(+)-alpha-tocopherol multiple interactions ISO RGD:2475 6480464 [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein] more ... CTD PMID:26332274 , PMID:27919644 (+)-alpha-tocopherol increases expression EXP 6480464 alpha-Tocopherol results in increased expression of CYP2E1 mRNA CTD PMID:28062356 (+)-alpha-tocopherol increases expression ISO RGD:2475 6480464 alpha-Tocopherol results in increased expression of CYP2E1 mRNA CTD PMID:26332274 (+)-artemisinin increases expression ISO RGD:10451 6480464 artemisinine results in increased expression of CYP2E1 mRNA CTD PMID:17962186 (+)-catechin multiple interactions EXP 6480464 [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of CYP2E1 mRNA, Catechin inhibits the reaction [Ethanol results in increased expression of CYP2E1] CTD PMID:21352821 , PMID:24763279 (+)-schisandrin B decreases activity ISO RGD:10451 6480464 schizandrin B results in decreased activity of CYP2E1 protein CTD PMID:25753323 (+)-schisandrin B multiple interactions ISO RGD:2475 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA] CTD PMID:31150632 (+)-taxifolin decreases expression EXP 6480464 taxifolin results in decreased expression of CYP2E1 mRNA CTD PMID:17541156 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:10451 6480464 epigallocatechin gallate results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:14600287 (-)-epigallocatechin 3-gallate multiple interactions EXP 6480464 epigallocatechin gallate inhibits the reaction [Acrylamide results in increased expression of CYP2E1 protein] CTD PMID:24508477 (-)-epigallocatechin 3-gallate affects binding ISO RGD:2475 6480464 epigallocatechin gallate binds to CYP2E1 protein CTD PMID:23010222 (-)-trans-epsilon-viniferin decreases activity EXP 6480464 epsilon-viniferin results in decreased activity of CYP2E1 protein CTD PMID:12818727 (R)-carnitine multiple interactions ISO RGD:2475 6480464 Carnitine promotes the reaction [Ethanol results in increased expression of CYP2E1 protein] CTD PMID:8130774 (S)-mandelic acid multiple interactions EXP 6480464 CYP2E1 polymorphism affects the metabolism of [mandelic acid co-treated with phenylglyoxylic acid] CTD PMID:25562543 (S)-nicotine increases expression ISO RGD:2475 6480464 Nicotine results in increased expression of CYP2E1 protein CTD PMID:16434548 1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane increases hydroxylation EXP 6480464 CYP2E1 protein results in increased hydroxylation of 1 more ... CTD PMID:9047321 1,1,1-trichloroethane increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of 1 more ... CTD PMID:1664256 1,1-Dichloroethane multiple interactions ISO RGD:2475 6480464 1, 1-dichloroethane results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:11606809 1,1-Dichloroethane increases expression ISO RGD:2475 6480464 1, 1-dichloroethane results in increased expression of CYP2E1 protein CTD PMID:11606809 1,1-Dichloroethane increases activity ISO RGD:2475 6480464 1, 1-dichloroethane results in increased activity of CYP2E1 protein CTD PMID:11606809 1,1-dichloroethene multiple interactions EXP 6480464 diallyl sulfone inhibits the reaction [CYP2E1 protein results in increased metabolism of vinylidene chloride] CTD PMID:10215634 1,1-dichloroethene increases expression ISO RGD:10451 6480464 vinylidene chloride results in increased expression of CYP2E1 protein CTD PMID:26682919 1,1-dichloroethene increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of vinylidene chloride CTD PMID:10215634 , PMID:15319346 1,1-dichloroethene increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of vinylidene chloride CTD PMID:11356946 , PMID:15319346 1,1-dichloroethene increases metabolic processing ISO RGD:2475 6480464 CYP2E1 protein results in increased metabolism of vinylidene chloride CTD PMID:15319346 1,2,3,5-tetrachlorobenzene increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of 1 more ... CTD PMID:7747284 1,2,3,5-tetrachlorobenzene increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of 1 more ... CTD PMID:7747284 1,2,4,5-tetrachlorobenzene increases expression ISO RGD:2475 6480464 1 more ... CTD PMID:10696772 1,2,4-trichlorobenzene increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of 1 more ... CTD PMID:7747284 1,2,4-trichlorobenzene increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of 1 more ... CTD PMID:7747284 1,2-dibromoethane increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Ethylene Dibromide CTD PMID:10841534 , PMID:18350910 1,2-dibromoethane increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of Ethylene Dibromide CTD PMID:1664256 1,2-dichlorobenzene increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of 2-dichlorobenzene CTD PMID:7747284 , PMID:9817075 1,2-dichlorobenzene increases oxidation ISO RGD:2475 6480464 CYP2E1 protein results in increased oxidation of 2-dichlorobenzene CTD PMID:9817075 1,2-dichlorobenzene multiple interactions ISO RGD:2475 6480464 [2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP2E1 protein more ... CTD PMID:24713513 , PMID:9817075 1,2-dichlorobenzene multiple interactions ISO RGD:10451 6480464 [Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene, dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene] CTD PMID:9817075 1,2-dichlorobenzene increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of 2-dichlorobenzene CTD PMID:7747284 1,2-dichloroethane increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of ethylene dichloride CTD PMID:1664256 1,2-dichloroethane increases expression ISO RGD:10451 6480464 ethylene dichloride results in increased expression of CYP2E1 mRNA, ethylene dichloride results in increased expression of CYP2E1 protein CTD PMID:27301210 more ... 1,2-dichloroethane multiple interactions ISO RGD:10451 6480464 [ethylene dichloride co-treated with Ethanol] results in increased expression of CYP2E1 protein more ... CTD PMID:27301210 , PMID:30664321 1,2-dichloroethene decreases expression ISO RGD:2475 6480464 1, 2-dichloroethylene results in decreased expression of CYP2E1 protein CTD PMID:9671540 1,2-dichloroethene multiple interactions ISO RGD:10451 6480464 1 more ... CTD PMID:10828257 1,2-dichloroethene multiple interactions ISO RGD:2475 6480464 1 more ... CTD PMID:7871537 , PMID:9851676 1,2-dichloroethene decreases activity ISO RGD:2475 6480464 1, 2-dichloroethylene results in decreased activity of CYP2E1 protein CTD PMID:15205388 more ... 1,2-dimethylhydrazine multiple interactions ISO RGD:2475 6480464 asiatic acid inhibits the reaction [1 more ... CTD PMID:19497424 more ... 1,2-dimethylhydrazine increases expression ISO RGD:2475 6480464 1, 2-Dimethylhydrazine results in increased expression of CYP2E1 protein CTD PMID:30720227 1,2-dimethylhydrazine increases activity ISO RGD:2475 6480464 1, 2-Dimethylhydrazine results in increased activity of CYP2E1 protein CTD PMID:19497424 , PMID:29108773 1,4-benzoquinone decreases expression ISO RGD:2475 6480464 quinone results in decreased expression of CYP2E1 protein CTD PMID:10462055 1,4-dichlorobenzene increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of 4-dichlorobenzene CTD PMID:7747284 1,4-dichlorobenzene multiple interactions ISO RGD:2475 6480464 [Isoniazid results in increased activity of CYP2E1 protein] which results in increased metabolism of 4-dichlorobenzene CTD PMID:9051121 1,4-dichlorobenzene increases expression ISO RGD:2475 6480464 4-dichlorobenzene results in increased expression of CYP2E1 protein CTD PMID:10696772 1,4-dichlorobenzene increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of 4-dichlorobenzene CTD PMID:7747284 , PMID:9817075 1,4-dioxane multiple interactions ISO RGD:2475 6480464 1, 4-dioxane results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:15490126 1,4-dioxane increases expression ISO RGD:2475 6480464 1, 4-dioxane results in increased expression of CYP2E1 mRNA CTD PMID:15490126 1,4-dioxane increases activity ISO RGD:2475 6480464 1, 4-dioxane results in increased activity of CYP2E1 protein CTD PMID:15490126 1,4-naphthoquinone increases abundance EXP 6480464 CYP2E1 protein results in increased abundance of 1, 4-naphthoquinone CTD PMID:16243959 1-benzylpiperazine decreases expression ISO RGD:2475 6480464 N-benzylpiperazine results in decreased expression of CYP2E1 mRNA CTD PMID:26821219 1-bromopropane increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to 1-bromopropane CTD PMID:19638432 1-bromopropane increases expression ISO RGD:2475 6480464 1-bromopropane results in increased expression of CYP2E1 CTD PMID:30247689 1-bromopropane multiple interactions ISO RGD:2475 6480464 allyl sulfide inhibits the reaction [1-bromopropane results in increased expression of CYP2E1] CTD PMID:30247689 1-naphthol increases abundance EXP 6480464 CYP2E1 protein results in increased abundance of 1-naphthol CTD PMID:16243959 1-naphthyl isothiocyanate decreases expression ISO RGD:10451 6480464 1-Naphthylisothiocyanate results in decreased expression of CYP2E1 mRNA CTD PMID:15913567 1-naphthyl isothiocyanate decreases expression ISO RGD:2475 6480464 1-Naphthylisothiocyanate results in decreased expression of CYP2E1 mRNA CTD PMID:30723492 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of CYP2E1 mRNA CTD PMID:20106945 17beta-estradiol multiple interactions ISO RGD:2475 6480464 [Estradiol co-treated with Plant Preparations] results in decreased expression of CYP2E1 mRNA CTD PMID:26945725 17beta-estradiol decreases expression ISO RGD:10451 6480464 Estradiol results in decreased expression of CYP2E1 mRNA CTD PMID:19484750 17beta-estradiol increases activity EXP 6480464 Estradiol results in increased activity of CYP2E1 protein CTD PMID:22837389 19(S)-HETE affects metabolic processing ISO RGD:2475 6480464 CYP2E1 protein affects the metabolism of 19-hydroxy-5 more ... CTD PMID:15205388 19-HETE affects metabolic processing ISO RGD:2475 6480464 CYP2E1 protein affects the metabolism of 19-hydroxy-5 more ... CTD PMID:15205388 1H-imidazole increases expression ISO RGD:2475 6480464 imidazole results in increased expression of CYP2E1 protein CTD PMID:3337723 1H-pyrazole increases expression EXP 6480464 pyrazole results in increased expression of CYP2E1 protein CTD PMID:8074729 1H-pyrazole increases expression ISO RGD:2475 6480464 pyrazole results in increased expression of CYP2E1 protein CTD PMID:3113478 more ... 1H-pyrazole increases activity ISO RGD:2475 6480464 pyrazole results in increased activity of CYP2E1 protein CTD PMID:3782137 , PMID:8734847 1H-pyrazole affects expression ISO RGD:10451 6480464 pyrazole affects the expression of CYP2E1 protein CTD PMID:19679878 1H-pyrazole increases expression ISO RGD:10451 6480464 pyrazole results in increased expression of CYP2E1 protein CTD PMID:9698299 2,2',4,4'-Tetrabromodiphenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:26808241 2,2',4,5-tetrachlorobiphenyl multiple interactions EXP 6480464 [[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 2 more ... CTD PMID:27913846 2,2',5,5'-tetrachlorobiphenyl multiple interactions EXP 6480464 [[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 2 more ... CTD PMID:27913846 2,3,5,6-tetrachlorophenol increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of 2 more ... CTD PMID:7747284 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:10451 6480464 Tetrachlorodibenzodioxin affects the expression of CYP2E1 mRNA CTD PMID:17949056 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10451 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP2E1 gene] CTD PMID:28213091 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 mRNA] more ... CTD PMID:26159488 , PMID:28673560 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 more ... CTD PMID:20106945 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of CYP2E1 mRNA CTD PMID:23669205 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:2475 6480464 Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 mRNA, Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 protein CTD PMID:16054898 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of CYP2E1 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:10451 6480464 Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 mRNA CTD PMID:19770486 , PMID:28213091 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:10451 6480464 Tetrachlorodibenzodioxin results in increased expression of CYP2E1 mRNA CTD PMID:16120747 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:2475 6480464 Tetrachlorodibenzodioxin results in increased expression of CYP2E1 mRNA CTD PMID:19969063 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:2475 6480464 [Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in decreased expression of CYP2E1 mRNA CTD PMID:21602191 2,3,7,8-Tetrachlorodibenzofuran increases expression ISO RGD:10451 6480464 2 more ... CTD PMID:25768209 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:2475 6480464 Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2E1 protein CTD PMID:18079364 2,6-dimethylaniline multiple interactions EXP 6480464 fomepizole inhibits the reaction [CYP2E1 protein affects the metabolism of 2, 6-xylidine metabolite] CTD PMID:11409937 2,6-dimethylaniline affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of 2, 6-xylidine metabolite CTD PMID:11409937 2,6-dimethylnaphthalene increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of 2, 6-dimethylnaphthalene CTD PMID:17156750 2-acetamidofluorene multiple interactions ISO RGD:2475 6480464 [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of CYP2E1 mRNA more ... CTD PMID:14656948 more ... 2-acetamidofluorene increases expression ISO RGD:2475 6480464 2-Acetylaminofluorene analog results in increased expression of CYP2E1 protein, 2-Acetylaminofluorene results in increased expression of CYP2E1 protein CTD PMID:15916741 , PMID:23665045 2-amino-2-deoxy-D-galactopyranose decreases expression ISO RGD:2475 6480464 Galactosamine results in decreased expression of CYP2E1 protein CTD PMID:16208626 2-chloroethanol increases expression ISO RGD:2475 6480464 Ethylene Chlorohydrin results in increased expression of CYP2E1 mRNA, Ethylene Chlorohydrin results in increased expression of CYP2E1 protein CTD PMID:31585129 2-chloroethanol multiple interactions ISO RGD:2475 6480464 allyl sulfide inhibits the reaction [Ethylene Chlorohydrin results in increased expression of CYP2E1 mRNA] more ... CTD PMID:31585129 2-naphthol increases abundance EXP 6480464 CYP2E1 protein results in increased abundance of 2-naphthol CTD PMID:16243959 2-nitroanisole increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of 2-nitroanisole CTD PMID:15144223 2-nitroanisole increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of 2-nitroanisole CTD PMID:17159769 , PMID:21218109 2-nitroanisole increases oxidation ISO RGD:2475 6480464 CYP2E1 protein results in increased oxidation of 2-nitroanisole CTD PMID:21218109 2-nitrophenol affects chemical synthesis ISO RGD:2475 6480464 CYP2E1 protein affects the chemical synthesis of 2-nitrophenol CTD PMID:11409192 2-nitrophenol affects chemical synthesis EXP 6480464 CYP2E1 protein affects the chemical synthesis of 2-nitrophenol CTD PMID:11409192 2-nitrophenol increases oxidation ISO RGD:2475 6480464 CYP2E1 protein results in increased oxidation of 2-nitrophenol CTD PMID:20027144 2-nitrophenol increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of 2-nitrophenol CTD PMID:17159769 3,3',4,4',5-pentachlorobiphenyl decreases expression ISO RGD:2475 6480464 3 more ... CTD PMID:19692669 , PMID:23196670 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:28673560 3,3',5-triiodo-L-thyronine increases activity ISO RGD:2475 6480464 Triiodothyronine results in increased activity of CYP2E1 protein CTD PMID:14631868 3,3',5-triiodo-L-thyronine increases expression ISO RGD:2475 6480464 Triiodothyronine results in increased expression of CYP2E1 protein CTD PMID:14631868 3,4-dihydroxybenzoic acid multiple interactions ISO RGD:2475 6480464 [protocatechuic acid co-treated with Methylcholanthrene] results in decreased activity of CYP2E1 protein CTD PMID:15302093 3,4-dihydroxybenzoic acid decreases activity ISO RGD:2475 6480464 protocatechuic acid results in decreased activity of CYP2E1 protein CTD PMID:15302093 3,4-methylenedioxymethamphetamine increases expression ISO RGD:10451 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of CYP2E1 mRNA CTD PMID:26251327 3-(Methylthio)-1-propene decreases expression ISO RGD:2475 6480464 allyl methyl sulfide results in decreased expression of CYP2E1 protein CTD PMID:16000231 , PMID:8117321 3-methylcholanthrene multiple interactions ISO RGD:2475 6480464 [Acetone co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 mRNA more ... CTD PMID:15302093 more ... 3-methylcholanthrene decreases expression ISO RGD:10451 6480464 Methylcholanthrene results in decreased expression of CYP2E1 mRNA CTD PMID:30503582 3-methylcholanthrene decreases expression EXP 6480464 Methylcholanthrene results in decreased expression of CYP2E1 mRNA CTD PMID:28673560 3-methylcholanthrene increases expression ISO RGD:2475 6480464 Methylcholanthrene results in increased expression of CYP2E1 mRNA, Methylcholanthrene results in increased expression of CYP2E1 protein CTD PMID:10476907 more ... 3-methylcholanthrene decreases expression ISO RGD:2475 6480464 Methylcholanthrene results in decreased expression of CYP2E1 mRNA, Methylcholanthrene results in decreased expression of CYP2E1 protein CTD PMID:3113478 more ... 3-methylcholanthrene decreases activity ISO RGD:2475 6480464 Methylcholanthrene results in decreased activity of CYP2E1 protein CTD PMID:8734847 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:12920169 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:12115524 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases activity ISO RGD:2475 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of CYP2E1 protein CTD PMID:9774145 4-methylumbelliferone multiple interactions ISO RGD:10451 6480464 Hymecromone inhibits the reaction [Dietary Fats results in increased activity of CYP2E1 protein] CTD PMID:24661945 4-nitrophenol multiple interactions EXP 6480464 4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased metabolism of Theobromine] more ... CTD PMID:10215755 more ... 4-nitrophenol increases metabolic processing ISO RGD:2475 6480464 CYP2E1 protein results in increased metabolism of 4-nitrophenol CTD PMID:15763544 more ... 4-nitrophenol increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of 4-nitrophenol CTD PMID:10207612 more ... 4-nitrophenol increases hydroxylation ISO RGD:2475 6480464 CYP2E1 protein results in increased hydroxylation of 4-nitrophenol CTD PMID:11408273 more ... 4-nitrophenol multiple interactions ISO RGD:2475 6480464 2-(allylthio)pyrazine inhibits the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol] more ... CTD PMID:1538706 more ... 4-nitrophenol increases hydroxylation ISO RGD:10451 6480464 CYP2E1 protein results in increased hydroxylation of 4-nitrophenol CTD PMID:10094576 , PMID:15742976 4-nitrophenol increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of 4-nitrophenol CTD PMID:12464242 more ... 4-nitrophenol increases hydroxylation EXP 6480464 CYP2E1 protein results in increased hydroxylation of 4-nitrophenol CTD PMID:14669323 more ... 4-nitrophenol affects binding EXP 6480464 4-nitrophenol binds to CYP2E1 protein CTD PMID:24924949 4-Vinylcyclohexene increases metabolic processing ISO RGD:2475 6480464 CYP2E1 protein results in increased metabolism of 4-vinylcyclohexene CTD PMID:11368546 4-Vinylcyclohexene increases expression ISO RGD:10451 6480464 4-vinylcyclohexene results in increased expression of CYP2E1 protein CTD PMID:9929517 4-Vinylcyclohexene multiple interactions ISO RGD:2475 6480464 [CYP2E1 protein results in increased metabolism of 4-vinylcyclohexene] which results in increased abundance of 1, 2-epoxy-4-vinylcyclohexane CTD PMID:11368546 4-vinylcyclohexene dioxide affects response to substance ISO RGD:10451 6480464 CYP2E1 protein affects the susceptibility to 4-vinyl-1-cyclohexene dioxide CTD PMID:18622027 5-(2-chloroethyl)-4-methylthiazole multiple interactions ISO RGD:10451 6480464 Chlormethiazole inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA] more ... CTD PMID:21684301 more ... 