Csk (C-terminal Src kinase) - Rat Genome Database

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Gene: Csk (C-terminal Src kinase) Ictidomys tridecemlineatus
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Symbol: Csk
Name: C-terminal Src kinase
RGD ID: 12564546
Description: ENCODES a protein that exhibits identical protein binding (ortholog); proline-rich region binding (ortholog); protein kinase A catalytic subunit binding (ortholog); INVOLVED IN adherens junction organization (ortholog); brain development (ortholog); cellular response to peptide hormone stimulus (ortholog); PARTICIPATES IN platelet-derived growth factor signaling pathway; ASSOCIATED WITH Bloom syndrome (ortholog); colon cancer (ortholog); dermatitis (ortholog); FOUND IN cell-cell junction (ortholog); cytoplasm (ortholog); membrane raft (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: c-src tyrosine kinase; CSK, non-receptor tyrosine kinase; tyrosine-protein kinase CSK
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640115,909,712 - 115,929,808 (+)NCBI
SpeTri2.0NW_00493647133,757,778 - 33,777,871 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Csk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640115,909,712 - 115,929,808 (+)NCBI
SpeTri2.0NW_00493647133,757,778 - 33,777,871 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CSK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1574,782,080 - 74,803,197 (+)EnsemblGRCh38hg38GRCh38
GRCh381574,782,080 - 74,803,197 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371575,074,421 - 75,095,538 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361572,861,768 - 72,882,558 (+)NCBINCBI36hg18NCBI36
Build 341572,861,767 - 72,882,557NCBI
Celera1552,024,458 - 52,045,568 (+)NCBI
Cytogenetic Map15q24.1NCBI
HuRef1551,872,089 - 51,892,744 (+)NCBIHuRef
CHM1_11575,192,927 - 75,214,023 (+)NCBICHM1_1
Csk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39957,533,929 - 57,560,914 (-)NCBIGRCm39mm39
GRCm39 Ensembl957,533,929 - 57,560,914 (-)Ensembl
GRCm38957,626,646 - 57,653,631 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl957,626,646 - 57,653,631 (-)EnsemblGRCm38mm10GRCm38
MGSCv37957,474,453 - 57,492,987 (-)NCBIGRCm37mm9NCBIm37
MGSCv36957,424,783 - 57,443,317 (-)NCBImm8
Celera954,862,569 - 54,881,336 (-)NCBICelera
Cytogenetic Map9BNCBI
cM Map931.18NCBI
Csk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2858,029,748 - 58,048,742 (-)NCBI
Rnor_6.0 Ensembl862,405,715 - 62,424,303 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0862,405,714 - 62,424,707 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0862,183,286 - 62,208,785 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4861,381,336 - 61,386,013 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1861,400,389 - 61,405,067 (-)NCBI
Celera857,495,667 - 57,500,290 (-)NCBICelera
Cytogenetic Map8q24NCBI
Csk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554503,127,561 - 3,144,550 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554503,127,561 - 3,144,550 (-)NCBIChiLan1.0ChiLan1.0
CSK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11573,342,703 - 73,363,476 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1573,342,703 - 73,363,476 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01553,724,814 - 53,745,710 (+)NCBIMhudiblu_PPA_v0panPan3
CSK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13037,851,269 - 37,870,382 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3037,852,046 - 37,870,378 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3037,784,125 - 37,802,413 (+)NCBI
ROS_Cfam_1.03038,056,541 - 38,074,206 (+)NCBI
UMICH_Zoey_3.13038,009,325 - 38,027,610 (+)NCBI
UNSW_CanFamBas_1.03038,055,644 - 38,073,934 (+)NCBI
UU_Cfam_GSD_1.03038,291,119 - 38,309,429 (+)NCBI
CSK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl758,736,529 - 58,755,260 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1758,736,473 - 58,755,034 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2763,425,071 - 63,443,632 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CSK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1268,667,657 - 8,688,850 (-)NCBI
ChlSab1.1 Ensembl268,667,655 - 8,688,824 (-)Ensembl
Vero_WHO_p1.0NW_023666048132,942,200 - 132,963,400 (+)NCBI
Csk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462489412,621 - 29,400 (+)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005316802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010003700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005316802   ⟹   XP_005316859
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640115,909,712 - 115,929,808 (+)NCBI
SpeTri2.0NW_00493647133,757,778 - 33,777,871 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005316859 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3262290 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005316859   ⟸   XM_005316802
- UniProtKB: I3N6S6 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Protein kinase   SH2   SH3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000022236 ENTREZGENE
Ensembl Protein ENSSTOP00000020072 ENTREZGENE
NCBI Gene Csk ENTREZGENE
UniProt I3N6S6 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-16 Csk  C-terminal Src kinase    CSK, non-receptor tyrosine kinase  Symbol and/or name change 5135510 APPROVED
2017-02-14 Csk  CSK, non-receptor tyrosine kinase    c-src tyrosine kinase  Symbol and/or name change 5135510 APPROVED