodynamics pathway  (EXP)
indometacin pharmacodynamics pathway  (EXP)
indometacin pharmacodynamics pathway  (EXP)
ketoprofen pharmacodynamics pathway  (EXP)
ketorolac pharmacodynamics pathway  (EXP)
leukotriene C4 synthase deficiency pathway  (EXP)
linoleic acid metabolic pathway  (IEA)
lornoxicam pharmacodynamics pathway  (EXP)
magnesium salicylate pharmacodynamics pathway  (EXP)
mefenamic acid pharmacodynamics pathway  (EXP)
meloxicam pharmacodynamics pathway  (EXP)
nabumetone pharmacodynamics pathway  (EXP)
naproxen pharmacodynamics pathway  (EXP)
paracetamol drug pathway  (EXP)
paracetamol pharmacokinetics pathway  (EXP,ISO)
paracetamol response pathway  (TAS)
phenytoin pharmacodynamics pathway  (EXP)
piroxicam pharmacodynamics pathway  (EXP)
salicylic acid pharmacodynamics pathway  (EXP)
sodium salicylate pharmacodynamics pathway  (EXP)
sulindac pharmacodynamics pathway  (EXP)
tenoxicam pharmacodynamics pathway  (EXP)
tiaprofenic acid pharmacodynamics pathway  (EXP)
tolmetin pharmacodynamics pathway  (EXP)
valdecoxib pharmacodynamics pathway  (EXP)

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
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