5-(2-chloroethyl)-4-methylthiazole multiple interactions EXP 6480464 [Chlormethiazole results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone, Chlormethiazole inhibits the reaction [Docosahexaenoic Acids results in increased expression of CYP2E1 protein] CTD PMID:16963249 , PMID:26599973 5-(2-chloroethyl)-4-methylthiazole decreases expression EXP 6480464 Chlormethiazole results in decreased expression of CYP2E1 protein CTD PMID:16963249 5-(2-chloroethyl)-4-methylthiazole decreases activity EXP 6480464 Chlormethiazole results in decreased activity of CYP2E1 protein CTD PMID:26599973 5-(2-chloroethyl)-4-methylthiazole decreases activity ISO RGD:2475 6480464 Chlormethiazole results in decreased activity of CYP2E1 protein CTD PMID:16330492 5-(2-chloroethyl)-4-methylthiazole decreases expression ISO RGD:2475 6480464 Chlormethiazole results in decreased expression of CYP2E1 mRNA, Chlormethiazole results in decreased expression of CYP2E1 protein CTD PMID:10751552 , PMID:7601153 5-(2-chloroethyl)-4-methylthiazole multiple interactions ISO RGD:2475 6480464 Chlormethiazole inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol], Chlormethiazole inhibits the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride] CTD PMID:7601153 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole multiple interactions EXP 6480464 Omeprazole results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:15802389 5-methoxy-N,N-diisopropyltryptamine decreases activity EXP 6480464 5-methoxy-N, N-diisopropyltryptamine analog results in decreased activity of CYP2E1 protein CTD PMID:26599973 5-methoxy-N,N-diisopropyltryptamine multiple interactions EXP 6480464 [5-methoxy-N, N-diisopropyltryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone CTD PMID:26599973 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime multiple interactions EXP 6480464 [6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:30611723 7,12-dimethyltetraphene affects response to substance ISO RGD:10451 6480464 CYP2E1 protein affects the susceptibility to 9 more ... CTD PMID:18622027 7,12-dimethyltetraphene increases expression ISO RGD:2475 6480464 9 more ... CTD PMID:24576726 7-ethoxycoumarin increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of 7-ethoxycoumarin CTD PMID:18385292 8-Br-cAMP increases expression EXP 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP2E1 mRNA CTD PMID:22079614 acarbose decreases expression ISO RGD:2475 6480464 Acarbose results in decreased expression of CYP2E1 mRNA CTD PMID:14975757 acephate multiple interactions ISO RGD:10451 6480464 [acephate co-treated with vinclozolin] affects the expression of CYP2E1 protein more ... CTD PMID:17686559 acetaldehyde increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Acetaldehyde CTD PMID:10826103 acetaldehyde multiple interactions EXP 6480464 [CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Acetaldehyde CTD PMID:18845238 acetaldehyde multiple interactions ISO RGD:2475 6480464 [CYP2E1 protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde, phenethyl isothiocyanate inhibits the reaction [[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde] CTD PMID:7562599 acetic acid increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Acetic Acid analog CTD PMID:21933969 acetone multiple interactions ISO RGD:10451 6480464 [Acetone results in increased activity of CYP2E1 protein] which results in increased oxidation of Benzene more ... CTD PMID:18990727 more ... acetone increases expression ISO RGD:2475 6480464 Acetone results in increased expression of CYP2E1 mRNA, Acetone results in increased expression of CYP2E1 protein CTD PMID:11939710 more ... acetone increases activity ISO RGD:2475 6480464 Acetone results in increased activity of CYP2E1 protein CTD PMID:12919724 more ... acetone increases expression ISO RGD:10451 6480464 Acetone results in increased expression of CYP2E1 mRNA, Acetone results in increased expression of CYP2E1 protein CTD PMID:18990727 , PMID:22499231 acetone multiple interactions ISO RGD:2475 6480464 1 more ... CTD PMID:7587954 more ... acetone increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Acetone CTD PMID:15576447 acetonitrile multiple interactions ISO RGD:2475 6480464 acetonitrile inhibits the reaction [CYP2E1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 acetonitrile multiple interactions EXP 6480464 acetonitrile inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] CTD PMID:9143349 acetylsalicylic acid increases expression ISO RGD:2475 6480464 Aspirin results in increased expression of CYP2E1 mRNA CTD PMID:11752103 acrylamide affects expression ISO RGD:2475 6480464 Acrylamide affects the expression of CYP2E1 mRNA CTD PMID:28959563 acrylamide affects metabolic processing EXP 6480464 CYP2E1 intron polymorphism affects the metabolism of Acrylamide CTD PMID:29748789 acrylamide increases expression ISO RGD:2475 6480464 Acrylamide results in increased expression of CYP2E1 mRNA CTD PMID:28606764 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of CYP2E1 protein CTD PMID:24508477 acrylamide affects response to substance EXP 6480464 CYP2E1 protein affects the susceptibility to Acrylamide CTD PMID:24508477 acrylamide multiple interactions ISO RGD:10451 6480464 [CYP2E1 protein results in increased oxidation of Acrylamide] which results in increased abundance of glycidamide CTD PMID:27174446 acrylamide multiple interactions EXP 6480464 [CYP2E1 gene polymorphism co-treated with GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] affects the metabolism of Acrylamide more ... CTD PMID:19131562 , PMID:24508477 acrylamide increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to Acrylamide CTD PMID:15355880 , PMID:17267090 acrylamide increases oxidation ISO RGD:10451 6480464 CYP2E1 protein results in increased oxidation of Acrylamide CTD PMID:15355880 acrylamide affects metabolic processing ISO RGD:10451 6480464 CYP2E1 protein affects the metabolism of Acrylamide CTD PMID:17979661 acrylamide affects expression EXP 6480464 Acrylamide affects the expression of CYP2E1 mRNA CTD PMID:17267090 acrylonitrile affects response to substance ISO RGD:2475 6480464 CYP2E1 protein affects the susceptibility to Acrylonitrile CTD PMID:20127315 acrylonitrile increases expression ISO RGD:2475 6480464 Acrylonitrile results in increased expression of CYP2E1 mRNA CTD PMID:26332274 acrylonitrile increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of Acrylonitrile CTD PMID:1664256 acrylonitrile multiple interactions ISO RGD:2475 6480464 Acetylcysteine promotes the reaction [Acrylonitrile results in increased expression of CYP2E1 mRNA] more ... CTD PMID:26332274 , PMID:9010585 acteoside multiple interactions ISO RGD:2475 6480464 acteoside inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein] CTD PMID:14672760 aflatoxin B1 affects expression EXP 6480464 Aflatoxin B1 affects the expression of CYP2E1 protein CTD PMID:20106945 aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of CYP2E1 mRNA CTD PMID:22100608 , PMID:27153756 aflatoxin B1 increases expression ISO RGD:2475 6480464 Aflatoxin B1 results in increased expression of CYP2E1 mRNA CTD PMID:23630614 aflatoxin B1 decreases expression ISO RGD:10451 6480464 Aflatoxin B1 results in decreased expression of CYP2E1 mRNA CTD PMID:19770486 alcohol increases activity EXP 6480464 Alcohols results in increased activity of CYP2E1 protein CTD PMID:24025710 alcohol multiple interactions ISO RGD:10451 6480464 Apigenin inhibits the reaction [Alcohols results in increased expression of CYP2E1 protein], Glutathione inhibits the reaction [Alcohols results in increased expression of CYP2E1 protein] CTD PMID:28803762 alcohol increases expression ISO RGD:10451 6480464 Alcohols results in increased expression of CYP2E1 protein CTD PMID:28803762 alcohol increases expression EXP 6480464 Alcohols results in increased expression of CYP2E1 mRNA CTD PMID:24025710 alcohol multiple interactions EXP 6480464 Alcohols inhibits the reaction [ferric citrate results in increased expression of CYP2E1 mRNA], ferric citrate inhibits the reaction [Alcohols results in increased expression of CYP2E1 mRNA] CTD PMID:24025710 alizarin decreases activity EXP 6480464 alizarin results in decreased activity of CYP2E1 protein CTD PMID:12379470 alkaloid multiple interactions ISO RGD:2475 6480464 Alkaloids inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA], Alkaloids inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 protein] CTD PMID:21224420 all-trans-retinoic acid multiple interactions EXP 6480464 Tretinoin promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] CTD PMID:8531136 all-trans-retinoic acid increases expression ISO RGD:2475 6480464 Tretinoin results in increased expression of CYP2E1 mRNA CTD PMID:24977338 allethrin multiple interactions ISO RGD:2475 6480464 Allethrins results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:22080754 allyl alcohol increases expression ISO RGD:10451 6480464 allyl alcohol results in increased expression of CYP2E1 protein CTD PMID:11515535 alpha-hexachlorocyclohexane multiple interactions ISO RGD:2475 6480464 [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2E1 protein CTD PMID:16246485 alpha-linolenic acid decreases activity EXP 6480464 alpha-Linolenic Acid results in decreased activity of CYP2E1 protein CTD PMID:16978661 alpha-methyltryptamine decreases activity EXP 6480464 indopan analog results in decreased activity of CYP2E1 protein, indopan results in decreased activity of CYP2E1 protein CTD PMID:26599973 alpha-methyltryptamine multiple interactions EXP 6480464 [indopan analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone, [indopan results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone CTD PMID:26599973 amiodarone decreases response to substance EXP 6480464 CYP2E1 protein results in decreased susceptibility to Amiodarone CTD PMID:26477383 amitraz increases expression ISO RGD:2475 6480464 amitraz results in increased expression of CYP2E1 protein CTD PMID:31029719 amitrole decreases activity EXP 6480464 Amitrole results in decreased activity of CYP2E1 protein CTD PMID:12464242 ammonium chloride affects expression ISO RGD:2475 6480464 Ammonium Chloride affects the expression of CYP2E1 mRNA CTD PMID:16483693 amphibole asbestos affects expression EXP 6480464 Asbestos, Amphibole affects the expression of CYP2E1 protein CTD PMID:20855422 ampicillin multiple interactions ISO RGD:2475 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2E1 mRNA CTD PMID:30545405 angelicin decreases expression ISO RGD:10451 6480464 angelicin results in decreased expression of CYP2E1 protein CTD PMID:22173200 aniline multiple interactions ISO RGD:2475 6480464 [Benzene results in increased expression of CYP2E1 protein] which results in increased metabolism of aniline more ... CTD PMID:11330834 more ... aniline increases metabolic processing ISO RGD:2475 6480464 CYP2E1 protein results in increased metabolism of aniline CTD PMID:26463279 aniline increases hydroxylation ISO RGD:2475 6480464 CYP2E1 protein results in increased hydroxylation of aniline CTD PMID:23274713 aniline increases hydroxylation ISO RGD:10451 6480464 CYP2E1 protein results in increased hydroxylation of aniline CTD PMID:18038910 more ... aniline multiple interactions ISO RGD:10451 6480464 caffeic acid phenethyl ester inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline] more ... CTD PMID:18038910 more ... aniline increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of aniline CTD PMID:12464242 , PMID:8819299 aniline multiple interactions EXP 6480464 CYP2E1 protein affects the metabolism of [norharman co-treated with aniline] more ... CTD PMID:15279827 more ... aniline increases hydroxylation EXP 6480464 CYP2E1 protein results in increased hydroxylation of aniline CTD PMID:8858968 , PMID:9195021 aniline decreases activity EXP 6480464 aniline results in decreased activity of CYP2E1 protein CTD PMID:12814958 , PMID:15306208 anthocyanin increases expression ISO RGD:2475 6480464 Anthocyanins results in increased expression of CYP2E1 mRNA CTD PMID:18803703 apigenin multiple interactions ISO RGD:10451 6480464 Apigenin inhibits the reaction [Alcohols results in increased expression of CYP2E1 protein] CTD PMID:28803762 apigenin decreases activity EXP 6480464 Apigenin results in decreased activity of CYP2E1 protein CTD PMID:29753067 arachidonic acid affects hydroxylation ISO RGD:2475 6480464 CYP2E1 protein affects the hydroxylation of Arachidonic Acid CTD PMID:15205388 arachidonic acid decreases activity EXP 6480464 Arachidonic Acid results in decreased activity of CYP2E1 protein CTD PMID:16978661 arachidonic acid increases response to substance EXP 6480464 CYP2E1 results in increased susceptibility to Arachidonic Acid CTD PMID:12566070 arachidonic acid multiple interactions EXP 6480464 [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT18 protein more ... CTD PMID:12086689 more ... arecoline increases activity ISO RGD:2475 6480464 Arecoline analog results in increased activity of CYP2E1 protein CTD PMID:25056785 Aroclor 1254 decreases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP2E1 mRNA CTD PMID:17851650 Aroclor 1254 decreases expression ISO RGD:2475 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP2E1 mRNA, Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP2E1 protein CTD PMID:3113478 , PMID:8471063 arsane affects expression EXP 6480464 Arsenic affects the expression of CYP2E1 mRNA CTD PMID:18414638 arsane multiple interactions ISO RGD:2475 6480464 Arsenic inhibits the reaction [Acetaminophen results in increased activity of CYP2E1 protein] CTD PMID:19932728 arsane decreases activity ISO RGD:2475 6480464 Arsenic results in decreased activity of CYP2E1 protein CTD PMID:19932728 arsenic atom affects expression EXP 6480464 Arsenic affects the expression of CYP2E1 mRNA CTD PMID:18414638 arsenic atom decreases activity ISO RGD:2475 6480464 Arsenic results in decreased activity of CYP2E1 protein CTD PMID:19932728 arsenic atom multiple interactions ISO RGD:2475 6480464 Arsenic inhibits the reaction [Acetaminophen results in increased activity of CYP2E1 protein] CTD PMID:19932728 arsenous acid affects expression EXP 6480464 Arsenic Trioxide affects the expression of CYP2E1 mRNA CTD PMID:17530438 asiatic acid multiple interactions ISO RGD:2475 6480464 asiatic acid inhibits the reaction [1, 2-Dimethylhydrazine results in increased activity of CYP2E1 protein] CTD PMID:29108773 aspartame multiple interactions ISO RGD:2475 6480464 Aspartame results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:16937917 atrazine increases expression ISO RGD:10451 6480464 Atrazine results in increased expression of CYP2E1 mRNA CTD PMID:26775023 atrazine multiple interactions ISO RGD:10451 6480464 lycopene inhibits the reaction [Atrazine results in increased expression of CYP2E1 mRNA] CTD PMID:26775023 baicalein decreases activity EXP 6480464 baicalein results in decreased activity of CYP2E1 protein CTD PMID:29753067 benzene increases oxidation ISO RGD:10451 6480464 CYP2E1 protein results in increased oxidation of Benzene CTD PMID:8560479 benzene decreases methylation EXP 6480464 Benzene results in decreased methylation of CYP2E1 promoter CTD PMID:28823944 benzene multiple interactions EXP 6480464 [CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of catechol more ... CTD PMID:15051535 benzene affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of Benzene CTD PMID:15051535 , PMID:15226677 benzene increases oxidation ISO RGD:2475 6480464 CYP2E1 protein results in increased oxidation of Benzene CTD PMID:9118895 benzene increases metabolic processing ISO RGD:2475 6480464 CYP2E1 protein results in increased metabolism of Benzene CTD PMID:1739413 more ... benzene affects response to substance ISO RGD:2475 6480464 CYP2E1 protein affects the susceptibility to Benzene CTD PMID:9118891 benzene increases expression ISO RGD:2475 6480464 Benzene results in increased expression of CYP2E1 mRNA, Benzene results in increased expression of CYP2E1 protein CTD PMID:12919724 more ... benzene increases activity ISO RGD:2475 6480464 Benzene results in increased activity of CYP2E1 protein CTD PMID:12919724 more ... benzene affects response to substance ISO RGD:10451 6480464 CYP2E1 protein affects the susceptibility to Benzene CTD PMID:8560479 benzene increases hydroxylation EXP 6480464 CYP2E1 protein alternative form results in increased hydroxylation of Benzene, CYP2E1 protein results in increased hydroxylation of Benzene CTD PMID:15122651 , PMID:20033806 benzene increases expression EXP 6480464 Benzene results in increased expression of CYP2E1 mRNA CTD PMID:18952161 benzene affects response to substance EXP 6480464 CYP2E1 gene polymorphism affects the susceptibility to Benzene more ... CTD PMID:12460800 more ... benzene decreases expression ISO RGD:2475 6480464 Benzene results in decreased expression of CYP2E1 protein CTD PMID:15274493 benzene affects expression ISO RGD:2475 6480464 Benzene affects the expression of CYP2E1 mRNA CTD PMID:15878777 benzene decreases activity ISO RGD:2475 6480464 Benzene results in decreased activity of CYP2E1 protein CTD PMID:18407866 benzene increases hydroxylation ISO RGD:10451 6480464 CYP2E1 protein results in increased hydroxylation of Benzene CTD PMID:11718959 , PMID:14718178 benzene increases expression ISO RGD:10451 6480464 Benzene results in increased expression of CYP2E1 mRNA, Benzene results in increased expression of CYP2E1 protein CTD PMID:12388843 more ... benzene increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Benzene CTD PMID:17885617 more ... benzene increases response to substance EXP 6480464 CYP2E1 gene polymorphism results in increased susceptibility to Benzene CTD PMID:15226677 benzene decreases activity ISO RGD:10451 6480464 Benzene results in decreased activity of CYP2E1 protein CTD PMID:8751834 benzene multiple interactions ISO RGD:10451 6480464 [Acetone results in increased activity of CYP2E1 protein] which results in increased oxidation of Benzene more ... CTD PMID:12388843 more ... benzene increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of Benzene CTD PMID:10207612 more ... benzene multiple interactions ISO RGD:2475 6480464 [Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene more ... CTD PMID:18407866 more ... benzene increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to Benzene CTD PMID:8917693 benzene increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of Benzene CTD PMID:11376689 , PMID:8461037 benzene-1,2,4-triol multiple interactions EXP 6480464 [CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of hydroxyhydroquinone CTD PMID:15051535 benzo[a]pyrene increases mutagenesis EXP 6480464 Benzo(a)pyrene results in increased mutagenesis of CYP2E1 gene CTD PMID:25435355 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of CYP2E1 mRNA CTD PMID:16269432 benzo[a]pyrene increases expression ISO RGD:2475 6480464 Benzo(a)pyrene results in increased expression of CYP2E1 mRNA, Benzo(a)pyrene results in increased expression of CYP2E1 protein CTD PMID:19889059 , PMID:21383588 benzo[a]pyrene decreases expression ISO RGD:10451 6480464 Benzo(a)pyrene results in decreased expression of CYP2E1 mRNA CTD PMID:19770486 , PMID:20127859 benzo[b]fluoranthene increases expression EXP 6480464 benzo(b)fluoranthene results in increased expression of CYP2E1 mRNA CTD PMID:16269432 benzylideneacetone increases oxidation ISO RGD:2475 6480464 CYP2E1 protein results in increased oxidation of benzylideneacetone CTD PMID:15863696 berberine decreases expression ISO RGD:10451 6480464 Berberine results in decreased expression of CYP2E1 mRNA CTD PMID:22342832 berberine multiple interactions ISO RGD:10451 6480464 Berberine inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein], Berberine inhibits the reaction [Isoniazid results in increased expression of CYP2E1 mRNA] CTD PMID:22342832 , PMID:25455889 Besigomsin affects binding ISO RGD:10451 6480464 schizandrol B binds to CYP2E1 protein CTD PMID:25319358 Besigomsin multiple interactions ISO RGD:10451 6480464 schizandrol B inhibits the reaction [CYP2E1 protein results in increased metabolism of and results in increased activity of Acetaminophen] CTD PMID:25319358 Besigomsin decreases activity ISO RGD:10451 6480464 schizandrol B results in decreased activity of CYP2E1 protein CTD PMID:25319358 beta-carboline multiple interactions EXP 6480464 CYP2E1 protein affects the metabolism of [norharman co-treated with aniline] CTD PMID:15279827 beta-naphthoflavone decreases expression EXP 6480464 beta-Naphthoflavone results in decreased expression of CYP2E1 mRNA CTD PMID:22258563 beta-naphthoflavone increases expression EXP 6480464 beta-Naphthoflavone results in increased expression of CYP2E1 mRNA, beta-Naphthoflavone results in increased expression of CYP2E1 protein CTD PMID:30373287 beta-naphthoflavone multiple interactions ISO RGD:2475 6480464 [Phenobarbital co-treated with beta-Naphthoflavone] results in decreased expression of CYP2E1 protein CTD PMID:30842367 beta-naphthoflavone increases expression ISO RGD:2475 6480464 beta-Naphthoflavone results in increased expression of CYP2E1 mRNA CTD PMID:19969063 bifenthrin increases expression ISO RGD:10451 6480464 bifenthrin results in increased expression of CYP2E1 mRNA CTD PMID:26071804 bilobalide increases activity ISO RGD:2475 6480464 bilobalide results in increased activity of CYP2E1 protein CTD PMID:18421621 biotin multiple interactions EXP 6480464 Biotin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] CTD PMID:9143349 biphenyl-4-amine increases hydroxylation ISO RGD:10451 6480464 CYP2E1 protein results in increased hydroxylation of 4-biphenylamine CTD PMID:25601990 biphenyl-4-amine multiple interactions ISO RGD:10451 6480464 [CYP2E1 protein results in increased hydroxylation of 4-biphenylamine] which results in increased abundance of Reactive Oxygen Species CTD PMID:25601990 biphenyl-4-amine decreases response to substance ISO RGD:10451 6480464 CYP2E1 gene mutant form results in decreased susceptibility to 4-biphenylamine CTD PMID:25601990 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of CYP2E1 mRNA CTD PMID:31163220 bisphenol A increases glutathionylation EXP 6480464 CYP2E1 protein results in increased glutathionylation of bisphenol A metabolite CTD PMID:23470418 bisphenol A increases expression ISO RGD:10451 6480464 bisphenol A results in increased expression of CYP2E1 mRNA CTD PMID:30245210 bisphenol A multiple interactions ISO RGD:10451 6480464 [LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of CYP2E1 mRNA CTD PMID:28123100 bisphenol A increases response to substance EXP 6480464 CYP2E1 protein results in increased susceptibility to bisphenol A CTD PMID:27491884 bisphenol A increases methylation ISO RGD:10451 6480464 bisphenol A results in increased methylation of CYP2E1 promoter CTD PMID:27312807 bisphenol A affects expression ISO RGD:2475 6480464 bisphenol A affects the expression of CYP2E1 mRNA CTD PMID:25181051 , PMID:30903817 bisphenol A increases hydroxylation EXP 6480464 CYP2E1 protein results in increased hydroxylation of bisphenol A, CYP2E1 protein results in increased hydroxylation of bisphenol A metabolite CTD PMID:23470418 bisphenol F increases glutathionylation EXP 6480464 CYP2E1 protein results in increased glutathionylation of 4, 4'-bisphenol F metabolite CTD PMID:23470418 bisphenol F increases hydroxylation EXP 6480464 CYP2E1 protein results in increased hydroxylation of 4, 4'-bisphenol F CTD PMID:23470418 Bromadiolone increases expression ISO RGD:2475 6480464 bromadiolone results in increased expression of CYP2E1 mRNA CTD PMID:18080289 Bromadiolone decreases response to substance ISO RGD:2475 6480464 CYP2E1 protein results in decreased susceptibility to bromadiolone CTD PMID:18080289 bromobenzene increases expression ISO RGD:2475 6480464 bromobenzene results in increased expression of CYP2E1 mRNA CTD PMID:12628495 bromodichloromethane increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of bromodichloromethane CTD PMID:12076521 more ... bromodichloromethane multiple interactions ISO RGD:10451 6480464 [Dietary Fats co-treated