Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Fer | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of FER mRNA] | CTD | PMID:31150632 | Fer | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | FER (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of FER mRNA | CTD | PMID:22079256 | Fer | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Fer (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of FER mRNA | CTD | PMID:17942748 | Fer | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Fer (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FER mRNA | CTD | PMID:17942748 | Fer | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Fer (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of FER mRNA | CTD | PMID:21570461 | Fer | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FER mRNA | CTD | PMID:32109520 | Fer | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Fer (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FER mRNA | CTD | PMID:17942748 | Fer | Rat | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | Fer | Rat | 4,4'-diaminodiphenylmethane | increases expression | ISO | Fer (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of FER mRNA | CTD | PMID:18648102 | Fer | Rat | acetylsalicylic acid | decreases expression | ISO | FER (Homo sapiens) | 6480464 | Aspirin results in decreased expression of FER mRNA | CTD | PMID:15456535 | Fer | Rat | aflatoxin B1 | increases expression | ISO | Fer (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of FER mRNA | CTD | PMID:19770486 | Fer | Rat | aflatoxin B1 | increases methylation | ISO | FER (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of FER intron | CTD | PMID:30157460 | Fer | Rat | aflatoxin B1 | decreases methylation | ISO | FER (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of FER gene | CTD | PMID:27153756 | Fer | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of FER mRNA | CTD | PMID:16483693 | Fer | Rat | aristolochic acid A | decreases expression | ISO | FER (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of FER mRNA | CTD | PMID:33212167 | Fer | Rat | arsane | affects methylation | ISO | FER (Homo sapiens) | 6480464 | Arsenic affects the methylation of FER gene | CTD | PMID:25304211 | Fer | Rat | arsenic atom | affects methylation | ISO | FER (Homo sapiens) | 6480464 | Arsenic affects the methylation of FER gene | CTD | PMID:25304211 | Fer | Rat | arsenite(3-) | multiple interactions | ISO | FER (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to FER mRNA] | CTD | PMID:32406909 | Fer | Rat | arsenous acid | increases expression | ISO | FER (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of FER mRNA | CTD | PMID:29633893 | Fer | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of FER gene | CTD | PMID:28931070 | Fer | Rat | benzo[a]pyrene | affects expression | ISO | FER (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the expression of FER mRNA | CTD | PMID:21714911 | Fer | Rat | benzo[a]pyrene | affects methylation | ISO | FER (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of FER promoter | CTD | PMID:27901495 | Fer | Rat | benzo[a]pyrene | increases expression | ISO | FER (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of FER mRNA | CTD | PMID:26238291 | Fer | Rat | benzo[a]pyrene | decreases expression | ISO | Fer (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of FER mRNA | CTD | PMID:21715664 | Fer | Rat | benzo[a]pyrene | decreases expression | ISO | FER (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of FER mRNA | CTD | PMID:20106945 | Fer | Rat | Benzo[k]fluoranthene | decreases expression | ISO | Fer (Mus musculus) | 6480464 | benzo(k)fluoranthene results in decreased expression of FER mRNA | CTD | PMID:26377693 | Fer | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of FER mRNA | CTD | PMID:25181051 more ... | Fer | Rat | bisphenol A | multiple interactions | ISO | FER (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of FER gene | CTD | PMID:31601247 | Fer | Rat | bisphenol A | increases expression | ISO | FER (Homo sapiens) | 6480464 | bisphenol A results in increased expression of FER mRNA | CTD | PMID:33670352 | Fer | Rat | bisphenol A | decreases expression | ISO | Fer (Mus musculus) | 6480464 | bisphenol A results in decreased expression of FER mRNA | CTD | PMID:33221593 | Fer | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of FER gene | CTD | PMID:28505145 | Fer | Rat | cadmium dichloride | increases expression | ISO | FER (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of FER mRNA | CTD | PMID:21457566 | Fer | Rat | caffeine | decreases phosphorylation | ISO | FER (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of FER protein | CTD | PMID:35688186 | Fer | Rat | carbamazepine | affects expression | ISO | FER (Homo sapiens) | 6480464 | Carbamazepine affects the expression of FER mRNA | CTD | PMID:24752500 | Fer | Rat | carbon nanotube | increases expression | ISO | Fer (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | Fer | Rat | cisplatin | decreases expression | ISO | FER (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of FER mRNA | CTD | PMID:27392435 | Fer | Rat | cisplatin | multiple interactions | ISO | FER (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of FER mRNA | CTD | PMID:27392435 | Fer | Rat | crocidolite asbestos | decreases expression | ISO | Fer (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of FER mRNA | CTD | PMID:29279043 | Fer | Rat | cyclosporin A | increases expression | ISO | FER (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of FER mRNA | CTD | PMID:25562108 | Fer | Rat | diarsenic trioxide | increases expression | ISO | FER (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of FER mRNA | CTD | PMID:29633893 | Fer | Rat | diclofenac | affects expression | ISO | FER (Homo sapiens) | 6480464 | Diclofenac affects the expression of FER mRNA | CTD | PMID:24752500 | Fer | Rat | dicrotophos | decreases expression | ISO | FER (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of FER mRNA | CTD | PMID:28302478 | Fer | Rat | dimethylarsinous acid | decreases expression | ISO | FER (Homo sapiens) | 6480464 | dimethylarsinous acid results in decreased expression of FER mRNA | CTD | PMID:23487506 | Fer | Rat | dorsomorphin | multiple interactions | ISO | FER (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Fer | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of FER mRNA | CTD | PMID:29391264 | Fer | Rat | FR900359 | decreases phosphorylation | ISO | FER (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of FER protein | CTD | PMID:37730182 | Fer | Rat | fulvestrant | multiple interactions | ISO | FER (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of FER gene | CTD | PMID:31601247 | Fer | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of FER mRNA | CTD | PMID:33387578 | Fer | Rat | glycidol | decreases expression | EXP | | 6480464 | glycidol results in decreased expression of FER mRNA | CTD | PMID:24395379 | Fer | Rat | glyphosate | affects methylation | EXP | | 6480464 | Glyphosate affects the methylation of FER gene | CTD | PMID:35440735 | Fer | Rat | lead(0) | affects splicing | ISO | FER (Homo sapiens) | 6480464 | Lead affects the splicing of FER mRNA | CTD | PMID:28903495 | Fer | Rat | methotrexate | affects response to substance | ISO | FER (Homo sapiens) | 6480464 | FER protein affects the susceptibility to Methotrexate | CTD | PMID:16217747 | Fer | Rat | methyl methanesulfonate | increases expression | ISO | FER (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of FER mRNA | CTD | PMID:23649840 | Fer | Rat | methylmercury chloride | decreases expression | ISO | FER (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of FER mRNA | CTD | PMID:28001369 | Fer | Rat | O-methyleugenol | decreases expression | ISO | FER (Homo sapiens) | 6480464 | methyleugenol results in decreased expression of FER mRNA | CTD | PMID:32234424 | Fer | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of FER mRNA | CTD | PMID:33387578 | Fer | Rat | phenylmercury acetate | increases expression | ISO | FER (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of FER mRNA | CTD | PMID:26272509 | Fer | Rat | phenylmercury acetate | multiple interactions | ISO | FER (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FER mRNA | CTD | PMID:27188386 | Fer | Rat | pirinixic acid | multiple interactions | ISO | FER (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of FER mRNA | CTD | PMID:19710929 | Fer | Rat | potassium chromate | decreases expression | ISO | FER (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of FER mRNA | CTD | PMID:22079256 | Fer | Rat | potassium chromate | multiple interactions | ISO | FER (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of FER mRNA | CTD | PMID:22079256 | Fer | Rat | resveratrol | multiple interactions | ISO | FER (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of FER mRNA | CTD | PMID:23557933 | Fer | Rat | SB 431542 | multiple interactions | ISO | FER (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Fer | Rat | sunitinib | increases expression | ISO | FER (Homo sapiens) | 6480464 | Sunitinib results in increased expression of FER mRNA | CTD | PMID:31533062 | Fer | Rat | tetrachloromethane | decreases expression | ISO | Fer (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of FER mRNA | CTD | PMID:17484886 | Fer | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of FER mRNA] | CTD | PMID:31150632 | Fer | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of FER mRNA | CTD | PMID:31150632 | Fer | Rat | thimerosal | increases expression | ISO | FER (Homo sapiens) | 6480464 | Thimerosal results in increased expression of FER mRNA | CTD | PMID:27188386 | Fer | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of FER mRNA | CTD | PMID:34492290 | Fer | Rat | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of FER gene | CTD | PMID:27618143 | Fer | Rat | trichostatin A | increases expression | ISO | FER (Homo sapiens) | 6480464 | trichostatin A results in increased expression of FER mRNA | CTD | PMID:26272509 | Fer | Rat | trichostatin A | multiple interactions | ISO | FER (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FER mRNA | CTD | PMID:27188386 | Fer | Rat | triphenyl phosphate | affects expression | ISO | FER (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of FER mRNA | CTD | PMID:37042841 | Fer | Rat | troglitazone | decreases expression | ISO | Fer (Mus musculus) | 6480464 | troglitazone results in decreased expression of FER mRNA | CTD | PMID:28973697 | Fer | Rat | valproic acid | decreases methylation | ISO | FER (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of FER gene | CTD | PMID:29154799 | Fer | Rat | valproic acid | multiple interactions | ISO | FER (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FER mRNA | CTD | PMID:27188386 | Fer | Rat | valproic acid | increases expression | ISO | FER (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of FER mRNA | CTD | PMID:23179753 more ... | Fer | Rat | valproic acid | affects expression | ISO | FER (Homo sapiens) | 6480464 | Valproic Acid affects the expression of FER mRNA | CTD | PMID:25979313 | Fer | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of FER mRNA | CTD | PMID:22570695 | |