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Gene: Pml (promyelocytic leukemia) Rattus norvegicus
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Symbol: Pml
Name: promyelocytic leukemia
Description: Predicted to have several functions, including protein dimerization activity; transition metal ion binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including apoptotic signaling pathway; regulation of cellular protein metabolic process; and regulation of nucleobase-containing compound metabolic process. Predicted to colocalize with the heterochromatin. Orthologous to human PML (promyelocytic leukemia); PARTICIPATES IN mTOR signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; acute myeloid leukemia pathway; INTERACTS WITH (RS)-amphetamine; 3,3',5,5'-tetrabromobisphenol A; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC315713; RGD1562602; similar to promyelocytic leukemia
Orthologs:
Homo sapiens (human) : PML (promyelocytic leukemia)  HGNC  Alliance
Mus musculus (house mouse) : Pml (promyelocytic leukemia)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pml (promyelocytic leukemia)
Pan paniscus (bonobo/pygmy chimpanzee) : PML (promyelocytic leukemia)
Canis lupus familiaris (dog) : PML (promyelocytic leukemia)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pml (promyelocytic leukemia)
Sus scrofa (pig) : PML (promyelocytic leukemia)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0863,002,515 - 63,034,310 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0862,778,563 - 62,810,283 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4862,020,438 - 62,051,927 (-)NCBIRGSC3.4rn4RGSC3.4
Celera858,089,954 - 58,121,691 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Pml
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1562602
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.