with bromodichloromethane] results in increased expression of CYP2E1 protein more ... CTD PMID:23438451 , PMID:24211274 bromodichloromethane increases metabolic processing ISO RGD:2475 6480464 CYP2E1 protein results in increased metabolism of bromodichloromethane CTD PMID:11295256 , PMID:12076521 bromodichloromethane increases expression ISO RGD:2475 6480464 bromodichloromethane results in increased expression of CYP2E1 protein CTD PMID:11295256 bromodichloromethane multiple interactions ISO RGD:2475 6480464 CYP2E1 protein results in increased metabolism of and results in increased activity of bromodichloromethane CTD PMID:9458004 bromodichloromethane decreases response to substance ISO RGD:10451 6480464 CYP2E1 gene mutant form results in decreased susceptibility to bromodichloromethane CTD PMID:23640861 bromoethene increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of vinyl bromide CTD PMID:1664256 brucine multiple interactions ISO RGD:2475 6480464 [brucine co-treated with Glycyrrhetinic Acid] results in decreased activity of CYP2E1 protein, [brucine co-treated with liquiritin] results in decreased activity of CYP2E1 protein CTD PMID:21800547 brucine increases activity ISO RGD:2475 6480464 brucine results in increased activity of CYP2E1 protein CTD PMID:21800547 bucladesine multiple interactions EXP 6480464 Bucladesine promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] CTD PMID:8531136 buta-1,3-diene multiple interactions ISO RGD:10451 6480464 1 more ... CTD PMID:10828257 buta-1,3-diene increases oxidation ISO RGD:10451 6480464 CYP2E1 protein results in increased oxidation of 1, 3-butadiene CTD PMID:10828257 buta-1,3-diene affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of 1, 3-butadiene CTD PMID:15470755 butan-2-one affects response to substance EXP 6480464 CYP2E1 gene mutant form affects the susceptibility to methylethyl ketone CTD PMID:21352904 butane-1,3-diol increases expression ISO RGD:2475 6480464 1, 3-butylene glycol results in increased expression of CYP2E1 protein CTD PMID:2919394 butane-1,3-diol increases activity ISO RGD:2475 6480464 1, 3-butylene glycol results in increased activity of CYP2E1 protein CTD PMID:2919394 Butylbenzyl phthalate decreases activity ISO RGD:2475 6480464 butylbenzyl phthalate results in decreased activity of CYP2E1 protein CTD PMID:27432241 C60 fullerene increases expression ISO RGD:2475 6480464 fullerene C60 results in increased expression of CYP2E1 mRNA CTD PMID:19167457 cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of CYP2E1 mRNA CTD PMID:21120746 cadmium dichloride decreases expression ISO RGD:10451 6480464 Cadmium Chloride results in decreased expression of CYP2E1 mRNA CTD PMID:11958953 cadmium dichloride multiple interactions EXP 6480464 Cadmium Chloride affects the reaction [CYP2E1 protein results in increased susceptibility to Arachidonic Acid] CTD PMID:12566070 cafestol decreases activity ISO RGD:10451 6480464 cafestol results in decreased activity of CYP2E1 protein CTD PMID:17590492 caffeine affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of Caffeine CTD PMID:1302044 , PMID:14586387 calcium atom affects expression ISO RGD:2475 6480464 Calcium affects the expression of CYP2E1 mRNA CTD PMID:15913539 calcium atom decreases uptake EXP 6480464 CYP2E1 protein results in decreased uptake of Calcium CTD PMID:19028543 calcium(0) affects expression ISO RGD:2475 6480464 Calcium affects the expression of CYP2E1 mRNA CTD PMID:15913539 calcium(0) decreases uptake EXP 6480464 CYP2E1 protein results in decreased uptake of Calcium CTD PMID:19028543 canadine increases expression ISO RGD:10451 6480464 canadine results in increased expression of CYP2E1 mRNA, canadine results in increased expression of CYP2E1 protein CTD PMID:28257954 capsaicin increases expression ISO RGD:2475 6480464 Capsaicin results in increased expression of CYP2E1 CTD PMID:22375877 carbamazepine decreases expression ISO RGD:2475 6480464 Carbamazepine results in decreased expression of CYP2E1 mRNA CTD PMID:17381134 carbaryl decreases activity EXP 6480464 Carbaryl results in decreased activity of CYP2E1 protein CTD PMID:22634058 carbaryl multiple interactions EXP 6480464 Carbaryl inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:22634058 carbon monoxide decreases activity EXP 6480464 Carbon Monoxide results in decreased activity of CYP2E1 protein CTD PMID:15036350 carbon monoxide multiple interactions ISO RGD:2475 6480464 Carbon Monoxide inhibits the reaction [CYP2E1 protein results in increased reduction of sodium chromate(VI)] CTD PMID:1903091 carbon nanotube decreases expression ISO RGD:10451 6480464 Nanotubes, Carbon analog results in decreased expression of CYP2E1 mRNA, Nanotubes, Carbon results in decreased expression of CYP2E1 mRNA CTD PMID:25554681 carnosine multiple interactions ISO RGD:10451 6480464 Carnosine inhibits the reaction [Acetaminophen results in increased activity of CYP2E1 protein] CTD PMID:19799668 catechol multiple interactions ISO RGD:2475 6480464 [CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of catechol, EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of catechol] CTD PMID:8211999 catechol multiple interactions EXP 6480464 [CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of catechol CTD PMID:15051535 chenodeoxycholic acid decreases expression EXP 6480464 Chenodeoxycholic Acid results in decreased expression of CYP2E1 mRNA CTD PMID:27174168 CHIR 99021 increases expression EXP 6480464 Chir 99021 results in increased expression of CYP2E1 mRNA CTD PMID:26259606 CHIR 99021 multiple interactions EXP 6480464 Chir 99021 results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:26259606 chloral hydrate multiple interactions ISO RGD:2475 6480464 [CYP2E1 protein results in increased metabolism of Trichloroethylene] which results in increased chemical synthesis of Chloral Hydrate CTD PMID:1739413 chloral hydrate increases chemical synthesis ISO RGD:2475 6480464 CYP2E1 protein results in increased chemical synthesis of Chloral Hydrate CTD PMID:1739413 chlorfluazuron multiple interactions EXP 6480464 chlorfluazuron inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:22634058 chlorfluazuron decreases activity EXP 6480464 chlorfluazuron results in decreased activity of CYP2E1 protein CTD PMID:22634058 chlorobenzene multiple interactions EXP 6480464 dihydroxyethyldithiocarbamate inhibits the reaction [CYP2E1 protein results in increased metabolism of chlorobenzene] CTD PMID:9817075 chlorobenzene increases oxidation ISO RGD:2475 6480464 CYP2E1 protein results in increased oxidation of chlorobenzene CTD PMID:9817075 chlorobenzene multiple interactions ISO RGD:2475 6480464 [Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of chlorobenzene more ... CTD PMID:9010585 , PMID:9817075 chlorobenzene increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of chlorobenzene CTD PMID:9817075 chloroethene multiple interactions EXP 6480464 CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of KRAS gene] more ... CTD PMID:12010862 more ... chloroethene increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of Vinyl Chloride CTD PMID:1664256 chloroethene affects response to substance EXP 6480464 CYP2E1 gene polymorphism affects the susceptibility to Vinyl Chloride CTD PMID:20134343 chloroethene increases activity ISO RGD:2475 6480464 Vinyl Chloride results in increased activity of CYP2E1 protein CTD PMID:15211785 , PMID:17710613 chloroethene multiple interactions ISO RGD:2475 6480464 1, 2-dichloroethylene inhibits the reaction [CYP2E1 protein affects the metabolism of Vinyl Chloride] CTD PMID:7871537 chloroethene affects metabolic processing ISO RGD:2475 6480464 CYP2E1 protein affects the metabolism of Vinyl Chloride CTD PMID:17710613 , PMID:7871537 chloroethene increases activity EXP 6480464 Vinyl Chloride results in increased activity of CYP2E1 protein CTD PMID:17710613 chloroethene increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Vinyl Chloride CTD PMID:18350910 chloroethene affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of Vinyl Chloride CTD PMID:17710613 chloroethene increases response to substance EXP 6480464 CYP2E1 gene polymorphism results in increased susceptibility to Vinyl Chloride, CYP2E1 gene SNP results in increased susceptibility to Vinyl Chloride CTD PMID:16270392 more ... chloroform increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Chloroform CTD PMID:18350910 chloroform increases response to substance EXP 6480464 CYP2E1 gene SNP results in increased susceptibility to Chloroform CTD PMID:15289170 chloroform increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of Chloroform CTD PMID:1664256 chlorogenic acid multiple interactions ISO RGD:10451 6480464 Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of CYP2E1 protein] CTD PMID:25043994 chloromethane increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of Methyl Chloride CTD PMID:1664256 chloroprene increases expression ISO RGD:2475 6480464 Chloroprene results in increased expression of CYP2E1 mRNA CTD PMID:23125180 chlorpromazine decreases activity EXP 6480464 Chlorpromazine results in decreased activity of CYP2E1 protein CTD PMID:15135088 chlorpromazine decreases response to substance EXP 6480464 CYP2E1 protein results in decreased susceptibility to Chlorpromazine CTD PMID:26477383 chlorpyrifos decreases activity EXP 6480464 Chlorpyrifos results in decreased activity of CYP2E1 protein CTD PMID:22634058 chlorpyrifos multiple interactions EXP 6480464 Chlorpyrifos inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:22634058 chlorzoxazone affects hydroxylation EXP 6480464 CYP2E1 protein affects the hydroxylation of Chlorzoxazone CTD PMID:7747284 chlorzoxazone increases metabolic processing ISO RGD:2475 6480464 CYP2E1 protein results in increased metabolism of Chlorzoxazone CTD PMID:28438436 chlorzoxazone increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of Chlorzoxazone CTD PMID:25956474 more ... chlorzoxazone multiple interactions ISO RGD:10451 6480464 [CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased abundance of 6-hydroxychlorzoxazone more ... CTD PMID:25956474 more ... chlorzoxazone increases hydroxylation EXP 6480464 CYP2E1 protein results in increased hydroxylation of Chlorzoxazone CTD PMID:12433797 more ... chlorzoxazone increases metabolic processing EXP 6480464 CYP2E1 mRNA results in increased metabolism of Chlorzoxazone, CYP2E1 protein results in increased metabolism of Chlorzoxazone CTD PMID:12401345 more ... chlorzoxazone increases hydroxylation ISO RGD:10451 6480464 CYP2E1 protein results in increased hydroxylation of Chlorzoxazone CTD PMID:10463382 chlorzoxazone increases hydroxylation ISO RGD:2475 6480464 CYP2E1 protein results in increased hydroxylation of Chlorzoxazone CTD PMID:11911841 more ... chlorzoxazone affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of Chlorzoxazone CTD PMID:12818727 more ... chlorzoxazone multiple interactions ISO RGD:2475 6480464 [CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone more ... CTD PMID:21600194 , PMID:28438436 chlorzoxazone increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of Chlorzoxazone CTD PMID:10207612 , PMID:21964418 chlorzoxazone affects metabolic processing ISO RGD:2475 6480464 CYP2E1 protein affects the metabolism of Chlorzoxazone CTD PMID:15231049 , PMID:15879494 chlorzoxazone multiple interactions EXP 6480464 [5-bromotryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone more ... CTD PMID:11502731 more ... cholesterol decreases activity ISO RGD:10451 6480464 Cholesterol results in decreased activity of CYP2E1 protein CTD PMID:18420780 choline multiple interactions ISO RGD:2475 6480464 [Methionine deficiency co-treated with Choline deficiency] results in increased expression of CYP2E1 protein more ... CTD PMID:18798224 , PMID:26695085 choline multiple interactions ISO RGD:10451 6480464 [Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein] more ... CTD PMID:18952117 more ... chrysene increases expression ISO RGD:10451 6480464 chrysene results in increased expression of CYP2E1 mRNA CTD PMID:26377693 ciguatoxin CTX1B affects expression ISO RGD:10451 6480464 Ciguatoxins affects the expression of CYP2E1 mRNA CTD PMID:18353800 cimetidine multiple interactions EXP 6480464 [Monocrotophos co-treated with Cimetidine] results in increased expression of CYP2E1 protein CTD PMID:22733800 cimetidine decreases expression EXP 6480464 Cimetidine results in decreased expression of CYP2E1 protein CTD PMID:22733800 cinnamic acid decreases activity EXP 6480464 cinnamic acid analog results in decreased activity of CYP2E1 protein CTD PMID:15072549 ciprofibrate multiple interactions ISO RGD:2475 6480464 [Acetone co-treated with ciprofibrate] results in increased expression of CYP2E1 protein more ... CTD PMID:7587954 ciprofibrate increases expression ISO RGD:2475 6480464 ciprofibrate results in increased expression of CYP2E1 mRNA CTD PMID:7587954 cis-caffeic acid multiple interactions ISO RGD:2475 6480464 caffeic acid inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] CTD PMID:7710944 cisplatin decreases activity ISO RGD:2475 6480464 Cisplatin results in decreased activity of CYP2E1 protein CTD PMID:24882083 cisplatin increases response to substance ISO RGD:2475 6480464 CYP2E1 protein results in increased susceptibility to Cisplatin CTD PMID:20809784 cisplatin increases expression ISO RGD:2475 6480464 Cisplatin results in increased expression of CYP2E1 mRNA CTD PMID:22023808 cisplatin multiple interactions ISO RGD:10451 6480464 Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of CYP2E1 protein] more ... CTD PMID:21616140 more ... cisplatin increases expression ISO RGD:10451 6480464 Cisplatin results in increased expression of CYP2E1 protein CTD PMID:23770416 , PMID:25043994 cisplatin multiple interactions ISO RGD:2475 6480464 turmeric extract affects the reaction [Cisplatin results in decreased activity of CYP2E1 protein] CTD PMID:24882083 citral multiple interactions EXP 6480464 [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral, [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite CTD PMID:18824010 clofibrate multiple interactions ISO RGD:10451 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of CYP2E1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CYP2E1 mRNA] CTD PMID:17585979 clofibrate increases expression ISO RGD:2475 6480464 Clofibrate results in increased expression of CYP2E1 mRNA, Clofibrate results in increased expression of CYP2E1 protein CTD PMID:10476907 copper atom multiple interactions EXP 6480464 [CYP2E1 protein co-treated with Copper] results in increased activity of Eugenol CTD PMID:15576237 copper atom decreases expression ISO RGD:2475 6480464 Copper results in decreased expression of CYP2E1 mRNA CTD PMID:22465980 copper(0) multiple interactions EXP 6480464 [CYP2E1 protein co-treated with Copper] results in increased activity of Eugenol CTD PMID:15576237 copper(0) decreases expression ISO RGD:2475 6480464 Copper results in decreased expression of CYP2E1 mRNA CTD PMID:22465980 cortisol increases expression ISO RGD:2475 6480464 Hydrocortisone results in increased expression of CYP2E1 mRNA, Hydrocortisone results in increased expression of CYP2E1 protein CTD PMID:10476907 coumarin affects localization ISO RGD:2475 6480464 coumarin affects the localization of CYP2E1 protein CTD PMID:28803882 crocin-1 decreases activity ISO RGD:2475 6480464 crocin results in decreased activity of CYP2E1 protein CTD PMID:25899501 crocin-1 multiple interactions ISO RGD:2475 6480464 crocin inhibits the reaction [Carbon Tetrachloride results in increased activity of CYP2E1 protein] CTD PMID:25899501 curcumin affects expression ISO RGD:2475 6480464 Curcumin affects the expression of CYP2E1 protein CTD PMID:16805852 curcumin multiple interactions ISO RGD:10451 6480464 Curcumin inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA] more ... CTD PMID:30423402 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Acrylamide results in increased expression of CYP2E1 protein] CTD PMID:24508477 curcumin increases expression ISO RGD:2475 6480464 Curcumin results in increased expression of CYP2E1 mRNA CTD PMID:18539377 cyanides multiple interactions ISO RGD:10451 6480464 [CYP2E1 protein results in increased metabolism of methacrylonitrile] which results in increased abundance of Cyanides CTD PMID:15893539 cyanocob(III)alamin multiple interactions ISO RGD:10451 6480464 [Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein] CTD PMID:20118189 cyclohexanols multiple interactions ISO RGD:2475 6480464 [Diethylnitrosamine co-treated with Cyclohexanols] results in increased expression of CYP2E1 protein CTD PMID:17393424 cycloheximide multiple interactions EXP 6480464 (4-amidinophenyl)methanesulfonyl fluoride inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] more ... CTD PMID:8531136 , PMID:9143349 cycloheximide multiple interactions ISO RGD:2475 6480464 Cycloheximide inhibits the reaction [pyridine results in increased activity of CYP2E1 protein], Cycloheximide inhibits the reaction [pyridine results in increased expression of CYP2E1 protein] CTD PMID:1968335 cycloheximide increases degradation EXP 6480464 Cycloheximide results in increased degradation of CYP2E1 protein CTD PMID:9143349 cyclophosphamide increases metabolic processing ISO RGD:2475 6480464 CYP2E1 results in increased metabolism of Cyclophosphamide CTD PMID:20566340 cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of CYP2E1 mRNA CTD PMID:20106945 more ... cyclosporin A decreases expression ISO RGD:10451 6480464 Cyclosporine results in decreased expression of CYP2E1 mRNA CTD PMID:23830897 cyfluthrin increases activity ISO RGD:2475 6480464 cyfluthrin results in increased activity of CYP2E1 protein CTD PMID:23639246 cyhalothrin increases expression ISO RGD:2475 6480464 cyhalothrin results in increased expression of CYP2E1 mRNA CTD PMID:29727961 cylindrospermopsin decreases expression ISO RGD:10451 6480464 cylindrospermopsin results in decreased expression of CYP2E1 mRNA CTD PMID:20936652 cypermethrin decreases activity ISO RGD:10451 6480464 cypermethrin results in decreased activity of CYP2E1 protein CTD PMID:18420780 cypermethrin increases activity ISO RGD:2475 6480464 cypermethrin results in increased activity of CYP2E1 protein CTD PMID:25926273 cypermethrin multiple interactions ISO RGD:2475 6480464 [cypermethrin co-treated with propetamphos] results in increased activity of CYP2E1 protein CTD PMID:25926273 cypermethrin increases expression ISO RGD:2475 6480464 cypermethrin results in increased expression of CYP2E1 mRNA, cypermethrin results in increased expression of CYP2E1 protein CTD PMID:20815782 more ... cypermethrin multiple interactions EXP 6480464 cypermethrin inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:22634058 cypermethrin decreases activity EXP 6480464 cypermethrin results in decreased activity of CYP2E1 protein CTD PMID:22634058 cyproconazole multiple interactions ISO RGD:2475 6480464 [cyproconazole co-treated with epoxiconazole] results in increased expression of CYP2E1 mRNA CTD PMID:29038839 cyproconazole decreases expression EXP 6480464 cyproconazole results in decreased expression of CYP2E1 mRNA CTD PMID:29995386 D-penicillamine increases expression EXP 6480464 Penicillamine results in increased expression of CYP2E1 mRNA CTD PMID:22843330 daidzein decreases activity ISO RGD:10451 6480464 daidzein results in decreased activity of CYP2E1 protein CTD PMID:18420780 deoxycholic acid multiple interactions ISO RGD:2475 6480464 Deoxycholic Acid results in decreased expression of and results in decreased activity of CYP2E1 protein, Ursodeoxycholic Acid inhibits the reaction [Deoxycholic Acid results in decreased expression of and results in decreased activity of CYP2E1 protein] CTD PMID:10453939 desferrioxamine B multiple interactions ISO RGD:2475 6480464 Deferoxamine inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] CTD PMID:7710944 desipramine decreases activity EXP 6480464 Desipramine results in decreased activity of CYP2E1 protein CTD PMID:15135088 dexamethasone decreases expression ISO RGD:2475 6480464 Dexamethasone results in decreased expression of CYP2E1 protein CTD PMID:11181506 dexamethasone multiple interactions ISO RGD:2475 6480464 2-amino-4-(3 more ... CTD PMID:20501703 dexamethasone increases expression ISO RGD:10451 6480464 Dexamethasone results in increased expression of CYP2E1 mRNA CTD PMID:21041162 dexamethasone increases expression ISO RGD:2475 6480464 Dexamethasone results in increased expression of CYP2E1 mRNA, Dexamethasone results in increased expression of CYP2E1 protein CTD PMID:14618091 more ... dextran sulfate multiple interactions ISO RGD:2475 6480464 [Dextran Sulfate results in decreased activity of CYP2E1 protein] which results in decreased chemical synthesis of 6-hydroxychlorzoxazone CTD PMID:28438436 dextran sulfate decreases activity ISO RGD:2475 6480464 Dextran Sulfate results in decreased activity of CYP2E1 protein CTD PMID:28438436 dextromethorphan decreases activity ISO RGD:10451 6480464 Dextromethorphan results in decreased activity of CYP2E1 protein CTD PMID:18420780 diallyl disulfide decreases expression ISO RGD:10451 6480464 diallyl disulfide results in decreased expression of CYP2E1 protein CTD PMID:10774820 diallyl disulfide multiple interactions EXP 6480464 diallyl disulfide inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein] CTD PMID:19325051 diallyl disulfide decreases expression ISO RGD:2475 6480464 diallyl disulfide results in decreased expression of CYP2E1 protein CTD PMID:16000231 , PMID:24293383 diallyl disulfide decreases activity EXP 6480464 diallyl disulfide results in decreased activity of CYP2E1 protein CTD PMID:18339364 diallyl disulfide multiple interactions ISO RGD:10451 6480464 [diallyl disulfide results in decreased expression of CYP2E1 protein] which results in decreased metabolism of and results in decreased susceptibility to Trichloroethylene CTD PMID:10774820 Diallyl sulfide multiple interactions EXP 6480464 allyl sulfide inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]], allyl sulfide inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein] CTD