Gene: Pml (promyelocytic leukemia) Rattus norvegicus
Symbol: Pml
Name: promyelocytic leukemia
Description: ENCODES a protein that exhibits cobalt ion binding (ortholog); protein heterodimerization activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN activation of cysteine-type endopeptidase activity involved in apoptotic process (ortholog); apoptotic process (ortholog); branching involved in mammary gland duct morphogenesis (ortholog); PARTICIPATES IN mTOR signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; acute myeloid leukemia pathway; ASSOCIATED WITH Carcinoma, Ductal, Breast (ortholog); Glioblastoma (ortholog); Leukemia, Promyelocytic, Acute (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); extrinsic component of endoplasmic reticulum membrane (ortholog); INTERACTS WITH 3,3',5,5'-tetrabromobisphenol A; 6-propyl-2-thiouracil; bisphenol A
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC315713; RGD1562602; similar to promyelocytic leukemia
Homo sapiens (human) : PML (promyelocytic leukemia)  HGNC  AGR
Mus musculus (house mouse) : Pml (promyelocytic leukemia)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Pml (promyelocytic leukemia)
Pan paniscus (bonobo/pygmy chimpanzee) : PML (promyelocytic leukemia)
Canis lupus familiaris (dog) : PML (promyelocytic leukemia)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pml (promyelocytic leukemia)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0863,002,515 - 63,034,310 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0862,778,563 - 62,810,283 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4862,020,438 - 62,051,927 (-)NCBIRGSC3.4rn4RGSC3.4
Celera858,089,954 - 58,121,691 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Pml
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1562602
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE