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Gene: Pml (PML nuclear body scaffold) Rattus norvegicus
Symbol: Pml
Name: PML nuclear body scaffold
RGD ID: 1562602
Description: Predicted to have several functions, including protein dimerization activity; sumo-dependent protein binding activity; and transition metal ion binding activity. Predicted to be involved in several processes, including apoptotic signaling pathway; regulation of cellular protein metabolic process; and regulation of nucleobase-containing compound metabolic process. Predicted to colocalize with heterochromatin. Orthologous to human PML (PML nuclear body scaffold); PARTICIPATES IN mTOR signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; acute myeloid leukemia pathway; INTERACTS WITH 3,3',5,5'-tetrabromobisphenol A; 6-propyl-2-thiouracil; amphetamine.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC315713; promyelocytic leukemia; RGD1562602; similar to promyelocytic leukemia
Homo sapiens (human) : PML (PML nuclear body scaffold)  HGNC  Alliance
Mus musculus (house mouse) : Pml (promyelocytic leukemia)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pml (PML nuclear body scaffold)
Pan paniscus (bonobo/pygmy chimpanzee) : PML (PML nuclear body scaffold)
Canis lupus familiaris (dog) : PML (PML nuclear body scaffold)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pml (PML nuclear body scaffold)
Sus scrofa (pig) : PML (PML nuclear body scaffold)
Chlorocebus sabaeus (African green monkey) : PML (PML nuclear body scaffold)
Heterocephalus glaber (naked mole-rat) : Pml (PML nuclear body scaffold)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0863,002,515 - 63,034,310 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl863,004,870 - 63,034,226 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0862,778,563 - 62,810,283 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4862,020,438 - 62,051,927 (-)NCBIRGSC3.4rn4RGSC3.4
Celera858,089,954 - 58,121,691 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Pml
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1562602
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-11-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.