PMID:12086689 , PMID:22138249 Diallyl sulfide increases expression ISO RGD:2475 6480464 allyl sulfide results in increased expression of CYP2E1 protein CTD PMID:8627517 Diallyl sulfide increases activity ISO RGD:2475 6480464 allyl sulfide results in increased activity of CYP2E1 protein CTD PMID:15046820 Diallyl sulfide decreases activity ISO RGD:2475 6480464 allyl sulfide results in decreased activity of CYP2E1 protein CTD PMID:30247689 , PMID:7956723 Diallyl sulfide decreases expression ISO RGD:2475 6480464 allyl sulfide results in decreased expression of CYP2E1 protein CTD PMID:16000231 more ... Diallyl sulfide multiple interactions ISO RGD:2475 6480464 allyl sulfide inhibits the reaction [1-bromopropane results in increased expression of CYP2E1] more ... CTD PMID:20116195 more ... Diallyl sulfide multiple interactions ISO RGD:10451 6480464 allyl sulfide inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA] more ... CTD PMID:21684301 more ... Diallyl sulfide decreases activity EXP 6480464 allyl sulfide results in decreased activity of CYP2E1 protein CTD PMID:15974642 more ... diallyl trisulfide decreases expression ISO RGD:2475 6480464 diallyl trisulfide results in decreased expression of CYP2E1 protein CTD PMID:28115069 diallyl trisulfide multiple interactions ISO RGD:2475 6480464 diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of and results in increased activity of CYP2E1 protein] CTD PMID:28115069 diarsenic trioxide affects expression EXP 6480464 Arsenic Trioxide affects the expression of CYP2E1 mRNA CTD PMID:17530438 dibenz[a,h]anthracene increases expression EXP 6480464 1 more ... CTD PMID:16269432 dibenziodolium multiple interactions ISO RGD:2475 6480464 diphenyleneiodonium inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein] CTD PMID:26880746 dibenziodolium decreases activity ISO RGD:2475 6480464 diphenyleneiodonium results in decreased activity of CYP2E1 protein CTD PMID:26880746 dibutyl phthalate decreases activity ISO RGD:2475 6480464 Dibutyl Phthalate results in decreased activity of CYP2E1 protein CTD PMID:27432241 dichloromethane multiple interactions ISO RGD:2475 6480464 3-xylene promotes the reaction [CYP2E1 protein results in increased metabolism of Methylene Chloride] more ... CTD PMID:8889796 dichloromethane increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of Methylene Chloride CTD PMID:1664256 dichloromethane increases metabolic processing ISO RGD:2475 6480464 CYP2E1 protein results in increased metabolism of Methylene Chloride CTD PMID:8889796 diclofenac decreases activity EXP 6480464 Diclofenac metabolite results in decreased activity of CYP2E1 protein CTD PMID:28960974 dicofol increases expression ISO RGD:2475 6480464 Dicofol results in increased expression of CYP2E1 protein CTD PMID:19595748 dicoumarol multiple interactions ISO RGD:2475 6480464 Dicumarol promotes the reaction [CYP2E1 protein results in increased reduction of tirapazamine] CTD PMID:7710944 diepoxybutane affects response to substance EXP 6480464 CYP2E1 gene polymorphism affects the susceptibility to diepoxybutane CTD PMID:15036125 diepoxybutane increases response to substance EXP 6480464 CYP2E1 gene polymorphism results in increased susceptibility to diepoxybutane CTD PMID:17078101 diethyldithiocarbamic acid decreases activity ISO RGD:2475 6480464 Ditiocarb results in decreased activity of CYP2E1 protein CTD PMID:1356728 diethyldithiocarbamic acid multiple interactions ISO RGD:2475 6480464 Ditiocarb inhibits the reaction [[Benzene results in increased expression of CYP2E1 protein] which results in increased metabolism of Benzene] more ... CTD PMID:1538706 more ... diethyldithiocarbamic acid decreases activity EXP 6480464 Ditiocarb results in decreased activity of CYP2E1 protein CTD PMID:15306208 more ... diethyldithiocarbamic acid multiple interactions EXP 6480464 Ditiocarb inhibits the reaction [CYP2E1 protein results in increased glutathionylation of Lamotrigine] more ... CTD PMID:10215755 more ... diethyldithiocarbamic acid multiple interactions ISO RGD:10451 6480464 [Ditiocarb co-treated with CYP2E1 gene mutant form] results in decreased metabolism of Styrene, [Ditiocarb results in decreased activity of CYP2E1 protein] which results in decreased oxidation of Benzene CTD PMID:12746132 , PMID:8560479 diethylstilbestrol increases expression ISO RGD:10451 6480464 Diethylstilbestrol results in increased expression of CYP2E1 mRNA CTD PMID:21041162 dihydrocapsaicin increases expression ISO RGD:2475 6480464 dihydrocapsaicin results in increased expression of CYP2E1 CTD PMID:22375877 dimethyl sulfoxide increases expression ISO RGD:2475 6480464 Dimethyl Sulfoxide results in increased expression of CYP2E1 protein CTD PMID:3113478 dimethyl sulfoxide increases activity ISO RGD:10451 6480464 Dimethyl Sulfoxide results in increased activity of CYP2E1 protein CTD PMID:17177172 dimethyl sulfoxide multiple interactions ISO RGD:2475 6480464 Dimethyl Sulfoxide binds to and results in increased expression of CYP2E1 protein more ... CTD PMID:1538706 more ... dimethyl sulfoxide increases expression EXP 6480464 Dimethyl Sulfoxide results in increased expression of CYP2E1 mRNA, Dimethyl Sulfoxide results in increased expression of CYP2E1 protein CTD PMID:30262279 , PMID:8074729 dimethyl sulfoxide multiple interactions EXP 6480464 Dimethyl Sulfoxide inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein], Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA]] CTD PMID:12147272 , PMID:9143349 dimethyl sulfoxide affects expression EXP 6480464 Dimethyl Sulfoxide affects the expression of CYP2E1 mRNA CTD PMID:12843640 dimethylmercury decreases expression ISO RGD:2475 6480464 dimethyl mercury results in decreased expression of CYP2E1 protein CTD PMID:21424224 dimethylmercury multiple interactions ISO RGD:2475 6480464 [Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP2E1 protein] CTD PMID:21424224 dioscin multiple interactions ISO RGD:10451 6480464 dioscin inhibits the reaction [Acetaminophen results in increased expression of and results in increased activity of CYP2E1 protein], dioscin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein] CTD PMID:22939915 , PMID:24146112 dioscin multiple interactions ISO RGD:2475 6480464 dioscin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein] CTD PMID:24146112 diosmetin decreases activity EXP 6480464 diosmetin results in decreased activity of CYP2E1 protein CTD PMID:28867436 diosmin multiple interactions ISO RGD:2475 6480464 Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased expression of CYP2E1 protein] CTD PMID:23665045 dioxygen decreases expression EXP 6480464 Oxygen deficiency results in decreased expression of CYP2E1 mRNA CTD PMID:19695866 dioxygen multiple interactions ISO RGD:2475 6480464 [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP2E1 mRNA more ... CTD PMID:26747958 dipropyl disulfide decreases activity EXP 6480464 n-propyl disulfide results in decreased activity of CYP2E1 protein CTD PMID:18339364 dipropyl phthalate decreases activity ISO RGD:2475 6480464 di-n-propylphthalate results in decreased activity of CYP2E1 protein CTD PMID:27432241 disulfiram multiple interactions EXP 6480464 [Disulfiram results in decreased activity of CYP2E1 protein] which affects the activity of Styrene more ... CTD PMID:10805064 more ... disulfiram decreases activity EXP 6480464 Disulfiram results in decreased activity of CYP2E1 protein CTD PMID:1664256 more ... disulfiram multiple interactions ISO RGD:10451 6480464 [Disulfiram results in decreased activity of CYP2E1 protein] which affects the activity of Styrene CTD PMID:20470765 disulfiram decreases expression ISO RGD:2475 6480464 Disulfiram results in decreased expression of CYP2E1 mRNA, Disulfiram results in decreased expression of CYP2E1 protein CTD PMID:9393675 disulfiram decreases activity ISO RGD:2475 6480464 Disulfiram results in decreased activity of CYP2E1 protein CTD PMID:9393675 disulfiram multiple interactions ISO RGD:2475 6480464 Disulfiram binds to and results in decreased activity of CYP2E1 protein CTD PMID:18754103 dodecanoic acid increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of lauric acid CTD PMID:12464242 dopamine decreases activity ISO RGD:10451 6480464 Dopamine results in decreased activity of CYP2E1 protein CTD PMID:18420780 doxorubicin increases expression ISO RGD:10451 6480464 Doxorubicin results in increased expression of CYP2E1 mRNA CTD PMID:26873546 dronedarone increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of dronedarone CTD PMID:29616291 ebselen multiple interactions ISO RGD:2475 6480464 ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA] CTD PMID:11903743 elemental selenium multiple interactions ISO RGD:2475 6480464 [Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP2E1 protein] CTD PMID:21424224 ellipticine increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of ellipticine CTD PMID:22917556 emamectin benzoate multiple interactions ISO RGD:10451 6480464 Plant Oils inhibits the reaction [emamectin benzoate results in increased expression of CYP2E1 mRNA] CTD PMID:29268245 emamectin benzoate increases expression ISO RGD:10451 6480464 emamectin benzoate results in increased expression of CYP2E1 mRNA CTD PMID:29268245 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of CYP2E1 mRNA, Endosulfan results in decreased expression of CYP2E1 protein CTD PMID:26159488 , PMID:28673560 endosulfan increases expression ISO RGD:10451 6480464 Endosulfan analog results in increased expression of CYP2E1 mRNA, Endosulfan results in increased expression of CYP2E1 mRNA CTD PMID:29702342 endosulfan increases expression ISO RGD:2475 6480464 Endosulfan results in increased expression of CYP2E1 mRNA CTD PMID:29391264 endosulfan multiple interactions EXP 6480464 [Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of CYP2E1 mRNA more ... CTD PMID:26159488 , PMID:28673560 enfuvirtide affects activity EXP 6480464 enfuvirtide affects the activity of CYP2E1 protein CTD PMID:15656696 epoxiconazole multiple interactions ISO RGD:2475 6480464 [cyproconazole co-treated with epoxiconazole] results in increased expression of CYP2E1 mRNA CTD PMID:29038839 Estragole increases hydroxylation EXP 6480464 CYP2E1 protein results in increased hydroxylation of estragole CTD PMID:19920071 ethambutol decreases activity EXP 6480464 Ethambutol results in decreased activity of CYP2E1 protein CTD PMID:24910189 ethambutol multiple interactions ISO RGD:2475 6480464 [Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein more ... CTD PMID:27919644 ethanol multiple interactions ISO RGD:2475 6480464 [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP2E1 mRNA more ... CTD PMID:15763544 more ... ethanol decreases activity ISO RGD:2475 6480464 Ethanol results in decreased activity of CYP2E1 protein CTD PMID:17299812 ethanol increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to Ethanol CTD PMID:28131861 ethanol multiple interactions EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:10573527 more ... ethanol decreases expression ISO RGD:10451 6480464 Ethanol results in decreased expression of CYP2E1 mRNA CTD PMID:28119953 ethanol increases expression ISO RGD:2475 6480464 Ethanol results in increased expression of CYP2E1 mRNA, Ethanol results in increased expression of CYP2E1 protein CTD PMID:19609968 more ... ethanol increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Ethanol CTD PMID:10573527 more ... ethanol affects activity EXP 6480464 Ethanol affects the activity of CYP2E1 protein CTD PMID:22530035 ethanol increases oxidation ISO RGD:10451 6480464 CYP2E1 protein results in increased oxidation of Ethanol CTD PMID:22552773 ethanol increases activity ISO RGD:2475 6480464 Ethanol results in increased activity of CYP2E1 protein CTD PMID:15998439 more ... ethanol affects response to substance EXP 6480464 CYP2E1 gene polymorphism affects the susceptibility to Ethanol CTD PMID:20171022 ethanol increases expression EXP 6480464 Ethanol results in increased expression of CYP2E1 more ... CTD PMID:17590308 more ... ethanol increases response to substance ISO RGD:2475 6480464 CYP2E1 protein results in increased susceptibility to Ethanol CTD PMID:21130154 ethanol increases metabolic processing ISO RGD:2475 6480464 CYP2E1 protein results in increased metabolism of Ethanol CTD PMID:11147839 more ... ethanol increases activity EXP 6480464 Ethanol results in increased activity of CYP2E1 protein CTD PMID:11212141 , PMID:8074729 ethanol affects activity ISO RGD:2475 6480464 Ethanol affects the activity of CYP2E1 protein CTD PMID:17533807 ethanol increases activity ISO RGD:10451 6480464 Ethanol results in increased activity of CYP2E1 protein CTD PMID:10667633 , PMID:15920153 ethanol multiple interactions ISO RGD:10451 6480464 [AQP4 protein affects the susceptibility to Ethanol] which affects the expression of CYP2E1 mRNA more ... CTD PMID:15582191 more ... ethanol increases response to substance EXP 6480464 CYP2E1 protein results in increased susceptibility to Ethanol CTD PMID:8798623 ethanol increases expression ISO RGD:10451 6480464 Ethanol results in increased expression of CYP2E1 more ... CTD PMID:11515535 more ... ethene increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of ethylene CTD PMID:21785163 ethene decreases activity ISO RGD:2475 6480464 ethylene results in decreased activity of CYP2E1 protein CTD PMID:15141094 ethene multiple interactions ISO RGD:10451 6480464 [CYP2E1 protein results in increased metabolism of ethylene] which results in increased abundance of Ethylene Oxide CTD PMID:21785163 ethosuximide affects metabolic processing ISO RGD:2475 6480464 CYP2E1 protein affects the metabolism of Ethosuximide CTD PMID:1438522 ethyl methanesulfonate decreases expression EXP 6480464 Ethyl Methanesulfonate results in decreased expression of CYP2E1 mRNA CTD PMID:23649840 ethylbenzene multiple interactions ISO RGD:2475 6480464 ethylbenzene results in increased expression of and results in increased activity of CYP2E1 protein, GH1 protein inhibits the reaction [ethylbenzene results in increased expression of CYP2E1 protein] CTD PMID:11884239 ethylbenzene increases expression ISO RGD:2475 6480464 ethylbenzene results in increased expression of CYP2E1 mRNA, ethylbenzene results in increased expression of CYP2E1 protein CTD PMID:11884239 more ... ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions EXP 6480464 Egtazic Acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] CTD PMID:9143349 ethylenediaminetetraacetic acid multiple interactions EXP 6480464 Edetic Acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] CTD PMID:9143349 ethylparaben decreases activity ISO RGD:2475 6480464 ethyl-p-hydroxybenzoate results in decreased activity of CYP2E1 protein CTD PMID:27432241 eugenol multiple interactions ISO RGD:2475 6480464 Eugenol inhibits the reaction [Thioacetamide results in increased expression of CYP2E1 protein] CTD PMID:20036707 eugenol multiple interactions EXP 6480464 [CYP2E1 protein co-treated with Copper] results in increased activity of Eugenol CTD PMID:15576237 farnesol increases activity ISO RGD:2475 6480464 Farnesol results in increased activity of CYP2E1 protein CTD PMID:15840382 farnesol multiple interactions EXP 6480464 [Farnesol analog co-treated with Oleic Acid] results in increased expression of CYP2E1 mRNA, Farnesol analog inhibits the reaction [Oleic Acid results in increased expression of CYP2E1 mRNA] CTD PMID:30611723 farnesol decreases expression EXP 6480464 Farnesol analog results in decreased expression of CYP2E1 mRNA, Farnesol results in decreased expression of CYP2E1 mRNA CTD PMID:30611723 felbamate decreases expression ISO RGD:2475 6480464 felbamate results in decreased expression of CYP2E1 mRNA CTD PMID:17381134 fenarimol multiple interactions ISO RGD:10451 6480464 [fenarimol co-treated with acephate] affects the expression of CYP2E1 protein more ... CTD PMID:17686559 fenitrothion multiple interactions EXP 6480464 Fenitrothion inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:22634058 fenitrothion decreases activity EXP 6480464 Fenitrothion results in decreased activity of CYP2E1 protein CTD PMID:22634058 fenofibrate increases expression ISO RGD:2475 6480464 Fenofibrate results in increased expression of CYP2E1 mRNA CTD PMID:19118567 fenvalerate multiple interactions EXP 6480464 fenvalerate inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:22634058 fenvalerate decreases activity EXP 6480464 fenvalerate results in decreased activity of CYP2E1 protein CTD PMID:22634058 fipronil increases expression ISO RGD:2475 6480464 fipronil results in increased expression of CYP2E1 mRNA CTD PMID:23962444 fipronil decreases expression EXP 6480464 fipronil results in decreased expression of CYP2E1 mRNA CTD PMID:27091632 fipronil multiple interactions EXP 6480464 [fipronil co-treated with DEET] results in decreased expression of CYP2E1 mRNA CTD PMID:27091632 flavonoids multiple interactions ISO RGD:10451 6480464 Flavonoids inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 protein] CTD PMID:23279844 fluoranthene increases expression EXP 6480464 fluoranthene results in increased expression of CYP2E1 mRNA CTD PMID:16269432 fluoroethene multiple interactions EXP 6480464 [fomepizole results in decreased activity of CYP2E1 protein] which results in decreased metabolism of vinyl fluoride CTD PMID:9073601 fluoroethene multiple interactions ISO RGD:2475 6480464 [Ethanol results in increased activity of CYP2E1 protein] which results in increased metabolism of vinyl fluoride, [fomepizole results in decreased activity of CYP2E1 protein] which results in decreased uptake of vinyl fluoride CTD PMID:9073601 fluoroethene multiple interactions ISO RGD:10451 6480464 [fomepizole results in decreased activity of CYP2E1 protein] which results in decreased uptake of vinyl fluoride CTD PMID:9073601 fluoroethene affects oxidation ISO RGD:10451 6480464 CYP2E1 protein affects the oxidation of vinyl fluoride CTD PMID:9073601 fluphenazine decreases activity EXP 6480464 Fluphenazine results in decreased activity of CYP2E1 protein CTD PMID:15135088 folic acid multiple interactions ISO RGD:10451 6480464 [Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein], [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CYP2E1 mRNA CTD PMID:20118189 , PMID:22872676 fomepizole multiple interactions EXP 6480464 [fomepizole results in decreased activity of CYP2E1 protein] which results in decreased metabolism of vinyl fluoride more ... CTD PMID:11409937 more ... fomepizole decreases activity EXP 6480464 fomepizole results in decreased activity of CYP2E1 protein CTD PMID:21336516 more ... fomepizole increases expression ISO RGD:2475 6480464 fomepizole results in increased expression of CYP2E1 protein CTD PMID:3113478 , PMID:3782137 fomepizole increases activity ISO RGD:2475 6480464 fomepizole results in increased activity of CYP2E1 protein CTD PMID:3782137 fomepizole multiple interactions ISO RGD:10451 6480464 [fomepizole results in decreased activity of CYP2E1 protein] which results in decreased uptake of vinyl fluoride CTD PMID:9073601 fomepizole multiple interactions ISO RGD:2475 6480464 [fomepizole results in decreased activity of CYP2E1 protein] which results in decreased uptake of vinyl fluoride, fomepizole promotes the reaction [CYP2E1 protein results in increased metabolism of methylformamide] CTD PMID:1538706 , PMID:9073601 fomepizole increases expression EXP 6480464 fomepizole results in increased expression of CYP2E1 protein CTD PMID:8074729 fructose increases expression ISO RGD:10451 6480464 Fructose results in increased expression of CYP2E1 protein CTD PMID:26858005 fructose decreases expression ISO RGD:10451 6480464 Fructose results in decreased expression of CYP2E1 protein CTD PMID:28257781 fructose multiple interactions ISO RGD:10451 6480464 Ethanol promotes the reaction [Fructose results in increased expression of CYP2E1 protein] CTD PMID:26858005 fulvestrant multiple interactions EXP 6480464 fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of CYP2E1 mRNA] CTD PMID:29362861 fumaraldehyde multiple interactions ISO RGD:2475 6480464 1-phenylimidazole inhibits the reaction [[[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde] more ... CTD PMID:21842885 fumonisin B1 decreases expression ISO RGD:10451 6480464 fumonisin B1 results in decreased expression of CYP2E1 mRNA CTD PMID:16221962 furan decreases expression ISO RGD:2475 6480464 furan results in decreased expression of CYP2E1 mRNA, furan results in decreased expression of CYP2E1 protein CTD PMID:15120968 , PMID:20124500 furan multiple interactions ISO RGD:2475 6480464 1-phenylimidazole inhibits the reaction [[[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde] more ... CTD PMID:21842885 gabapentin decreases expression ISO RGD:2475 6480464 gabapentin results in decreased expression of CYP2E1 mRNA CTD PMID:17381134 gadolinium trichloride multiple interactions ISO RGD:2475 6480464 gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2E1 mRNA], gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2E1 protein] CTD PMID:18202523 gamma-hexachlorocyclohexane increases activity ISO RGD:2475 6480464 Hexachlorocyclohexane results in increased activity of CYP2E1 protein CTD PMID:12842176 , PMID:14631868 gamma-hexachlorocyclohexane increases expression ISO RGD:2475 6480464 Hexachlorocyclohexane results in increased expression of CYP2E1 mRNA, Hexachlorocyclohexane results in increased expression of CYP2E1 protein CTD PMID:12842176 more ... gamma-hexachlorocyclohexane decreases response to substance EXP 6480464 CYP2E1 protein results in decreased susceptibility to Hexachlorocyclohexane CTD PMID:21458603 gamma-hexachlorocyclohexane decreases expression EXP 6480464 Hexachlorocyclohexane results in decreased expression of CYP2E1 mRNA CTD PMID:20035023 genistein multiple interactions ISO RGD:2475 6480464 [Genistein co-treated with Methoxychlor] results in increased expression of CYP2E1 mRNA more ... CTD PMID:21782745 , PMID:23274713 genistein multiple interactions ISO RGD:10451 6480464 Genistein inhibits the reaction [Acetaminophen results in increased activity of CYP2E1 protein] CTD PMID:23333575 gentamycin multiple interactions ISO RGD:2475 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2E1 mRNA CTD PMID:30545405 geranial multiple interactions EXP 6480464 [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral, [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite CTD PMID:18824010 geraniol multiple interactions EXP 6480464 [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral more ... CTD PMID:18824010 geraniol multiple interactions ISO RGD:2475 6480464 geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CYP2E1 protein] CTD PMID:26695085 ginsenoside Rg1 multiple interactions ISO RGD:10451 6480464 ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA] CTD PMID:29964319 glafenine decreases expression ISO RGD:2475 6480464 Glafenine results in decreased expression of CYP2E1 mRNA CTD PMID:24136188 glutathione multiple interactions EXP 6480464 [CYP2E1 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 2'-(glutathion-S-yl)-deschlorodiclofenac more ... CTD PMID:10573527 more ... glutathione multiple interactions ISO RGD:10451 6480464 Glutathione inhibits the reaction [Alcohols results in increased expression of CYP2E1 protein] CTD PMID:28803762 glutathione multiple interactions ISO RGD:2475 6480464 1-phenylimidazole inhibits the reaction [[[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde] more ... CTD PMID:21842885 , PMID:8211999 glycerol multiple interactions EXP 6480464 Glycerol inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] CTD PMID:9143349 glycine betaine multiple interactions ISO RGD:10451 6480464 [Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein] CTD PMID:20118189 glycine betaine multiple interactions EXP 6480464 Betaine promotes the reaction [Ethanol results in increased expression of CYP2E1] CTD PMID:21352821 glycyrrhetinate multiple interactions ISO RGD:2475 6480464 [brucine co-treated with Glycyrrhetinic Acid] results in decreased activity of CYP2E1 protein CTD PMID:21800547 glycyrrhetinic acid multiple interactions ISO RGD:2475 6480464 [brucine co-treated with Glycyrrhetinic Acid] results in decreased activity of CYP2E1 protein CTD PMID:21800547 glyphosate increases methylation ISO RGD:2475 6480464 glyphosate results in increased methylation of CYP2E1 gene CTD PMID:31011160 GW 4064 multiple interactions EXP 6480464 [GW 4064 co-treated with Oleic Acid] results in decreased expression of CYP2E1 mRNA CTD PMID:30611723 GW 4064 decreases expression EXP 6480464 GW 4064 results in decreased expression of CYP2E1 mRNA CTD PMID:30611723 halothane multiple interactions EXP 6480464 Disulfiram inhibits the reaction [CYP2E1 protein results in increased oxidation of Halothane] CTD PMID:10805064 halothane increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of Halothane CTD PMID:10805064 halothane affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of Halothane CTD PMID:9103523 halothane increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Halothane CTD PMID:11684365 , PMID:12464242 halothane increases response to substance ISO RGD:2475 6480464 CYP2E1 protein results in increased susceptibility to Halothane CTD PMID:12803597 hemin multiple interactions ISO RGD:2475 6480464 Hemin inhibits the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased expression of CYP2E1 mRNA] more ... CTD PMID:26747958 hemin multiple interactions EXP 6480464 Hemin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein] CTD PMID:19325051 hesperetin multiple interactions ISO RGD:2475 6480464 hesperetin inhibits the reaction [1, 2-Dimethylhydrazine results in increased activity of CYP2E1 protein] CTD PMID:19497424 hexachlorobenzene decreases expression ISO RGD:2475 6480464 Hexachlorobenzene results in decreased expression of CYP2E1 mRNA CTD PMID:15159207 hexachlorobenzene increases expression ISO RGD:2475 6480464 Hexachlorobenzene results in increased expression of CYP2E1 protein CTD PMID:10696772 hexadecanoic acid multiple interactions ISO RGD:2475 6480464 [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA] more ... CTD PMID:26854922 hexane affects response to substance EXP 6480464 CYP2E1 gene polymorphism affects the susceptibility to n-hexane CTD PMID:16484137 hexane multiple interactions ISO RGD:2475 6480464 diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of and results in increased activity of CYP2E1 protein], n-hexane results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:28115069 hexane increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of n-hexane CTD PMID:11201664 hexane increases hydroxylation EXP 6480464 CYP2E1 protein results in increased hydroxylation of n-hexane CTD PMID:16484137 hydrazine increases activity ISO RGD:2475 6480464 hydrazine results in increased activity of CYP2E1 protein CTD PMID:15132840 hydrogen peroxide increases abundance EXP 6480464 CYP2E1 protein results in increased abundance of Hydrogen Peroxide CTD PMID:25061110 hydroquinone multiple interactions EXP 6480464 [CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of hydroquinone more ... CTD PMID:15051535 , PMID:30567741 hydroquinone increases expression EXP 6480464 hydroquinone results in increased expression of CYP2E1 mRNA, hydroquinone results in increased expression of CYP2E1 protein CTD PMID:30567741 hydroquinone multiple interactions ISO RGD:2475 6480464 [CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone more ... CTD PMID:8211999 Hypaconitine increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of hypaconitine CTD PMID:21550385 imidazoles multiple interactions ISO RGD:2475 6480464 Imidazoles inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:21600194 indole-3-methanol decreases activity EXP 6480464 indole-3-carbinol results in decreased activity of CYP2E1 protein CTD PMID:17582584 indometacin decreases expression ISO RGD:2475 6480464 Indomethacin results in decreased expression of CYP2E1 mRNA CTD PMID:16771604 iron(III) citrate increases expression EXP 6480464 ferric citrate results in increased expression of CYP2E1 mRNA CTD PMID:24025710 iron(III) citrate multiple interactions EXP 6480464 Alcohols inhibits the reaction [ferric citrate results in increased expression of CYP2E1 mRNA], ferric citrate inhibits the reaction [Alcohols results in increased expression of CYP2E1 mRNA] CTD PMID:24025710 iron(III) nitrilotriacetate multiple interactions EXP 6480464 [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT18 protein more ... CTD PMID:12086689 more ... isatin increases expression EXP 6480464 Isatin results in increased expression of CYP2E1 mRNA CTD PMID:15056799 isobutyronitrile increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to isobutyronitrile CTD PMID:22051853 isoliquiritigenin multiple interactions ISO RGD:2475 6480464 isoliquiritigenin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA], isoliquiritigenin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein] CTD PMID:25450236 isoniazide affects response to substance EXP 6480464 CYP2E1 gene polymorphism affects the susceptibility to Isoniazid, CYP2E1 gene SNP affects the susceptibility to Isoniazid CTD PMID:12668988 , PMID:20485159 isoniazide increases response to substance EXP 6480464 CYP2E1 protein results in increased susceptibility to Isoniazid CTD PMID:28762043 isoniazide multiple interactions EXP 6480464 GSTM1 protein inhibits the reaction [CYP2E1 protein results in increased susceptibility to Isoniazid] CTD PMID:28762043 isoniazide increases activity ISO RGD:2475 6480464 Isoniazid results in increased activity of CYP2E1 protein CTD PMID:12458634 more ... isoniazide increases expression ISO RGD:10451 6480464 Isoniazid results in increased expression of CYP2E1 mRNA CTD PMID:22342832 isoniazide multiple interactions ISO RGD:10451 6480464 Berberine inhibits the reaction [Isoniazid results in increased expression of CYP2E1 mRNA] CTD PMID:22342832 isoniazide increases expression ISO RGD:2475 6480464 Isoniazid results in increased expression of CYP2E1 more ... CTD PMID:11752103 more ... isoniazide increases expression EXP 6480464 Isoniazid results in increased expression of CYP2E1 protein CTD PMID:8074729 isoniazide multiple interactions ISO RGD:2475 6480464 2-(allylthio)pyrazine inhibits the reaction [Isoniazid results in increased expression of CYP2E1 protein] more ... CTD PMID:12458634 more ... isoniazide increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Isoniazid CTD PMID:17950035 isoprenaline affects expression ISO RGD:2475 6480464 Isoproterenol affects the expression of CYP2E1 mRNA CTD PMID:18725507 isoproturon decreases activity EXP 6480464 isoproturon results in decreased activity of CYP2E1 protein CTD PMID:22634058 isoproturon multiple interactions EXP 6480464 isoproturon inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:22634058 isoquinolines multiple interactions ISO RGD:2475 6480464 Isoquinolines inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:21600194 ivermectin decreases activity ISO RGD:10451 6480464 Ivermectin results in decreased activity of CYP2E1 protein CTD PMID:18420780 kaempferol multiple interactions ISO RGD:10451 6480464 kaempferol inhibits the reaction [propacetamol results in increased expression of CYP2E1 protein] CTD PMID:29574133 kahweol decreases activity ISO RGD:10451 6480464 kahweol results in decreased activity of CYP2E1 protein CTD PMID:17590492 kalopanaxsaponin A decreases activity ISO RGD:10451 6480464 alpha-hederin results in decreased activity of CYP2E1 protein CTD PMID:9861456 ketamine increases expression ISO RGD:2475 6480464 Ketamine results in increased expression of CYP2E1 protein CTD PMID:16076768 ketoconazole decreases activity EXP 6480464 Ketoconazole results in decreased activity of CYP2E1 protein CTD PMID:15618748 kojic acid multiple interactions ISO RGD:2475 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2E1 mRNA CTD PMID:18544905 L-ascorbic acid decreases activity EXP 6480464 Ascorbic Acid results in decreased activity of CYP2E1 protein CTD PMID:17512695 L-ascorbic acid multiple interactions ISO RGD:2475 6480464 Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of CYP2E1 mRNA], Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of CYP2E1 protein] CTD PMID:31585129 L-methionine multiple interactions ISO RGD:10451 6480464 [Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein] more ... CTD PMID:18952117 more ... L-methionine multiple interactions ISO RGD:2475 6480464 [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein] more ... CTD PMID:26695085 , PMID:27919644 lamotrigine increases glutathionylation EXP 6480464 CYP2E1 protein results in increased glutathionylation of lamotrigine CTD PMID:19961160 lamotrigine multiple interactions EXP 6480464 Ditiocarb inhibits the reaction [CYP2E1 protein results in increased glutathionylation of lamotrigine] CTD PMID:19961160 leupeptin multiple interactions EXP 6480464 leupeptin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] CTD PMID:9143349 linoleic acid decreases activity EXP 6480464 Linoleic Acid results in decreased activity of CYP2E1 protein CTD PMID:16978661 lipopolysaccharide multiple interactions EXP 6480464 [usnic acid co-treated with Lipopolysaccharides] results in decreased expression of CYP2E1 mRNA, Lipopolysaccharides affects the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine] CTD PMID:16235733 , PMID:22777745 lipopolysaccharide multiple interactions ISO RGD:10451 6480464 [AQP4 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of CYP2E1 mRNA CTD PMID:20615459 liquiritin multiple interactions ISO RGD:2475 6480464 [brucine co-treated with liquiritin] results in decreased activity of CYP2E1 protein CTD PMID:21800547 lithocholic acid decreases activity ISO RGD:10451 6480464 Lithocholic Acid results in decreased activity of CYP2E1 protein CTD PMID:18420780 LSM-2726 decreases activity ISO RGD:10451 6480464 Dextromethorphan results in decreased activity of CYP2E1 protein CTD PMID:18420780 luteolin multiple interactions ISO RGD:10451 6480464 Luteolin inhibits the reaction [Cisplatin results in increased expression of CYP2E1 protein] CTD PMID:23770416 LY 364947 increases expression ISO RGD:10451 6480464 Ly-364947 results in increased expression of CYP2E1 mRNA CTD PMID:25566828 LY 364947 multiple interactions ISO RGD:10451 6480464 Ly-364947 inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA], Ly-364947 inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein] CTD PMID:25566828 LY294002 increases expression ISO RGD:2475 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of CYP2E1 mRNA CTD PMID:11306697 lycopene multiple interactions ISO RGD:10451 6480464 lycopene inhibits the reaction [Atrazine results in increased expression of CYP2E1 mRNA] CTD PMID:26775023 m-tolualdehyde decreases activity ISO RGD:2475 6480464 3-methylbenzaldehyde results in decreased activity of CYP2E1 protein CTD PMID:12791539 m-xylene affects activity ISO RGD:2475 6480464 3-xylene affects the activity of CYP2E1 protein CTD PMID:15204773 , PMID:8598570 m-xylene multiple interactions EXP 6480464 Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 3-xylene] CTD PMID:8558417 m-xylene increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of 3-xylene CTD PMID:8558417 m-xylene decreases activity ISO RGD:2475 6480464 3-xylene results in decreased activity of CYP2E1 protein CTD PMID:12791539 m-xylene increases hydrolysis EXP 6480464 CYP2E1 protein results in increased hydrolysis of 3-xylene CTD PMID:10353308 m-xylene increases activity ISO RGD:2475 6480464 3-xylene results in increased activity of CYP2E1 protein CTD PMID:8889796 m-xylene multiple interactions ISO RGD:2475 6480464 3-xylene promotes the reaction [CYP2E1 protein results in increased metabolism of Methylene Chloride] CTD PMID:8889796 m-xylene increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of 3-xylene CTD PMID:17156750 m-xylene increases expression ISO RGD:2475 6480464 3-xylene results in increased expression of CYP2E1 protein CTD PMID:8517779 malathion decreases activity EXP 6480464 Malathion results in decreased activity of CYP2E1 protein CTD PMID:22634058 malathion multiple interactions EXP 6480464 Malathion inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:22634058 mandelic acid multiple interactions EXP 6480464 CYP2E1 polymorphism affects the metabolism of [mandelic acid co-treated with phenylglyoxylic acid] CTD PMID:25562543 maneb decreases activity ISO RGD:2475 6480464 Maneb results in decreased activity of CYP2E1 protein CTD PMID:11043497 maneb increases expression ISO RGD:2475 6480464 Maneb results in increased expression of CYP2E1 mRNA, Maneb results in increased expression of CYP2E1 protein CTD PMID:20888808 , PMID:23159886 maneb multiple interactions ISO RGD:2475 6480464 [Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein more ... CTD PMID:23159886 maneb increases activity ISO RGD:2475 6480464 Maneb results in increased activity of CYP2E1 protein CTD PMID:20888808 maneb multiple interactions ISO RGD:10451 6480464 [Maneb co-treated with Paraquat] results in increased expression of CYP2E1 mRNA more ... CTD PMID:16510128 , PMID:20964710 mangiferin decreases activity ISO RGD:2475 6480464 mangiferin results in decreased activity of CYP2E1 protein CTD PMID:18053976 melatonin multiple interactions ISO RGD:2475 6480464 Melatonin inhibits the reaction [Benzene results in increased activity of CYP2E1 protein] CTD PMID:20338863 melatonin multiple interactions ISO RGD:10451 6480464 Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased activity of CYP2E1 protein], Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA] CTD PMID:20964710 menadione decreases expression ISO RGD:10451 6480464 Vitamin K 3 results in decreased expression of CYP2E1 mRNA CTD PMID:25270620 mephenytoin decreases activity ISO RGD:10451 6480464 Mephenytoin results in decreased activity of CYP2E1 protein CTD PMID:18420780 mercury dichloride decreases expression ISO RGD:2475 6480464 Mercuric Chloride results in decreased expression of CYP2E1 mRNA CTD PMID:22792809 metformin increases expression ISO RGD:10451 6480464 Metformin results in increased expression of CYP2E1 mRNA CTD PMID:22342832 methamphetamine affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of Methamphetamine metabolite CTD PMID:16038959 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of CYP2E1 mRNA CTD PMID:28935588 methapyrilene decreases expression ISO RGD:2475 6480464 Methapyrilene results in decreased expression of CYP2E1 mRNA CTD PMID:30467583 methoxsalen decreases activity ISO RGD:2475 6480464 Methoxsalen results in decreased activity of CYP2E1 protein CTD PMID:15879494 methoxsalen decreases activity ISO RGD:10451 6480464 Methoxsalen results in decreased activity of CYP2E1 protein CTD PMID:18420780 methoxychlor multiple interactions ISO RGD:2475 6480464 [Genistein co-treated with Methoxychlor] results in increased expression of CYP2E1 mRNA, Methoxychlor results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:12919727 , PMID:21782745 methoxychlor increases expression ISO RGD:2475 6480464 Methoxychlor results in increased expression of CYP2E1 mRNA CTD PMID:21782745 methoxychlor decreases activity ISO RGD:10451 6480464 Methoxychlor results in decreased activity of CYP2E1 protein CTD PMID:18420780 methoxyflurane increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Methoxyflurane CTD PMID:7879937 methyltestosterone multiple interactions EXP 6480464 [Methyltestosterone co-treated with Cholic Acids] affects the expression of CYP2E1 mRNA CTD PMID:27344345 metronidazole multiple interactions ISO RGD:2475 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2E1 mRNA CTD PMID:30545405 microcystin-LR multiple interactions ISO RGD:10451 6480464 allyl sulfide inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA] more ... CTD PMID:21684301 microcystin-LR increases expression ISO RGD:10451 6480464 cyanoginosin LR results in increased expression of CYP2E1 mRNA, cyanoginosin LR results in increased expression of CYP2E1 protein CTD PMID:21684301 midazolam increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Midazolam CTD PMID:17590308 mirex decreases expression ISO RGD:2475 6480464 Mirex results in decreased expression of CYP2E1 protein CTD PMID:3113478 Monobutylphthalate decreases activity ISO RGD:2475 6480464 monobutyl phthalate results in decreased activity of CYP2E1 protein CTD PMID:27432241 monocrotophos increases expression ISO RGD:2475 6480464 Monocrotophos results in increased expression of CYP2E1 protein CTD PMID:21445290 monocrotophos multiple interactions EXP 6480464 [Monocrotophos co-treated with Cimetidine] results in increased expression of CYP2E1 protein more ... CTD PMID:22733800 monocrotophos increases expression EXP 6480464 Monocrotophos results in increased expression of CYP2E1 mRNA, Monocrotophos results in increased expression of CYP2E1 protein CTD PMID:22733800 monocrotophos increases activity EXP 6480464 Monocrotophos results in increased activity of CYP2E1 protein CTD PMID:22733800 muconic acid multiple interactions EXP 6480464 [CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of muconic acid CTD PMID:15051535 myricetin decreases activity EXP 6480464 myricetin results in decreased activity of CYP2E1 protein CTD PMID:29753067 myricitrin multiple interactions ISO RGD:10451 6480464 myricitrin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein] CTD PMID:25656916 N'-(2,4-dimethylphenyl)-N-methylformamidine increases expression ISO RGD:2475 6480464 U 40481 results in increased expression of CYP2E1 protein CTD PMID:31029719 N,N-diethyl-m-toluamide increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of DEET CTD PMID:11854147 N,N-diethyl-m-toluamide multiple interactions EXP 6480464 [fipronil co-treated with DEET] results in decreased expression of CYP2E1 mRNA CTD PMID:27091632 N,N-diisopropyltryptamine multiple interactions EXP 6480464 [N, N-diisopropyltryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone CTD PMID:26599973 N,N-diisopropyltryptamine decreases activity EXP 6480464 N, N-diisopropyltryptamine analog results in decreased activity of CYP2E1 protein CTD PMID:26599973 N,N-dimethylformamide affects metabolic processing EXP 6480464 CYP2E1 protein polymorphism affects the metabolism of Dimethylformamide CTD PMID:11305777 N,N-dimethylformamide increases expression EXP 6480464 Dimethylformamide results in increased expression of CYP2E1 protein CTD PMID:29984871 N,N-dimethylformamide increases abundance EXP 6480464 CYP2E1 polymorphism results in increased abundance of Dimethylformamide metabolite CTD PMID:31501917 N,N-dimethylformamide multiple interactions ISO RGD:10451 6480464 CYP2E1 protein affects the reaction [Dimethylformamide results in increased activity of GPT protein], CYP2E1 protein affects the reaction [Dimethylformamide results in increased expression of HSP90B1 protein] CTD PMID:31501917 N,N-dimethylformamide increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to Dimethylformamide CTD PMID:31501917 N,N-dimethylformamide increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Dimethylformamide CTD PMID:9817075 N,N-dimethylformamide affects metabolic processing ISO RGD:2475 6480464 CYP2E1 protein affects the metabolism of Dimethylformamide CTD PMID:15772367 N,N-dimethylformamide increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of Dimethylformamide CTD PMID:10207612 N-acetyl-1,4-benzoquinone imine multiple interactions ISO RGD:10451 6480464 CYP2E1 protein results in increased chemical synthesis of and results in increased abundance of N-acetyl-4-benzoquinoneimine CTD PMID:19679878 N-acetyl-1,4-benzoquinone imine increases abundance EXP 6480464 CYP2E1 protein results in increased abundance of N-acetyl-4-benzoquinoneimine CTD PMID:24661219 N-acetyl-1,4-benzoquinone imine increases chemical synthesis ISO RGD:2475 6480464 CYP2E1 results in increased chemical synthesis of N-acetyl-4-benzoquinoneimine CTD PMID:20566340 N-acetyl-1,4-benzoquinone imine increases chemical synthesis EXP 6480464 CYP2E1 results in increased chemical synthesis of N-acetyl-4-benzoquinoneimine CTD PMID:20566340 N-acetyl-L-cysteine multiple interactions ISO RGD:2475 6480464 [Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP2E1 protein] more ... CTD PMID:21424224 more ... N-acetyl-L-cysteine multiple interactions ISO RGD:10451 6480464 Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA], Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein] CTD PMID:30423402 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:10451 6480464 [AQP4 protein affects the susceptibility to 1-Methyl-4-phenylpyridinium] which affects the expression of CYP2E1 mRNA CTD PMID:20615459 N-methylformamide increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of methylformamide CTD PMID:1538706 N-methylformamide increases metabolic processing ISO RGD:2475 6480464 CYP2E1 protein results in increased metabolism of methylformamide CTD PMID:1538706 N-methylformamide multiple interactions ISO RGD:2475 6480464 4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide] more ... CTD PMID:1538706 N-Nitrosodi-n-butylamine multiple interactions EXP 6480464 [CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to dibutylnitrosamine, [CYP2E1 protein co-treated with POR protein] results in increased susceptibility to dibutylnitrosamine CTD PMID:11035158 , PMID:11733072 N-Nitrosodi-n-propylamine multiple interactions EXP 6480464 [CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to N-nitroso(di-n-propyl)amine more ... CTD PMID:11035158 more ... N-Nitrosodi-n-propylamine increases activity EXP 6480464 CYP2E1 protein results in increased activity of N-nitroso(di-n-propyl)amine CTD PMID:15728263 N-Nitrosodi-n-propylamine affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of N-nitroso(di-n-propyl)amine CTD PMID:10910959 N-Nitrosodiethanolamine increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of N-nitrosodiethanolamine CTD PMID:18616954 N-nitrosodiethylamine multiple interactions EXP 6480464 [CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to Diethylnitrosamine more ... CTD PMID:11035158 more ... N-nitrosodiethylamine increases expression ISO RGD:2475 6480464 Diethylnitrosamine results in increased expression of CYP2E1 mRNA, Diethylnitrosamine results in increased expression of CYP2E1 protein CTD PMID:30423403 N-nitrosodiethylamine decreases expression ISO RGD:2475 6480464 Diethylnitrosamine results in decreased expression of CYP2E1 mRNA CTD PMID:19638242 more ... N-nitrosodiethylamine increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to Diethylnitrosamine CTD PMID:18056438 N-nitrosodiethylamine multiple interactions ISO RGD:2475 6480464 [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of CYP2E1 mRNA more ... CTD PMID:14656948 more ... N-nitrosodiethylamine increases response to substance EXP 6480464 CYP2E1 protein results in increased susceptibility to Diethylnitrosamine CTD PMID:14669323 N-nitrosodiethylamine multiple interactions ISO RGD:10451 6480464 CYP2E1 protein promotes the reaction [Diethylnitrosamine results in increased expression of BAX mRNA], CYP2E1 protein promotes the reaction [Diethylnitrosamine results in increased expression of CASP3 mRNA] CTD PMID:18056438 N-nitrosodiethylamine increases activity EXP 6480464 CYP2E1 protein results in increased activity of Diethylnitrosamine CTD PMID:15728263 N-nitrosodiethylamine affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of Diethylnitrosamine CTD PMID:2655891 N-nitrosodimethylamine multiple interactions EXP 6480464 [[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to Dimethylnitrosamine] which results in increased mutagenesis of HPRT1 gene more ... CTD PMID:11181492 more ... N-nitrosodimethylamine decreases activity EXP 6480464 Dimethylnitrosamine results in decreased activity of CYP2E1 protein CTD PMID:24561005 N-nitrosodimethylamine affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of Dimethylnitrosamine CTD PMID:16235733 , PMID:2655891 N-nitrosodimethylamine decreases methylation ISO RGD:2475 6480464 CYP2E1 protein results in decreased methylation of Dimethylnitrosamine CTD PMID:3113478 , PMID:8194125 N-nitrosodimethylamine decreases expression ISO RGD:10451 6480464 Dimethylnitrosamine results in decreased expression of CYP2E1 mRNA CTD PMID:11356909 N-nitrosodimethylamine increases metabolic processing ISO RGD:2475 6480464 CYP2E1 protein results in increased metabolism of Dimethylnitrosamine CTD PMID:15763544 N-nitrosodimethylamine multiple interactions ISO RGD:2475 6480464 allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine], S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine] CTD PMID:15763544 , PMID:8117321 N-nitrosodimethylamine increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Dimethylnitrosamine CTD PMID:12464242 , PMID:15242818 N-nitrosodimethylamine decreases methylation EXP 6480464 CYP2E1 protein results in decreased methylation of Dimethylnitrosamine CTD PMID:11181492 N-Nitrosomethylethylamine multiple interactions EXP 6480464 CYP2E1 protein affects the metabolism of and results in increased activity of methylethylnitrosamine CTD PMID:11600130 N-nitrosomorpholine multiple interactions EXP 6480464 CYP2E1 protein affects the metabolism of and results in increased activity of N-nitrosomorpholine CTD PMID:11774366 N-nitrosopiperidine multiple interactions EXP 6480464 CYP2E1 protein affects the metabolism of and results in increased activity of N-nitrosopiperidine CTD PMID:11774366 N-Nitrosopyrrolidine multiple interactions EXP 6480464 CYP2E1 protein affects the metabolism of and results in increased activity of N-Nitrosopyrrolidine CTD PMID:11774366 NADP zwitterion multiple interactions EXP 6480464 [vinyl carbamate co-treated with NADP] inhibits the reaction [CYP2E1 protein results in decreased methylation of Dimethylnitrosamine] CTD PMID:11181492 NADP zwitterion multiple interactions ISO RGD:2475 6480464 [2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP2E1 protein CTD PMID:24713513 NADP(+) multiple interactions EXP 6480464 [vinyl carbamate co-treated with NADP] inhibits the reaction [CYP2E1 protein results in decreased methylation of Dimethylnitrosamine] CTD PMID:11181492 NADP(+) multiple interactions ISO RGD:2475 6480464 [2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP2E1 protein CTD PMID:24713513 naphthalene increases expression EXP 6480464 naphthalene results in increased expression of CYP2E1 mRNA CTD PMID:20500019 nefazodone increases expression ISO RGD:2475 6480464 nefazodone results in increased expression of CYP2E1 mRNA CTD PMID:24136188 neomycin multiple interactions ISO RGD:2475 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2E1 mRNA CTD PMID:30545405 nicotinamide multiple interactions ISO RGD:2475 6480464 [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein], [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA] CTD PMID:27919644 nicotine increases expression ISO RGD:2475 6480464 Nicotine results in increased expression of CYP2E1 protein CTD PMID:16434548 nifedipine decreases activity ISO RGD:10451 6480464 Nifedipine results in decreased activity of CYP2E1 protein CTD PMID:18420780 nitric oxide multiple interactions EXP 6480464 [CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Nitric Oxide CTD PMID:18845238 nitroglycerin increases expression ISO RGD:2475 6480464 Nitroglycerin results in increased expression of CYP2E1 mRNA CTD PMID:12102619 o-anisidine increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of 2-anisidine CTD PMID:15828049 o-xylene increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of 2-xylene CTD PMID:8558417 o-xylene increases expression ISO RGD:2475 6480464 2-xylene results in increased expression of CYP2E1 protein CTD PMID:8517779 , PMID:8996725 o-xylene multiple interactions ISO RGD:2475 6480464 Acetone promotes the reaction [2-xylene results in increased expression of CYP2E1 protein] CTD PMID:8996725 o-xylene multiple interactions EXP 6480464 Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 2-xylene] CTD PMID:8558417 o-xylene increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of 2-xylene CTD PMID:17156750 obeticholic acid decreases expression EXP 6480464 obeticholic acid results in decreased expression of CYP2E1 mRNA CTD PMID:27939613 ochratoxin A increases response to substance EXP 6480464 CYP2E1 protein results in increased susceptibility to ochratoxin A CTD PMID:11189750 octadecanoic acid increases activity EXP 6480464 stearic acid results in increased activity of CYP2E1 protein CTD PMID:26739624 okadaic acid decreases expression ISO RGD:10451 6480464 Okadaic Acid results in decreased expression of CYP2E1 mRNA CTD PMID:25270620 oleanolic acid multiple interactions ISO RGD:2475 6480464 Oleanolic Acid inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein] CTD PMID:25111957 oleanolic acid decreases expression ISO RGD:2475 6480464 Oleanolic Acid results in decreased expression of CYP2E1 mRNA CTD PMID:18706400 oleanolic acid decreases expression ISO RGD:10451 6480464 Oleanolic Acid results in decreased expression of CYP2E1 mRNA CTD PMID:18706400 oleanolic acid multiple interactions ISO RGD:10451 6480464 Oleanolic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein] CTD PMID:10355542 oleic acid multiple interactions ISO RGD:2475 6480464 [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA] more ... CTD PMID:26854922 oleic acid multiple interactions EXP 6480464 [6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:30611723 oleic acid increases expression EXP 6480464 Oleic Acid results in increased expression of CYP2E1 mRNA CTD PMID:30611723 oltipraz affects activity EXP 6480464 oltipraz affects the activity of CYP2E1 protein CTD PMID:10775323 omeprazole multiple interactions EXP 6480464 Omeprazole results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:15802389 orphenadrine multiple interactions EXP 6480464 Orphenadrine inhibits the reaction [CYP2E1 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin], Orphenadrine inhibits the reaction [CYP2E1 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin] CTD PMID:9241656 orphenadrine decreases activity EXP 6480464 Orphenadrine results in decreased activity of CYP2E1 protein CTD PMID:9241656 oxirane multiple interactions ISO RGD:10451 6480464 [CYP2E1 protein results in increased metabolism of ethylene] which results in increased abundance of Ethylene Oxide CTD PMID:21785163 oxycodone increases expression ISO RGD:2475 6480464 Oxycodone results in increased expression of CYP2E1 mRNA CTD PMID:23439660 ozone decreases expression ISO RGD:10451 6480464 Ozone results in decreased expression of CYP2E1 mRNA CTD PMID:12763052 p-cresol increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of 4-cresol CTD PMID:16174805 p-xylene increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of 4-xylene CTD PMID:8558417 p-xylene multiple interactions EXP 6480464 Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-xylene] CTD PMID:8558417 p-xylene increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of 4-xylene CTD PMID:17156750 paclitaxel decreases activity ISO RGD:2475 6480464 Paclitaxel results in decreased activity of CYP2E1 protein CTD PMID:24882083 paclitaxel multiple interactions ISO RGD:2475 6480464 turmeric extract affects the reaction [Paclitaxel results in decreased activity of CYP2E1 protein] CTD PMID:24882083 paracetamol multiple interactions ISO RGD:10451 6480464 [Acetaminophen results in increased activity of CYP2E1 protein] inhibits the reaction [PPARA protein results in increased oxidation of Fatty Acids] more ... CTD PMID:11376689 more ... paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of CYP2E1 mRNA, Acetaminophen results in decreased expression of CYP2E1 protein CTD PMID:29067470 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of CYP2E1 mRNA, Acetaminophen results in increased expression of CYP2E1 protein CTD PMID:23728527 more ... paracetamol increases activity ISO RGD:10451 6480464 Acetaminophen results in increased activity of CYP2E1 protein CTD PMID:19256530 more ... paracetamol increases activity ISO RGD:2475 6480464 Acetaminophen results in increased activity of CYP2E1 protein CTD PMID:19932728 paracetamol decreases expression ISO RGD:10451 6480464 Acetaminophen results in decreased expression of CYP2E1 mRNA, Acetaminophen results in decreased expression of CYP2E1 protein CTD PMID:15576447 more ... paracetamol decreases activity ISO RGD:10451 6480464 Acetaminophen results in decreased activity of CYP2E1 protein CTD PMID:26772156 paracetamol decreases expression ISO RGD:2475 6480464 Acetaminophen results in decreased expression of CYP2E1 mRNA CTD PMID:17126469 , PMID:21807079 paracetamol increases response to substance ISO RGD:2475 6480464 CYP2E1 protein results in increased susceptibility to Acetaminophen CTD PMID:21130154 paracetamol increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to Acetaminophen CTD PMID:11323178 more ... paracetamol increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of Acetaminophen CTD PMID:19002106 paracetamol increases expression ISO RGD:10451 6480464 Acetaminophen results in increased expression of CYP2E1 mRNA, Acetaminophen results in increased expression of CYP2E1 protein CTD PMID:12958197 more ... paracetamol affects expression ISO RGD:10451 6480464 Acetaminophen affects the expression of CYP2E1 mRNA CTD PMID:17562736 paracetamol multiple interactions EXP 6480464 [CYP2E1 protein co-treated with CYP1A2 protein] results in increased susceptibility to Acetaminophen more ... CTD PMID:11212141 more ... paracetamol increases response to substance EXP 6480464 CYP2E1 protein results in increased susceptibility to Acetaminophen CTD PMID:11212141 , PMID:28762043 paracetamol increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Acetaminophen CTD PMID:12464242 , PMID:15576447 paracetamol affects metabolic processing ISO RGD:2475 6480464 CYP2E1 protein affects the metabolism of Acetaminophen CTD PMID:15772367 paracetamol increases expression ISO RGD:2475 6480464 Acetaminophen results in increased expression of CYP2E1 protein CTD PMID:18798224 paracetamol multiple interactions ISO RGD:2475 6480464 [Acetaminophen co-treated with Uranium analog] results in decreased expression of CYP2E1 mRNA more ... CTD PMID:11562448 more ... paracetamol affects response to substance ISO RGD:10451 6480464 CYP2E1 protein affects the susceptibility to Acetaminophen CTD PMID:19256530 paraquat multiple interactions ISO RGD:10451 6480464 [Maneb co-treated with Paraquat] results in increased expression of CYP2E1 mRNA more ... CTD PMID:16510128 , PMID:20964710 paraquat increases expression ISO RGD:2475 6480464 Paraquat results in increased expression of CYP2E1 mRNA, Paraquat results in increased expression of CYP2E1 protein CTD PMID:20553223 more ... paraquat multiple interactions ISO RGD:2475 6480464 [Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein more ... CTD PMID:20553223 , PMID:23159886 paraquat increases activity ISO RGD:2475 6480464 Paraquat results in increased activity of CYP2E1 protein CTD PMID:20888808 parathion affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of Parathion CTD PMID:12669189 pentachlorobenzene increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of pentachlorobenzene CTD PMID:7747284 pentachlorobenzene increases expression ISO RGD:2475 6480464 pentachlorobenzene results in increased expression of CYP2E1 protein CTD PMID:10696772 pentachlorobenzene increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of pentachlorobenzene CTD PMID:7747284 pentachlorophenol increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of Pentachlorophenol CTD PMID:7747284 pentachlorophenol multiple interactions EXP 6480464 Pentachlorophenol inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-hydroxymethylpyrene] which results in increased mutagenesis of HPRT1 gene], Pentachlorophenol inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene] CTD PMID:25243916 perfluorooctane-1-sulfonic acid affects expression ISO RGD:10451 6480464 perfluorooctane sulfonic acid affects the expression of CYP2E1 mRNA CTD PMID:19429403 perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 perfluorooctane sulfonic acid inhibits the reaction [CYP2E1 protein results in increased oxidation of Chlorzoxazone] CTD PMID:21964418 perfluorooctanoic acid decreases expression ISO RGD:10451 6480464 perfluorooctanoic acid results in decreased expression of CYP2E1 mRNA CTD PMID:17681415 perfluorooctanoic acid multiple interactions ISO RGD:10451 6480464 Dietary Fats, Unsaturated inhibits the reaction [perfluorooctanoic acid results in increased expression of CYP2E1 mRNA] CTD PMID:23626681 perfluorooctanoic acid affects expression ISO RGD:10451 6480464 perfluorooctanoic acid affects the expression of CYP2E1 mRNA CTD PMID:19429403 phenacetin affects metabolic processing ISO RGD:2475 6480464 CYP2E1 protein affects the metabolism of Phenacetin CTD PMID:15879494 phenanthrene multiple interactions EXP 6480464 CYP2E1 protein results in increased metabolism of and results in increased activity of phenanthrene CTD PMID:19766613 phenanthrene multiple interactions ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of and results in increased activity of phenanthrene CTD PMID:19766613 phenethyl caffeate multiple interactions ISO RGD:2475 6480464 [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP2E1 mRNA CTD PMID:20360939 phenethyl caffeate multiple interactions ISO RGD:10451 6480464 caffeic acid phenethyl ester inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline] CTD PMID:18436364 phenethyl isothiocyanate multiple interactions ISO RGD:2475 6480464 phenethyl isothiocyanate inhibits the reaction [[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde] more ... CTD PMID:7562599 , PMID:7601153 phenethyl isothiocyanate decreases activity EXP 6480464 phenethyl isothiocyanate results in decreased activity of CYP2E1 protein CTD PMID:10616189 , PMID:17582584 phenethyl isothiocyanate decreases expression ISO RGD:2475 6480464 phenethyl isothiocyanate results in decreased expression of CYP2E1 protein CTD PMID:7601153 phenformin increases expression ISO RGD:2475 6480464 Phenformin results in increased expression of CYP2E1 mRNA CTD PMID:31324951 phenobarbital multiple interactions ISO RGD:2475 6480464 [Phenobarbital co-treated with beta-Naphthoflavone] results in decreased expression of CYP2E1 protein, Choline deficiency promotes the reaction [Phenobarbital results in increased expression of CYP2E1 protein] CTD PMID:18798224 , PMID:30842367 phenobarbital decreases expression ISO RGD:10451 6480464 Phenobarbital results in decreased expression of CYP2E1 mRNA CTD PMID:30503582 phenobarbital increases expression ISO RGD:2475 6480464 Phenobarbital results in increased expression of CYP2E1 mRNA, Phenobarbital results in increased expression of CYP2E1 protein CTD PMID:18798224 , PMID:23273579 phenobarbital increases activity ISO RGD:2475 6480464 Phenobarbital results in increased activity of CYP2E1 protein CTD PMID:15490126 phenobarbital decreases expression ISO RGD:2475 6480464 Phenobarbital results in decreased expression of CYP2E1 mRNA, Phenobarbital results in decreased expression of CYP2E1 protein CTD PMID:15596064 more ... phenol increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of Phenol CTD PMID:11701230 phenol increases metabolic processing ISO RGD:2475 6480464 CYP2E1 protein results in increased metabolism of Phenol CTD PMID:8211999 phenol multiple interactions ISO RGD:2475 6480464 [CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of Phenol more ... CTD PMID:8211999 phenol multiple interactions EXP 6480464 [CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of Phenol CTD PMID:15051535 phenthoate decreases activity EXP 6480464 phenthoate results in decreased activity of CYP2E1 protein CTD PMID:22634058 phenthoate multiple interactions EXP 6480464 phenthoate inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:22634058 phenylglyoxylic acid multiple interactions EXP 6480464 CYP2E1 polymorphism affects the metabolism of [mandelic acid co-treated with phenylglyoxylic acid] CTD PMID:25562543 phenytoin multiple interactions EXP 6480464 NOC 18 inhibits the reaction [Phenytoin results in increased expression of CYP2E1 mRNA] CTD PMID:18206661 phenytoin decreases expression ISO RGD:2475 6480464 Phenytoin results in decreased expression of CYP2E1 mRNA CTD PMID:17381134 phenytoin increases expression EXP 6480464 Phenytoin results in increased expression of CYP2E1 mRNA, Phenytoin results in increased expression of CYP2E1 protein CTD PMID:18206661 PhIP increases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of CYP2E1 mRNA CTD PMID:29362861 PhIP multiple interactions EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:29362861 phorbol 13-acetate 12-myristate multiple interactions EXP 6480464 Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]] more ... CTD PMID:8531136 more ... phorbol 13-acetate 12-myristate increases expression EXP 6480464 Tetradecanoylphorbol Acetate results in increased expression of CYP2E1 protein CTD PMID:8798623 phthalaldehyde decreases expression ISO RGD:10451 6480464 o-Phthalaldehyde results in decreased expression of CYP2E1 mRNA CTD PMID:20112102 pioglitazone multiple interactions ISO RGD:10451 6480464 [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CYP2E1 mRNA CTD PMID:27935865 piperidin-2-one increases abundance ISO RGD:10451 6480464 CYP2E1 protein results in increased abundance of 2-piperidone CTD PMID:23811823 potassium dichromate increases expression ISO RGD:10451 6480464 Potassium Dichromate results in increased expression of CYP2E1 mRNA CTD PMID:23608068 primaquine increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Primaquine CTD PMID:19616568 primaquine multiple interactions EXP 6480464 [CYP2E1 protein results in increased expression of HBG2 protein] which affects the susceptibility to Primaquine CTD PMID:19616568 prochloraz decreases expression EXP 6480464 prochloraz results in decreased expression of CYP2E1 mRNA CTD PMID:20035023 procymidone multiple interactions ISO RGD:10451 6480464 procymidone results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:12787915 procymidone increases expression ISO RGD:10451 6480464 procymidone results in increased expression of CYP2E1 mRNA CTD PMID:12787915 profenofos decreases activity EXP 6480464 profenofos results in decreased activity of CYP2E1 protein CTD PMID:22634058 profenofos multiple interactions EXP 6480464 profenofos inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:22634058 progesterone affects expression ISO RGD:10451 6480464 Progesterone affects the expression of CYP2E1 mRNA CTD PMID:17251523 progesterone multiple interactions ISO RGD:2475 6480464 Progesterone promotes the reaction [Benzene results in decreased activity of CYP2E1 protein] CTD PMID:18407866 prop-2-yn-1-ol increases metabolic processing ISO RGD:2475 6480464 CYP2E1 protein results in increased metabolism of propargyl alcohol CTD PMID:11306107 propacetamol increases expression ISO RGD:10451 6480464 propacetamol results in increased expression of CYP2E1 protein CTD PMID:29574133 propacetamol multiple interactions ISO RGD:10451 6480464 kaempferol inhibits the reaction [propacetamol results in increased expression of CYP2E1 protein] CTD PMID:29574133 propan-2-ol multiple interactions ISO RGD:2475 6480464 2-Propanol binds to and results in increased expression of CYP2E1 protein, 2-Propanol inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] CTD PMID:3337723 , PMID:7710944 propan-2-ol increases expression ISO RGD:2475 6480464 2-Propanol results in increased expression of CYP2E1 protein CTD PMID:9118891 propetamphos multiple interactions ISO RGD:2475 6480464 [cypermethrin co-treated with propetamphos] results in increased activity of CYP2E1 protein CTD PMID:25926273 propetamphos increases activity ISO RGD:2475 6480464 propetamphos results in increased activity of CYP2E1 protein CTD PMID:25926273 propiconazole decreases expression ISO RGD:2475 6480464 propiconazole results in decreased expression of CYP2E1 protein CTD PMID:7986207 propylparaben decreases activity ISO RGD:2475 6480464 propylparaben results in decreased activity of CYP2E1 protein CTD PMID:27432241 psoralen decreases expression ISO RGD:10451 6480464 Ficusin results in decreased expression of CYP2E1 protein CTD PMID:22173200 puerarin multiple interactions ISO RGD:10451 6480464 puerarin inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline] CTD PMID:18038910 puerarin increases expression ISO RGD:10451 6480464 puerarin results in increased expression of CYP2E1 protein CTD PMID:18038910 purpurin decreases activity EXP 6480464 purpurin results in decreased activity of CYP2E1 protein CTD PMID:12379470 purpurogallin multiple interactions ISO RGD:2475 6480464 purpurogallin inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] CTD PMID:7710944 pyrazinecarboxamide multiple interactions ISO RGD:2475 6480464 [Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein more ... CTD PMID:27919644 pyrazines increases expression ISO RGD:2475 6480464 Pyrazines results in increased expression of CYP2E1 protein CTD PMID:8117321 pyrazines increases activity ISO RGD:2475 6480464 Pyrazines results in increased activity of CYP2E1 protein CTD PMID:8117321 pyrazines multiple interactions ISO RGD:2475 6480464 allyl sulfide inhibits the reaction [Pyrazines results in increased activity of CYP2E1 protein], allyl sulfide inhibits the reaction [Pyrazines results in increased expression of CYP2E1 protein] CTD PMID:8117321 pyrene decreases expression ISO RGD:2475 6480464 pyrene results in decreased expression of CYP2E1 mRNA CTD PMID:30240548 pyridine multiple interactions EXP 6480464 CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA], Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA]] CTD PMID:12147272 pyridine increases activity ISO RGD:2475 6480464 pyridine results in increased activity of CYP2E1 protein CTD PMID:11181506 more ... pyridine increases expression ISO RGD:2475 6480464 pyridine results in increased expression of CYP2E1 mRNA, pyridine results in increased expression of CYP2E1 protein CTD PMID:10215695 more ... pyridine multiple interactions ISO RGD:2475 6480464 [pyridine co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 mRNA more ... CTD PMID:10215695 more ... pyridine increases expression EXP 6480464 pyridine results in increased expression of CYP2E1 protein CTD PMID:8074729 pyridine decreases activity EXP 6480464 pyridine results in decreased activity of CYP2E1 protein CTD PMID:12464242 pyridine N-oxide increases expression ISO RGD:2475 6480464 pyridine N-oxide results in increased expression of CYP2E1 protein CTD PMID:1379807 pyridines multiple interactions ISO RGD:2475 6480464 Pyridines inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:21600194 pyrogallol increases activity ISO RGD:10451 6480464 Pyrogallol results in increased activity of CYP2E1 protein CTD PMID:18789925 pyrogallol multiple interactions ISO RGD:10451 6480464 resveratrol inhibits the reaction [Pyrogallol results in increased activity of CYP2E1 protein], resveratrol inhibits the reaction [Pyrogallol results in increased expression of CYP2E1 mRNA] CTD PMID:18789925 pyrogallol increases expression ISO RGD:10451 6480464 Pyrogallol results in increased expression of CYP2E1 mRNA CTD PMID:18789925 quartz decreases expression ISO RGD:2475 6480464 Quartz results in decreased expression of CYP2E1 mRNA CTD PMID:19836432 quercetin multiple interactions ISO RGD:10451 6480464 Quercetin inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 protein] CTD PMID:26218279 quercetin decreases activity EXP 6480464 Quercetin results in decreased activity of CYP2E1 protein CTD PMID:28232125 , PMID:29753067 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [[CYP2E1 protein results in increased susceptibility to Docosahexaenoic Acids] which results in increased phosphorylation of MAP2K4 protein] more ... CTD PMID:16963249 , PMID:19325051 quercetin decreases activity ISO RGD:10451 6480464 Quercetin results in decreased activity of CYP2E1 protein CTD PMID:18420780 quercetin multiple interactions ISO RGD:2475 6480464 Quercetin inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] more ... CTD PMID:11306697 more ... quercetin 3-O-beta-D-galactopyranoside decreases activity ISO RGD:10451 6480464 hyperoside results in decreased activity of CYP2E1 protein CTD PMID:26772156 quercetin 3-O-beta-D-galactopyranoside multiple interactions ISO RGD:10451 6480464 hyperoside inhibits the reaction [Acetaminophen results in decreased activity of CYP2E1 protein] CTD PMID:26772156 quinacrine multiple interactions ISO RGD:2475 6480464 Quinacrine binds to and results in decreased activity of CYP2E1 protein CTD PMID:18754103 quinacrine decreases expression ISO RGD:2475 6480464 Quinacrine results in decreased expression of CYP2E1 protein CTD PMID:18754103 quinidine decreases activity ISO RGD:10451 6480464 Quinidine results in decreased activity of CYP2E1 protein CTD PMID:18420780 quinoline increases hydroxylation EXP 6480464 CYP2E1 protein results in increased hydroxylation of quinoline CTD PMID:8824525 quinoline increases hydroxylation ISO RGD:2475 6480464 CYP2E1 protein results in increased hydroxylation of quinoline CTD PMID:8824525 quinolines multiple interactions ISO RGD:2475 6480464 Quinolines inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] CTD PMID:21600194 rac-1,2-dichloropropane increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of propylene dichloride CTD PMID:1664256 reactive oxygen species multiple interactions EXP 6480464 [CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Reactive Oxygen Species more ... CTD PMID:18845238 , PMID:22222162 reactive oxygen species increases chemical synthesis EXP 6480464 CYP2E1 protein results in increased chemical synthesis of Reactive Oxygen Species CTD PMID:10498651 reactive oxygen species multiple interactions ISO RGD:10451 6480464 [CYP2E1 protein results in increased hydroxylation of 4-biphenylamine] which results in increased abundance of Reactive Oxygen Species CTD PMID:25601990 reactive oxygen species decreases response to substance ISO RGD:2475 6480464 CYP2E1 protein results in decreased susceptibility to Reactive Oxygen Species CTD PMID:12470497 reactive oxygen species affects chemical synthesis ISO RGD:2475 6480464 CYP2E1 protein affects the chemical synthesis of Reactive Oxygen Species CTD PMID:14693714 resveratrol increases expression ISO RGD:10451 6480464 resveratrol results in increased expression of CYP2E1 mRNA CTD PMID:22610192 resveratrol multiple interactions ISO RGD:10451 6480464 resveratrol inhibits the reaction [CYP2E1 protein results in increased metabolism of Chlorzoxazone] more ... CTD PMID:18789925 , PMID:25956474 resveratrol affects expression ISO RGD:2475 6480464 resveratrol affects the expression of CYP2E1 mRNA CTD PMID:15748624 resveratrol decreases activity ISO RGD:10451 6480464 resveratrol analog results in decreased activity of CYP2E1 protein, resveratrol results in decreased activity of CYP2E1 protein CTD PMID:16684708 more ... retinyl acetate multiple interactions ISO RGD:10451 6480464 [LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of CYP2E1 mRNA CTD PMID:28123100 Retrorsine increases expression ISO RGD:2475 6480464 retrorsine results in increased expression of CYP2E1 CTD PMID:24799337 riddelliine increases expression ISO RGD:2475 6480464 riddelliine results in increased expression of CYP2E1 mRNA CTD PMID:18047722 , PMID:18047727 rifampicin increases activity EXP 6480464 Rifampin results in increased activity of CYP2E1 protein CTD PMID:18071298 rifampicin decreases expression ISO RGD:10451 6480464 Rifampin results in decreased expression of CYP2E1 mRNA CTD PMID:30503582 rifampicin multiple interactions ISO RGD:10451 6480464 [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP2E1 protein CTD PMID:25835148 rifampicin decreases expression EXP 6480464 Rifampin results in decreased expression of CYP2E1 mRNA CTD PMID:22258563 rifampicin increases expression EXP 6480464 Rifampin results in increased expression of CYP2E1 mRNA, Rifampin results in increased expression of CYP2E1 protein CTD PMID:18071298 , PMID:22733800 rifampicin multiple interactions EXP 6480464 [Rifampin co-treated with Monocrotophos] results in increased activity of CYP2E1 protein more ... CTD PMID:22733800 rifampicin multiple interactions ISO RGD:2475 6480464 [Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein more ... CTD PMID:15132840 , PMID:27919644 rotenone increases expression ISO RGD:2475 6480464 Rotenone results in increased expression of CYP2E1 mRNA CTD PMID:28374803 S-adenosyl-L-methioninate multiple interactions ISO RGD:10451 6480464 S-Adenosylmethionine inhibits the reaction [Acetaminophen results in decreased expression of CYP2E1 protein], S-Adenosylmethionine promotes the reaction [Carbon Tetrachloride results in decreased expression of and results in decreased activity of CYP2E1 protein] CTD PMID:15983038 , PMID:22683606 S-adenosyl-L-methioninate decreases activity ISO RGD:2475 6480464 S-Adenosylmethionine results in decreased activity of CYP2E1 protein CTD PMID:15763544 S-adenosyl-L-methioninate multiple interactions ISO RGD:2475 6480464 S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol] more ... CTD PMID:15763544 S-adenosyl-L-methioninate decreases activity EXP 6480464 S-Adenosylmethionine results in decreased activity of CYP2E1 protein CTD PMID:15763544 S-adenosyl-L-methionine decreases activity ISO RGD:2475 6480464 S-Adenosylmethionine results in decreased activity of CYP2E1 protein CTD PMID:15763544 S-adenosyl-L-methionine multiple interactions ISO RGD:2475 6480464 S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol] more ... CTD PMID:15763544 S-adenosyl-L-methionine multiple interactions ISO RGD:10451 6480464 S-Adenosylmethionine inhibits the reaction [Acetaminophen results in decreased expression of CYP2E1 protein], S-Adenosylmethionine promotes the reaction [Carbon Tetrachloride results in decreased expression of and results in decreased activity of CYP2E1 protein] CTD PMID:15983038 , PMID:22683606 S-adenosyl-L-methionine decreases activity EXP 6480464 S-Adenosylmethionine results in decreased activity of CYP2E1 protein CTD PMID:15763544 S-butyl-DL-homocysteine (S,R)-sulfoximine increases response to substance EXP 6480464 CYP2E1 protein results in increased susceptibility to Buthionine Sulfoximine, CYP2E1 results in increased susceptibility to Buthionine Sulfoximine CTD PMID:12086689 , PMID:12566070 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions EXP 6480464 Buthionine Sulfoximine promotes the reaction [CYP2E1 protein results in increased expression of COL1A2 mRNA] more ... CTD PMID:10498651 more ... safrole decreases activity EXP 6480464 Safrole results in decreased activity of CYP2E1 protein CTD PMID:15778010 salvianolic acid B multiple interactions ISO RGD:2475 6480464 salvianolic acid B inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein] CTD PMID:27989594 satraplatin decreases activity EXP 6480464 satraplatin results in decreased activity of CYP2E1 protein CTD PMID:24882083 selenium atom multiple interactions ISO RGD:2475 6480464 [Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP2E1 protein] CTD PMID:21424224 senecionine increases expression EXP 6480464 senecionine results in increased expression of CYP2E1 mRNA CTD PMID:26100227 sevoflurane increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of sevoflurane CTD PMID:7879937 Shikonin decreases activity ISO RGD:2475 6480464 shikonin results in decreased activity of CYP2E1 protein CTD PMID:28941798 Shikonin decreases activity EXP 6480464 shikonin results in decreased activity of CYP2E1 protein CTD PMID:28941798 skatole decreases expression EXP 6480464 Skatole results in decreased expression of CYP2E1 mRNA CTD PMID:28571685 sodium arsenite increases expression ISO RGD:10451 6480464 sodium arsenite results in increased expression of CYP2E1 mRNA, sodium arsenite results in increased expression of CYP2E1 protein CTD PMID:25065748 , PMID:29044176 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of CYP2E1 mRNA CTD PMID:29301061 sodium arsenite decreases response to substance EXP 6480464 CYP2E1 protein results in decreased susceptibility to sodium arsenite CTD PMID:19154403 sodium arsenite decreases expression ISO RGD:10451 6480464 sodium arsenite results in decreased expression of CYP2E1 mRNA CTD PMID:17350061 , PMID:17451858 sodium chromate multiple interactions ISO RGD:2475 6480464 Carbon Monoxide inhibits the reaction [CYP2E1 protein results in increased reduction of sodium chromate(VI)] more ... CTD PMID:1903091 staurosporine multiple interactions ISO RGD:2475 6480464 Staurosporine inhibits the reaction [INS1 protein results in decreased expression of CYP2E1 mRNA] CTD PMID:11306697 staurosporine increases expression ISO RGD:2475 6480464 Staurosporine results in increased expression of CYP2E1 mRNA CTD PMID:11306697 streptozocin decreases expression ISO RGD:10451 6480464 Streptozocin results in decreased expression of CYP2E1 protein CTD PMID:12700423 streptozocin multiple interactions ISO RGD:2475 6480464 [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:24815820 streptozocin increases expression ISO RGD:2475 6480464 Streptozocin results in increased expression of CYP2E1 mRNA, Streptozocin results in increased expression of CYP2E1 protein CTD PMID:11752103 more ... styrene decreases metabolic processing EXP 6480464 CYP2E1 gene polymorphism results in decreased metabolism of Styrene CTD PMID:16125881 styrene increases oxidation ISO RGD:2475 6480464 CYP2E1 protein results in increased oxidation of Styrene CTD PMID:26463279 styrene increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of Styrene CTD PMID:24320693 styrene increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of Styrene CTD PMID:1664256 styrene increases expression EXP 6480464 Styrene results in increased expression of CYP2E1 mRNA CTD PMID:21030303 styrene affects response to substance EXP 6480464 CYP2E1 gene polymorphism affects the susceptibility to Styrene CTD PMID:12604177 more ... styrene increases expression ISO RGD:2475 6480464 Styrene results in increased expression of CYP2E1 mRNA, Styrene results in increased expression of CYP2E1 protein CTD PMID:16418063 , PMID:18202523 styrene multiple interactions ISO RGD:2475 6480464 gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2E1 mRNA], gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2E1 protein] CTD PMID:18202523 styrene multiple interactions ISO RGD:10451 6480464 [Disulfiram results in decreased activity of CYP2E1 protein] which affects the activity of Styrene, [Ditiocarb co-treated with CYP2E1 gene mutant form] results in decreased metabolism of Styrene CTD PMID:12746132 , PMID:20470765 styrene increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to Styrene CTD PMID:15110085 styrene affects metabolic processing ISO RGD:10451 6480464 CYP2E1 protein affects the metabolism of Styrene CTD PMID:12746132 styrene multiple interactions EXP 6480464 [Disulfiram results in decreased activity of CYP2E1 protein] which affects the activity of Styrene more ... CTD PMID:12464798 more ... styrene affects oxidation EXP 6480464 CYP2E1 protein affects the oxidation of Styrene CTD PMID:16872732 styrene increases response to substance EXP 6480464 CYP2E1 gene polymorphism results in increased susceptibility to Styrene, CYP2E1 protein results in increased susceptibility to Styrene CTD PMID:11535253 , PMID:16872732 styrene affects metabolic processing EXP 6480464 CYP2E1 gene polymorphism affects the metabolism of Styrene, CYP2E1 protein affects the metabolism of Styrene CTD PMID:12464798 more ... styrene oxide increases chemical synthesis EXP 6480464 CYP2E1 results in increased chemical synthesis of styrene oxide, CYP2E1 results in increased chemical synthesis of styrene oxide analog CTD PMID:22366341 Sudan I increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of 1-phenylazo-2-naphthol CTD PMID:17159775 sulforaphane multiple interactions ISO RGD:10451 6480464 sulforafan inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA], sulforafan inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 protein] CTD PMID:21684301 sulforaphane increases expression ISO RGD:10451 6480464 sulforafan results in increased expression of CYP2E1 mRNA CTD PMID:30529165 sunitinib increases expression ISO RGD:2475 6480464 sunitinib results in increased expression of CYP2E1 mRNA CTD PMID:26797788 tamoxifen decreases activity ISO RGD:10451 6480464 Tamoxifen results in decreased activity of CYP2E1 protein CTD PMID:18420780 tamoxifen multiple interactions ISO RGD:10451 6480464 Carbon Tetrachloride promotes the reaction [Tamoxifen results in decreased expression of CYP2E1 mRNA] more ... CTD PMID:29974145 tamoxifen decreases expression ISO RGD:10451 6480464 Tamoxifen results in decreased expression of CYP2E1 mRNA, Tamoxifen results in decreased expression of CYP2E1 protein CTD PMID:29974145 taurine multiple interactions ISO RGD:10451 6480464 Taurine inhibits the reaction [Acetaminophen results in increased activity of CYP2E1 protein], Taurine inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein] CTD PMID:20067817 , PMID:20166895 tebuconazole decreases expression EXP 6480464 tebuconazole results in decreased expression of CYP2E1 mRNA CTD PMID:30458266 tebuconazole increases expression ISO RGD:2475 6480464 tebuconazole results in increased expression of CYP2E1 protein CTD PMID:29923317 tenofovir disoproxil fumarate decreases activity EXP 6480464 Tenofovir results in decreased activity of CYP2E1 protein CTD PMID:17162464 tert-butyl ethyl ether increases expression ISO RGD:2475 6480464 ethyl tert-butyl ether results in increased expression of CYP2E1 mRNA, ethyl tert-butyl ether results in increased expression of CYP2E1 protein CTD PMID:24090815 testosterone increases expression ISO RGD:10451 6480464 Testosterone results in increased expression of CYP2E1 mRNA, Testosterone results in increased expression of CYP2E1 protein CTD PMID:20403060 , PMID:7839370 Tetrachlorobisphenol A increases expression EXP 6480464 tetrachlorodian results in increased expression of CYP2E1 mRNA CTD PMID:31326446 tetrachloroethene increases response to substance ISO RGD:2475 6480464 CYP2E1 protein results in increased susceptibility to Tetrachloroethylene CTD PMID:17433522 tetrachloroethene decreases response to substance ISO RGD:10451 6480464 CYP2E1 gene mutant form results in decreased susceptibility to Tetrachloroethylene CTD PMID:29897530 tetrachloroethene increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of Tetrachloroethylene CTD PMID:29897530 tetrachloroethene multiple interactions EXP 6480464 [CYP2E1 protein results in increased oxidation of Tetrachloroethylene] which results in increased abundance of Trichloroacetic Acid CTD PMID:29897530 tetrachloromethane decreases activity ISO RGD:10451 6480464 Carbon Tetrachloride results in decreased activity of CYP2E1 protein CTD PMID:17038628 more ... tetrachloromethane decreases expression ISO RGD:10451 6480464 Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA, Carbon Tetrachloride results in decreased expression of CYP2E1 protein CTD PMID:12466116 more ... tetrachloromethane increases activity ISO RGD:2475 6480464 Carbon Tetrachloride results in increased activity of CYP2E1 protein CTD PMID:17710613 , PMID:25899501 tetrachloromethane increases activity ISO RGD:10451 6480464 Carbon Tetrachloride results in increased activity of CYP2E1 protein CTD PMID:25445725 tetrachloromethane decreases expression ISO RGD:2475 6480464 Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA, Carbon Tetrachloride results in decreased expression of CYP2E1 protein CTD PMID:14706259 more ... tetrachloromethane increases expression ISO RGD:2475 6480464 Carbon Tetrachloride results in increased expression of CYP2E1 mRNA, Carbon Tetrachloride results in increased expression of CYP2E1 protein CTD PMID:11903743 more ... tetrachloromethane decreases activity ISO RGD:2475 6480464 Carbon Tetrachloride results in decreased activity of CYP2E1 protein CTD PMID:14706259 more ... tetrachloromethane increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Carbon Tetrachloride CTD PMID:15797236 more ... tetrachloromethane increases metabolic processing ISO RGD:2475 6480464 CYP2E1 protein results in increased metabolism of Carbon Tetrachloride CTD PMID:7601153 tetrachloromethane affects metabolic processing ISO RGD:2475 6480464 CYP2E1 protein affects the metabolism of Carbon Tetrachloride CTD PMID:15772367 tetrachloromethane increases degradation ISO RGD:2475 6480464 Carbon Tetrachloride results in increased degradation of CYP2E1 protein CTD PMID:12679053 tetrachloromethane affects expression ISO RGD:2475 6480464 Carbon Tetrachloride affects the expression of CYP2E1 mRNA CTD PMID:17805973 tetrachloromethane multiple interactions ISO RGD:2475 6480464 acteoside inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein] more ... CTD PMID:11903743 more ... tetrachloromethane affects response to substance ISO RGD:10451 6480464 CYP2E1 protein affects the susceptibility to Carbon Tetrachloride CTD PMID:15962327 tetrachloromethane increases activity EXP 6480464 Carbon Tetrachloride results in increased activity of CYP2E1 protein CTD PMID:17710613 tetrachloromethane multiple interactions EXP 6480464 Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] more ... CTD PMID:8531136 , PMID:9143349 tetrachloromethane increases expression ISO RGD:10451 6480464 Carbon Tetrachloride results in increased expression of CYP2E1 mRNA, Carbon Tetrachloride results in increased expression of CYP2E1 protein CTD PMID:17610925 more ... tetrachloromethane multiple interactions ISO RGD:10451 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in decreased expression of CYP2E1 mRNA more ... CTD PMID:10355542 more ... tetrachlorophenol increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of tetrachlorophenol CTD PMID:7747284 tetracycline multiple interactions ISO RGD:10451 6480464 bicyclol inhibits the reaction [Tetracycline results in decreased expression of CYP2E1 mRNA] CTD PMID:19427351 tetracycline decreases expression ISO RGD:10451 6480464 Tetracycline results in decreased expression of CYP2E1 mRNA CTD PMID:19427351 tetrahydrocurcumin multiple interactions ISO RGD:10451 6480464 tetrahydrocurcumin inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA], tetrahydrocurcumin inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein] CTD PMID:30423402 tetraphene increases expression ISO RGD:10451 6480464 benz(a)anthracene results in increased expression of CYP2E1 mRNA CTD PMID:26377693 thallium increases response to substance ISO RGD:2475 6480464 CYP2E1 results in increased susceptibility to Thallium CTD PMID:20549620 theobromine multiple interactions EXP 6480464 4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased metabolism of Theobromine], Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of Theobromine] CTD PMID:10215755 theobromine increases chemical synthesis EXP 6480464 CYP2E1 protein results in increased chemical synthesis of Theobromine CTD PMID:1302044 theobromine increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Theobromine CTD PMID:10215755 theophylline affects metabolic processing ISO RGD:2475 6480464 CYP2E1 protein affects the metabolism of Theophylline CTD PMID:15985363 theophylline increases chemical synthesis EXP 6480464 CYP2E1 protein results in increased chemical synthesis of Theophylline CTD PMID:1302044 theophylline affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of Theophylline CTD PMID:15948934 , PMID:16841220 theophylline affects hydroxylation EXP 6480464 CYP2E1 promoter SNP affects the hydroxylation of Theophylline CTD PMID:16841220 thiamine(1+) chloride multiple interactions ISO RGD:2475 6480464 [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein], [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA] CTD PMID:27919644 thiazoles multiple interactions ISO RGD:2475 6480464 [Thiazoles co-treated with ciprofibrate] results in increased expression of CYP2E1 protein CTD PMID:7587954 thioacetamide multiple interactions ISO RGD:10451 6480464 [CYP2E1 protein results in increased metabolism of Thioacetamide] which results in increased chemical synthesis of thioacetamide-S-oxide more ... CTD PMID:18374380 , PMID:29763686 thioacetamide increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of Thioacetamide CTD PMID:29763686 thioacetamide decreases activity ISO RGD:10451 6480464 Thioacetamide results in decreased activity of CYP2E1 protein CTD PMID:29763686 thioacetamide increases expression ISO RGD:10451 6480464 Thioacetamide results in increased expression of CYP2E1 protein CTD PMID:30625377 thioacetamide decreases expression ISO RGD:10451 6480464 Thioacetamide results in decreased expression of CYP2E1 protein CTD PMID:27349771 thioacetamide increases expression ISO RGD:2475 6480464 Thioacetamide results in increased expression of CYP2E1 protein CTD PMID:20036707 thioacetamide multiple interactions ISO RGD:2475 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP2E1 mRNA, Eugenol inhibits the reaction [Thioacetamide results in increased expression of CYP2E1 protein] CTD PMID:20036707 , PMID:28943392 thioacetamide increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to Thioacetamide CTD PMID:18374380 thioacetamide decreases expression ISO RGD:2475 6480464 Thioacetamide results in decreased expression of CYP2E1 mRNA CTD PMID:16297948 thiophanate-methyl increases expression ISO RGD:2475 6480464 Thiophanate results in increased expression of CYP2E1 protein CTD PMID:10096430 thioridazine decreases activity EXP 6480464 Thioridazine results in decreased activity of CYP2E1 protein CTD PMID:15135088 thiostrepton decreases expression EXP 6480464 Thiostrepton results in decreased expression of CYP2E1 mRNA CTD PMID:22321511 thiram increases metabolic processing ISO RGD:2475 6480464 CYP2E1 protein results in increased metabolism of Thiram CTD PMID:12458634 thiram multiple interactions ISO RGD:2475 6480464 Thiram inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein] CTD PMID:12458634 Tiopronin multiple interactions ISO RGD:2475 6480464 Tiopronin inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein] CTD PMID:19683030 tirapazamine multiple interactions ISO RGD:2475 6480464 1-phenylimidazole inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] more ... CTD PMID:7710944 titanium dioxide increases expression ISO RGD:10451 6480464 titanium dioxide results in increased expression of CYP2E1 mRNA CTD PMID:23557971 titanium dioxide decreases expression ISO RGD:2475 6480464 titanium dioxide results in decreased expression of CYP2E1 mRNA CTD PMID:30012374 toluene affects response to substance EXP 6480464 CYP2E1 gene polymorphism affects the susceptibility to Toluene CTD PMID:17292523 toluene increases expression EXP 6480464 Toluene results in increased expression of CYP2E1 mRNA CTD PMID:16581535 more ... toluene affects methylation EXP 6480464 Toluene affects the methylation of CYP2E1 promoter CTD PMID:25963742 toluene affects activity EXP 6480464 Toluene affects the activity of CYP2E1 protein CTD PMID:25963742 toluene increases activity ISO RGD:2475 6480464 Toluene results in increased activity of CYP2E1 protein CTD PMID:12919724 more ... toluene increases expression ISO RGD:2475 6480464 Toluene results in increased expression of CYP2E1 mRNA, Toluene results in increased expression of CYP2E1 protein CTD PMID:12919724 more ... toluene increases metabolic processing ISO RGD:2475 6480464 CYP2E1 protein results in increased metabolism of Toluene CTD PMID:8461037 toluene affects metabolic processing ISO RGD:2475 6480464 CYP2E1 protein affects the metabolism of Toluene CTD PMID:8620572 toluene increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of Toluene CTD PMID:8461037 toluene multiple interactions ISO RGD:10451 6480464 [Toluene co-treated with Benzene] results in increased activity of CYP2E1 protein CTD PMID:18455711 toluene increases metabolic processing EXP 6480464 CYP2E1 protein alternative form results in increased metabolism of Toluene, CYP2E1 protein results in increased metabolism of Toluene CTD PMID:12464242 more ... toluene increases oxidation ISO RGD:2475 6480464 CYP2E1 protein results in increased oxidation of Toluene CTD PMID:1994898 toluene multiple interactions ISO RGD:2475 6480464 [Benzene results in increased expression of CYP2E1 protein] which results in increased metabolism of Toluene more ... CTD PMID:1994898 more ... toluene multiple interactions EXP 6480464 Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of Toluene], Smoke affects the reaction [Toluene affects the methylation of CYP2E1 promoter] CTD PMID:25963742 , PMID:8558417 trabectedin decreases activity ISO RGD:2475 6480464 trabectedin results in decreased activity of CYP2E1 protein CTD PMID:12154027 trans-1,2-dichloroethene multiple interactions ISO RGD:2475 6480464 1 more ... CTD PMID:7871537 , PMID:9851676 trans-1,2-dichloroethene multiple interactions ISO RGD:10451 6480464 1 more ... CTD PMID:10828257 trans-1,2-dichloroethene decreases activity ISO RGD:2475 6480464 1, 2-dichloroethylene results in decreased activity of CYP2E1 protein CTD PMID:15205388 more ... trans-1,2-dichloroethene decreases expression ISO RGD:2475 6480464 1, 2-dichloroethylene results in decreased expression of CYP2E1 protein CTD PMID:9671540 trans-caffeic acid multiple interactions ISO RGD:2475 6480464 caffeic acid inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] CTD PMID:7710944 trans-cinnamic acid decreases activity EXP 6480464 cinnamic acid analog results in decreased activity of CYP2E1 protein CTD PMID:15072549 transfluthrin multiple interactions ISO RGD:2475 6480464 transfluthrin results in increased expression of and results in increased activity of CYP2E1 protein CTD PMID:22080754 tranylcypromine decreases activity EXP 6480464 Tranylcypromine results in decreased activity of CYP2E1 protein CTD PMID:15155557 triadimefon decreases expression ISO RGD:10451 6480464 triadimefon results in decreased expression of CYP2E1 mRNA CTD PMID:16730040 trichloroacetic acid multiple interactions EXP 6480464 [CYP2E1 protein results in increased oxidation of Tetrachloroethylene] which results in increased abundance of Trichloroacetic Acid, [CYP2E1 protein results in increased oxidation of Trichloroethylene] which results in increased abundance of Trichloroacetic Acid CTD PMID:29897530 trichloroethene increases activity EXP 6480464 Trichloroethylene results in increased activity of CYP2E1 protein CTD PMID:17710613 trichloroethene multiple interactions EXP 6480464 [CYP2E1 protein results in increased oxidation of Trichloroethylene] which results in increased abundance of Trichloroacetic Acid CTD PMID:29897530 trichloroethene increases activity ISO RGD:2475 6480464 Trichloroethylene results in increased activity of CYP2E1 protein CTD PMID:17710613 , PMID:8620572 trichloroethene increases metabolic processing ISO RGD:2475 6480464 CYP2E1 protein results in increased metabolism of Trichloroethylene CTD PMID:1739413 more ... trichloroethene increases metabolic processing ISO RGD:10451 6480464 CYP2E1 protein results in increased metabolism of Trichloroethylene CTD PMID:10774820 more ... trichloroethene increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of Trichloroethylene CTD PMID:1664256 , PMID:29897530 trichloroethene increases expression ISO RGD:2475 6480464 Trichloroethylene results in increased expression of CYP2E1 protein CTD PMID:8620572 trichloroethene affects metabolic processing ISO RGD:2475 6480464 CYP2E1 protein affects the metabolism of Trichloroethylene CTD PMID:17710613 , PMID:7871537 trichloroethene increases metabolic processing EXP 6480464 CYP2E1 protein results in increased metabolism of Trichloroethylene CTD PMID:10841534 , PMID:18350910 trichloroethene increases response to substance EXP 6480464 CYP2E1 gene polymorphism results in increased susceptibility to Trichloroethylene CTD PMID:19351467 trichloroethene increases response to substance ISO RGD:2475 6480464 CYP2E1 protein results in increased susceptibility to Trichloroethylene CTD PMID:17433522 trichloroethene multiple interactions ISO RGD:2475 6480464 1 more ... CTD PMID:1739413 more ... trichloroethene increases expression ISO RGD:10451 6480464 Trichloroethylene results in increased expression of CYP2E1 protein CTD PMID:10753203 trichloroethene multiple interactions ISO RGD:10451 6480464 [diallyl disulfide results in decreased expression of CYP2E1 protein] which results in decreased metabolism of and results in decreased susceptibility to Trichloroethylene CTD PMID:10774820 trichloroethene affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of Trichloroethylene CTD PMID:17710613 troglitazone increases expression ISO RGD:2475 6480464 troglitazone results in increased expression of CYP2E1 mRNA CTD PMID:21515302 troglitazone increases expression ISO RGD:10451 6480464 troglitazone results in increased expression of CYP2E1 mRNA CTD PMID:28973697 tryptamines multiple interactions EXP 6480464 [Tryptamines analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone CTD PMID:26599973 tryptamines decreases activity EXP 6480464 Tryptamines analog results in decreased activity of CYP2E1 protein CTD PMID:26599973 umbelliferone multiple interactions ISO RGD:10451 6480464 7-hydroxycoumarin inhibits the reaction [Dietary Fats results in increased activity of CYP2E1 protein] CTD PMID:24661945 uranium atom multiple interactions ISO RGD:2475 6480464 [Acetaminophen co-treated with Uranium analog] results in decreased expression of CYP2E1 mRNA, Uranium analog promotes the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA] CTD PMID:17126469 urethane multiple interactions ISO RGD:10451 6480464 1-aminobenzotriazole inhibits the reaction [CYP2E1 protein affects the metabolism of Urethane] more ... CTD PMID:12704224 more ... urethane increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of Urethane CTD PMID:1664256 urethane affects metabolic processing ISO RGD:10451 6480464 CYP2E1 protein affects the metabolism of Urethane CTD PMID:12704224 more ... urethane increases response to substance ISO RGD:10451 6480464 CYP2E1 protein results in increased susceptibility to Urethane CTD PMID:15790490 urethane affects oxidation ISO RGD:10451 6480464 CYP2E1 protein affects the oxidation of Urethane CTD PMID:20205516 urethane affects hydroxylation ISO RGD:10451 6480464 CYP2E1 protein affects the hydroxylation of Urethane CTD PMID:15879495 urethane decreases response to substance ISO RGD:10451 6480464 CYP2E1 gene mutant form results in decreased susceptibility to Urethane CTD PMID:17093202 urethane decreases metabolic processing ISO RGD:10451 6480464 CYP2E1 gene mutant form results in decreased metabolism of Urethane CTD PMID:12704224 ursodeoxycholic acid multiple interactions ISO RGD:2475 6480464 Ursodeoxycholic Acid inhibits the reaction [Deoxycholic Acid results in decreased expression of and results in decreased activity of CYP2E1 protein] CTD PMID:10453939 usnic acid multiple interactions EXP 6480464 [usnic acid co-treated with Lipopolysaccharides] results in decreased expression of CYP2E1 mRNA CTD PMID:22777745 usnic acid decreases expression EXP 6480464 usnic acid results in decreased expression of CYP2E1 mRNA CTD PMID:21953288 , PMID:22777745 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of CYP2E1 mRNA CTD PMID:29154799 , PMID:29501571 valproic acid decreases expression ISO RGD:2475 6480464 Valproic Acid results in decreased expression of CYP2E1 mRNA CTD PMID:17381134 vancomycin multiple interactions ISO RGD:2475 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2E1 mRNA CTD PMID:30545405 vanoxerine dihydrochloride multiple interactions EXP 6480464 [Chlorzoxazone results in decreased activity of CYP2E1 protein] which results in decreased degradation of vanoxerine CTD PMID:11502731 vanoxerine dihydrochloride decreases degradation EXP 6480464 CYP2E1 protein results in decreased degradation of vanoxerine CTD PMID:11502731 vinclozolin multiple interactions ISO RGD:10451 6480464 [acephate co-treated with vinclozolin] affects the expression of CYP2E1 protein more ... CTD PMID:17686559 vinclozolin increases expression ISO RGD:2475 6480464 vinclozolin results in increased expression of CYP2E1 protein CTD PMID:25929820 vinclozolin affects expression ISO RGD:10451 6480464 vinclozolin affects the expression of CYP2E1 mRNA, vinclozolin affects the expression of CYP2E1 protein CTD PMID:8921505 vinyl carbamate affects metabolic processing EXP 6480464 CYP2E1 protein affects the metabolism of vinyl carbamate CTD PMID:11181492 vinyl carbamate increases oxidation EXP 6480464 CYP2E1 protein results in increased oxidation of vinyl carbamate CTD PMID:1664256 vinyl carbamate affects oxidation ISO RGD:2475 6480464 CYP2E1 protein affects the oxidation of vinyl carbamate CTD PMID:17296623 vinyl carbamate multiple interactions ISO RGD:2475 6480464 diallyl sulfone inhibits the reaction [CYP2E1 protein affects the oxidation of vinyl carbamate] CTD PMID:17296623 vinyl carbamate decreases expression ISO RGD:10451 6480464 vinyl carbamate results in decreased expression of CYP2E1 protein CTD PMID:11134547 vinyl carbamate decreases activity ISO RGD:10451 6480464 vinyl carbamate results in decreased activity of CYP2E1 protein CTD PMID:11134547 vinyl carbamate multiple interactions ISO RGD:10451 6480464 [diallyl sulfone results in decreased activity of CYP2E1 protein] which affects the susceptibility to vinyl carbamate, diallyl sulfone inhibits the reaction [CYP2E1 protein affects the oxidation of vinyl carbamate] CTD PMID:17341656 , PMID:20205516 vinyl carbamate affects oxidation ISO RGD:10451 6480464 CYP2E1 protein affects the oxidation of vinyl carbamate CTD PMID:20205516 vinyl carbamate affects metabolic processing ISO RGD:10451 6480464 CYP2E1 protein affects the metabolism of vinyl carbamate CTD PMID:11181492 vinyl carbamate multiple interactions EXP 6480464 [vinyl carbamate co-treated with NADP] inhibits the reaction [CYP2E1 protein results in decreased methylation of Dimethylnitrosamine] CTD PMID:11181492 vitamin E increases expression ISO RGD:2475 6480464 alpha-Tocopherol results in increased expression of CYP2E1 mRNA CTD PMID:26332274 vitamin E increases expression EXP 6480464 alpha-Tocopherol results in increased expression of CYP2E1 mRNA CTD PMID:28062356 vitamin E multiple interactions ISO RGD:2475 6480464 [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein] more ... CTD PMID:25439240 more ... vitamin E multiple interactions EXP 6480464 Vitamin E inhibits the reaction [CYP2E1 protein results in increased expression of COL1A2 mRNA] CTD PMID:10498651 wortmannin multiple interactions ISO RGD:2475 6480464 wortmannin inhibits the reaction [INS1 protein results in decreased expression of CYP2E1 mRNA] CTD PMID:11306697 Wuweizisu C decreases activity ISO RGD:10451 6480464 schizandrin C results in decreased activity of CYP2E1 protein CTD PMID:25753323 XL147 multiple interactions ISO RGD:10451 6480464 [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CYP2E1 mRNA CTD PMID:27935865 zearalenone increases expression ISO RGD:2475 6480464 Zearalenone results in increased expression of CYP2E1 mRNA CTD PMID:20607812 zinc atom multiple interactions ISO RGD:2475 6480464 [Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP2E1 protein] more ... CTD PMID:21424224 , PMID:27919644 zinc atom multiple interactions ISO RGD:10451 6480464 [Zinc deficiency co-treated with Ethanol] results in increased expression of CYP2E1 protein CTD PMID:24155903 zinc atom increases expression ISO RGD:10451 6480464 Zinc deficiency results in increased expression of CYP2E1 protein CTD PMID:24155903 zinc diethyldithiocarbamate decreases activity EXP 6480464 Ditiocarb results in decreased activity of CYP2E1 protein CTD PMID:15306208 more ... zinc diethyldithiocarbamate multiple interactions ISO RGD:10451 6480464 [Ditiocarb co-treated with CYP2E1 gene mutant form] results in decreased metabolism of Styrene, [Ditiocarb results in decreased activity of CYP2E1 protein] which results in decreased oxidation of Benzene CTD PMID:12746132 , PMID:8560479 zinc diethyldithiocarbamate multiple interactions ISO RGD:2475 6480464 Ditiocarb inhibits the reaction [[Benzene results in increased expression of CYP2E1 protein] which results in increased metabolism of Benzene] more ... CTD PMID:1538706 more ... zinc diethyldithiocarbamate decreases activity ISO RGD:2475 6480464 Ditiocarb results in decreased activity of CYP2E1 protein CTD PMID:1356728 zinc diethyldithiocarbamate multiple interactions EXP 6480464 Ditiocarb inhibits the reaction [CYP2E1 protein results in increased glutathionylation of Lamotrigine] more ... CTD PMID:10215755 more ... zinc protoporphyrin multiple interactions ISO RGD:2475 6480464 [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP2E1 mRNA more ... CTD PMID:26747958 zinc protoporphyrin multiple interactions EXP 6480464 zinc protoporphyrin inhibits the reaction [Quercetin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]], zinc protoporphyrin inhibits the reaction [tricarbonyldichlororuthenium (II) dimer inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]] CTD PMID:19325051 zinc sulfate multiple interactions ISO RGD:10451 6480464 [Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein] more ... CTD PMID:15920153 , PMID:20118189 zinc sulfate increases expression ISO RGD:2475 6480464 Zinc Sulfate results in increased expression of CYP2E1 mRNA CTD PMID:20553223 zinc sulfate multiple interactions ISO RGD:2475 6480464 Paraquat promotes the reaction [Zinc Sulfate results in increased expression of CYP2E1 mRNA], Zinc Sulfate promotes the reaction [Paraquat results in increased expression of CYP2E1 mRNA] CTD PMID:20553223 zinc sulfate multiple interactions EXP 6480464 CYP2E1 results in increased susceptibility to [Arachidonic Acid co-treated with Zinc Sulfate] more ... CTD PMID:12566070 zinc(0) multiple interactions ISO RGD:2475 6480464 [Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP2E1 protein] more ... CTD PMID:21424224 , PMID:27919644 zinc(0) increases expression ISO RGD:10451 6480464 Zinc deficiency results in increased expression of CYP2E1 protein CTD PMID:24155903 zinc(0) multiple interactions ISO RGD:10451 6480464 [Zinc deficiency co-treated with Ethanol] results in increased expression of CYP2E1 protein CTD PMID:24155903 zingerone multiple interactions ISO RGD:2475 6480464 zingerone inhibits the reaction [1 more ... CTD PMID:28442378 , PMID:30720227
Gene-Chemical Interaction Annotations